Click here to switch to the map view.

The map label for this gene is nagZ [H]

Identifier: 50843113

GI number: 50843113

Start: 1793012

End: 1794250

Strand: Direct

Name: nagZ [H]

Synonym: PPA1645

Alternate gene names: 50843113

Gene position: 1793012-1794250 (Clockwise)

Preceding gene: 50843112

Following gene: 50843114

Centisome position: 70.03

GC content: 57.14

Gene sequence:

>1239_bases
ATGAGACGGCGAACAATCATCGCAGCCGGTTTGAGCATGCCGCTTACTGGATGCGTCTCTCAAGATTCCCAGCCCAAGGA
GCCACCGTCCACCACGGTTACGGCATCACCGACTCCTTCTGGCACCTCGACGTCATCCTCGGCAAGCCCGACGTCGGCTC
CATCTCACGCCTCAACGGCTACCTCCAGGCCGACCCCAATCCGCATGAATCCGCGAGCTGTCGAAATCGCCAAGAAATTG
TCTCCCGAGCAACGCGCCGGCCAATGCATTCTTGTCGGCGTAGTGCCATCAGACTCCCCCGAATACATCACCAACCTCAT
TGACACCCAGTGCTTAGCCGGAATCTTCCTGCTAGGACACTGGACGAGCAGGTCCAAGCTTGAGGCCATGCTCAGCGCTG
TTAATCACGTCAGCCCGCAGGGCATCAAACCTATTGTCGCAACTGACCACGAAGGTGGCGAAATCCAGAACATCCGGGTG
CCAGGAGTCGATCACCTGCCGAGTCAGGAAGCTCTGGCCCGGATGTCCCCGGCCAAGGTGCAAGCAGTCGTAACGACCGG
TGCTCGTCAACTCGCCAAACTCGGCGTCCATATGGTCTTCTCCCCCGTGGCTGGCGTCATCGACCCTCGCCTTGGGGTAC
GTAATAAGCCAATTGCCAAGCATCATCGTGGTTTCGGAACCGATCCGCACCTCTGCGGGCAATACTCGGCAGCCGTCGTT
GCGGGACACCGCAAAGCGGGGATCATTTCGACCACTAAGCATTTTCCTGGCATCGGACGGATCACGGAGGATACTGACTT
CAAATCCGCCGGGATTACTGACGACAAGACCACCCGCCACGACCGATATCTTGAGTCTTTCCGGATGGCCTTTGACGCTG
GATCTGAAGCCGTCATGATCGCATCCGCGTACTACTCAAAGATCGATCCCGGCACCCTCGGGTTATTTTCATCAAAGATT
ATGACAGATATGCTGCGCGGAGACTTCGGTTATCAGGGACTCATCGTGTCCGACGACCTGGGGAGTTCAGTCTCAGTATT
CTCAGTCGATGGTGGTCATCGGGCAAGCAAATTCGTCTCTGCCGGCGGCGATCTAGCTATCACAGCTGACCCCCTTCTGG
CAGGCCCCATGATTCGCGCGTTGACGTCGACCGCGACGTCCGCGTCCGGTAAGAAGCGTCTTGTTGACGCTGCTAGCCAT
GTCATCAATGTCAAATTGGCGCATTCATTGACGAAGTGA

Upstream 100 bases:

>100_bases
GACTGTGGCAGCCAGGATCTCGAGGTCTATCTCGTCATACCCGGATGATAGGTCACTGGCATAGTGATGATAGCTGGCCT
ACTGTGAAATACTTCTGCCT

Downstream 100 bases:

>100_bases
GGGGAGAACGAATCATGACTGACGATGGATCCAGCAAAGAGAAGTACCCAGACGATTCACACTCTGGCTACAATGACGCC
GAATTGACCCCCGAGCAGCC

Product: putative beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRRRTIIAAGLSMPLTGCVSQDSQPKEPPSTTVTASPTPSGTSTSSSASPTSAPSHASTATSRPTPIRMNPRAVEIAKKL
SPEQRAGQCILVGVVPSDSPEYITNLIDTQCLAGIFLLGHWTSRSKLEAMLSAVNHVSPQGIKPIVATDHEGGEIQNIRV
PGVDHLPSQEALARMSPAKVQAVVTTGARQLAKLGVHMVFSPVAGVIDPRLGVRNKPIAKHHRGFGTDPHLCGQYSAAVV
AGHRKAGIISTTKHFPGIGRITEDTDFKSAGITDDKTTRHDRYLESFRMAFDAGSEAVMIASAYYSKIDPGTLGLFSSKI
MTDMLRGDFGYQGLIVSDDLGSSVSVFSVDGGHRASKFVSAGGDLAITADPLLAGPMIRALTSTATSASGKKRLVDAASH
VINVKLAHSLTK

Sequences:

>Translated_412_residues
MRRRTIIAAGLSMPLTGCVSQDSQPKEPPSTTVTASPTPSGTSTSSSASPTSAPSHASTATSRPTPIRMNPRAVEIAKKL
SPEQRAGQCILVGVVPSDSPEYITNLIDTQCLAGIFLLGHWTSRSKLEAMLSAVNHVSPQGIKPIVATDHEGGEIQNIRV
PGVDHLPSQEALARMSPAKVQAVVTTGARQLAKLGVHMVFSPVAGVIDPRLGVRNKPIAKHHRGFGTDPHLCGQYSAAVV
AGHRKAGIISTTKHFPGIGRITEDTDFKSAGITDDKTTRHDRYLESFRMAFDAGSEAVMIASAYYSKIDPGTLGLFSSKI
MTDMLRGDFGYQGLIVSDDLGSSVSVFSVDGGHRASKFVSAGGDLAITADPLLAGPMIRALTSTATSASGKKRLVDAASH
VINVKLAHSLTK
>Mature_412_residues
MRRRTIIAAGLSMPLTGCVSQDSQPKEPPSTTVTASPTPSGTSTSSSASPTSAPSHASTATSRPTPIRMNPRAVEIAKKL
SPEQRAGQCILVGVVPSDSPEYITNLIDTQCLAGIFLLGHWTSRSKLEAMLSAVNHVSPQGIKPIVATDHEGGEIQNIRV
PGVDHLPSQEALARMSPAKVQAVVTTGARQLAKLGVHMVFSPVAGVIDPRLGVRNKPIAKHHRGFGTDPHLCGQYSAAVV
AGHRKAGIISTTKHFPGIGRITEDTDFKSAGITDDKTTRHDRYLESFRMAFDAGSEAVMIASAYYSKIDPGTLGLFSSKI
MTDMLRGDFGYQGLIVSDDLGSSVSVFSVDGGHRASKFVSAGGDLAITADPLLAGPMIRALTSTATSASGKKRLVDAASH
VINVKLAHSLTK

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788453, Length=284, Percent_Identity=24.6478873239437, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787350, Length=232, Percent_Identity=25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 43318; Mature: 43318

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRTIIAAGLSMPLTGCVSQDSQPKEPPSTTVTASPTPSGTSTSSSASPTSAPSHASTA
CCCCEEEEECCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TSRPTPIRMNPRAVEIAKKLSPEQRAGQCILVGVVPSDSPEYITNLIDTQCLAGIFLLGH
CCCCCCEEECCHHHHHHHHCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
WTSRSKLEAMLSAVNHVSPQGIKPIVATDHEGGEIQNIRVPGVDHLPSQEALARMSPAKV
CCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHCCCHHE
QAVVTTGARQLAKLGVHMVFSPVAGVIDPRLGVRNKPIAKHHRGFGTDPHLCGQYSAAVV
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHCCCCHHEE
AGHRKAGIISTTKHFPGIGRITEDTDFKSAGITDDKTTRHDRYLESFRMAFDAGSEAVMI
ECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
ASAYYSKIDPGTLGLFSSKIMTDMLRGDFGYQGLIVSDDLGSSVSVFSVDGGHRASKFVS
EEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHH
AGGDLAITADPLLAGPMIRALTSTATSASGKKRLVDAASHVINVKLAHSLTK
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEHHHHCCC
>Mature Secondary Structure
MRRRTIIAAGLSMPLTGCVSQDSQPKEPPSTTVTASPTPSGTSTSSSASPTSAPSHASTA
CCCCEEEEECCCCCCHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCC
TSRPTPIRMNPRAVEIAKKLSPEQRAGQCILVGVVPSDSPEYITNLIDTQCLAGIFLLGH
CCCCCCEEECCHHHHHHHHCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHC
WTSRSKLEAMLSAVNHVSPQGIKPIVATDHEGGEIQNIRVPGVDHLPSQEALARMSPAKV
CCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCEEEEECCCCCCCCCHHHHHHCCCHHE
QAVVTTGARQLAKLGVHMVFSPVAGVIDPRLGVRNKPIAKHHRGFGTDPHLCGQYSAAVV
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCHHCCCCHHEE
AGHRKAGIISTTKHFPGIGRITEDTDFKSAGITDDKTTRHDRYLESFRMAFDAGSEAVMI
ECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEE
ASAYYSKIDPGTLGLFSSKIMTDMLRGDFGYQGLIVSDDLGSSVSVFSVDGGHRASKFVS
EEHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCHHHHHHH
AGGDLAITADPLLAGPMIRALTSTATSASGKKRLVDAASHVINVKLAHSLTK
CCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA