Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 50843556

GI number: 50843556

Start: 2291788

End: 2292888

Strand: Direct

Name: namA [H]

Synonym: PPA2118

Alternate gene names: 50843556

Gene position: 2291788-2292888 (Clockwise)

Preceding gene: 50843555

Following gene: 50843557

Centisome position: 89.51

GC content: 64.03

Gene sequence:

>1101_bases
ATGACGTCACCGCTCCTGTTCCAACCCCTCACCCTTCGTGGATTGACGGTTCGCAACCGCGCCTGGCTGCCGCCGATGTG
CCAATATGCCGTGGATTCTCAAGACGGAATTCCCAGCACCTGGCACCTCATCCACTATGGATCTTTCGCTGTGGGAGGCT
TCGGCCTCATCGTCGCAGAGGCCACTGCGGTCAGCCCTGAAGGCCGCATCAGCCCTTGTGACACCGGGTTGTGGAATGAC
GCCCAGGTGGCAGCGTGGCGCACCATCACTGACGCTGTCCACGAGCTTGGCGGCACGATTGCTGTCCAGTTGGGCCACGC
CGGCCGGAAAGCCTCCACAGAGAAATGGTGGCCGGGTTTCCATGGCGGGGTGATTCCTCCCGAAAAGGGCGGCTGGATTC
CTGTCGGTCCAACTGCCGCACCCGCCGATGGCAAGCAGTACGCCGGGTCGCCCGTCACCGCCCTTAACGAGGACGGCATC
TCGAAGATTATTGACGACTTCCGGACTGCGGCATCGCGTGCCGTGGTAGCCGGATTCGACGCTGTCGAGATTCATAGCGC
CCACGGCTACTTGCTACATCAGTTTTATTCGCCGCTGTCCAACACCCGCACTGACGGTTGGGGAAGCGATTATGACGGAC
GAGTCCGTCTGCCGTTGGCGGTCGCTGACGCGGTGCGTGGGGCTATTCCCGACGACATGCCTCTGCTGGCCCGCCTCTCG
GTCACTGACTGGCGTGACGATGGCTGGTCAGTCGAGGACTCGATCGAGCTGTCGCGTCGATTCGCCTTGGCTGGCGTCGA
CCTTGTGGATGCCTCCTCAGGTGGTAATTCGTCAGCCCCCATCCCGGTAGCCCCGGGATACCAGGCCGATTTAGCGGCTC
GGGTGCGCGCCGAGGCGGATGTTCCCACCGCCACGGTCGGGATGATCTGGACCGGCGAATTAGCCGAGGATCTACTCAAC
AAGGGGTGTGCCGACGCCGTCATGGTTGGCCGGGCAGCCCTGCGTGACACCAACTGGCCACTGCGCGCCGCCCACGAACT
TGGCGTCCCCAACGAGGAGGCCCCGTGGCACCCGGCGCGATTCCGCGGCGCCTGGCGGTGA

Upstream 100 bases:

>100_bases
GTGACCTCCGTTCGCGAGTGGAAGCCGAATTACCACCATCACGTCTGAGGCCGGCGGCAGCAGAGGGCTCGGGGGTTGAA
ACACGTGATGTTATGGAGTC

Downstream 100 bases:

>100_bases
CAGTCGGTTTCACCACCACGGTCGGCCGCGCGTGGCTGAGAATTAGTTCGTCACGTGACCCCAGGCACACGTATAGTGCT
CGAATCGGCGATGTCGATGA

Product: NADH:flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MTSPLLFQPLTLRGLTVRNRAWLPPMCQYAVDSQDGIPSTWHLIHYGSFAVGGFGLIVAEATAVSPEGRISPCDTGLWND
AQVAAWRTITDAVHELGGTIAVQLGHAGRKASTEKWWPGFHGGVIPPEKGGWIPVGPTAAPADGKQYAGSPVTALNEDGI
SKIIDDFRTAASRAVVAGFDAVEIHSAHGYLLHQFYSPLSNTRTDGWGSDYDGRVRLPLAVADAVRGAIPDDMPLLARLS
VTDWRDDGWSVEDSIELSRRFALAGVDLVDASSGGNSSAPIPVAPGYQADLAARVRAEADVPTATVGMIWTGELAEDLLN
KGCADAVMVGRAALRDTNWPLRAAHELGVPNEEAPWHPARFRGAWR

Sequences:

>Translated_366_residues
MTSPLLFQPLTLRGLTVRNRAWLPPMCQYAVDSQDGIPSTWHLIHYGSFAVGGFGLIVAEATAVSPEGRISPCDTGLWND
AQVAAWRTITDAVHELGGTIAVQLGHAGRKASTEKWWPGFHGGVIPPEKGGWIPVGPTAAPADGKQYAGSPVTALNEDGI
SKIIDDFRTAASRAVVAGFDAVEIHSAHGYLLHQFYSPLSNTRTDGWGSDYDGRVRLPLAVADAVRGAIPDDMPLLARLS
VTDWRDDGWSVEDSIELSRRFALAGVDLVDASSGGNSSAPIPVAPGYQADLAARVRAEADVPTATVGMIWTGELAEDLLN
KGCADAVMVGRAALRDTNWPLRAAHELGVPNEEAPWHPARFRGAWR
>Mature_365_residues
TSPLLFQPLTLRGLTVRNRAWLPPMCQYAVDSQDGIPSTWHLIHYGSFAVGGFGLIVAEATAVSPEGRISPCDTGLWNDA
QVAAWRTITDAVHELGGTIAVQLGHAGRKASTEKWWPGFHGGVIPPEKGGWIPVGPTAAPADGKQYAGSPVTALNEDGIS
KIIDDFRTAASRAVVAGFDAVEIHSAHGYLLHQFYSPLSNTRTDGWGSDYDGRVRLPLAVADAVRGAIPDDMPLLARLSV
TDWRDDGWSVEDSIELSRRFALAGVDLVDASSGGNSSAPIPVAPGYQADLAARVRAEADVPTATVGMIWTGELAEDLLNK
GCADAVMVGRAALRDTNWPLRAAHELGVPNEEAPWHPARFRGAWR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=349, Percent_Identity=33.2378223495702, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789463, Length=355, Percent_Identity=29.8591549295775, Blast_Score=137, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17540738, Length=351, Percent_Identity=25.6410256410256, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17565138, Length=246, Percent_Identity=29.6747967479675, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=288, Percent_Identity=28.125, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=245, Percent_Identity=27.7551020408163, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI72001454, Length=256, Percent_Identity=26.171875, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564188, Length=253, Percent_Identity=26.0869565217391, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=292, Percent_Identity=26.3698630136986, Blast_Score=91, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6325086, Length=240, Percent_Identity=30.8333333333333, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6321973, Length=242, Percent_Identity=31.404958677686, Blast_Score=103, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39094; Mature: 38963

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPLLFQPLTLRGLTVRNRAWLPPMCQYAVDSQDGIPSTWHLIHYGSFAVGGFGLIVAE
CCCCCEECCCEEECEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCHHCCEEEEEEE
ATAVSPEGRISPCDTGLWNDAQVAAWRTITDAVHELGGTIAVQLGHAGRKASTEKWWPGF
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
HGGVIPPEKGGWIPVGPTAAPADGKQYAGSPVTALNEDGISKIIDDFRTAASRAVVAGFD
CCCCCCCCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCC
AVEIHSAHGYLLHQFYSPLSNTRTDGWGSDYDGRVRLPLAVADAVRGAIPDDMPLLARLS
EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEE
VTDWRDDGWSVEDSIELSRRFALAGVDLVDASSGGNSSAPIPVAPGYQADLAARVRAEAD
ECCCCCCCCCCHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
VPTATVGMIWTGELAEDLLNKGCADAVMVGRAALRDTNWPLRAAHELGVPNEEAPWHPAR
CCEEEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHH
FRGAWR
CCCCCC
>Mature Secondary Structure 
TSPLLFQPLTLRGLTVRNRAWLPPMCQYAVDSQDGIPSTWHLIHYGSFAVGGFGLIVAE
CCCCEECCCEEECEEECCCCCCCHHHHHHCCCCCCCCCEEEEEEECCCHHCCEEEEEEE
ATAVSPEGRISPCDTGLWNDAQVAAWRTITDAVHELGGTIAVQLGHAGRKASTEKWWPGF
EEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
HGGVIPPEKGGWIPVGPTAAPADGKQYAGSPVTALNEDGISKIIDDFRTAASRAVVAGFD
CCCCCCCCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCC
AVEIHSAHGYLLHQFYSPLSNTRTDGWGSDYDGRVRLPLAVADAVRGAIPDDMPLLARLS
EEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEE
VTDWRDDGWSVEDSIELSRRFALAGVDLVDASSGGNSSAPIPVAPGYQADLAARVRAEAD
ECCCCCCCCCCHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
VPTATVGMIWTGELAEDLLNKGCADAVMVGRAALRDTNWPLRAAHELGVPNEEAPWHPAR
CCEEEEEEEEEHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCHHH
FRGAWR
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA