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The map label for this gene is phnL

Identifier: 51594863

GI number: 51594863

Start: 600943

End: 601662

Strand: Reverse

Name: phnL

Synonym: YPTB0511

Alternate gene names: 51594863

Gene position: 601662-600943 (Counterclockwise)

Preceding gene: 51594864

Following gene: 51594862

Centisome position: 12.68

GC content: 54.44

Gene sequence:

>720_bases
ATGAACCCCCTACAACTCCGGGTTGAAAATATCAGCAAAACCTTCGTGCTCCACCACCAGCACGGTATTCGTCTGCCGGT
ACTGCATCAAATATCACTGGAGGTGAACCGCGGTGAATGTGTCGTGCTACACGGCCATTCCGGGAGTGGAAAATCCACAC
TGCTACGCTCCCTCTATGCCAACTATCTGCCTGACAGCGGCCATATCTGGATCAAACATCAGGGAGAATGGATCGATATC
GTGGCCGCCGAAGCCCGACAAATTATGGCCGTGCGTCACCATACTGTCGGTTGGGTCAGTCAGTTCTTGCGGGTGATCCC
ACGGATTAGTGCATTAAATGTGGTGATGCAGCCCCTATTAGAACTGGGCGTTGATCGGCACACCTGCCAACAACGGGCGC
AGGACCTGCTAACCCGTCTCAATGTCCCGCCACGCTTGTGGGACCTGGCCCCTTCAACGTTTTCTGGCGGCGAACAGCAA
CGGGTTAATATCGCCCGCGGTTTTATTGTGGATTACCCTATCCTGCTGTTGGATGAACCGACCGCATCACTGGACAGCGC
TAACAGCGCAGTCGTGGTCAGCCTGATTGATGAAGCTAAACAACGCGGTGCCGCGATTGTCGGGATTTTCCACGATGAGA
GTGTGCGTAACCATGTCAGTGATCGTTTACTTACCATGACGCCCGCCCCCTCAGAGATCCGCACGGAGATCCCTGTATGA

Upstream 100 bases:

>100_bases
CACTGAAGGCCTATGGATAACCGATGCCTTGGCAAGCGAAACCATTGCACTGAGTGAAATAACCGTACCGAGCGAAACAA
AACATAAACCGAGGCCCACC

Downstream 100 bases:

>100_bases
TCCTCAATAACGTCAGCCTGATTCTTGAAGACAGCGTAGTCAGTGGATCGCTGGAAATCGTAGACGGTGTCATCCGCAGT
TACAGTGATCGCCCGACGCA

Product: ABC phosphonate transporter, ATP binding protein, also C-P lyase component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MNPLQLRVENISKTFVLHHQHGIRLPVLHQISLEVNRGECVVLHGHSGSGKSTLLRSLYANYLPDSGHIWIKHQGEWIDI
VAAEARQIMAVRHHTVGWVSQFLRVIPRISALNVVMQPLLELGVDRHTCQQRAQDLLTRLNVPPRLWDLAPSTFSGGEQQ
RVNIARGFIVDYPILLLDEPTASLDSANSAVVVSLIDEAKQRGAAIVGIFHDESVRNHVSDRLLTMTPAPSEIRTEIPV

Sequences:

>Translated_239_residues
MNPLQLRVENISKTFVLHHQHGIRLPVLHQISLEVNRGECVVLHGHSGSGKSTLLRSLYANYLPDSGHIWIKHQGEWIDI
VAAEARQIMAVRHHTVGWVSQFLRVIPRISALNVVMQPLLELGVDRHTCQQRAQDLLTRLNVPPRLWDLAPSTFSGGEQQ
RVNIARGFIVDYPILLLDEPTASLDSANSAVVVSLIDEAKQRGAAIVGIFHDESVRNHVSDRLLTMTPAPSEIRTEIPV
>Mature_239_residues
MNPLQLRVENISKTFVLHHQHGIRLPVLHQISLEVNRGECVVLHGHSGSGKSTLLRSLYANYLPDSGHIWIKHQGEWIDI
VAAEARQIMAVRHHTVGWVSQFLRVIPRISALNVVMQPLLELGVDRHTCQQRAQDLLTRLNVPPRLWDLAPSTFSGGEQQ
RVNIARGFIVDYPILLLDEPTASLDSANSAVVVSLIDEAKQRGAAIVGIFHDESVRNHVSDRLLTMTPAPSEIRTEIPV

Specific function: Part of the binding-protein-dependent transport system for alkylphosphonates. Probably responsible for energy coupling to the transport system [H]

COG id: COG4778

COG function: function code P; ABC-type phosphonate transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=202, Percent_Identity=30.6930693069307, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI9961250, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790534, Length=221, Percent_Identity=76.0180995475113, Blast_Score=346, Evalue=9e-97,
Organism=Escherichia coli, GI87081834, Length=224, Percent_Identity=32.5892857142857, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788225, Length=226, Percent_Identity=34.5132743362832, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787089, Length=200, Percent_Identity=35, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1787105, Length=215, Percent_Identity=32.093023255814, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787029, Length=199, Percent_Identity=33.6683417085427, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1789873, Length=224, Percent_Identity=29.4642857142857, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789962, Length=204, Percent_Identity=29.9019607843137, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786703, Length=189, Percent_Identity=35.978835978836, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787500, Length=207, Percent_Identity=27.536231884058, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790544, Length=218, Percent_Identity=34.8623853211009, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789672, Length=222, Percent_Identity=30.6306306306306, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI48995001, Length=224, Percent_Identity=28.125, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1786398, Length=217, Percent_Identity=27.6497695852535, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788644, Length=221, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789891, Length=220, Percent_Identity=31.3636363636364, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI48994997, Length=204, Percent_Identity=30.8823529411765, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1787758, Length=203, Percent_Identity=30.0492610837438, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1789991, Length=230, Percent_Identity=29.1304347826087, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788761, Length=233, Percent_Identity=30.4721030042918, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787759, Length=212, Percent_Identity=29.7169811320755, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786872, Length=183, Percent_Identity=28.9617486338798, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87081709, Length=204, Percent_Identity=31.3725490196078, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1789032, Length=242, Percent_Identity=26.4462809917355, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788897, Length=191, Percent_Identity=32.9842931937173, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790467, Length=201, Percent_Identity=29.3532338308458, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788506, Length=195, Percent_Identity=30.2564102564103, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082268, Length=219, Percent_Identity=27.8538812785388, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788472, Length=213, Percent_Identity=27.6995305164319, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI145693107, Length=233, Percent_Identity=27.4678111587983, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790162, Length=217, Percent_Identity=27.6497695852535, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=160, Percent_Identity=33.75, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=211, Percent_Identity=27.9620853080569, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786253, Length=195, Percent_Identity=31.7948717948718, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787792, Length=200, Percent_Identity=29.5, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1786563, Length=228, Percent_Identity=27.1929824561404, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787112, Length=179, Percent_Identity=29.608938547486, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789963, Length=225, Percent_Identity=27.1111111111111, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787370, Length=202, Percent_Identity=31.1881188118812, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787712, Length=194, Percent_Identity=29.8969072164948, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787547, Length=239, Percent_Identity=25.5230125523013, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789593, Length=217, Percent_Identity=27.6497695852535, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI87082267, Length=160, Percent_Identity=28.75, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=197, Percent_Identity=31.9796954314721, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=197, Percent_Identity=31.9796954314721, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR012701 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26696; Mature: 26696

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLQLRVENISKTFVLHHQHGIRLPVLHQISLEVNRGECVVLHGHSGSGKSTLLRSLYA
CCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHH
NYLPDSGHIWIKHQGEWIDIVAAEARQIMAVRHHTVGWVSQFLRVIPRISALNVVMQPLL
HHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELGVDRHTCQQRAQDLLTRLNVPPRLWDLAPSTFSGGEQQRVNIARGFIVDYPILLLDEP
HHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCC
TASLDSANSAVVVSLIDEAKQRGAAIVGIFHDESVRNHVSDRLLTMTPAPSEIRTEIPV
CCCCCCCCCEEEEHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEECCCCHHHHCCCCC
>Mature Secondary Structure
MNPLQLRVENISKTFVLHHQHGIRLPVLHQISLEVNRGECVVLHGHSGSGKSTLLRSLYA
CCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHH
NYLPDSGHIWIKHQGEWIDIVAAEARQIMAVRHHTVGWVSQFLRVIPRISALNVVMQPLL
HHCCCCCEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ELGVDRHTCQQRAQDLLTRLNVPPRLWDLAPSTFSGGEQQRVNIARGFIVDYPILLLDEP
HHCCCHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCC
TASLDSANSAVVVSLIDEAKQRGAAIVGIFHDESVRNHVSDRLLTMTPAPSEIRTEIPV
CCCCCCCCCEEEEHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEECCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]