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The map label for this gene is pafC [H]

Identifier: 50842863

GI number: 50842863

Start: 1501562

End: 1502530

Strand: Reverse

Name: pafC [H]

Synonym: PPA1381

Alternate gene names: 50842863

Gene position: 1502530-1501562 (Counterclockwise)

Preceding gene: 50842864

Following gene: 50842862

Centisome position: 58.69

GC content: 61.61

Gene sequence:

>969_bases
ATGACGGCTCGCACTGATACCGCCCGTCTGCTAGCTCTTATTCCCTATCTGCGATCTCACCCTGGGGTGGCCGTCACCGA
GGTTGCCCGAGTGTTTGGTGTCAGCACTGACCGTGTGATTGCCGATCTCAAGATTTTATGGATGGTTGGTCTGCCCGGTG
GGATGCCAGACGACCTCATCGACATTGACATGGACGCCGTCGACTCCGACGGCACCATCACCATCACCAATGCTGATGCC
CTGCCACGGCCTATGCGTCTGACGCCCGACGAGGCGTGGTCTCTGCTGGCCGCCTTGCAAGTCATCGCCGATTTGGCTGA
CGACACCGTTCGTCCTGCAGTGGAATCCGCGGTAGAGAAGTTGCGCCAGGTCTGCCCGCAGGCTGGTCCAGATCCGGTGG
AGGCCAGCCTCGAAGCCGATTACGACCCTCGCTCAGAGTGGTTCACCGGGGCCTGTGCTAACAAGTGGCGGATTGAGATC
GTCCATCGACGCGGTGACGACCCTACTCCGCATACCCAGATCGTCGACCCGGTGCGTGTCGAAGTTCGCGACGGTCATCG
CTACCTCGTCGGATGGTCGATGGCTCGCAAGCAGTGGCGCACGTGGCGGCTTGACCGCATCGTCACTGGCAGGCGAGTTG
GGCACGCCACGAATCACGGACGTCCGCCCGAAACCCTCGAATGGTTCTCTGACGTCGTGGACGAGGTGACGCTGACCCTT
GCTCCGCGCGCGGGCTGGGTTGCTGAGTATCACCCGGTGCGCCATGTTGAGAAGGACGGGGACGTGTGGAAGGTGACTTT
TGCCGTCGCCTCTGCGACGTGGCTTGCTGAGCTCATGGTGGGCCTCGGACCAGATGTTCTCTCCGTTGACCCACCTCATG
CTGCAGCTCCTGCCCTTCAGCTGGCGCGCGCTGCGGCTGCCGCAAATAGCATTGAGATTTCGAACCGTGAGGCGGTAGAG
AAATCCTGA

Upstream 100 bases:

>100_bases
TACGCGCCGGCGGTCGTATCATCCTGCTTGCCCCCCAGGAGGCTCGCACTATATTAGCCGAGAGGATCAATGCCGTGCTG
CGGTTGGAAGAGAACGCCTC

Downstream 100 bases:

>100_bases
TGTGGTGGATCTGGGTGTTGGTCTTTGCCGGTGTGCTGCTTGTCGTGGAGATCGTCGTTGGCACGATCTGGTTGTGGCGA
AAGCTCGCGGCTATCTTGGG

Product: regulatory protein

Products: NA

Alternate protein names: Proteasome accessory factor C [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MTARTDTARLLALIPYLRSHPGVAVTEVARVFGVSTDRVIADLKILWMVGLPGGMPDDLIDIDMDAVDSDGTITITNADA
LPRPMRLTPDEAWSLLAALQVIADLADDTVRPAVESAVEKLRQVCPQAGPDPVEASLEADYDPRSEWFTGACANKWRIEI
VHRRGDDPTPHTQIVDPVRVEVRDGHRYLVGWSMARKQWRTWRLDRIVTGRRVGHATNHGRPPETLEWFSDVVDEVTLTL
APRAGWVAEYHPVRHVEKDGDVWKVTFAVASATWLAELMVGLGPDVLSVDPPHAAAPALQLARAAAAANSIEISNREAVE
KS

Sequences:

>Translated_322_residues
MTARTDTARLLALIPYLRSHPGVAVTEVARVFGVSTDRVIADLKILWMVGLPGGMPDDLIDIDMDAVDSDGTITITNADA
LPRPMRLTPDEAWSLLAALQVIADLADDTVRPAVESAVEKLRQVCPQAGPDPVEASLEADYDPRSEWFTGACANKWRIEI
VHRRGDDPTPHTQIVDPVRVEVRDGHRYLVGWSMARKQWRTWRLDRIVTGRRVGHATNHGRPPETLEWFSDVVDEVTLTL
APRAGWVAEYHPVRHVEKDGDVWKVTFAVASATWLAELMVGLGPDVLSVDPPHAAAPALQLARAAAAANSIEISNREAVE
KS
>Mature_321_residues
TARTDTARLLALIPYLRSHPGVAVTEVARVFGVSTDRVIADLKILWMVGLPGGMPDDLIDIDMDAVDSDGTITITNADAL
PRPMRLTPDEAWSLLAALQVIADLADDTVRPAVESAVEKLRQVCPQAGPDPVEASLEADYDPRSEWFTGACANKWRIEIV
HRRGDDPTPHTQIVDPVRVEVRDGHRYLVGWSMARKQWRTWRLDRIVTGRRVGHATNHGRPPETLEWFSDVVDEVTLTLA
PRAGWVAEYHPVRHVEKDGDVWKVTFAVASATWLAELMVGLGPDVLSVDPPHAAAPALQLARAAAAANSIEISNREAVEK
S

Specific function: Part of the pafABC operon, but pafC does not seem to be involved in pupylation or substrate degradation. Appears to play at least a small role in resistance to reactive nitrogen intermediates (RNI) in vitro [H]

COG id: COG2378

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pafC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35408; Mature: 35277

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARTDTARLLALIPYLRSHPGVAVTEVARVFGVSTDRVIADLKILWMVGLPGGMPDDLI
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHEEEEEEECCCCCCCCCEE
DIDMDAVDSDGTITITNADALPRPMRLTPDEAWSLLAALQVIADLADDTVRPAVESAVEK
ECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQVCPQAGPDPVEASLEADYDPRSEWFTGACANKWRIEIVHRRGDDPTPHTQIVDPVRV
HHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEE
EVRDGHRYLVGWSMARKQWRTWRLDRIVTGRRVGHATNHGRPPETLEWFSDVVDEVTLTL
EEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEE
APRAGWVAEYHPVRHVEKDGDVWKVTFAVASATWLAELMVGLGPDVLSVDPPHAAAPALQ
CCCCCCCHHCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHH
LARAAAAANSIEISNREAVEKS
HHHHHHHCCCEECCCCHHCCCC
>Mature Secondary Structure 
TARTDTARLLALIPYLRSHPGVAVTEVARVFGVSTDRVIADLKILWMVGLPGGMPDDLI
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHEEEEEEECCCCCCCCCEE
DIDMDAVDSDGTITITNADALPRPMRLTPDEAWSLLAALQVIADLADDTVRPAVESAVEK
ECCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQVCPQAGPDPVEASLEADYDPRSEWFTGACANKWRIEIVHRRGDDPTPHTQIVDPVRV
HHHHCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEE
EVRDGHRYLVGWSMARKQWRTWRLDRIVTGRRVGHATNHGRPPETLEWFSDVVDEVTLTL
EEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEE
APRAGWVAEYHPVRHVEKDGDVWKVTFAVASATWLAELMVGLGPDVLSVDPPHAAAPALQ
CCCCCCCHHCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHH
LARAAAAANSIEISNREAVEKS
HHHHHHHCCCEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]