Click here to switch to the map view.

The map label for this gene is sucC

Identifier: 50843215

GI number: 50843215

Start: 1916405

End: 1917580

Strand: Reverse

Name: sucC

Synonym: PPA1755

Alternate gene names: 50843215

Gene position: 1917580-1916405 (Counterclockwise)

Preceding gene: 50843216

Following gene: 50843214

Centisome position: 74.9

GC content: 62.24

Gene sequence:

>1176_bases
GTGGACCTGTATGAATACCAAGCCCGCGACCTGTTTGAGAAGCACGGCGTGCCCGTACTTCGAGGCATCGTCGCGGAGAC
TCCAGAGCAGGCGTCCGAGGCTGCAGCGAAGCTCGGTACCCCCGTCGTCGCCGTCAAGGCGCAGGTCAAAGTGGGTGGCC
GTGGCAAGGCTGGCGGTGTAAAGATCGCTAAGTCCGCGGCCGAGGCGGCTGAACGCGCCGAGGCCATCCTCGGTATGGAC
ATCAAGGGTCACACCGTTCACAAGGTGATGGTCGCTGAAGGTGCTGACATTGCCGAGGAATACTACTTCTCGATCTTGCT
CGACCGTGGAGAGCGTCGCTACCTTGCGATGTGCTCGCGTGAGGGTGGCATGGACATCGAGACCCTTGCTAAGGAGCGCC
CCGAGGCTCTCGCCAAGGTGCCGGTCGACCCGATTGACGGCGTTGACGATGCTAAAGCCCGCGAGATCCTTAGCGAGGCA
GGGTTCCCCGACTCTGAGCAGGACGCTATCGTCCCGGCTGTTCTCAAGCTGTGGGAGACCTACCGTGACGAGGATGCCAC
CCTCGTCGAAGTCAACCCGATGATCAAGACCGGCGATGGACGCATCCTGGCTATCGACGGCAAGATGACTGTTGACAACA
ACGCGTCCTTCCGTCAGCCTGACCATGCCGGCCTGGTGGATCGCGCCACCACCGACCCGCTCGAGTTGCGTGCCGGCGAG
CTCGGTCTCAACTACGTCAAGCTCGACGGCAACGTCGGCGTCATCGGAAACGGTGCTGGACTGGTTATGAGCACCCTTGA
CTGCGTTGCTTACGCCGGTGAGAACTTCCCGGGATCTCCGGCTCCCGCTAACTTCCTCGACATCGGTGGCGGCGCCTCGG
CCGAGATCATGGCCAACGGCCTTGACCTCATCATGAGTGACGAGCAGGTGCGTTCCGTGTTCGTCAACGTCTTTGGCGGT
ATCACCGCCTGTGACCAGGTGGCGCTTGGTATCAAGGGCGCTCTCGAGAAGTTGGGCGACAAGGCCGTGAAGCCGCTCGT
CGTCCGTCTGGACGGCAACGCTGTGGCCGAGGGCCGCAAGATTCTCGAGGAATTCAACTACCCGCTCGTGACCATGGTCT
CGACCATGGACGAGGCCGCCAGCAAGGCCGCCGAGCTCGCATCCAAGGAGGCCTGA

Upstream 100 bases:

>100_bases
GCTTCGCTGTGAACGTTCTTGTGCTGTGAAGTCGAGACAGCTGCCGTCGCCCAGTTCCCCGGCCCGTCAACGGCCGGTCG
ACTCGCAGAGTGGAGAGATT

Downstream 100 bases:

>100_bases
GACATGGCGATCATTCTCGACCAGAACTCCAAAATCATCGTTCAGGGCATGACCGGCTCGGAGGGCATGAAGCACACCCA
GCGCATGCTCGACTCCGGTA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGVKIAKSAAEAAERAEAILGMD
IKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSREGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEA
GFPDSEQDAIVPAVLKLWETYRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGE
LGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANGLDLIMSDEQVRSVFVNVFGG
ITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRKILEEFNYPLVTMVSTMDEAASKAAELASKEA

Sequences:

>Translated_391_residues
MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGVKIAKSAAEAAERAEAILGMD
IKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSREGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEA
GFPDSEQDAIVPAVLKLWETYRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGE
LGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANGLDLIMSDEQVRSVFVNVFGG
ITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRKILEEFNYPLVTMVSTMDEAASKAAELASKEA
>Mature_391_residues
MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGVKIAKSAAEAAERAEAILGMD
IKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSREGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEA
GFPDSEQDAIVPAVLKLWETYRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGE
LGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANGLDLIMSDEQVRSVFVNVFGG
ITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRKILEEFNYPLVTMVSTMDEAASKAAELASKEA

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=401, Percent_Identity=35.9102244389027, Blast_Score=248, Evalue=9e-66,
Organism=Homo sapiens, GI157779135, Length=391, Percent_Identity=36.3171355498721, Blast_Score=243, Evalue=3e-64,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=36.8852459016393, Blast_Score=231, Evalue=6e-61,
Organism=Escherichia coli, GI1786948, Length=396, Percent_Identity=39.1414141414141, Blast_Score=266, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI17539378, Length=399, Percent_Identity=34.8370927318296, Blast_Score=244, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17567829, Length=402, Percent_Identity=36.318407960199, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6321683, Length=405, Percent_Identity=36.2962962962963, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21356231, Length=398, Percent_Identity=35.678391959799, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI161078106, Length=403, Percent_Identity=34.7394540942928, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI24645208, Length=403, Percent_Identity=34.7394540942928, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI281361397, Length=404, Percent_Identity=34.9009900990099, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI281361395, Length=404, Percent_Identity=34.9009900990099, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_PROAC (Q6A6Y0)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056442.1
- HSSP:   P0A836
- ProteinModelPortal:   Q6A6Y0
- SMR:   Q6A6Y0
- GeneID:   2931373
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1755
- NMPDR:   fig|267747.1.peg.1719
- HOGENOM:   HBG315432
- OMA:   IFINILG
- ProtClustDB:   PRK00696
- BioCyc:   PACN267747:PPA1755-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41358; Mature: 41358

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGV
CCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCC
KIAKSAAEAAERAEAILGMDIKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
EGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEAGFPDSEQDAIVPAVLKLWET
CCCCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
YRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGE
HCCCCCEEEEECCCEECCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCHHEEECC
LGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANG
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHCC
LDLIMSDEQVRSVFVNVFGGITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRK
CCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
ILEEFNYPLVTMVSTMDEAASKAAELASKEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLYEYQARDLFEKHGVPVLRGIVAETPEQASEAAAKLGTPVVAVKAQVKVGGRGKAGGV
CCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCC
KIAKSAAEAAERAEAILGMDIKGHTVHKVMVAEGADIAEEYYFSILLDRGERRYLAMCSR
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
EGGMDIETLAKERPEALAKVPVDPIDGVDDAKAREILSEAGFPDSEQDAIVPAVLKLWET
CCCCCHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
YRDEDATLVEVNPMIKTGDGRILAIDGKMTVDNNASFRQPDHAGLVDRATTDPLELRAGE
HCCCCCEEEEECCCEECCCCEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCCHHEEECC
LGLNYVKLDGNVGVIGNGAGLVMSTLDCVAYAGENFPGSPAPANFLDIGGGASAEIMANG
CCCEEEEECCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHCC
LDLIMSDEQVRSVFVNVFGGITACDQVALGIKGALEKLGDKAVKPLVVRLDGNAVAEGRK
CCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHH
ILEEFNYPLVTMVSTMDEAASKAAELASKEA
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA