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The map label for this gene is yvoA [H]

Identifier: 51596509

GI number: 51596509

Start: 2569923

End: 2570747

Strand: Direct

Name: yvoA [H]

Synonym: YPTB2183

Alternate gene names: 51596509

Gene position: 2569923-2570747 (Clockwise)

Preceding gene: 51596507

Following gene: 51596512

Centisome position: 54.16

GC content: 47.15

Gene sequence:

>825_bases
ATGATGACAATCACTGTTCCCTGGATAACAATTGGTTCACTCACTCTGAACCAGACAGGACAATCACGAAGCCTGATGAA
TACATCTCCAGCACCTGAATTTCACCTTGATAAATCCAGTAGATTGCCACTCTATTTGCAACTGGTTAATTCCATAAAAT
CTGCAATTACTGAAGGGCGTTTACATGCAGGTGATGTTTTGCCACCAGAGCGGGAACTGGCAGAGATGCTGGATATTGCG
CGGGGGACTGTTCGTAAAGCCTTACTACAGCTACTTGAAGGCGGCGTTCTTGTACGCAATCAGGGCGTTGGTACATTTAT
TGCGCCGCATGTATGCCCGTCGTTGCCGCTACTGGAGAGTTTTAGTGAAATGGCTACGGCCAGCGGAGGTACGGCGCAAA
GTGAACTGTTGGGATATCTGCGGCGCCCATCCGCACTGGAAGAACGTAGTGTCTTGCAAATGACACAGGATAATGGCGAC
GTCGTGGAACTGACCAGACTCAGAAAGGTTAATGGTATTACTGTTTCCCTCCAGATTGCGATTTTACCGGCGCATTTTCT
GGATAACATCAGTGAACTCGATGAGTCTTTGTATTGGCATCTGGAAAAAAAGGGAGCACAAGTATTGCGGGCAACCCAGC
ACTTCAGCGCAGCAGTTACGGACAGTACATTGGCGCACTACTTGGGCACCGATGAGTATGAGCCCGTTTTACTAGTAACC
CGAACAGGCTTTACTCATAACGATCGGCCTGTTGAATATACCCGAACCTGGTATCTTAACGATTACTGTGATTTTACGAT
TGATCTACACCGTAAAGATCTATAA

Upstream 100 bases:

>100_bases
TACCTTTAGTGAACCTTACATGAATGGCCTCTGTTATCTGTAGTTCCATCTGTTTGTTTTGTGATCTGAGTTACTTTAAA
GGTTTTGCCCTGTCATTTTG

Downstream 100 bases:

>100_bases
ATACAAAAAGCAGATTTGAACGTTGCTTACAGCGGCCTCGAAGAGGCGAAGCCCATAGATGGGGGGAGTAACGAACGCAG
CCAACGCACATGCAGTTTGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MMTITVPWITIGSLTLNQTGQSRSLMNTSPAPEFHLDKSSRLPLYLQLVNSIKSAITEGRLHAGDVLPPERELAEMLDIA
RGTVRKALLQLLEGGVLVRNQGVGTFIAPHVCPSLPLLESFSEMATASGGTAQSELLGYLRRPSALEERSVLQMTQDNGD
VVELTRLRKVNGITVSLQIAILPAHFLDNISELDESLYWHLEKKGAQVLRATQHFSAAVTDSTLAHYLGTDEYEPVLLVT
RTGFTHNDRPVEYTRTWYLNDYCDFTIDLHRKDL

Sequences:

>Translated_274_residues
MMTITVPWITIGSLTLNQTGQSRSLMNTSPAPEFHLDKSSRLPLYLQLVNSIKSAITEGRLHAGDVLPPERELAEMLDIA
RGTVRKALLQLLEGGVLVRNQGVGTFIAPHVCPSLPLLESFSEMATASGGTAQSELLGYLRRPSALEERSVLQMTQDNGD
VVELTRLRKVNGITVSLQIAILPAHFLDNISELDESLYWHLEKKGAQVLRATQHFSAAVTDSTLAHYLGTDEYEPVLLVT
RTGFTHNDRPVEYTRTWYLNDYCDFTIDLHRKDL
>Mature_274_residues
MMTITVPWITIGSLTLNQTGQSRSLMNTSPAPEFHLDKSSRLPLYLQLVNSIKSAITEGRLHAGDVLPPERELAEMLDIA
RGTVRKALLQLLEGGVLVRNQGVGTFIAPHVCPSLPLLESFSEMATASGGTAQSELLGYLRRPSALEERSVLQMTQDNGD
VVELTRLRKVNGITVSLQIAILPAHFLDNISELDESLYWHLEKKGAQVLRATQHFSAAVTDSTLAHYLGTDEYEPVLLVT
RTGFTHNDRPVEYTRTWYLNDYCDFTIDLHRKDL

Specific function: Acts as a weak repressor of yflG expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=227, Percent_Identity=29.0748898678414, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=29.3617021276596, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082252, Length=242, Percent_Identity=23.5537190082645, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790540, Length=218, Percent_Identity=30.2752293577982, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790118, Length=224, Percent_Identity=24.5535714285714, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 30526; Mature: 30526

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTITVPWITIGSLTLNQTGQSRSLMNTSPAPEFHLDKSSRLPLYLQLVNSIKSAITEGR
CEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCC
LHAGDVLPPERELAEMLDIARGTVRKALLQLLEGGVLVRNQGVGTFIAPHVCPSLPLLES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHCCCCHHHHH
FSEMATASGGTAQSELLGYLRRPSALEERSVLQMTQDNGDVVELTRLRKVNGITVSLQIA
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHCCCEEEEEEEE
ILPAHFLDNISELDESLYWHLEKKGAQVLRATQHFSAAVTDSTLAHYLGTDEYEPVLLVT
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RTGFTHNDRPVEYTRTWYLNDYCDFTIDLHRKDL
ECCCCCCCCCCEEEEEEEECCCCCEEEEECCCCC
>Mature Secondary Structure
MMTITVPWITIGSLTLNQTGQSRSLMNTSPAPEFHLDKSSRLPLYLQLVNSIKSAITEGR
CEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHCCC
LHAGDVLPPERELAEMLDIARGTVRKALLQLLEGGVLVRNQGVGTFIAPHVCPSLPLLES
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECHHHCCCCHHHHH
FSEMATASGGTAQSELLGYLRRPSALEERSVLQMTQDNGDVVELTRLRKVNGITVSLQIA
HHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEHHHHHHCCCEEEEEEEE
ILPAHFLDNISELDESLYWHLEKKGAQVLRATQHFSAAVTDSTLAHYLGTDEYEPVLLVT
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
RTGFTHNDRPVEYTRTWYLNDYCDFTIDLHRKDL
ECCCCCCCCCCEEEEEEEECCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]