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The map label for this gene is dmsC

Identifier: 51595157

GI number: 51595157

Start: 969747

End: 970607

Strand: Direct

Name: dmsC

Synonym: YPTB0807

Alternate gene names: 51595157

Gene position: 969747-970607 (Clockwise)

Preceding gene: 51595156

Following gene: 51595158

Centisome position: 20.44

GC content: 54.12

Gene sequence:

>861_bases
ATGGGCTCAGGATGGCATGAATGGCCACTAATGGTCTTTACCGTACTGGGGCAGTGTGTGGTCGGGGGCTTTATTGTTCT
CGGTCTGGCACTGATATTCGGTGGTTTGAGTCGCGGGCAACAACAGCGGGTTCACCGCAGCATGTTTGTGCTTTGGGTGC
TGATGGCACTGGCTTTTATCGCCTCTACACTGCATTTAGGTTCGCCAATGCGGGCGTTCAACTCATTGAATCGGATCGGT
GAATCTGCACTGAGTAATGAGATTGCCGCCGGTTCGTTGTTCTTTGCTGTGGCCGGTTTTTACTGGTTGTTGGCGGTGTT
GGATAAAATGCCTGCCGCGCTTGGCAAGATCTGGCTGGTGGTGGCAATGGTGCTGGGCGTGATGTTTGTCTACGCCATGT
GCCGGGTCTACTCCATTAATACGGTACCGACGTGGGACAGTATTTATACCCCGCTGGGCTTTGTCCTGACCACGTTGATC
GGTGGCCCGCTATTGGGTTATCTGTTGCTGCAATTGGCTGATGTTAATGGGCGGGCGATGTTACAACTGCCGATGATCAG
CGTATTGGCACTGATCATCAGTGTGGCCAGTGTCATTATGCAGGCGGCCAGTTTGCCGCTGATTTATAGCTCGGTACAGC
AAGCTTCAGCGCTGATCCCCGACTATGGCTCATTGATGGTATGGCGGTTAGTGCTGCTGGTGTTGGGGCTTGGCTGCTGG
ATTTGCCCGTTGATCAGAGGCCGTCGCCCGATGACGCTGGTGATGGTCTTGGGCACGTTACTGGTTATTGCCGGTGAGTT
GATTGGCCGTGGGGTGTTCTACGGGTTACATATGACGGTCGGTATGGCGGTTGGGGGCTAA

Upstream 100 bases:

>100_bases
GCTCACTTCACGCTGCCGAATATCGTACTAAAACCTAATGCCAACAGCCGCCCGGTCAGAGATACCACCGGTCATCTGGC
AAACCCGAAGGAGGTATAAC

Downstream 100 bases:

>100_bases
TCTCCAGACGGCGACGACACTTTGGCTATTCTGGGGAGCGCCCAGAATAGCTTTGCTCTGCCTCATGGCGTGCTAAAACC
AAGGTCATACAGGGCTGAAC

Product: anaerobic dimethyl sulfoxide reductase, subunit C

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase anchor subunit [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIG
ESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVMFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLI
GGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Sequences:

>Translated_286_residues
MGSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIG
ESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVMFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLI
GGPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG
>Mature_285_residues
GSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFIASTLHLGSPMRAFNSLNRIGE
SALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLVVAMVLGVMFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLIG
GPLLGYLLLQLADVNGRAMLQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCWI
CPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds. DmsC anchors the dmsAB dimer to the membrane and stabilizes it [H]

COG id: COG3302

COG function: function code R; DMSO reductase anchor subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli ynfH [H]

Homologues:

Organism=Escherichia coli, GI1787123, Length=285, Percent_Identity=66.3157894736842, Blast_Score=333, Evalue=1e-92,
Organism=Escherichia coli, GI1787873, Length=286, Percent_Identity=59.4405594405594, Blast_Score=314, Evalue=4e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007059 [H]

Pfam domain/function: PF04976 DmsC [H]

EC number: NA

Molecular weight: Translated: 30806; Mature: 30675

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS00962 RIBOSOMAL_S2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GSGWHEWPLMVFTVLGQCVVGGFIVLGLALIFGGLSRGQQQRVHRSMFVLWVLMALAFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ASTLHLGSPMRAFNSLNRIGESALSNEIAAGSLFFAVAGFYWLLAVLDKMPAALGKIWLV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMVLGVMFVYAMCRVYSINTVPTWDSIYTPLGFVLTTLIGGPLLGYLLLQLADVNGRAM
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
LQLPMISVLALIISVASVIMQAASLPLIYSSVQQASALIPDYGSLMVWRLVLLVLGLGCW
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ICPLIRGRRPMTLVMVLGTLLVIAGELIGRGVFYGLHMTVGMAVGG
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 8429002; 2170332 [H]