| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is fabG [H]
Identifier: 50843011
GI number: 50843011
Start: 1653994
End: 1654713
Strand: Reverse
Name: fabG [H]
Synonym: PPA1533
Alternate gene names: 50843011
Gene position: 1654713-1653994 (Counterclockwise)
Preceding gene: 50843015
Following gene: 50843010
Centisome position: 64.63
GC content: 64.58
Gene sequence:
>720_bases ATGAGTCTAGACACCCCGGGGCGCGTCGCCCTCGTCACCGGCGGATCGCGCGGTATCGGTGCTGCGATCGCCGCAGATCT GCACGCACAGGGATACCGAGTGGCCGCAACGAGTCGCTCGGCTACCGCGCCCGAAGGGGTGCTGCCGATCGCCTGCGACG TCACTGACGCCGACTCGGTTGACGTGGCGTTCAGCCAGGTCGAGCAGGAGCTTGGCCCAGTCGAGGTGCTGGTTGCTAAT GCCGGAATTACCCGGGACGGACTGCTCGCCCGCATGAAGGAGGAGGACTTCACCGAGGTCATCGACACTAATCTCACCGG CGCTTACCGCGTTATCCGCCGCGCTGCCAGGGCGATGACCCGGGCCCGTTTTGGCCGCATCGTTTTGACTTCGTCAGTGG TAGGTCTGCTCGGTTCCCCCGGGCAAGTCAACTATGCGGCGTCGAAGGCTGGGATGCTGGGCATGGCCCGCTCTGTGACC CGTGAACTAGGGTCTCGCGGCGTTACCTGCAACCTTGTCGCTCCCGGTTTCATCTCCACGGACATGACCGAGGGACTGCC GGAGAAGCTTGTTTCCGGGTACCTCGAGCGCATCCCGGCCAAGCGGCTGGGATCGGTCGACGATGTCGTTGCGGTCGTCC GATTTCTCGTCTCCGATGCCGCCAGCTACGTCTCTGGGGCTGTGATCCCTGTCGACGGAGGACTCGGCATGGGCCACTGA
Upstream 100 bases:
>100_bases GAACCCGTGCTGCGTCACTCACCTGTCCAGCCTAGGTGCGTCGCGTTGATCAGGTCGAGCCTTCCCAACTCTTGGTCGTA GCGTGCGATAGGTTCATTCT
Downstream 100 bases:
>100_bases CACCATCACATCCATCCACATCGACCGGAAGGACATCACTATGGGACTTCTTGAAGGACGTACCGTCCTCGTCACAGGCG TGACGATGCACACCTCTATC
Product: 3-oxoacyl-[acyl-carrier protein] reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 239; Mature: 238
Protein sequence:
>239_residues MSLDTPGRVALVTGGSRGIGAAIAADLHAQGYRVAATSRSATAPEGVLPIACDVTDADSVDVAFSQVEQELGPVEVLVAN AGITRDGLLARMKEEDFTEVIDTNLTGAYRVIRRAARAMTRARFGRIVLTSSVVGLLGSPGQVNYAASKAGMLGMARSVT RELGSRGVTCNLVAPGFISTDMTEGLPEKLVSGYLERIPAKRLGSVDDVVAVVRFLVSDAASYVSGAVIPVDGGLGMGH
Sequences:
>Translated_239_residues MSLDTPGRVALVTGGSRGIGAAIAADLHAQGYRVAATSRSATAPEGVLPIACDVTDADSVDVAFSQVEQELGPVEVLVAN AGITRDGLLARMKEEDFTEVIDTNLTGAYRVIRRAARAMTRARFGRIVLTSSVVGLLGSPGQVNYAASKAGMLGMARSVT RELGSRGVTCNLVAPGFISTDMTEGLPEKLVSGYLERIPAKRLGSVDDVVAVVRFLVSDAASYVSGAVIPVDGGLGMGH >Mature_238_residues SLDTPGRVALVTGGSRGIGAAIAADLHAQGYRVAATSRSATAPEGVLPIACDVTDADSVDVAFSQVEQELGPVEVLVANA GITRDGLLARMKEEDFTEVIDTNLTGAYRVIRRAARAMTRARFGRIVLTSSVVGLLGSPGQVNYAASKAGMLGMARSVTR ELGSRGVTCNLVAPGFISTDMTEGLPEKLVSGYLERIPAKRLGSVDDVVAVVRFLVSDAASYVSGAVIPVDGGLGMGH
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=40.3361344537815, Blast_Score=163, Evalue=1e-40, Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=38.5542168674699, Blast_Score=155, Evalue=4e-38, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=29.8387096774194, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI4504505, Length=202, Percent_Identity=34.6534653465347, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI4758504, Length=252, Percent_Identity=30.1587301587302, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=30.4878048780488, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI32483357, Length=243, Percent_Identity=29.6296296296296, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=31.1475409836066, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI4503817, Length=212, Percent_Identity=30.6603773584906, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=29.045643153527, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.6442687747036, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI31542939, Length=213, Percent_Identity=29.5774647887324, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4503301, Length=193, Percent_Identity=32.1243523316062, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI66933014, Length=192, Percent_Identity=26.5625, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI210032110, Length=229, Percent_Identity=27.0742358078603, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI223718074, Length=203, Percent_Identity=33.4975369458128, Blast_Score=77, Evalue=9e-15, Organism=Homo sapiens, GI7657478, Length=190, Percent_Identity=34.2105263157895, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI59889578, Length=203, Percent_Identity=28.0788177339901, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI126723750, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=25.3886010362694, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI210032112, Length=214, Percent_Identity=25.2336448598131, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=29.6511627906977, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=26.1603375527426, Blast_Score=68, Evalue=8e-12, Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI209862901, Length=203, Percent_Identity=31.5270935960591, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI19923983, Length=203, Percent_Identity=31.5270935960591, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI50726952, Length=211, Percent_Identity=29.3838862559242, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI150247226, Length=203, Percent_Identity=31.5270935960591, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI25282469, Length=142, Percent_Identity=29.5774647887324, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=44.0329218106996, Blast_Score=216, Evalue=1e-57, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=30.1652892561983, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=35.5102040816327, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=30.8, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=30.8943089430894, Blast_Score=111, Evalue=4e-26, Organism=Escherichia coli, GI1789208, Length=241, Percent_Identity=29.4605809128631, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.6693227091633, Blast_Score=103, Evalue=7e-24, Organism=Escherichia coli, GI2367365, Length=239, Percent_Identity=33.8912133891213, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=28.4584980237154, Blast_Score=96, Evalue=1e-21, Organism=Escherichia coli, GI1788459, Length=242, Percent_Identity=29.3388429752066, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1786701, Length=187, Percent_Identity=31.5508021390374, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=28.4552845528455, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=26.2948207171315, Blast_Score=74, Evalue=1e-14, Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=40.3292181069959, Blast_Score=163, Evalue=6e-41, Organism=Caenorhabditis elegans, GI17555706, Length=240, Percent_Identity=38.3333333333333, Blast_Score=149, Evalue=9e-37, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=32.9365079365079, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=30.241935483871, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=31.3253012048193, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=31.7307692307692, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=28.3524904214559, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=31.8725099601594, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=25.8064516129032, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17562906, Length=257, Percent_Identity=30.3501945525292, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=28.7937743190661, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=30.8, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=201, Percent_Identity=30.8457711442786, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=25.7936507936508, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.5454545454545, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=27.9693486590038, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17559104, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=28.9156626506024, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.1368821292776, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=26.5, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=26.2357414448669, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=26.2745098039216, Blast_Score=69, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=26.2376237623762, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=29.4573643410853, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=24.2307692307692, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=26.3157894736842, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=25, Blast_Score=64, Evalue=1e-10, Organism=Saccharomyces cerevisiae, GI6322861, Length=247, Percent_Identity=31.1740890688259, Blast_Score=105, Evalue=9e-24, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=31.0483870967742, Blast_Score=102, Evalue=8e-23, Organism=Saccharomyces cerevisiae, GI6320089, Length=191, Percent_Identity=30.3664921465969, Blast_Score=88, Evalue=9e-19, Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=36.0995850622407, Blast_Score=143, Evalue=1e-34, Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=32.2709163346614, Blast_Score=111, Evalue=5e-25, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=33.6, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI28571526, Length=245, Percent_Identity=32.6530612244898, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.6290322580645, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI18859837, Length=204, Percent_Identity=34.8039215686275, Blast_Score=101, Evalue=5e-22, Organism=Drosophila melanogaster, GI21357041, Length=245, Percent_Identity=33.0612244897959, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI17737361, Length=252, Percent_Identity=31.7460317460317, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644337, Length=192, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=34.1708542713568, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=29.7959183673469, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI28571387, Length=197, Percent_Identity=31.4720812182741, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI116007236, Length=206, Percent_Identity=32.5242718446602, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI116007234, Length=211, Percent_Identity=34.1232227488152, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI21356301, Length=209, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI116007232, Length=176, Percent_Identity=35.7954545454545, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI24648944, Length=193, Percent_Identity=27.4611398963731, Blast_Score=78, Evalue=4e-15, Organism=Drosophila melanogaster, GI24581726, Length=142, Percent_Identity=28.8732394366197, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI116007238, Length=175, Percent_Identity=33.7142857142857, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI281364494, Length=206, Percent_Identity=30.5825242718447, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI24649181, Length=190, Percent_Identity=28.4210526315789, Blast_Score=73, Evalue=1e-13, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24663911, Length=229, Percent_Identity=31.0043668122271, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641388, Length=209, Percent_Identity=28.7081339712919, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI24648693, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355889, Length=200, Percent_Identity=29.5, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI21355631, Length=182, Percent_Identity=29.1208791208791, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 24691; Mature: 24559
Theoretical pI: Translated: 5.84; Mature: 5.84
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLDTPGRVALVTGGSRGIGAAIAADLHAQGYRVAATSRSATAPEGVLPIACDVTDADSV CCCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCH DVAFSQVEQELGPVEVLVANAGITRDGLLARMKEEDFTEVIDTNLTGAYRVIRRAARAMT HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH RARFGRIVLTSSVVGLLGSPGQVNYAASKAGMLGMARSVTRELGSRGVTCNLVAPGFIST HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC DMTEGLPEKLVSGYLERIPAKRLGSVDDVVAVVRFLVSDAASYVSGAVIPVDGGLGMGH CHHCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC >Mature Secondary Structure SLDTPGRVALVTGGSRGIGAAIAADLHAQGYRVAATSRSATAPEGVLPIACDVTDADSV CCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEECCCCCCCH DVAFSQVEQELGPVEVLVANAGITRDGLLARMKEEDFTEVIDTNLTGAYRVIRRAARAMT HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH RARFGRIVLTSSVVGLLGSPGQVNYAASKAGMLGMARSVTRELGSRGVTCNLVAPGFIST HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC DMTEGLPEKLVSGYLERIPAKRLGSVDDVVAVVRFLVSDAASYVSGAVIPVDGGLGMGH CHHCCHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9534249 [H]