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The map label for this gene is clpX

Identifier: 50843045

GI number: 50843045

Start: 1697985

End: 1699274

Strand: Reverse

Name: clpX

Synonym: PPA1571

Alternate gene names: 50843045

Gene position: 1699274-1697985 (Counterclockwise)

Preceding gene: 50843046

Following gene: 50843044

Centisome position: 66.37

GC content: 58.45

Gene sequence:

>1290_bases
ATGGCGCGAATTGGTGAGAGCGGAGACCTGTTCAAATGTTCCTTTTGCGGTAAGAGTCAGAAGCAGGTCAAGAAGCTCAT
CGCTGGCCCCGGGGTCTACATCTGTGACGAATGTATTGAGCTGTGCAACGAGATCATCGAGGAGGAGTTTTCGTCCTCCG
ACGAGGCCGGTGGGGTCGAGGACCTTCCCCGTCCGCGCGAGTTGTGTGAATTCCTTGACGCTTGGGTGATCGGTCAGGAA
GAGGCCAAGCGGACCCTCTCGGTGGCTGTCTACAACCATTACAAGCGCATCCAGTCCGAGGCCAATGTGCCGCGTGCCCG
TCGCGCCGAGGACGATGGGGTGGAGCTCGGTAAGTCGAATATCCTCATGCTTGGGCCGACTGGCTGCGGCAAAACTTACC
TAGCTCAGACGATGGCTCGTCAGCTCAACGTCCCCTTCGCAATGGCTGACGCCACCGCTCTTACTGAAGCTGGTTACGTC
GGTGAAGACGTCGAGAATATCCTGCTCAAACTGCTGCAGGCGGCTGACTTCGACGTCAAGCGGGCTGAGCGGGGAATCGT
CTATATTGACGAGATTGACAAAGTGGCTCGCAAAGCGGAGAACCCGTCAATCACTCGCGACGTCTCCGGTGAGGGCGTTC
AGCAGGCCCTGCTCAAGATTCTTGAGGGAACAGTGGCCTCAGTGCCTCCCCAAGGTGGACGCAAACATCCTCAACAGGAC
TTCATCCAGATCGATACCACCAACGTCCTGTTCATCGTGGGGGGCGCCTTCGCCGGTCTGGAAGACATCATCGCCAAGCG
GATCGGTACTCGTCCGTTGGGATTCAACAATGATCCGGGTGCGAGCGAGGTCATTGAGGGGCCCGAAGCCCTCAGTCTGG
TGCGCCCAGAGGACCTTCACCAGTTTGGGCTTATTCCAGAGTTCATCGGACGTCTGCCAATGGTTACGGCTGTGCACCCG
CTCGACCGCAAAGCCCTGGTTCGCATTCTGACCGAGCCTCGCAATGCTCTGACCCGCCAATTTGAGAAACTCTTCGAGTT
GGACGGGGTGGAATTGACCTTTACCGAGGGAGCTCTGGGGGCGATCGCCGACAAGGCTGTTGCACGAGGGACCGGTGCAC
GCGGACTGCGGGCCATTATTGAGGAGACCCTCATGGACGTCATGTTCGACGTCCCCTCCCGCGATGATGTCTCCCGAGTC
GTGGTAACCCAGGAAGCCATCACCGGTGAAGGGAAGTGTCAGTACCTCTCCACGCCGGTCTTTCATGGTCGAGGCAGGCT
ATCTGCCTGA

Upstream 100 bases:

>100_bases
GATACTGTCCATAACTAAGGTGTACGGCGCACACCTCGGGAGGACGATCGTCGCGGAGAAGACGGATCGACACGAGTATG
CCGAGTAGGAGGGAAGCCGG

Downstream 100 bases:

>100_bases
GGTTAGTGCTCGTCAAGGACCTCGACGAGCAGTTTGTCAGCCCGCTTCTGCAAGGTCGCCATGGACTTGCGGGCCTTCGC
GTATCTGCCTTCGCGCCTCC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MARIGESGDLFKCSFCGKSQKQVKKLIAGPGVYICDECIELCNEIIEEEFSSSDEAGGVEDLPRPRELCEFLDAWVIGQE
EAKRTLSVAVYNHYKRIQSEANVPRARRAEDDGVELGKSNILMLGPTGCGKTYLAQTMARQLNVPFAMADATALTEAGYV
GEDVENILLKLLQAADFDVKRAERGIVYIDEIDKVARKAENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQD
FIQIDTTNVLFIVGGAFAGLEDIIAKRIGTRPLGFNNDPGASEVIEGPEALSLVRPEDLHQFGLIPEFIGRLPMVTAVHP
LDRKALVRILTEPRNALTRQFEKLFELDGVELTFTEGALGAIADKAVARGTGARGLRAIIEETLMDVMFDVPSRDDVSRV
VVTQEAITGEGKCQYLSTPVFHGRGRLSA

Sequences:

>Translated_429_residues
MARIGESGDLFKCSFCGKSQKQVKKLIAGPGVYICDECIELCNEIIEEEFSSSDEAGGVEDLPRPRELCEFLDAWVIGQE
EAKRTLSVAVYNHYKRIQSEANVPRARRAEDDGVELGKSNILMLGPTGCGKTYLAQTMARQLNVPFAMADATALTEAGYV
GEDVENILLKLLQAADFDVKRAERGIVYIDEIDKVARKAENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQD
FIQIDTTNVLFIVGGAFAGLEDIIAKRIGTRPLGFNNDPGASEVIEGPEALSLVRPEDLHQFGLIPEFIGRLPMVTAVHP
LDRKALVRILTEPRNALTRQFEKLFELDGVELTFTEGALGAIADKAVARGTGARGLRAIIEETLMDVMFDVPSRDDVSRV
VVTQEAITGEGKCQYLSTPVFHGRGRLSA
>Mature_428_residues
ARIGESGDLFKCSFCGKSQKQVKKLIAGPGVYICDECIELCNEIIEEEFSSSDEAGGVEDLPRPRELCEFLDAWVIGQEE
AKRTLSVAVYNHYKRIQSEANVPRARRAEDDGVELGKSNILMLGPTGCGKTYLAQTMARQLNVPFAMADATALTEAGYVG
EDVENILLKLLQAADFDVKRAERGIVYIDEIDKVARKAENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQDF
IQIDTTNVLFIVGGAFAGLEDIIAKRIGTRPLGFNNDPGASEVIEGPEALSLVRPEDLHQFGLIPEFIGRLPMVTAVHPL
DRKALVRILTEPRNALTRQFEKLFELDGVELTFTEGALGAIADKAVARGTGARGLRAIIEETLMDVMFDVPSRDDVSRVV
VTQEAITGEGKCQYLSTPVFHGRGRLSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=510, Percent_Identity=39.2156862745098, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1786642, Length=408, Percent_Identity=60.7843137254902, Blast_Score=503, Evalue=1e-144,
Organism=Escherichia coli, GI1790366, Length=111, Percent_Identity=40.5405405405405, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982908, Length=324, Percent_Identity=46.2962962962963, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=324, Percent_Identity=46.2962962962963, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=38.8324873096447, Blast_Score=250, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=252, Percent_Identity=38.8888888888889, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=412, Percent_Identity=40.5339805825243, Blast_Score=282, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24648291, Length=319, Percent_Identity=47.6489028213166, Blast_Score=287, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24648289, Length=319, Percent_Identity=47.6489028213166, Blast_Score=287, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PROAC (Q6A7F1)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056272.1
- ProteinModelPortal:   Q6A7F1
- GeneID:   2931098
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1571
- NMPDR:   fig|267747.1.peg.1549
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- BioCyc:   PACN267747:PPA1571-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46769; Mature: 46638

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARIGESGDLFKCSFCGKSQKQVKKLIAGPGVYICDECIELCNEIIEEEFSSSDEAGGVE
CCCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLPRPRELCEFLDAWVIGQEEAKRTLSVAVYNHYKRIQSEANVPRARRAEDDGVELGKSN
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCC
ILMLGPTGCGKTYLAQTMARQLNVPFAMADATALTEAGYVGEDVENILLKLLQAADFDVK
EEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAERGIVYIDEIDKVARKAENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQD
HHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHH
FIQIDTTNVLFIVGGAFAGLEDIIAKRIGTRPLGFNNDPGASEVIEGPEALSLVRPEDLH
CEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHCCCCHHHH
QFGLIPEFIGRLPMVTAVHPLDRKALVRILTEPRNALTRQFEKLFELDGVELTFTEGALG
HHCCCHHHHCCCCCCHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCCCHH
AIADKAVARGTGARGLRAIIEETLMDVMFDVPSRDDVSRVVVTQEAITGEGKCQYLSTPV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHCCCCCEEEECCCC
FHGRGRLSA
CCCCCCCCC
>Mature Secondary Structure 
ARIGESGDLFKCSFCGKSQKQVKKLIAGPGVYICDECIELCNEIIEEEFSSSDEAGGVE
CCCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DLPRPRELCEFLDAWVIGQEEAKRTLSVAVYNHYKRIQSEANVPRARRAEDDGVELGKSN
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCC
ILMLGPTGCGKTYLAQTMARQLNVPFAMADATALTEAGYVGEDVENILLKLLQAADFDVK
EEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHH
RAERGIVYIDEIDKVARKAENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPQQD
HHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHH
FIQIDTTNVLFIVGGAFAGLEDIIAKRIGTRPLGFNNDPGASEVIEGPEALSLVRPEDLH
CEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHCCCCHHHH
QFGLIPEFIGRLPMVTAVHPLDRKALVRILTEPRNALTRQFEKLFELDGVELTFTEGALG
HHCCCHHHHCCCCCCHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEECCCCHH
AIADKAVARGTGARGLRAIIEETLMDVMFDVPSRDDVSRVVVTQEAITGEGKCQYLSTPV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHHCCCCCEEEECCCC
FHGRGRLSA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA