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The map label for this gene is pheT

Identifier: 50842890

GI number: 50842890

Start: 1530001

End: 1532520

Strand: Reverse

Name: pheT

Synonym: PPA1408

Alternate gene names: 50842890

Gene position: 1532520-1530001 (Counterclockwise)

Preceding gene: 50842891

Following gene: 50842888

Centisome position: 59.86

GC content: 60.91

Gene sequence:

>2520_bases
ATGAAGGTTCCTATGTCATGGCTGCAGGCCATGGTTAATCTGCCAGACGGCACCACTACTGACAAGGTGGCCAAGGCGCT
GACCAACCACACAGCGACCGTTGAGAAGGTCGAGGTCGTTGGTGGGGAGCTGACCGGCCCGATCGTGATCGGACACATTC
TTTCTTCGGTTCCCGAACCGCAGAAGAACGGCAAGGTCATTAACTGGTGCCGGGTTGACGTTGGCCCCCGCTATAACGCA
GAGGGACATCCTAAGAACATTGAGGAGGGGGTCGAGGGCCGCGGCATCATCTGTGGCGCTCCCAATGCCGTCGAGGGAGC
CTGGGTTGTCGTCTCTCTGCCTGGCGCCGTGCTCCCCGGCGGATTCGCCATTAGTGCCCGAAAGACGTACGGCCACATGT
CTGACGGCATGCTGTGTGCCTCCGACGAGTTGGGTATCGGTGTCGACGACGCCGGCATCATCACCCTGCCACCATCGGTG
GAGGGTCACCAGCTCGTTCCCGGCGAGGACGCCTTGCCGATTCTCGGGGTCCCCGAAGAGGTCCTGGATGTTGACGTCAC
TCCAGATATCGGCTACTGCATGTCGATGCGCGGCATCGCCCGCGAGGTGGCGCACGCCATGTCGGTACACTTTCGCGATC
CTTACGACGAGGAGCCCATCGGTCCGGTGCTGGGTCCCGTTGCTGTGGACGTCCAATCTGACGCCTGCAGCCAGTTCATC
GCTCTGCCGGTCAGTGGTATGAACCTCGGCGCTCCAACGCCCCGGTTCATCACCGACCGTATCACCCGTGCCGGGATGCG
TCCGATTAATCTGGTTGTCGACGTTACCAACTACGTCATGTTGGAGTCTGGTCAGCCGCTTCATGCCTATGATGCCGACA
ACGTCAGCGGGACGATTGTGGTCCGTAAGGCCCACGAGGGTGAGCATCTATTGACCCTCGACGACACCGATCGCACCCTC
GATCCTGACGATCTAGTCATCGCCGACGACTCGGGAGCCATTGGCCTGGCTGGCGTCATGGGTGGTGCGGCCACCGAAGT
GACTGCTGAGACGACGTCAATCATCCTCGAGGGCGCTCACTTCGACCCGATGACGGTCGCTCGTGCTTACCGACGCCACA
AGCTCGGTTCGGAGGCCTCCCGCCGCTTTGAGCGGGGCGTTGATCCGATTTGCGCCCATACCGCAGCCGTTCGCGCAGCG
GAATTGCTCGCCCAGTACGGCGGTGCCACCGTCGGTGAGCCCACCGTCGTTGGTGAGGTCCCCGAGATGCCACGTCAAAC
GATCAACGCTGATTTACCTAACCGGATTCTCGGCACGAAGGTGCCAACTGAAGAGGTCATCGAGATCTTGACGCGTTCTG
GGGTTAAGGTGACCGCATTGGGGGACTCCCTTCACCTTGTTGCCCCGACTTGGCGTCCTGACCTTGTCGATGCCTACGAC
TATGTTGAGGAGATCGGCCGCAAGATTGGGTTTGATCGCATCAAGGCTGTTCTGCCCCCGAGCTTGGGTGCTAGCGGTCT
GACGAAGGCTCAGCGGGGTCGTCGTCGGGTGCTGCGTTCAGTTGTCGAGGCTGGGTTCGTCGAGCTCATCACCTTGCCAT
TCATCGGGGATAAGGATCTCGACGTTCTCGGCATTAGCGGTGATGACACGCGTCACGCAACTGTCAAACTTGCCAATCCG
CTTGACGATACTCGCCCCTACCTACGCACTACGTTGTTGCCTGGTCTATTCCATGCAGTAACGACGAATATGTCGCGATC
TCAGGATGATCTTGCAGTGTTCGAAAGCGGAACTGTATTCCGCGCCGTCACTCCGGCTGCGGCACCGCGTCCCGGTGTCG
ACGAGCGCCCCTCCGATGAAGTCCTTGCCGAGATCGACGCCGCCTTGCCAGCCCAGCCGCGCATGCTCGCGGCCGTGATC
TGTGGCAGCTGGCTGCCCGATCGCTGGGATGGAGAGTCGGTCAAGGCTGACTGGCGACACGCTGTGCTGGTCGCCCAGAA
GGCTGCTGATGCTCTTGGCGTGAGGCTGGTGCGCAAGGCTGACCGTCAGGCTCCATGGCATCCCGGTCGTTGTGCGGCTC
TCATCGTCGATGGGAAGGTCATTGGCCATGCTGGTGAGTTGCACCCCACAGTAGTGTCGAAGGCTGGTCTGCCTCAGCGC
ACCTGTGCGGTCGAGTTCAATCTAGATGCTTTGGTAGCTGCGGCTCCGCGCGGTGGTGAGGTCATGGCTATTTCAAGCTT
CCCGGTCGCCAAGGAGGACGTTGCCCTGGTCGTTGATAAGTCTGTTGCTGCAGAGGATGTTCGGCAGGCTCTCATCGAGG
GAGCGGGACCGTTGCTTGAGTCCATCGAGCTTTTCGACGTCTACGAGGGCGAGCAGGTGGGTGATAACCGCAAGTCGTTG
GCTTTCAACCTGCGGCTGAGGGGAGCTGACCGAACCTTGACCGACTCTGAGGCCCTCGAGACTCGTGACGCTGCGGTGGC
GCGGGCTGAGGAAACCTGCGGTGCCCAGTTGAGGTCCTGA

Upstream 100 bases:

>100_bases
GCATCGATCGCACGGTGATGTTCCGCAACAATGCCCCCGACCTGCGCGACTTCGTCGAGGGTGACGTTCGATTCAGCCGC
TCACTGAGGGGAGGAGCACG

Downstream 100 bases:

>100_bases
CGCTGCCAATGTCGTCGAGGATCGTGCGAGGCCTTCGCGAGCCGAGGTGAGTTCGGGACACAGACCTCCGGTGAGTCGCG
CAGCTTGATCGATTATGAGG

Product: phenylalanyl-tRNA synthetase beta chain

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 839; Mature: 839

Protein sequence:

>839_residues
MKVPMSWLQAMVNLPDGTTTDKVAKALTNHTATVEKVEVVGGELTGPIVIGHILSSVPEPQKNGKVINWCRVDVGPRYNA
EGHPKNIEEGVEGRGIICGAPNAVEGAWVVVSLPGAVLPGGFAISARKTYGHMSDGMLCASDELGIGVDDAGIITLPPSV
EGHQLVPGEDALPILGVPEEVLDVDVTPDIGYCMSMRGIAREVAHAMSVHFRDPYDEEPIGPVLGPVAVDVQSDACSQFI
ALPVSGMNLGAPTPRFITDRITRAGMRPINLVVDVTNYVMLESGQPLHAYDADNVSGTIVVRKAHEGEHLLTLDDTDRTL
DPDDLVIADDSGAIGLAGVMGGAATEVTAETTSIILEGAHFDPMTVARAYRRHKLGSEASRRFERGVDPICAHTAAVRAA
ELLAQYGGATVGEPTVVGEVPEMPRQTINADLPNRILGTKVPTEEVIEILTRSGVKVTALGDSLHLVAPTWRPDLVDAYD
YVEEIGRKIGFDRIKAVLPPSLGASGLTKAQRGRRRVLRSVVEAGFVELITLPFIGDKDLDVLGISGDDTRHATVKLANP
LDDTRPYLRTTLLPGLFHAVTTNMSRSQDDLAVFESGTVFRAVTPAAAPRPGVDERPSDEVLAEIDAALPAQPRMLAAVI
CGSWLPDRWDGESVKADWRHAVLVAQKAADALGVRLVRKADRQAPWHPGRCAALIVDGKVIGHAGELHPTVVSKAGLPQR
TCAVEFNLDALVAAAPRGGEVMAISSFPVAKEDVALVVDKSVAAEDVRQALIEGAGPLLESIELFDVYEGEQVGDNRKSL
AFNLRLRGADRTLTDSEALETRDAAVARAEETCGAQLRS

Sequences:

>Translated_839_residues
MKVPMSWLQAMVNLPDGTTTDKVAKALTNHTATVEKVEVVGGELTGPIVIGHILSSVPEPQKNGKVINWCRVDVGPRYNA
EGHPKNIEEGVEGRGIICGAPNAVEGAWVVVSLPGAVLPGGFAISARKTYGHMSDGMLCASDELGIGVDDAGIITLPPSV
EGHQLVPGEDALPILGVPEEVLDVDVTPDIGYCMSMRGIAREVAHAMSVHFRDPYDEEPIGPVLGPVAVDVQSDACSQFI
ALPVSGMNLGAPTPRFITDRITRAGMRPINLVVDVTNYVMLESGQPLHAYDADNVSGTIVVRKAHEGEHLLTLDDTDRTL
DPDDLVIADDSGAIGLAGVMGGAATEVTAETTSIILEGAHFDPMTVARAYRRHKLGSEASRRFERGVDPICAHTAAVRAA
ELLAQYGGATVGEPTVVGEVPEMPRQTINADLPNRILGTKVPTEEVIEILTRSGVKVTALGDSLHLVAPTWRPDLVDAYD
YVEEIGRKIGFDRIKAVLPPSLGASGLTKAQRGRRRVLRSVVEAGFVELITLPFIGDKDLDVLGISGDDTRHATVKLANP
LDDTRPYLRTTLLPGLFHAVTTNMSRSQDDLAVFESGTVFRAVTPAAAPRPGVDERPSDEVLAEIDAALPAQPRMLAAVI
CGSWLPDRWDGESVKADWRHAVLVAQKAADALGVRLVRKADRQAPWHPGRCAALIVDGKVIGHAGELHPTVVSKAGLPQR
TCAVEFNLDALVAAAPRGGEVMAISSFPVAKEDVALVVDKSVAAEDVRQALIEGAGPLLESIELFDVYEGEQVGDNRKSL
AFNLRLRGADRTLTDSEALETRDAAVARAEETCGAQLRS
>Mature_839_residues
MKVPMSWLQAMVNLPDGTTTDKVAKALTNHTATVEKVEVVGGELTGPIVIGHILSSVPEPQKNGKVINWCRVDVGPRYNA
EGHPKNIEEGVEGRGIICGAPNAVEGAWVVVSLPGAVLPGGFAISARKTYGHMSDGMLCASDELGIGVDDAGIITLPPSV
EGHQLVPGEDALPILGVPEEVLDVDVTPDIGYCMSMRGIAREVAHAMSVHFRDPYDEEPIGPVLGPVAVDVQSDACSQFI
ALPVSGMNLGAPTPRFITDRITRAGMRPINLVVDVTNYVMLESGQPLHAYDADNVSGTIVVRKAHEGEHLLTLDDTDRTL
DPDDLVIADDSGAIGLAGVMGGAATEVTAETTSIILEGAHFDPMTVARAYRRHKLGSEASRRFERGVDPICAHTAAVRAA
ELLAQYGGATVGEPTVVGEVPEMPRQTINADLPNRILGTKVPTEEVIEILTRSGVKVTALGDSLHLVAPTWRPDLVDAYD
YVEEIGRKIGFDRIKAVLPPSLGASGLTKAQRGRRRVLRSVVEAGFVELITLPFIGDKDLDVLGISGDDTRHATVKLANP
LDDTRPYLRTTLLPGLFHAVTTNMSRSQDDLAVFESGTVFRAVTPAAAPRPGVDERPSDEVLAEIDAALPAQPRMLAAVI
CGSWLPDRWDGESVKADWRHAVLVAQKAADALGVRLVRKADRQAPWHPGRCAALIVDGKVIGHAGELHPTVVSKAGLPQR
TCAVEFNLDALVAAAPRGGEVMAISSFPVAKEDVALVVDKSVAAEDVRQALIEGAGPLLESIELFDVYEGEQVGDNRKSL
AFNLRLRGADRTLTDSEALETRDAAVARAEETCGAQLRS

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=411, Percent_Identity=23.3576642335766, Blast_Score=83, Evalue=1e-15,
Organism=Escherichia coli, GI1788006, Length=851, Percent_Identity=32.9024676850764, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI21355211, Length=407, Percent_Identity=25.7985257985258, Blast_Score=89, Evalue=9e-18,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_PROAC (Q6A7V6)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_056117.1
- ProteinModelPortal:   Q6A7V6
- GeneID:   2931542
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1408
- NMPDR:   fig|267747.1.peg.1394
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- ProtClustDB:   CLSK2763960
- BioCyc:   PACN267747:PPA1408-MONOMER
- BRENDA:   6.1.1.20
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 89259; Mature: 89259

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPMSWLQAMVNLPDGTTTDKVAKALTNHTATVEKVEVVGGELTGPIVIGHILSSVPEP
CCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHCCCCC
QKNGKVINWCRVDVGPRYNAEGHPKNIEEGVEGRGIICGAPNAVEGAWVVVSLPGAVLPG
CCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCC
GFAISARKTYGHMSDGMLCASDELGIGVDDAGIITLPPSVEGHQLVPGEDALPILGVPEE
CEEEEEHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCHH
VLDVDVTPDIGYCMSMRGIAREVAHAMSVHFRDPYDEEPIGPVLGPVAVDVQSDACSQFI
HHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHEE
ALPVSGMNLGAPTPRFITDRITRAGMRPINLVVDVTNYVMLESGQPLHAYDADNVSGTIV
EECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCCEEEE
VRKAHEGEHLLTLDDTDRTLDPDDLVIADDSGAIGLAGVMGGAATEVTAETTSIILEGAH
EEEECCCCEEEEECCCCCCCCCCCEEEECCCCCEEEHHHCCCCCCEEECCCEEEEEECCC
FDPMTVARAYRRHKLGSEASRRFERGVDPICAHTAAVRAAELLAQYGGATVGEPTVVGEV
CCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
PEMPRQTINADLPNRILGTKVPTEEVIEILTRSGVKVTALGDSLHLVAPTWRPDLVDAYD
CCCCHHHCCCCCCCHHHCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCHHHHHH
YVEEIGRKIGFDRIKAVLPPSLGASGLTKAQRGRRRVLRSVVEAGFVELITLPFIGDKDL
HHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
DVLGISGDDTRHATVKLANPLDDTRPYLRTTLLPGLFHAVTTNMSRSQDDLAVFESGTVF
EEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEE
RAVTPAAAPRPGVDERPSDEVLAEIDAALPAQPRMLAAVICGSWLPDRWDGESVKADWRH
EEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHH
AVLVAQKAADALGVRLVRKADRQAPWHPGRCAALIVDGKVIGHAGELHPTVVSKAGLPQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHCCCCCCC
TCAVEFNLDALVAAAPRGGEVMAISSFPVAKEDVALVVDKSVAAEDVRQALIEGAGPLLE
EEEEEECCCEEEEECCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHH
SIELFDVYEGEQVGDNRKSLAFNLRLRGADRTLTDSEALETRDAAVARAEETCGAQLRS
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVPMSWLQAMVNLPDGTTTDKVAKALTNHTATVEKVEVVGGELTGPIVIGHILSSVPEP
CCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHEEEEECCCCCCCHHHHHHHHHCCCCC
QKNGKVINWCRVDVGPRYNAEGHPKNIEEGVEGRGIICGAPNAVEGAWVVVSLPGAVLPG
CCCCCEEEEEEECCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCC
GFAISARKTYGHMSDGMLCASDELGIGVDDAGIITLPPSVEGHQLVPGEDALPILGVPEE
CEEEEEHHHCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCEECCCCCCCCCCCCCHH
VLDVDVTPDIGYCMSMRGIAREVAHAMSVHFRDPYDEEPIGPVLGPVAVDVQSDACSQFI
HHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHEE
ALPVSGMNLGAPTPRFITDRITRAGMRPINLVVDVTNYVMLESGQPLHAYDADNVSGTIV
EECCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCCEEEE
VRKAHEGEHLLTLDDTDRTLDPDDLVIADDSGAIGLAGVMGGAATEVTAETTSIILEGAH
EEEECCCCEEEEECCCCCCCCCCCEEEECCCCCEEEHHHCCCCCCEEECCCEEEEEECCC
FDPMTVARAYRRHKLGSEASRRFERGVDPICAHTAAVRAAELLAQYGGATVGEPTVVGEV
CCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCC
PEMPRQTINADLPNRILGTKVPTEEVIEILTRSGVKVTALGDSLHLVAPTWRPDLVDAYD
CCCCHHHCCCCCCCHHHCCCCCHHHHHHHHHHCCCEEEEECCCEEEEECCCCCCHHHHHH
YVEEIGRKIGFDRIKAVLPPSLGASGLTKAQRGRRRVLRSVVEAGFVELITLPFIGDKDL
HHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
DVLGISGDDTRHATVKLANPLDDTRPYLRTTLLPGLFHAVTTNMSRSQDDLAVFESGTVF
EEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEE
RAVTPAAAPRPGVDERPSDEVLAEIDAALPAQPRMLAAVICGSWLPDRWDGESVKADWRH
EEECCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHH
AVLVAQKAADALGVRLVRKADRQAPWHPGRCAALIVDGKVIGHAGELHPTVVSKAGLPQR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECEEECCCCCCCHHHHHCCCCCCC
TCAVEFNLDALVAAAPRGGEVMAISSFPVAKEDVALVVDKSVAAEDVRQALIEGAGPLLE
EEEEEECCCEEEEECCCCCCEEEEECCCCCCCCEEEEEECHHHHHHHHHHHHHCCCHHHH
SIELFDVYEGEQVGDNRKSLAFNLRLRGADRTLTDSEALETRDAAVARAEETCGAQLRS
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA