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The map label for this gene is ribF [H]

Identifier: 50842952

GI number: 50842952

Start: 1592777

End: 1593919

Strand: Reverse

Name: ribF [H]

Synonym: PPA1474

Alternate gene names: 50842952

Gene position: 1593919-1592777 (Counterclockwise)

Preceding gene: 50842953

Following gene: 50842951

Centisome position: 62.26

GC content: 60.63

Gene sequence:

>1143_bases
GTGGCAAGAACCAGGAAAAGGCCGTCGAAGAATGGATCTCACGTAACAACGACTGGGTTGACAAGCTCAAGACTGGCCAA
CTCGCCGAGAAGTAAGTCAGACATCGATACGGGCCGCCCGTGTGGCAGCCCGTTGCCGACCACGGTATTCAGTCTCCTGG
CTGTCGCTGCCCTTTACGGATTGGGTGAGGGAAGCACGCTCGGTCGGATTCGGGTTCAACCGGATTCGCACCATAGACTG
CTCAACGTGTCTGTTCCCGAGGAATCGTCGACTGTAGTCATCGGAAACTTCGATGGTGTGCATCGAGGCCACCAGGCCCT
GGTTCAAGAGGCTAAGAGGCTGGATCCGGACGGCTACGTCGTCGTTGTCACTTTCTGGCCCCATCCGCTGACCGTTGTGG
CTCCTGATCAGGCCCCGGCCTTGCTGTGCTCGCTGGAGCGACGGATCGAGTGGCTCAAGGATGCCGGCGCCAGCGAAGTG
CGCGTAGTCAATTTTACTACCGAGATTGCCAGTTGGGCTCCTGCGGCGTTTGTTGAGCGGGTGCTCGGACCCTTACAGCC
CAGGCATGTGCTGGTGGGTCAGAATTTCCGCTTTGGACGTCACGCGGTAGGTACGCCGGATGCTTTGGCCGAACACGGCT
GCTTCCAGGTGCACGCCATGGACCTCGTGGCTATCTCGGGGGTGACGGTATCGTCAACCCGGGTACGCGAGGTCGTCGCT
GCAGGCAAGGTCACCGAGGCAGCAGAACTGCTGGGCAGGCCCTTCGAGGTTGGTGGGGTTGTCGTCATGGGTGACCAGCG
TGGACGTGAACTCGGATTCCCGACGGCCAACCTCGTGGTGCCCCAGGACCGCGCTGTTCCCGCCGACGGTGTGTACGCCG
GATGGTTGGAGCCCACCAGCGGTCCGGACGCTGGCCGTCGACTTCCATCGGCAATTTCGGTGGGCACCAATCCGACTTTC
GATGGGGTCGAGCGTCGCGTCGAGACCTACGTCATTGATCGTGATGACCTGGAGCTGTACGGGGTGGACATCACGGTGAC
CTTCGCTGAGAGGCTGCGCGGCCAGATCAAGTTCGATGGGATTGAGCCATTGATCTCTCAGATGGCCGACGATGTCGAGA
CAGCCAAGCGAGTTTTGTCCTGA

Upstream 100 bases:

>100_bases
CAGGACTTTCCGAAGGTGGCCCAGTTGGTGCGCAATATGGCCTTTGACGACAACAAACTTTCCGATCTCGAGGACACTAT
GTTCTCTGCGGACAAGTACG

Downstream 100 bases:

>100_bases
GGGGTGCGGCCTGGGCGGGTCCGGTTCTCTTGGGGCGTCAGTTGAGCCCGCTGAGCGTGGAATTTCTTTGGGGGCTTCTC
CTCGGTCGGCAATATCTCAT

Product: riboflavin biosynthesis protein RibF (riboflavin kinase)

Products: NA

Alternate protein names: Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MARTRKRPSKNGSHVTTTGLTSSRLANSPRSKSDIDTGRPCGSPLPTTVFSLLAVAALYGLGEGSTLGRIRVQPDSHHRL
LNVSVPEESSTVVIGNFDGVHRGHQALVQEAKRLDPDGYVVVVTFWPHPLTVVAPDQAPALLCSLERRIEWLKDAGASEV
RVVNFTTEIASWAPAAFVERVLGPLQPRHVLVGQNFRFGRHAVGTPDALAEHGCFQVHAMDLVAISGVTVSSTRVREVVA
AGKVTEAAELLGRPFEVGGVVVMGDQRGRELGFPTANLVVPQDRAVPADGVYAGWLEPTSGPDAGRRLPSAISVGTNPTF
DGVERRVETYVIDRDDLELYGVDITVTFAERLRGQIKFDGIEPLISQMADDVETAKRVLS

Sequences:

>Translated_380_residues
MARTRKRPSKNGSHVTTTGLTSSRLANSPRSKSDIDTGRPCGSPLPTTVFSLLAVAALYGLGEGSTLGRIRVQPDSHHRL
LNVSVPEESSTVVIGNFDGVHRGHQALVQEAKRLDPDGYVVVVTFWPHPLTVVAPDQAPALLCSLERRIEWLKDAGASEV
RVVNFTTEIASWAPAAFVERVLGPLQPRHVLVGQNFRFGRHAVGTPDALAEHGCFQVHAMDLVAISGVTVSSTRVREVVA
AGKVTEAAELLGRPFEVGGVVVMGDQRGRELGFPTANLVVPQDRAVPADGVYAGWLEPTSGPDAGRRLPSAISVGTNPTF
DGVERRVETYVIDRDDLELYGVDITVTFAERLRGQIKFDGIEPLISQMADDVETAKRVLS
>Mature_379_residues
ARTRKRPSKNGSHVTTTGLTSSRLANSPRSKSDIDTGRPCGSPLPTTVFSLLAVAALYGLGEGSTLGRIRVQPDSHHRLL
NVSVPEESSTVVIGNFDGVHRGHQALVQEAKRLDPDGYVVVVTFWPHPLTVVAPDQAPALLCSLERRIEWLKDAGASEVR
VVNFTTEIASWAPAAFVERVLGPLQPRHVLVGQNFRFGRHAVGTPDALAEHGCFQVHAMDLVAISGVTVSSTRVREVVAA
GKVTEAAELLGRPFEVGGVVVMGDQRGRELGFPTANLVVPQDRAVPADGVYAGWLEPTSGPDAGRRLPSAISVGTNPTFD
GVERRVETYVIDRDDLELYGVDITVTFAERLRGQIKFDGIEPLISQMADDVETAKRVLS

Specific function: Unknown

COG id: COG0196

COG function: function code H; FAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribF family [H]

Homologues:

Organism=Homo sapiens, GI269973877, Length=130, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1786208, Length=302, Percent_Identity=36.7549668874172, Blast_Score=163, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24644927, Length=130, Percent_Identity=33.8461538461538, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015864
- InterPro:   IPR015865
- InterPro:   IPR002606
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06574 FAD_syn; PF01687 Flavokinase [H]

EC number: =2.7.1.26; =2.7.7.2 [H]

Molecular weight: Translated: 40914; Mature: 40783

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTRKRPSKNGSHVTTTGLTSSRLANSPRSKSDIDTGRPCGSPLPTTVFSLLAVAALYG
CCCCCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
LGEGSTLGRIRVQPDSHHRLLNVSVPEESSTVVIGNFDGVHRGHQALVQEAKRLDPDGYV
CCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEE
VVVTFWPHPLTVVAPDQAPALLCSLERRIEWLKDAGASEVRVVNFTTEIASWAPAAFVER
EEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCHHHHHHH
VLGPLQPRHVLVGQNFRFGRHAVGTPDALAEHGCFQVHAMDLVAISGVTVSSTRVREVVA
HHCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEECCEEECHHHHHHHHH
AGKVTEAAELLGRPFEVGGVVVMGDQRGRELGFPTANLVVPQDRAVPADGVYAGWLEPTS
HCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCC
GPDAGRRLPSAISVGTNPTFDGVERRVETYVIDRDDLELYGVDITVTFAERLRGQIKFDG
CCCHHHCCCCCEECCCCCCHHHHHHHHHHEEECCCCCEEEEEEEEEEEHHHHCCCEEECC
IEPLISQMADDVETAKRVLS
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARTRKRPSKNGSHVTTTGLTSSRLANSPRSKSDIDTGRPCGSPLPTTVFSLLAVAALYG
CCCCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
LGEGSTLGRIRVQPDSHHRLLNVSVPEESSTVVIGNFDGVHRGHQALVQEAKRLDPDGYV
CCCCCCEEEEEECCCCCCEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCEE
VVVTFWPHPLTVVAPDQAPALLCSLERRIEWLKDAGASEVRVVNFTTEIASWAPAAFVER
EEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHCCHHHHHHH
VLGPLQPRHVLVGQNFRFGRHAVGTPDALAEHGCFQVHAMDLVAISGVTVSSTRVREVVA
HHCCCCCCEEEECCCCCCCCCCCCCCHHHHHCCCEEEEEEEEEEECCEEECHHHHHHHHH
AGKVTEAAELLGRPFEVGGVVVMGDQRGRELGFPTANLVVPQDRAVPADGVYAGWLEPTS
HCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCCCCC
GPDAGRRLPSAISVGTNPTFDGVERRVETYVIDRDDLELYGVDITVTFAERLRGQIKFDG
CCCHHHCCCCCEECCCCCCHHHHHHHHHHEEECCCCCEEEEEEEEEEEHHHHCCCEEECC
IEPLISQMADDVETAKRVLS
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7772835; 3023344 [H]