Click here to switch to the map view.

The map label for this gene is mntH [H]

Identifier: 50843471

GI number: 50843471

Start: 2198718

End: 2199929

Strand: Reverse

Name: mntH [H]

Synonym: PPA2026

Alternate gene names: 50843471

Gene position: 2199929-2198718 (Counterclockwise)

Preceding gene: 50843476

Following gene: 50843470

Centisome position: 85.93

GC content: 61.63

Gene sequence:

>1212_bases
GTGAGCAACCGAGTGATACGCCTTATGGGGCCAGCTTTCGTCGCCGCCGTGGCGTACGTCGACCCGGGAAACGTCGCCGC
GAACCTGGCAGCCGGAGCCGGCTACGGCTACTTGCTGGTATGGGTGCTCGTCGTCGCCAACGTCGTAGCGATGTTGGTGC
AGTATTTGTCCGCCAAGCTCGGATTGGTTACCGGACATTCCTTGCCCGAACTTGTCGGAGGGGCACTGCCGCGTCGTGGT
AGTCGTCTGGCCTATTGGTTTCAGGCCGAGCTTGTCGCTGCCGCCACTGATCTGGCAGAGGTCATCGGTGGGGCGGTGGC
CCTGCAGCTTCTGTTCGGGCTCCCACTGATCGTAGGTGGACTTATGACCGGGGCGTTGTCGCTGGCGATTTTGGCGATCC
CGTCGCGTCATGGCCAGCGCACCTTCGAGATCGTCATTATCGGGATGCTCGTCGTCATCGCCATCGGGTTCACCGCCGGT
CTTGCTTTTTCCCCGCTGTCATGGGGTGGGGTCGCGTCAGGCCTAGTGCCCCGGTTTGAAGGTACTGAAACCGTCATGCT
CGCCACGTCGATGCTGGGCGCTACAGTCATGCCTCACGCGGTATACATGCACTCTTCCCTGGTGCGTGATCGCCACGGGA
CCGACGACAGGCCAAAACGGATCACCACGCTGTTGCGAGCAACCCGATGGGATGTCGCGGTCTCTCTGGTGCTGGCAGGA
TCGGTGAATATTGCGATGCTGCTGTTGGCTGCGGCGAGCCTGCAAGGTGTTAAGGGTATCGACGGCATAGCTGAGGCTCA
TGCAGCCATGAGTAACTCAATGGGGCCGGTAGTGGGGCTTATTTTCGCGGTGGGGCTGTTCGCGTCAGGTCTGGCTTCAA
CCTCCGTTGGCGCGTATGCCGGAGCTGAGATCATGGCCGGGCTTCTCCATATGAGGGTGCCGATGCTGGTCCGGCGACTT
GTGACGATCATCCCGGCGCTAATCATTCTGGCATCCGGAGCCAATCCGACTCAGGCCCTCGTCTGGAGCCAGGTGCTGTT
GAGCATGGGGTTGCCGCTCGTGTTGGTGCCGTTGGCTCGGTTCACCGGCGATCGGCGGCTGATGGGCCAATGGACGAATG
GGCGTGTCATGGCCGCCATCGCGTGGATCGTCGTGGCAGCAGTCTCGGCTCTCAACGTGGTTCTCGTCGTCGAGACGGTC
ATGGGTGCATGA

Upstream 100 bases:

>100_bases
ATCCTTCCGTCGGTGGATTTCATGACGATTCAGCTCGCCGCCTGACGGGTGACAGTTGTGGCGTTTTGGGGCTCCTTGCC
TGAGGGGACATGATGGCGAT

Downstream 100 bases:

>100_bases
TCCTTGAGGGCAGTTTTCTGGCGACAATCGTGAAAATGAGTGACAAACTCAAGCGGGTGACGACGCCGAACCCCGCACCG
ACCTCTGCCCACGAGCTAGC

Product: manganese transport protein

Products: NA

Alternate protein names: BRAMP [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSNRVIRLMGPAFVAAVAYVDPGNVAANLAAGAGYGYLLVWVLVVANVVAMLVQYLSAKLGLVTGHSLPELVGGALPRRG
SRLAYWFQAELVAAATDLAEVIGGAVALQLLFGLPLIVGGLMTGALSLAILAIPSRHGQRTFEIVIIGMLVVIAIGFTAG
LAFSPLSWGGVASGLVPRFEGTETVMLATSMLGATVMPHAVYMHSSLVRDRHGTDDRPKRITTLLRATRWDVAVSLVLAG
SVNIAMLLLAAASLQGVKGIDGIAEAHAAMSNSMGPVVGLIFAVGLFASGLASTSVGAYAGAEIMAGLLHMRVPMLVRRL
VTIIPALIILASGANPTQALVWSQVLLSMGLPLVLVPLARFTGDRRLMGQWTNGRVMAAIAWIVVAAVSALNVVLVVETV
MGA

Sequences:

>Translated_403_residues
MSNRVIRLMGPAFVAAVAYVDPGNVAANLAAGAGYGYLLVWVLVVANVVAMLVQYLSAKLGLVTGHSLPELVGGALPRRG
SRLAYWFQAELVAAATDLAEVIGGAVALQLLFGLPLIVGGLMTGALSLAILAIPSRHGQRTFEIVIIGMLVVIAIGFTAG
LAFSPLSWGGVASGLVPRFEGTETVMLATSMLGATVMPHAVYMHSSLVRDRHGTDDRPKRITTLLRATRWDVAVSLVLAG
SVNIAMLLLAAASLQGVKGIDGIAEAHAAMSNSMGPVVGLIFAVGLFASGLASTSVGAYAGAEIMAGLLHMRVPMLVRRL
VTIIPALIILASGANPTQALVWSQVLLSMGLPLVLVPLARFTGDRRLMGQWTNGRVMAAIAWIVVAAVSALNVVLVVETV
MGA
>Mature_402_residues
SNRVIRLMGPAFVAAVAYVDPGNVAANLAAGAGYGYLLVWVLVVANVVAMLVQYLSAKLGLVTGHSLPELVGGALPRRGS
RLAYWFQAELVAAATDLAEVIGGAVALQLLFGLPLIVGGLMTGALSLAILAIPSRHGQRTFEIVIIGMLVVIAIGFTAGL
AFSPLSWGGVASGLVPRFEGTETVMLATSMLGATVMPHAVYMHSSLVRDRHGTDDRPKRITTLLRATRWDVAVSLVLAGS
VNIAMLLLAAASLQGVKGIDGIAEAHAAMSNSMGPVVGLIFAVGLFASGLASTSVGAYAGAEIMAGLLHMRVPMLVRRLV
TIIPALIILASGANPTQALVWSQVLLSMGLPLVLVPLARFTGDRRLMGQWTNGRVMAAIAWIVVAAVSALNVVLVVETVM
GA

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=431, Percent_Identity=29.9303944315545, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI295293178, Length=432, Percent_Identity=28.7037037037037, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI295293167, Length=429, Percent_Identity=28.9044289044289, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293171, Length=432, Percent_Identity=28.7037037037037, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293169, Length=432, Percent_Identity=28.7037037037037, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293175, Length=432, Percent_Identity=28.7037037037037, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293173, Length=432, Percent_Identity=28.7037037037037, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI10835169, Length=432, Percent_Identity=28.7037037037037, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1788736, Length=398, Percent_Identity=43.7185929648241, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17569473, Length=401, Percent_Identity=30.6733167082294, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193210616, Length=437, Percent_Identity=29.0617848970252, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI71999499, Length=406, Percent_Identity=29.3103448275862, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71993856, Length=409, Percent_Identity=28.6063569682152, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323062, Length=465, Percent_Identity=30.9677419354839, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324450, Length=418, Percent_Identity=30.622009569378, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6321841, Length=407, Percent_Identity=32.4324324324324, Blast_Score=148, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24648607, Length=435, Percent_Identity=28.5057471264368, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI281362176, Length=435, Percent_Identity=28.5057471264368, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24648609, Length=435, Percent_Identity=28.5057471264368, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI45553443, Length=406, Percent_Identity=28.5714285714286, Blast_Score=148, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025
- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF03358 FMN_red; PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 41749; Mature: 41618

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNRVIRLMGPAFVAAVAYVDPGNVAANLAAGAGYGYLLVWVLVVANVVAMLVQYLSAKL
CCCEEEEECHHHHHHHHEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLVTGHSLPELVGGALPRRGSRLAYWFQAELVAAATDLAEVIGGAVALQLLFGLPLIVGG
HHHCCCCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMTGALSLAILAIPSRHGQRTFEIVIIGMLVVIAIGFTAGLAFSPLSWGGVASGLVPRFE
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
GTETVMLATSMLGATVMPHAVYMHSSLVRDRHGTDDRPKRITTLLRATRWDVAVSLVLAG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
SVNIAMLLLAAASLQGVKGIDGIAEAHAAMSNSMGPVVGLIFAVGLFASGLASTSVGAYA
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHH
GAEIMAGLLHMRVPMLVRRLVTIIPALIILASGANPTQALVWSQVLLSMGLPLVLVPLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
FTGDRRLMGQWTNGRVMAAIAWIVVAAVSALNVVLVVETVMGA
HCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972; 9632246 [H]