| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is hppA
Identifier: 50843031
GI number: 50843031
Start: 1674674
End: 1677157
Strand: Direct
Name: hppA
Synonym: PPA1556
Alternate gene names: 50843031
Gene position: 1674674-1677157 (Clockwise)
Preceding gene: 50843030
Following gene: 50843032
Centisome position: 65.41
GC content: 58.05
Gene sequence:
>2484_bases ATGAAGCGCCTACGTGGCTGCGCACTGCCCATACTTCTTACCACCCTCGCCCTAGCTGGATGCAGTTCCGGCAGGCAGAC CAAGGGAGGAGGTGGCGGTGAGGCCAATCTGAAGCTGCCTCCTCTCAATGAGCACGTCGGAAACGTCTCCGGGACTGCCC TGCTGTGGATCGGACTGGTGATCTGCCTGTTCGGTTTGGGATTCGGTCTGGTGACGTATTCCAAGCTGGAAAAGTTACCC GTCCACGAGGCGATGCATGAGGTTTCCGAACTCATCTACGAAACCTGTAAGACCTACCTTAAGCAACAGGCCAAGTTCCT CATGCTGCTGTGGGCTTTCATCGCTGCGATTATCGTCGTGTACTTCCTGCTCCTCGAACACATGGGCGCCAAGGTGCTCA TCATCTTGCTGTTTAGCCTTGTCGGGATGGCAGGATCTTTCGGAGTCGCCTGGTATGGCATTCGCGTCAACACTTTCGCG AACTCCCGTACCGCCCATGCGTCACTGCGCGGTTCCCCATGGGCGACCTTCGACATTCCCATGCGTTCTGGCATGAGCAT CGGCATGGTCCTCATCAGCGTCGAGTTGACCCTCATGCTCTTCATCATGCTGGTGTTACCCGGCGATCTCGCTGGCCCGT GCTTCATCGGATTCGCCATCGGCGAGTCCCTCGGCGCTGCCTGTCTACGTATCGCTGGCGGTATCTTCACCAAGATCGCT GACGTCGGCGCCGACCTTATGAAGATCGCCTTCCACATCAAGGAAGATGACGCCCGTAACCCGGGTGTCATCGCTGACTG CACCGGTGACAATGCCGGCGACTCAGTCGGCCCGTCCGCTGATGGATTTGAGACCTACGGCGTCACTGGCGTAGCCCTCA TCACCTTCGTGCTGGGAGCCGTTCCGGATCAGACGGAGCAGGTCCAATTGCTGGTGTGGATCTTCGTCGTCCGCGTGGTC ATGCTCATCGCGTCCTTCGTGTCTTACCTCATCAACAACGCCGTCGCGAAAGCCCGCTACGGCACGGTCTCGGAGATGGA CTTCGAGAAGCCGCTGAGTTCCCTGGTGTGGATTACCTCGGTGATGTCGATCCTGCTAACTGTCCTGACCACCCGGTGGA TGCTCGGTTCAATGGGAGACGGAACGATGTGGTGGAAGCTGTCCATCATCATCTCCTGTGGCACCTTGGCCGGTGCCCTC ATTCCGGAGCTCGTCAAGGCCTTCACCTCAACGAATTCTCGTCACGTGCGTGAGGTCGTGACGAGTGCCCGAGAGGGAGG CGCTTCCTTGGACATCTTATCTGGCCTGGTCGCCGGTAACTTCTCCGGATTCTGGTTGGGCATCATCATCGTCGCCCTCA TGGGCGCATCCTTCCTCGTCTCGGGCACCGGTTCGGGCCTGGGCGATATGGGAACTATGAGCGAAGTCAAATGGGCAGTC TTCGCTTTCGGTCTCGTCGCCTTTGGCTTCCTCGGCATGGGTGCGGTGACGATCGCTGTCGACTCTTACGGTCCGGTGAC CGATAACGCCCAGAGCGTCTACGAGCTGTCGACTATCGAAGATATCCCGAACGTCTCCGACGAGTTCGAGAAGCACTATG GATTCGCCCCCAGGTGGGACATCGCCAAGCGCATCTTGGAAGCTCAGGACGGCGCTGGTAACACCTTCAAAGCCACTGCC AAACCGGTGCTCATCGGTACTGCCGTCGTCGGCGCGACCACGATGATCTTCTCGATCATCATGATGCTCACTGAGGGCCT ATCGAACGCTGCTGAGGTCAACAAGTTAGGCCTGGCCCACGCCCCATTCCTGCTCGGCCTCATCACCGGCGGCGCCGTCA TCTACTGGTTCTCCGGAGCCTCGATGCAGGCTGTCACGACCGGCGCTTACCGGGCCGTCGAGTTCATCAAGAACAATATG CAGCTCGATCAGAACGCCACCAAGGCCTCCAGTAAAGACTCCAAGAAGGTCGTCCAGATCTGCACCGAGTATGCCCAGAA GGGCATGCTTAACATCTTCCTGGGTGTGTTCTTCGCAGCCCTCGGGTTCGCTTTCGTCGATCCGTACTTCTTCATCGGGT ACCTGATCTCGATTGCCATCTTCGGCCTTTACCAAGCCATCTTCATGGCCAACGCTGGTGGCGCTTGGGACAACGCAAAG AAGATCGTTGAGGTGGACCTGGATGCCAAAGGCACTGAGCTGCATGACGCTTCGGTGGTTGGTGATACCGTTGGCGACCC ATTCAAGGACACCTCATCGGTGGCCCTTAACCCGGTCATTAAGTTTACGACTCTCTTCGGCCTGCTAGCTGTGGAGTTGG CAGTGTCGATTGGTGTCGGTTTGCTGACCTACATCCTTGCCGCGGTGTTCATCCTCGTCGCTTGCGTCTTCGTCTACCGT TCCTTCTACGGCATGCGAATTGACTCGACGAAGGATCCTGAAGAGTTCGGCGTCGTCGCTAAGGAGGCTGGCAGCGGGTC GTGA
Upstream 100 bases:
>100_bases ACGTCATACGGTTAGAAGTAAGGCCTGCACGGATGCAGGTGCACGAGAGCTCTCAGGAGAGAGACAGCATCGTGAACACG GTTGACAAGGGGGTTTCCCC
Downstream 100 bases:
>100_bases TTGGCAGAAGGGTTCTACACTGGCCGTCGTGCCGGAAACCCCTTTGACTCTGGACCCTCACGCTCCAACAGAAGTCCTGC TTCTCGAGGACGTGAGGGTC
Product: membrane-bound proton-translocating pyrophosphatase
Products: NA
Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]
Number of amino acids: Translated: 827; Mature: 827
Protein sequence:
>827_residues MKRLRGCALPILLTTLALAGCSSGRQTKGGGGGEANLKLPPLNEHVGNVSGTALLWIGLVICLFGLGFGLVTYSKLEKLP VHEAMHEVSELIYETCKTYLKQQAKFLMLLWAFIAAIIVVYFLLLEHMGAKVLIILLFSLVGMAGSFGVAWYGIRVNTFA NSRTAHASLRGSPWATFDIPMRSGMSIGMVLISVELTLMLFIMLVLPGDLAGPCFIGFAIGESLGAACLRIAGGIFTKIA DVGADLMKIAFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFVLGAVPDQTEQVQLLVWIFVVRVV MLIASFVSYLINNAVAKARYGTVSEMDFEKPLSSLVWITSVMSILLTVLTTRWMLGSMGDGTMWWKLSIIISCGTLAGAL IPELVKAFTSTNSRHVREVVTSAREGGASLDILSGLVAGNFSGFWLGIIIVALMGASFLVSGTGSGLGDMGTMSEVKWAV FAFGLVAFGFLGMGAVTIAVDSYGPVTDNAQSVYELSTIEDIPNVSDEFEKHYGFAPRWDIAKRILEAQDGAGNTFKATA KPVLIGTAVVGATTMIFSIIMMLTEGLSNAAEVNKLGLAHAPFLLGLITGGAVIYWFSGASMQAVTTGAYRAVEFIKNNM QLDQNATKASSKDSKKVVQICTEYAQKGMLNIFLGVFFAALGFAFVDPYFFIGYLISIAIFGLYQAIFMANAGGAWDNAK KIVEVDLDAKGTELHDASVVGDTVGDPFKDTSSVALNPVIKFTTLFGLLAVELAVSIGVGLLTYILAAVFILVACVFVYR SFYGMRIDSTKDPEEFGVVAKEAGSGS
Sequences:
>Translated_827_residues MKRLRGCALPILLTTLALAGCSSGRQTKGGGGGEANLKLPPLNEHVGNVSGTALLWIGLVICLFGLGFGLVTYSKLEKLP VHEAMHEVSELIYETCKTYLKQQAKFLMLLWAFIAAIIVVYFLLLEHMGAKVLIILLFSLVGMAGSFGVAWYGIRVNTFA NSRTAHASLRGSPWATFDIPMRSGMSIGMVLISVELTLMLFIMLVLPGDLAGPCFIGFAIGESLGAACLRIAGGIFTKIA DVGADLMKIAFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFVLGAVPDQTEQVQLLVWIFVVRVV MLIASFVSYLINNAVAKARYGTVSEMDFEKPLSSLVWITSVMSILLTVLTTRWMLGSMGDGTMWWKLSIIISCGTLAGAL IPELVKAFTSTNSRHVREVVTSAREGGASLDILSGLVAGNFSGFWLGIIIVALMGASFLVSGTGSGLGDMGTMSEVKWAV FAFGLVAFGFLGMGAVTIAVDSYGPVTDNAQSVYELSTIEDIPNVSDEFEKHYGFAPRWDIAKRILEAQDGAGNTFKATA KPVLIGTAVVGATTMIFSIIMMLTEGLSNAAEVNKLGLAHAPFLLGLITGGAVIYWFSGASMQAVTTGAYRAVEFIKNNM QLDQNATKASSKDSKKVVQICTEYAQKGMLNIFLGVFFAALGFAFVDPYFFIGYLISIAIFGLYQAIFMANAGGAWDNAK KIVEVDLDAKGTELHDASVVGDTVGDPFKDTSSVALNPVIKFTTLFGLLAVELAVSIGVGLLTYILAAVFILVACVFVYR SFYGMRIDSTKDPEEFGVVAKEAGSGS >Mature_827_residues MKRLRGCALPILLTTLALAGCSSGRQTKGGGGGEANLKLPPLNEHVGNVSGTALLWIGLVICLFGLGFGLVTYSKLEKLP VHEAMHEVSELIYETCKTYLKQQAKFLMLLWAFIAAIIVVYFLLLEHMGAKVLIILLFSLVGMAGSFGVAWYGIRVNTFA NSRTAHASLRGSPWATFDIPMRSGMSIGMVLISVELTLMLFIMLVLPGDLAGPCFIGFAIGESLGAACLRIAGGIFTKIA DVGADLMKIAFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFVLGAVPDQTEQVQLLVWIFVVRVV MLIASFVSYLINNAVAKARYGTVSEMDFEKPLSSLVWITSVMSILLTVLTTRWMLGSMGDGTMWWKLSIIISCGTLAGAL IPELVKAFTSTNSRHVREVVTSAREGGASLDILSGLVAGNFSGFWLGIIIVALMGASFLVSGTGSGLGDMGTMSEVKWAV FAFGLVAFGFLGMGAVTIAVDSYGPVTDNAQSVYELSTIEDIPNVSDEFEKHYGFAPRWDIAKRILEAQDGAGNTFKATA KPVLIGTAVVGATTMIFSIIMMLTEGLSNAAEVNKLGLAHAPFLLGLITGGAVIYWFSGASMQAVTTGAYRAVEFIKNNM QLDQNATKASSKDSKKVVQICTEYAQKGMLNIFLGVFFAALGFAFVDPYFFIGYLISIAIFGLYQAIFMANAGGAWDNAK KIVEVDLDAKGTELHDASVVGDTVGDPFKDTSSVALNPVIKFTTLFGLLAVELAVSIGVGLLTYILAAVFILVACVFVYR SFYGMRIDSTKDPEEFGVVAKEAGSGS
Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]
COG id: COG3808
COG function: function code C; Inorganic pyrophosphatase
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004131 [H]
Pfam domain/function: PF03030 H_PPase [H]
EC number: =3.6.1.1 [H]
Molecular weight: Translated: 87977; Mature: 87977
Theoretical pI: Translated: 5.39; Mature: 5.39
Prosite motif: PS00013 PROKAR_LIPOPROTEIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 4.7 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 4.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRLRGCALPILLTTLALAGCSSGRQTKGGGGGEANLKLPPLNEHVGNVSGTALLWIGLV CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCHHHHHHHHHH ICLFGLGFGLVTYSKLEKLPVHEAMHEVSELIYETCKTYLKQQAKFLMLLWAFIAAIIVV HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YFLLLEHMGAKVLIILLFSLVGMAGSFGVAWYGIRVNTFANSRTAHASLRGSPWATFDIP HHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEECC MRSGMSIGMVLISVELTLMLFIMLVLPGDLAGPCFIGFAIGESLGAACLRIAGGIFTKIA CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH DVGADLMKIAFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFVLGA HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHC VPDQTEQVQLLVWIFVVRVVMLIASFVSYLINNAVAKARYGTVSEMDFEKPLSSLVWITS CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH VMSILLTVLTTRWMLGSMGDGTMWWKLSIIISCGTLAGALIPELVKAFTSTNSRHVREVV HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH TSAREGGASLDILSGLVAGNFSGFWLGIIIVALMGASFLVSGTGSGLGDMGTMSEVKWAV HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEECCCCCCCCCCCHHHHHHHH FAFGLVAFGFLGMGAVTIAVDSYGPVTDNAQSVYELSTIEDIPNVSDEFEKHYGFAPRWD HHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHH IAKRILEAQDGAGNTFKATAKPVLIGTAVVGATTMIFSIIMMLTEGLSNAAEVNKLGLAH HHHHHHHHCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHH APFLLGLITGGAVIYWFSGASMQAVTTGAYRAVEFIKNNMQLDQNATKASSKDSKKVVQI HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHH CTEYAQKGMLNIFLGVFFAALGFAFVDPYFFIGYLISIAIFGLYQAIFMANAGGAWDNAK HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC KIVEVDLDAKGTELHDASVVGDTVGDPFKDTSSVALNPVIKFTTLFGLLAVELAVSIGVG EEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH LLTYILAAVFILVACVFVYRSFYGMRIDSTKDPEEFGVVAKEAGSGS HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHCCCCCCC >Mature Secondary Structure MKRLRGCALPILLTTLALAGCSSGRQTKGGGGGEANLKLPPLNEHVGNVSGTALLWIGLV CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCHHHHCCCCHHHHHHHHHH ICLFGLGFGLVTYSKLEKLPVHEAMHEVSELIYETCKTYLKQQAKFLMLLWAFIAAIIVV HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YFLLLEHMGAKVLIILLFSLVGMAGSFGVAWYGIRVNTFANSRTAHASLRGSPWATFDIP HHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCEEEECC MRSGMSIGMVLISVELTLMLFIMLVLPGDLAGPCFIGFAIGESLGAACLRIAGGIFTKIA CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH DVGADLMKIAFHIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFVLGA HHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHC VPDQTEQVQLLVWIFVVRVVMLIASFVSYLINNAVAKARYGTVSEMDFEKPLSSLVWITS CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH VMSILLTVLTTRWMLGSMGDGTMWWKLSIIISCGTLAGALIPELVKAFTSTNSRHVREVV HHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH TSAREGGASLDILSGLVAGNFSGFWLGIIIVALMGASFLVSGTGSGLGDMGTMSEVKWAV HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHEEECCCCCCCCCCCHHHHHHHH FAFGLVAFGFLGMGAVTIAVDSYGPVTDNAQSVYELSTIEDIPNVSDEFEKHYGFAPRWD HHHHHHHHHHHHCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHH IAKRILEAQDGAGNTFKATAKPVLIGTAVVGATTMIFSIIMMLTEGLSNAAEVNKLGLAH HHHHHHHHCCCCCCCEECCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHH APFLLGLITGGAVIYWFSGASMQAVTTGAYRAVEFIKNNMQLDQNATKASSKDSKKVVQI HHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHH CTEYAQKGMLNIFLGVFFAALGFAFVDPYFFIGYLISIAIFGLYQAIFMANAGGAWDNAK HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC KIVEVDLDAKGTELHDASVVGDTVGDPFKDTSSVALNPVIKFTTLFGLLAVELAVSIGVG EEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH LLTYILAAVFILVACVFVYRSFYGMRIDSTKDPEEFGVVAKEAGSGS HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 12093901 [H]