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The map label for this gene is ahpC [H]

Identifier: 50843436

GI number: 50843436

Start: 2160476

End: 2161039

Strand: Direct

Name: ahpC [H]

Synonym: PPA1989

Alternate gene names: 50843436

Gene position: 2160476-2161039 (Clockwise)

Preceding gene: 50843433

Following gene: 50843437

Centisome position: 84.38

GC content: 60.46

Gene sequence:

>564_bases
ATGAGTCTCATCAACACCAAGATCCTTCCGTTCAAGGCCAACGCTTTCCGCAACGGGGACTTCATCGAGGTCTCCGATTC
CGACATCAACGGCAAGTGGGCCGTGTTCTTCTTTTACCCCGGTGACTTCACCTTCGTCTGCCCCACCGAGTTGGGCGACC
TCGCCGACCACTATGAGGAACTGCAGGCCATGGGGGTCGAGGTGTTCTCGGTGTCCACCGATTCGCACTTCGTGCACAAG
GCGTGGCATGCCGACTCCGACACCGTCGGCAAGGTGAACTACACGATGATTGGCGATCCGAACCTGCAGCTGACCCGCAA
CTTCGACGTCGAGCGTGAGGGTGCCGGACAGGCTGATCGCGCCACCTTCCTCGTCGACCCTGACGGCGTCATTCAGTTCT
ACGAGCTCACCGCTGAGGGCATTGGGCGTAATGCCACCGAGCTGGTCCGCAAGGTTAAGGCCGCCCAATACATCTACACC
CACCCAGGCGAGGTGTGCCCCGCCAAGTGGGAAGAAGGCGATGAGACCCTCGCCCCGTCGATCGACCTCGTCGGCAAGAT
CTGA

Upstream 100 bases:

>100_bases
CACAGAGAGTCCCGAGTTCATGATCTTTATAGCTATTGACTATAGATGCTGGTTTAGTGATAGCCTTGATCTATCACATC
GTCGACGAGAAAGGACACCC

Downstream 100 bases:

>100_bases
GTTCCGACCCGAGCATCTGCTGCAGGGGCGCTCGTCCCTGCGGCGGATCCCCGGACCGGTACCCTTCCCTCCCCCCTTCA
GGAGAACCATGCTTGATAAT

Product: alkyl hydroperoxide reductase C22 protein

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTKILPFKANAFRNGDFIEVSDSDINGKWAVFFFYPGDFTFVCPTELGDLADHYEELQAMGVEVFSVSTDSHFVHK
AWHADSDTVGKVNYTMIGDPNLQLTRNFDVEREGAGQADRATFLVDPDGVIQFYELTAEGIGRNATELVRKVKAAQYIYT
HPGEVCPAKWEEGDETLAPSIDLVGKI

Sequences:

>Translated_187_residues
MSLINTKILPFKANAFRNGDFIEVSDSDINGKWAVFFFYPGDFTFVCPTELGDLADHYEELQAMGVEVFSVSTDSHFVHK
AWHADSDTVGKVNYTMIGDPNLQLTRNFDVEREGAGQADRATFLVDPDGVIQFYELTAEGIGRNATELVRKVKAAQYIYT
HPGEVCPAKWEEGDETLAPSIDLVGKI
>Mature_186_residues
SLINTKILPFKANAFRNGDFIEVSDSDINGKWAVFFFYPGDFTFVCPTELGDLADHYEELQAMGVEVFSVSTDSHFVHKA
WHADSDTVGKVNYTMIGDPNLQLTRNFDVEREGAGQADRATFLVDPDGVIQFYELTAEGIGRNATELVRKVKAAQYIYTH
PGEVCPAKWEEGDETLAPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=43.3526011560694, Blast_Score=147, Evalue=5e-36,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=43.3526011560694, Blast_Score=147, Evalue=5e-36,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=40, Blast_Score=133, Evalue=7e-32,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=37.7777777777778, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI33188454, Length=73, Percent_Identity=52.0547945205479, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=70.0534759358289, Blast_Score=296, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=40.2298850574713, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=40.2298850574713, Blast_Score=137, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17554494, Length=174, Percent_Identity=39.6551724137931, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25153706, Length=167, Percent_Identity=28.7425149700599, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=34.8571428571429, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=33.7142857142857, Blast_Score=105, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319407, Length=158, Percent_Identity=27.2151898734177, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=37.2881355932203, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=35.6020942408377, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24656348, Length=173, Percent_Identity=37.5722543352601, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17864676, Length=173, Percent_Identity=37.5722543352601, Blast_Score=126, Evalue=6e-30,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=35.2941176470588, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=35.2941176470588, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=31.0126582278481, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24652436, Length=161, Percent_Identity=29.8136645962733, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=29.4871794871795, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20803; Mature: 20672

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTKILPFKANAFRNGDFIEVSDSDINGKWAVFFFYPGDFTFVCPTELGDLADHYEE
CCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LQAMGVEVFSVSTDSHFVHKAWHADSDTVGKVNYTMIGDPNLQLTRNFDVEREGAGQADR
HHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
ATFLVDPDGVIQFYELTAEGIGRNATELVRKVKAAQYIYTHPGEVCPAKWEEGDETLAPS
EEEEECCCCEEEEEEEEHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCC
IDLVGKI
EEEEECC
>Mature Secondary Structure 
SLINTKILPFKANAFRNGDFIEVSDSDINGKWAVFFFYPGDFTFVCPTELGDLADHYEE
CCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
LQAMGVEVFSVSTDSHFVHKAWHADSDTVGKVNYTMIGDPNLQLTRNFDVEREGAGQADR
HHHCCEEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
ATFLVDPDGVIQFYELTAEGIGRNATELVRKVKAAQYIYTHPGEVCPAKWEEGDETLAPS
EEEEECCCCEEEEEEEEHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCC
IDLVGKI
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]