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The map label for this gene is glcK [H]

Identifier: 50843511

GI number: 50843511

Start: 2248722

End: 2249660

Strand: Direct

Name: glcK [H]

Synonym: PPA2359

Alternate gene names: 50843511

Gene position: 2248722-2249660 (Clockwise)

Preceding gene: 50843510

Following gene: 50843512

Centisome position: 87.83

GC content: 63.79

Gene sequence:

>939_bases
ATGAGCCACCCCGGCGCCTATCGACCGGTCGTCGCCATCGATATTGGCGGCACAACGATGACTATTGCCGAAGTCCGTTC
CGACGGAAGCGTACGAGATCCGGTGACAATGGACAGCCCCGCACGAATCCATGGCGACGAAGTGGTGGCCCGAATATGCG
AGCTTGTCGAGACCCGCTGGCCCCATCCGTGCCGGATCGGCATAGGGACCGCAGGAGTCGTCGACCCTATCAGTGGCTCG
ATCGGCAGAGCATCCGACTCCTTCCAAGGGTGGACCGGGTACCCACTACGCGAACGTCTGGAAGAGGCCCTTGGCGTGGC
GGTCCAAGTGGAAAACGACGTCAATGCCTTCCTCGTTGGCGAGCAACGGTTCGGCGCAGCGGCCGGGGAGCGCGACTGCC
TTGGGATCATGCTTGGTACCGGTGTCGGCGGAGCCGTCATCCTCGACGGACAGGTGATTCATGGTCGGCGCGGGGCCGCA
GCCGAAATCGGTCATATGCCTGCGCTAGGAAACGATCGATGCAGTTGTGGCGTCCCCGGACACCTCGAGTCACTCGCTGG
GGGAAGGGCCATCGCCCGACGCTGGGCTGCGGCCACTGGACGGGATCCCAAATCCGTCAATGGCGCCCGTGAGGTTGCCC
GCCGGGCGGCAAACGGCGATGCTGTGGCGCCGCGAATACTCGCCGAAGCTGGAAAAGCCCTAGGAATCGCACTAGTACAA
GCCGCGACCCTGTTTGATCTGAGTACGGTCATCGTCGGAGGAAGCGTCGCAAGGGCATGGCAGTGGCTCTCGCCCGGCCT
GCACGACGTCGTGACGGCGTACCCGTTGATCTCCGGGGCTGAATTGCGGGTGCGTCTTGCCTCGCTTAGCGACCGCGCGG
TCCTCATAGGCGCAGCCAGTCTTGGGGTCTGCGACGATCAATGGACGAAGCCATGCTGA

Upstream 100 bases:

>100_bases
CATTTGCCACCAACAAGTGCGCCGAAGAACCCCCGTTAGTGGGCGACACTCACCGAGTGGCCTGCCACTTCCCTCTACCA
CACGACGTCTTGGAAGTATC

Downstream 100 bases:

>100_bases
ACTTCGACGAACGCACCGGCCCGAATCAGGGAGTGAACGCCCCGCACTGGCCGTCGGTCCAGGTGCCTCAATGGTGGAAA
GATGCCAAACTCGGATTCTT

Product: putative transcriptional repressor protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSHPGAYRPVVAIDIGGTTMTIAEVRSDGSVRDPVTMDSPARIHGDEVVARICELVETRWPHPCRIGIGTAGVVDPISGS
IGRASDSFQGWTGYPLRERLEEALGVAVQVENDVNAFLVGEQRFGAAAGERDCLGIMLGTGVGGAVILDGQVIHGRRGAA
AEIGHMPALGNDRCSCGVPGHLESLAGGRAIARRWAAATGRDPKSVNGAREVARRAANGDAVAPRILAEAGKALGIALVQ
AATLFDLSTVIVGGSVARAWQWLSPGLHDVVTAYPLISGAELRVRLASLSDRAVLIGAASLGVCDDQWTKPC

Sequences:

>Translated_312_residues
MSHPGAYRPVVAIDIGGTTMTIAEVRSDGSVRDPVTMDSPARIHGDEVVARICELVETRWPHPCRIGIGTAGVVDPISGS
IGRASDSFQGWTGYPLRERLEEALGVAVQVENDVNAFLVGEQRFGAAAGERDCLGIMLGTGVGGAVILDGQVIHGRRGAA
AEIGHMPALGNDRCSCGVPGHLESLAGGRAIARRWAAATGRDPKSVNGAREVARRAANGDAVAPRILAEAGKALGIALVQ
AATLFDLSTVIVGGSVARAWQWLSPGLHDVVTAYPLISGAELRVRLASLSDRAVLIGAASLGVCDDQWTKPC
>Mature_311_residues
SHPGAYRPVVAIDIGGTTMTIAEVRSDGSVRDPVTMDSPARIHGDEVVARICELVETRWPHPCRIGIGTAGVVDPISGSI
GRASDSFQGWTGYPLRERLEEALGVAVQVENDVNAFLVGEQRFGAAAGERDCLGIMLGTGVGGAVILDGQVIHGRRGAAA
EIGHMPALGNDRCSCGVPGHLESLAGGRAIARRWAAATGRDPKSVNGAREVARRAANGDAVAPRILAEAGKALGIALVQA
ATLFDLSTVIVGGSVARAWQWLSPGLHDVVTAYPLISGAELRVRLASLSDRAVLIGAASLGVCDDQWTKPC

Specific function: May Be A Regulator In Specific Sugar Metabolism. May Influence The Rate Of Glucose Uptake Or Glycolysis In Cells In The Rich Medium. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=266, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI190014632, Length=266, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI298566315, Length=266, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4885285, Length=266, Percent_Identity=31.5789473684211, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1787878, Length=268, Percent_Identity=26.1194029850746, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786891, Length=236, Percent_Identity=27.1186440677966, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081733, Length=306, Percent_Identity=25.1633986928105, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787363, Length=307, Percent_Identity=26.7100977198697, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082230, Length=260, Percent_Identity=31.9230769230769, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790522, Length=168, Percent_Identity=35.1190476190476, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082127, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32373; Mature: 32242

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPGAYRPVVAIDIGGTTMTIAEVRSDGSVRDPVTMDSPARIHGDEVVARICELVETRW
CCCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCC
PHPCRIGIGTAGVVDPISGSIGRASDSFQGWTGYPLRERLEEALGVAVQVENDVNAFLVG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEECCCCEEEEE
EQRFGAAAGERDCLGIMLGTGVGGAVILDGQVIHGRRGAAAEIGHMPALGNDRCSCGVPG
CHHHCCCCCCCCEEEEEEECCCCCEEEECCEEEECCCCCCHHHCCCCCCCCCCCCCCCCH
HLESLAGGRAIARRWAAATGRDPKSVNGAREVARRAANGDAVAPRILAEAGKALGIALVQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
AATLFDLSTVIVGGSVARAWQWLSPGLHDVVTAYPLISGAELRVRLASLSDRAVLIGAAS
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECC
LGVCDDQWTKPC
CCCCCCCCCCCC
>Mature Secondary Structure 
SHPGAYRPVVAIDIGGTTMTIAEVRSDGSVRDPVTMDSPARIHGDEVVARICELVETRW
CCCCCCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCC
PHPCRIGIGTAGVVDPISGSIGRASDSFQGWTGYPLRERLEEALGVAVQVENDVNAFLVG
CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEEEEECCCCEEEEE
EQRFGAAAGERDCLGIMLGTGVGGAVILDGQVIHGRRGAAAEIGHMPALGNDRCSCGVPG
CHHHCCCCCCCCEEEEEEECCCCCEEEECCEEEECCCCCCHHHCCCCCCCCCCCCCCCCH
HLESLAGGRAIARRWAAATGRDPKSVNGAREVARRAANGDAVAPRILAEAGKALGIALVQ
HHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHH
AATLFDLSTVIVGGSVARAWQWLSPGLHDVVTAYPLISGAELRVRLASLSDRAVLIGAAS
HHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCEEEEEECC
LGVCDDQWTKPC
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]