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The map label for this gene is 50843512

Identifier: 50843512

GI number: 50843512

Start: 2249642

End: 2250952

Strand: Direct

Name: 50843512

Synonym: PPA2070

Alternate gene names: NA

Gene position: 2249642-2250952 (Clockwise)

Preceding gene: 50843511

Following gene: 50843513

Centisome position: 87.87

GC content: 60.34

Gene sequence:

>1311_bases
ATGGACGAAGCCATGCTGAACTTCGACGAACGCACCGGCCCGAATCAGGGAGTGAACGCCCCGCACTGGCCGTCGGTCCA
GGTGCCTCAATGGTGGAAAGATGCCAAACTCGGATTCTTCATCCACTGGGGCTTGTACTCGGTTCCCGCCTGGGCGACCA
CCAATCCCGACCCGGTACCACTTGAGCAGGAGTACGCCCACCACTGCTACGCCGAGTGGTATGCAAACACGGTGCGCATC
CTCAACTCTCCCACTCGCCGACATCACGACAGGGTATACGGGATCGGAACGAGCTATGAGGACTTCGCCGACTGGTGGAG
CCCCGACCTAGATGCACCTGCCACGCTGATCCGTCGAATTGCTGACGCCGGGGCCGGGTACGTCATCCCGACGACGAAAC
ACCATGACGGATTCTGTCTGTGGCATACCGACACGACCGGCTTCAATGCCGCTAAACGAGGACCGCACCAAGATCTCGTC
AAGGCCTTGCACGACGAGGCGCGAGCGGCAGGACTTAGATTCGGCGTCTACTATTCGGGAGCGCTCGACTGGCATGTTGG
GGACTTCGGGGCGATCACCTCTGATACCGAGCTGTTCACCTTCCGCCGCAACGACCCCGACTTCGCCAAATACTGCGCCG
CTCAACTCACTGAACTTATCGCACGGTTCCGACCAGACATATTGTGGAATGACATTGAGTGGCCCGATGCGGGCAAGGGG
AGTCAGCCCTACGGGCTCGCCAGCCTGTTCAGCCACTACCTGAAGCAAGTACCTGAGGGGGTCGTCAACGACCGCTGGGG
AGTATCCCACCACGGATTCCTCACTCGGGAGTACCGTCATGTTGACGCCAAAATCAACGAACCGTGGGAGTCGACGCGGG
GGCTCGGACGTTCTTTTGGCTACAACCAAGAAGAGTCGACAGACGAGAGCCTTAGTGGCACCGAGCTCGTCCAGTACCTC
GTGGATGTCGTCGCTAAAAACGGAAATCTGCTCATTAACGTCGGGCCACGCGCTGACGGGTCTATTCCTGAGGTGCAGGC
CGCTGCAATGGCCGAACTCGGACGGTGGATGAGGGTGCACGATGAAGCCATTCGGGGTACCCGACCCTGGGGAAACGGGG
TCTACGGTGACCAGCGCATCGTCAAGCGTGGGGAAACTGTCTACGTCCATCTGCTCGACGGGGACGCGCTCCACCTCCCT
GACGAGCTCCAGGGCTTCGATGTCAGCTGGATCGGCAGCCAGAGCAAGCAGACCTCTGTGCCATGCGAGCTCGTTAACCA
GCCGGTCAAGGTCGCGAGGCTCACCCGGTGA

Upstream 100 bases:

>100_bases
ACCCGTTGATCTCCGGGGCTGAATTGCGGGTGCGTCTTGCCTCGCTTAGCGACCGCGCGGTCCTCATAGGCGCAGCCAGT
CTTGGGGTCTGCGACGATCA

Downstream 100 bases:

>100_bases
GGATGGATCCCAGTCATGTAGTAAACACCGACCGCGATAGGACCTCTTAGTTGTGAGGGGGATGGGACCGGCAGAGCTAT
CTCAGTGAAGCGATTCCCGG

Product: alpha-L-fucosidase precursor

Products: L-fucose; alcohol

Alternate protein names: Glycoside Hydrolase Family; Glycosyl Hydrolase; Glycoside Hydrolase Family Alpha-L-Fucosidase; Exported Alpha-L-Fucosidase Protein; Fucosidase; Alpha-L-Fucosidase Protein; Family; Exporte Hydrolase; Alpha-L-Fucosidase Family Protein; Alpha-L-Fucosidase Superfamily; Glycosyl Hydrolase Alpha-L-Fucosidase; Exported Hydrolase; Glycoside Hydrolase

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MDEAMLNFDERTGPNQGVNAPHWPSVQVPQWWKDAKLGFFIHWGLYSVPAWATTNPDPVPLEQEYAHHCYAEWYANTVRI
LNSPTRRHHDRVYGIGTSYEDFADWWSPDLDAPATLIRRIADAGAGYVIPTTKHHDGFCLWHTDTTGFNAAKRGPHQDLV
KALHDEARAAGLRFGVYYSGALDWHVGDFGAITSDTELFTFRRNDPDFAKYCAAQLTELIARFRPDILWNDIEWPDAGKG
SQPYGLASLFSHYLKQVPEGVVNDRWGVSHHGFLTREYRHVDAKINEPWESTRGLGRSFGYNQEESTDESLSGTELVQYL
VDVVAKNGNLLINVGPRADGSIPEVQAAAMAELGRWMRVHDEAIRGTRPWGNGVYGDQRIVKRGETVYVHLLDGDALHLP
DELQGFDVSWIGSQSKQTSVPCELVNQPVKVARLTR

Sequences:

>Translated_436_residues
MDEAMLNFDERTGPNQGVNAPHWPSVQVPQWWKDAKLGFFIHWGLYSVPAWATTNPDPVPLEQEYAHHCYAEWYANTVRI
LNSPTRRHHDRVYGIGTSYEDFADWWSPDLDAPATLIRRIADAGAGYVIPTTKHHDGFCLWHTDTTGFNAAKRGPHQDLV
KALHDEARAAGLRFGVYYSGALDWHVGDFGAITSDTELFTFRRNDPDFAKYCAAQLTELIARFRPDILWNDIEWPDAGKG
SQPYGLASLFSHYLKQVPEGVVNDRWGVSHHGFLTREYRHVDAKINEPWESTRGLGRSFGYNQEESTDESLSGTELVQYL
VDVVAKNGNLLINVGPRADGSIPEVQAAAMAELGRWMRVHDEAIRGTRPWGNGVYGDQRIVKRGETVYVHLLDGDALHLP
DELQGFDVSWIGSQSKQTSVPCELVNQPVKVARLTR
>Mature_436_residues
MDEAMLNFDERTGPNQGVNAPHWPSVQVPQWWKDAKLGFFIHWGLYSVPAWATTNPDPVPLEQEYAHHCYAEWYANTVRI
LNSPTRRHHDRVYGIGTSYEDFADWWSPDLDAPATLIRRIADAGAGYVIPTTKHHDGFCLWHTDTTGFNAAKRGPHQDLV
KALHDEARAAGLRFGVYYSGALDWHVGDFGAITSDTELFTFRRNDPDFAKYCAAQLTELIARFRPDILWNDIEWPDAGKG
SQPYGLASLFSHYLKQVPEGVVNDRWGVSHHGFLTREYRHVDAKINEPWESTRGLGRSFGYNQEESTDESLSGTELVQYL
VDVVAKNGNLLINVGPRADGSIPEVQAAAMAELGRWMRVHDEAIRGTRPWGNGVYGDQRIVKRGETVYVHLLDGDALHLP
DELQGFDVSWIGSQSKQTSVPCELVNQPVKVARLTR

Specific function: Unknown

COG id: COG3669

COG function: function code G; Alpha-L-fucosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40068512, Length=364, Percent_Identity=30.4945054945055, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI119360348, Length=364, Percent_Identity=30.4945054945055, Blast_Score=149, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI71997700, Length=376, Percent_Identity=31.1170212765957, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24662717, Length=394, Percent_Identity=29.4416243654822, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI78706642, Length=394, Percent_Identity=29.4416243654822, Blast_Score=156, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.51

Molecular weight: Translated: 49164; Mature: 49164

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEAMLNFDERTGPNQGVNAPHWPSVQVPQWWKDAKLGFFIHWGLYSVPAWATTNPDPVP
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEECHHCCCCCCCCCCCCCC
LEQEYAHHCYAEWYANTVRILNSPTRRHHDRVYGIGTSYEDFADWWSPDLDAPATLIRRI
CHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHH
ADAGAGYVIPTTKHHDGFCLWHTDTTGFNAAKRGPHQDLVKALHDEARAAGLRFGVYYSG
HHCCCCEEECCCCCCCCEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHCCEEEEEEECC
ALDWHVGDFGAITSDTELFTFRRNDPDFAKYCAAQLTELIARFRPDILWNDIEWPDAGKG
EEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SQPYGLASLFSHYLKQVPEGVVNDRWGVSHHGFLTREYRHVDAKINEPWESTRGLGRSFG
CCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEHHHHCCCCCCCCCHHHHHCCHHHCC
YNQEESTDESLSGTELVQYLVDVVAKNGNLLINVGPRADGSIPEVQAAAMAELGRWMRVH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
DEAIRGTRPWGNGVYGDQRIVKRGETVYVHLLDGDALHLPDELQGFDVSWIGSQSKQTSV
HHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCEECCHHHCCCCEEECCCCCCCCCC
PCELVNQPVKVARLTR
CHHHHCCCHHHHHCCC
>Mature Secondary Structure
MDEAMLNFDERTGPNQGVNAPHWPSVQVPQWWKDAKLGFFIHWGLYSVPAWATTNPDPVP
CCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEECHHCCCCCCCCCCCCCC
LEQEYAHHCYAEWYANTVRILNSPTRRHHDRVYGIGTSYEDFADWWSPDLDAPATLIRRI
CHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCEEECCCCHHHHHHHCCCCCCCHHHHHHHH
ADAGAGYVIPTTKHHDGFCLWHTDTTGFNAAKRGPHQDLVKALHDEARAAGLRFGVYYSG
HHCCCCEEECCCCCCCCEEEEECCCCCCCHHCCCCHHHHHHHHHHHHHHCCEEEEEEECC
ALDWHVGDFGAITSDTELFTFRRNDPDFAKYCAAQLTELIARFRPDILWNDIEWPDAGKG
EEEEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
SQPYGLASLFSHYLKQVPEGVVNDRWGVSHHGFLTREYRHVDAKINEPWESTRGLGRSFG
CCCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCEEHHHHCCCCCCCCCHHHHHCCHHHCC
YNQEESTDESLSGTELVQYLVDVVAKNGNLLINVGPRADGSIPEVQAAAMAELGRWMRVH
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
DEAIRGTRPWGNGVYGDQRIVKRGETVYVHLLDGDALHLPDELQGFDVSWIGSQSKQTSV
HHHHCCCCCCCCCCCCCHHHHHCCCEEEEEEECCCCEECCHHHCCCCEEECCCCCCCCCC
PCELVNQPVKVARLTR
CHHHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; alpha-L-fucoside

Specific reaction: H2O + an alpha-L-fucoside = L-fucose + an alcohol

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA