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The map label for this gene is mviN

Identifier: 51596352

GI number: 51596352

Start: 2383495

End: 2385030

Strand: Direct

Name: mviN

Synonym: YPTB2026

Alternate gene names: 51596352

Gene position: 2383495-2385030 (Clockwise)

Preceding gene: 51596351

Following gene: 51596353

Centisome position: 50.24

GC content: 51.17

Gene sequence:

>1536_bases
ATGAATCTATTGAAATCACTGGCCGCCGTCAGTTCCATGACGATGTTTTCCCGCGTGCTGGGCTTTGCCCGCGATGCCAT
CGTGGCACGGGTATTTGGTGCAGGTATGGCGACGGACGCCTTTTTTGTGGCATTTAAATTGCCTAACTTGCTGCGGCGAA
TATTTGCTGAAGGCGCATTTTCCCAAGCTTTTGTGCCTATTCTGGCTGAATACAAAAGCCAGCAAGGGGAAGAGGCGACG
CGAACATTAGTGGCTTATGTCTCTGGCCTGTTAACCTTGATATTGGCGGTCGTCACCGTCGCGGGGATGCTGGCCGCGCC
TTGGGTGATCTTCATTTCCGCCCCCGGCTTTACTGATACACCGGATAAATTTGCTCTGACCTCGGCGCTGTTACGGGTGA
CTTTCCCGTATATTTTGCTGATCTCATTGGCCTCGCTAGTCGGAGCGATCCTTAATACCTGGAACCGTTTTTCTATTCCG
GCTTTTGCGCCAACCCTCCTCAATGTCAGCATGATAGGTTTTGCGCTGTTTGCTGCGCCTCATTTCAACCCGCCGGTGAT
GGCATTGGCTTGGGCTGTGGTGGTGGGGGGAGTGTTACAATTAGGCTATCAACTCCCGCACCTAAAAAAAATCGGCATGT
TGGTATTACCTCGGCTGTCGCTACGTGATACCGGTGTTTGGCGGGTGATGCGCCAGATGGGGCCAGCGATCCTCGGGGTA
TCAGTCAGTCAGATTTCCCTGATTATCAATACGATTTTTGCATCATTTTTGGTATCTGGTTCGGTCTCCTGGATGTACTA
CGCTGACCGTCTGATGGAGTTCCCCTCCGGGGTGTTAGGGGGCGCGTTAGGTACTATCCTGCTGCCATCACTGGCAAAGA
GTTTTTCCAGTGCTAATCATGATGAATATTCCAGATTGATGGATTGGGGGCTGCGTCTTTGCTTCTTACTGGCCTTGCCA
AGCGCGGTGGCATTAGGAATTTTAGCTAAACCGCTAATCGTCTCGTTATTCCAATACGGGAAATTTAGCGCGTTTGACAC
CCTGATGACACAACGGGCGCTGGTGGCCTATTCGGTGGGCTTGATGGGGTTGATCGTGGTGAAGGTTCTGGCTCCGGGGT
TTTATTCTCGTCAGAATATTAAAACGCCGGTAAAAATCGCGATTATTACCTTGATACTCACGCAAGTCATGAACTTGATC
TTCATTGGGCCGTTTAAACACGCGGGCTTATCACTGTCTATCGGCCTGGGGGCATGTCTGAATGCCAGTTTGCTCTATTG
GCAGCTACGTAAACAGAAAATTTTCCAGCCACAGCCGGGGTGGGCCATATTCCTGACTAAATTGGTCATCGGTGTTATCG
CGATGTCTGCGGTGCTGCTAGGGTTACTGTGGGTCATGCCTGATTGGGATGTTGGCGGGATGGCGTATCGGTTGCTACGG
TTATCTGCGGTTGTTGTTGCCGGTGCTAGCGCCTACTTTGCCATGTTGGCATTATTAGGCTTTAAAGTGCGTGATTTTGC
CCGTAGAACGGGCTGA

Upstream 100 bases:

>100_bases
GCCGTGTTGATAACGGCGAATCCCCCATTGGGTAGAGCAACGCCTGCAGACCGTAGGCGTTGGTATTTACAGCACATTAG
AAAACAGATCAAAAGAACCT

Downstream 100 bases:

>100_bases
CCTTACTAATCAACTAATCAACTAATCAACTAATCAATCAGTATTGGTAATCTAAATAAACAATGTATTATATAGCCCGA
TAATTTCGGGCTTTTTTACA

Product: virulence factor mviN, MOP superfamliy efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPILAEYKSQQGEEAT
RTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSALLRVTFPYILLISLASLVGAILNTWNRFSIP
AFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLKKIGMLVLPRLSLRDTGVWRVMRQMGPAILGV
SVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLPSLAKSFSSANHDEYSRLMDWGLRLCFLLALP
SAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKVLAPGFYSRQNIKTPVKIAIITLILTQVMNLI
FIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLVIGVIAMSAVLLGLLWVMPDWDVGGMAYRLLR
LSAVVVAGASAYFAMLALLGFKVRDFARRTG

Sequences:

>Translated_511_residues
MNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPILAEYKSQQGEEAT
RTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSALLRVTFPYILLISLASLVGAILNTWNRFSIP
AFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLKKIGMLVLPRLSLRDTGVWRVMRQMGPAILGV
SVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLPSLAKSFSSANHDEYSRLMDWGLRLCFLLALP
SAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKVLAPGFYSRQNIKTPVKIAIITLILTQVMNLI
FIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLVIGVIAMSAVLLGLLWVMPDWDVGGMAYRLLR
LSAVVVAGASAYFAMLALLGFKVRDFARRTG
>Mature_511_residues
MNLLKSLAAVSSMTMFSRVLGFARDAIVARVFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPILAEYKSQQGEEAT
RTLVAYVSGLLTLILAVVTVAGMLAAPWVIFISAPGFTDTPDKFALTSALLRVTFPYILLISLASLVGAILNTWNRFSIP
AFAPTLLNVSMIGFALFAAPHFNPPVMALAWAVVVGGVLQLGYQLPHLKKIGMLVLPRLSLRDTGVWRVMRQMGPAILGV
SVSQISLIINTIFASFLVSGSVSWMYYADRLMEFPSGVLGGALGTILLPSLAKSFSSANHDEYSRLMDWGLRLCFLLALP
SAVALGILAKPLIVSLFQYGKFSAFDTLMTQRALVAYSVGLMGLIVVKVLAPGFYSRQNIKTPVKIAIITLILTQVMNLI
FIGPFKHAGLSLSIGLGACLNASLLYWQLRKQKIFQPQPGWAIFLTKLVIGVIAMSAVLLGLLWVMPDWDVGGMAYRLLR
LSAVVVAGASAYFAMLALLGFKVRDFARRTG

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=510, Percent_Identity=85.2941176470588, Blast_Score=864, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 55318; Mature: 55318

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8200538; 11677609 [H]