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The map label for this gene is alr

Identifier: 50843722

GI number: 50843722

Start: 2479808

End: 2480935

Strand: Direct

Name: alr

Synonym: PPA2285

Alternate gene names: 50843722

Gene position: 2479808-2480935 (Clockwise)

Preceding gene: 50843721

Following gene: 50843726

Centisome position: 96.86

GC content: 58.78

Gene sequence:

>1128_bases
ATGCCACGTTGTCCATCGCCTTCTCACGCCATTATTGATCTGTCTGCCATCGCTGCGAACCTCGCCGTCGTGAGGAAACG
CGCAGGCGACCGAAAGGTCCTCTTTGCCGTCAAGGCCGACGCCTATGGGCATGGGGCAGTGGAAGTCTCGCGCTATGTCG
AAAAACACCGGTATGCCGACTGGCTCGCCGTCGCCACGGTCGCTGAAGGCCAAGAGCTGGTTGAAGCCGGCATCACCCTG
CCCATACTCAAACTCTCCCCCGCCGATCCTTGGGACATGGATGCAGCCATTACGTCCGGGATTCGTCTCACCGTGGTGGA
TTTCGACACCCTGGAGGCGGTAAGCAAAGCCGCTGTACGACTAGGAATCACTGCCAAGATTCATATCGCTGTTGATAGCG
GCATGGGACGCATCGGGCTGCGTCCTGAATGCCTTGCTGAACTCACTGCTGCCGCTGACCGCGCCAAAGGCGTCGAAGTC
GAAGGCGTCTTCACTCACCTGCCCATTAGCGATGTGCCGGAGGGGGCGGAGTTCACCCGCCGCGAGATCGACACTTTCAT
GACTGCTGTCTCGCTGATAGAAACACATCGTGGGCCGTTCCCCCTTGTGCACCTGGCCAATTCCGGCGCCATCCTCGGGC
ACGATCTGGGGAAAACCTCCATGGTGCGCGCCGGCATCGTTGGGTACGGATACGATCCCAACCCTCACGCCGACCGTGCC
GACCTACACCCTGCCCTGTCCTGGATCAGCCACGTCACCTTCGTTAAAACTGTCAGTGTGGGGGATACCATCGGCTACGG
CAGAACATGGACAGCCAGCGAAACGACAAAAATCGCCACCGTCCCAGTCGGTTACGCCGACGGACTGTCCCGAGGACTGT
CAAATAAAGGACACGTTCTCATTAGAGGGTCCGTTCATCCCATCGTCGGTCGGATCTGCATGGACCAATTCATGGTCGAT
CTTGGCCCCGATTCGAACGTCACGGTGGGAGATGAGGTGGTGCTCATTGGAACCCAGGAGGACGAAACTCTGACCGCTGA
TGACATGGCCGAACTCCTCGGAACCATTAGCTACGAGATCACTTGCGCCATTTCCAAACGCGTGGATCGGTACTGGGTCG
GGCAGTGA

Upstream 100 bases:

>100_bases
CCAGCCTTTCTCCGAAGCGACCCGACCCTACTCAACCCGGCCCCGCACCGGGCCAACCCGGTGCTTCGCTATTTCTGACA
GTTCACAGGAGTTATGACAC

Downstream 100 bases:

>100_bases
CGAGCCCAAGCTCGTCATCGCGCAATGGCTGGAAGAGAGTATTGCCCAACCTCGTATTACTAAATTCCCCGATTCGGTTG
GGAACCGATCACGTGAGGGC

Product: alanine racemase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPRCPSPSHAIIDLSAIAANLAVVRKRAGDRKVLFAVKADAYGHGAVEVSRYVEKHRYADWLAVATVAEGQELVEAGITL
PILKLSPADPWDMDAAITSGIRLTVVDFDTLEAVSKAAVRLGITAKIHIAVDSGMGRIGLRPECLAELTAAADRAKGVEV
EGVFTHLPISDVPEGAEFTRREIDTFMTAVSLIETHRGPFPLVHLANSGAILGHDLGKTSMVRAGIVGYGYDPNPHADRA
DLHPALSWISHVTFVKTVSVGDTIGYGRTWTASETTKIATVPVGYADGLSRGLSNKGHVLIRGSVHPIVGRICMDQFMVD
LGPDSNVTVGDEVVLIGTQEDETLTADDMAELLGTISYEITCAISKRVDRYWVGQ

Sequences:

>Translated_375_residues
MPRCPSPSHAIIDLSAIAANLAVVRKRAGDRKVLFAVKADAYGHGAVEVSRYVEKHRYADWLAVATVAEGQELVEAGITL
PILKLSPADPWDMDAAITSGIRLTVVDFDTLEAVSKAAVRLGITAKIHIAVDSGMGRIGLRPECLAELTAAADRAKGVEV
EGVFTHLPISDVPEGAEFTRREIDTFMTAVSLIETHRGPFPLVHLANSGAILGHDLGKTSMVRAGIVGYGYDPNPHADRA
DLHPALSWISHVTFVKTVSVGDTIGYGRTWTASETTKIATVPVGYADGLSRGLSNKGHVLIRGSVHPIVGRICMDQFMVD
LGPDSNVTVGDEVVLIGTQEDETLTADDMAELLGTISYEITCAISKRVDRYWVGQ
>Mature_374_residues
PRCPSPSHAIIDLSAIAANLAVVRKRAGDRKVLFAVKADAYGHGAVEVSRYVEKHRYADWLAVATVAEGQELVEAGITLP
ILKLSPADPWDMDAAITSGIRLTVVDFDTLEAVSKAAVRLGITAKIHIAVDSGMGRIGLRPECLAELTAAADRAKGVEVE
GVFTHLPISDVPEGAEFTRREIDTFMTAVSLIETHRGPFPLVHLANSGAILGHDLGKTSMVRAGIVGYGYDPNPHADRAD
LHPALSWISHVTFVKTVSVGDTIGYGRTWTASETTKIATVPVGYADGLSRGLSNKGHVLIRGSVHPIVGRICMDQFMVDL
GPDSNVTVGDEVVLIGTQEDETLTADDMAELLGTISYEITCAISKRVDRYWVGQ

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=368, Percent_Identity=30.7065217391304, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1787439, Length=365, Percent_Identity=30.958904109589, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_PROAC (Q6A5H2)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056949.1
- HSSP:   P0A4X2
- ProteinModelPortal:   Q6A5H2
- GeneID:   2932732
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA2285
- NMPDR:   fig|267747.1.peg.2226
- HOGENOM:   HBG712172
- OMA:   THMASAD
- ProtClustDB:   CLSK2764474
- BioCyc:   PACN267747:PPA2285-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 40140; Mature: 40009

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 38-38 ACT_SITE 266-266

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRCPSPSHAIIDLSAIAANLAVVRKRAGDRKVLFAVKADAYGHGAVEVSRYVEKHRYAD
CCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
WLAVATVAEGQELVEAGITLPILKLSPADPWDMDAAITSGIRLTVVDFDTLEAVSKAAVR
HHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCHHHHCCEEEEEEECHHHHHHHHHHHE
LGITAKIHIAVDSGMGRIGLRPECLAELTAAADRAKGVEVEGVFTHLPISDVPEGAEFTR
ECCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHH
REIDTFMTAVSLIETHRGPFPLVHLANSGAILGHDLGKTSMVRAGIVGYGYDPNPHADRA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCHHHHHCCEEECCCCCCCCCCCH
DLHPALSWISHVTFVKTVSVGDTIGYGRTWTASETTKIATVPVGYADGLSRGLSNKGHVL
HHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEEEEECCCHHHHHHCCCCCCEEE
IRGSVHPIVGRICMDQFMVDLGPDSNVTVGDEVVLIGTQEDETLTADDMAELLGTISYEI
EECCCCHHHHHHHHHHHHHCCCCCCCCEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEE
TCAISKRVDRYWVGQ
EEEEHHCCCHHCCCC
>Mature Secondary Structure 
PRCPSPSHAIIDLSAIAANLAVVRKRAGDRKVLFAVKADAYGHGAVEVSRYVEKHRYAD
CCCCCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
WLAVATVAEGQELVEAGITLPILKLSPADPWDMDAAITSGIRLTVVDFDTLEAVSKAAVR
HHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCCCHHHHCCEEEEEEECHHHHHHHHHHHE
LGITAKIHIAVDSGMGRIGLRPECLAELTAAADRAKGVEVEGVFTHLPISDVPEGAEFTR
ECCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHH
REIDTFMTAVSLIETHRGPFPLVHLANSGAILGHDLGKTSMVRAGIVGYGYDPNPHADRA
HHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCCCCHHHHHCCEEECCCCCCCCCCCH
DLHPALSWISHVTFVKTVSVGDTIGYGRTWTASETTKIATVPVGYADGLSRGLSNKGHVL
HHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEEEEECCCHHHHHHCCCCCCEEE
IRGSVHPIVGRICMDQFMVDLGPDSNVTVGDEVVLIGTQEDETLTADDMAELLGTISYEI
EECCCCHHHHHHHHHHHHHCCCCCCCCEECCEEEEEECCCCCCCCHHHHHHHHHHCCEEE
TCAISKRVDRYWVGQ
EEEEHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA