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The map label for this gene is ansP [H]

Identifier: 50842806

GI number: 50842806

Start: 1442125

End: 1443633

Strand: Direct

Name: ansP [H]

Synonym: PPA1326

Alternate gene names: 50842806

Gene position: 1442125-1443633 (Clockwise)

Preceding gene: 50842805

Following gene: 50842810

Centisome position: 56.33

GC content: 58.65

Gene sequence:

>1509_bases
ATGACCCATACAACCCAGCGATCACACGAGGACAATCCGCAAGGCCCCAAGGTCAGCGTGACCCGTGACGATCCCCGAGC
CGCCACAATTGAAGAGATCCAACCGATCGTCGATCGCGGCGACCAAGGTTATGCCGAGACCCTGACCAATCGCCAGGTCC
AGATGATGGCGATTGGCGGGGCGATCGGGGTCGGTCTCTTTCTTGGAGCAGGGAGCCGCCTGCGCAGTGCCGGACCAGCG
GTCCTCATCTCCTACGCGTTCTGCGCAGTGATCGCCTTCCTCGTCATGCGAGCGCTCGGCGAGTTGGTCATTCACCGCCC
CTCTAGCGGTTCTTTTGTGTCCTATGCCCGGGAACTTCTCGGCGATCGCTGGGCCTATGCCGTTGGCTGGATGTACATGC
TGAACTGGATGACATCAGGCATCGCTGAGTTGACTGCCATCGGTACCTATCTGCAATTCTGGTGGCCCAGCCTGCCGATG
TGGGTACCCTCACTTGTCGCCTTGATGATCCTCGTGTCGGTCAATCTCATCAGTGTTAAGGCCTTCGGAGAATTCGAGTT
CTGGGCAGCGTTGCTCAAGGTTGTGGCTTTGACAGCGTTCATCATCGTGGCCATCGGCCTAGTGGCCTCCCACGTCAACG
TCGGTGGACACCGCGCAGCGGTGTCGAACCTATGGAGATTCGACGGCGGATTCGCCCCACAGGGGGTTCTGCCCCTCATC
CTGGTCATCCAAGGTGTCATCTTCGCCTATGCCACCATCGAGTTAGTGGGCACCGCCTCCGGGGAGACGCAGAATCCCCG
CAAAGTTATCCCCAAAGCCGTCCATGCGGTTGTCTTCCGGCTCGTTGTGTTCTACCTAGGGTCCTTGGCCTTGCTGGCCA
TGTTGCTGCCGTATAAGGAATACTCCGCCGATGAATCGCCCTTCGTTACGGCATTCTCGGCCATGGGAGTGGGATGGATA
GGCGACGCCATGAATATCGTCGTCATCACCGCTGCGTTCTCCTCGGTGAACTCCGGGTTGTATGCGACGGGTCGAGTCCT
CAAATCGCTGGCGGCCGCAGGAGAAGCTCCAAAATTCGCGGGTACTCTTAACCGATTCAAGACACCCGCCGGTGGCATCC
TCATGACCGCCAGCGTTTTCCTACTGGGGGTCGGACTCGAATACGTCGTTCCCGAGCGTGCCTTCGAGATATCCATTAAC
ACGGCTGCGGTCGGTGTTATCTGGACATGGGCGACGATCTTCTGGTGCCAGTTGGTGTTGCGCCGACGAGTGAATGAGGG
TCGGATCACAGATTCCGGTTTCCATATGCCGGGTTACCCAATTACGGGTATCTTCGGAATTGTCAGCTTGGCCGGGGTGA
CGGCCCTCATGGTGCTCGATCCCCAGAATCGAATCGTGCTGGCTGCAGCCCTGGTGTACATCGCCGTTATGCTCGTCGCC
TGGCCAGCCGTTAAACGCAACAAGGCGCGCCATCCCGAGCTCAACGCCCAGGAAGACATCACTTTTTGA

Upstream 100 bases:

>100_bases
GGAGTGACCGCATCACCCCCTACACTGAACAAAATGCGCGGCGTTTCCGGTTCACCGGAACACCACGTGCAGCTTAATCA
GTCGTACTGGAAGGTCGATG

Downstream 100 bases:

>100_bases
CGAGGCCCCGCACCATGAGGCTACTGGCACACTGGTGCGCGATAAGACTACGAAACAACTCCCTCAGTACACCATTTTCA
TAGCTTCGCGCACCTCCGCC

Product: L-asparagine permease

Products: Proton [Cytoplasm]; L-asparagine [Cytoplasm] [C]

Alternate protein names: L-asparagine transport protein [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTHTTQRSHEDNPQGPKVSVTRDDPRAATIEEIQPIVDRGDQGYAETLTNRQVQMMAIGGAIGVGLFLGAGSRLRSAGPA
VLISYAFCAVIAFLVMRALGELVIHRPSSGSFVSYARELLGDRWAYAVGWMYMLNWMTSGIAELTAIGTYLQFWWPSLPM
WVPSLVALMILVSVNLISVKAFGEFEFWAALLKVVALTAFIIVAIGLVASHVNVGGHRAAVSNLWRFDGGFAPQGVLPLI
LVIQGVIFAYATIELVGTASGETQNPRKVIPKAVHAVVFRLVVFYLGSLALLAMLLPYKEYSADESPFVTAFSAMGVGWI
GDAMNIVVITAAFSSVNSGLYATGRVLKSLAAAGEAPKFAGTLNRFKTPAGGILMTASVFLLGVGLEYVVPERAFEISIN
TAAVGVIWTWATIFWCQLVLRRRVNEGRITDSGFHMPGYPITGIFGIVSLAGVTALMVLDPQNRIVLAAALVYIAVMLVA
WPAVKRNKARHPELNAQEDITF

Sequences:

>Translated_502_residues
MTHTTQRSHEDNPQGPKVSVTRDDPRAATIEEIQPIVDRGDQGYAETLTNRQVQMMAIGGAIGVGLFLGAGSRLRSAGPA
VLISYAFCAVIAFLVMRALGELVIHRPSSGSFVSYARELLGDRWAYAVGWMYMLNWMTSGIAELTAIGTYLQFWWPSLPM
WVPSLVALMILVSVNLISVKAFGEFEFWAALLKVVALTAFIIVAIGLVASHVNVGGHRAAVSNLWRFDGGFAPQGVLPLI
LVIQGVIFAYATIELVGTASGETQNPRKVIPKAVHAVVFRLVVFYLGSLALLAMLLPYKEYSADESPFVTAFSAMGVGWI
GDAMNIVVITAAFSSVNSGLYATGRVLKSLAAAGEAPKFAGTLNRFKTPAGGILMTASVFLLGVGLEYVVPERAFEISIN
TAAVGVIWTWATIFWCQLVLRRRVNEGRITDSGFHMPGYPITGIFGIVSLAGVTALMVLDPQNRIVLAAALVYIAVMLVA
WPAVKRNKARHPELNAQEDITF
>Mature_501_residues
THTTQRSHEDNPQGPKVSVTRDDPRAATIEEIQPIVDRGDQGYAETLTNRQVQMMAIGGAIGVGLFLGAGSRLRSAGPAV
LISYAFCAVIAFLVMRALGELVIHRPSSGSFVSYARELLGDRWAYAVGWMYMLNWMTSGIAELTAIGTYLQFWWPSLPMW
VPSLVALMILVSVNLISVKAFGEFEFWAALLKVVALTAFIIVAIGLVASHVNVGGHRAAVSNLWRFDGGFAPQGVLPLIL
VIQGVIFAYATIELVGTASGETQNPRKVIPKAVHAVVFRLVVFYLGSLALLAMLLPYKEYSADESPFVTAFSAMGVGWIG
DAMNIVVITAAFSSVNSGLYATGRVLKSLAAAGEAPKFAGTLNRFKTPAGGILMTASVFLLGVGLEYVVPERAFEISINT
AAVGVIWTWATIFWCQLVLRRRVNEGRITDSGFHMPGYPITGIFGIVSLAGVTALMVLDPQNRIVLAAALVYIAVMLVAW
PAVKRNKARHPELNAQEDITF

Specific function: Unknown

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=366, Percent_Identity=24.0437158469945, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI258614003, Length=424, Percent_Identity=22.877358490566, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI258645169, Length=423, Percent_Identity=21.9858156028369, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI258614005, Length=424, Percent_Identity=22.877358490566, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI181337167, Length=401, Percent_Identity=20.9476309226933, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081915, Length=453, Percent_Identity=48.7858719646799, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1786302, Length=425, Percent_Identity=39.7647058823529, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1786602, Length=446, Percent_Identity=35.4260089686099, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1786789, Length=462, Percent_Identity=35.9307359307359, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1790653, Length=466, Percent_Identity=33.9055793991416, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI48994972, Length=468, Percent_Identity=31.4102564102564, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI87081708, Length=458, Percent_Identity=33.1877729257642, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI1789017, Length=448, Percent_Identity=31.9196428571429, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1788480, Length=470, Percent_Identity=31.2765957446809, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI87082023, Length=358, Percent_Identity=23.463687150838, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=429, Percent_Identity=22.6107226107226, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=413, Percent_Identity=23.4866828087167, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=344, Percent_Identity=22.3837209302326, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324061, Length=402, Percent_Identity=32.089552238806, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320772, Length=475, Percent_Identity=30.7368421052632, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324990, Length=443, Percent_Identity=30.4740406320542, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6322892, Length=443, Percent_Identity=30.2483069977427, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6321053, Length=436, Percent_Identity=29.3577981651376, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324059, Length=502, Percent_Identity=30.2788844621514, Blast_Score=164, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6320717, Length=440, Percent_Identity=27.2727272727273, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324924, Length=407, Percent_Identity=30.4668304668305, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322967, Length=460, Percent_Identity=28.4782608695652, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6319824, Length=445, Percent_Identity=24.9438202247191, Blast_Score=149, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6320251, Length=464, Percent_Identity=25.6465517241379, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6321629, Length=399, Percent_Identity=27.0676691729323, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319542, Length=484, Percent_Identity=26.2396694214876, Blast_Score=146, Evalue=6e-36,
Organism=Saccharomyces cerevisiae, GI6324553, Length=348, Percent_Identity=32.4712643678161, Blast_Score=146, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319608, Length=474, Percent_Identity=26.5822784810127, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324981, Length=468, Percent_Identity=27.5641025641026, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319543, Length=341, Percent_Identity=28.1524926686217, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320364, Length=539, Percent_Identity=23.3766233766234, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666159, Length=427, Percent_Identity=24.5901639344262, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI221512776, Length=427, Percent_Identity=24.5901639344262, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24668806, Length=426, Percent_Identity=23.4741784037559, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356285, Length=426, Percent_Identity=23.4741784037559, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24668802, Length=426, Percent_Identity=23.4741784037559, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667468, Length=344, Percent_Identity=23.546511627907, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007818, Length=375, Percent_Identity=26.1333333333333, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85725152, Length=375, Percent_Identity=26.1333333333333, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54179; Mature: 54048

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTTQRSHEDNPQGPKVSVTRDDPRAATIEEIQPIVDRGDQGYAETLTNRQVQMMAIGG
CCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCEEEEEECH
AIGVGLFLGAGSRLRSAGPAVLISYAFCAVIAFLVMRALGELVIHRPSSGSFVSYARELL
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
GDRWAYAVGWMYMLNWMTSGIAELTAIGTYLQFWWPSLPMWVPSLVALMILVSVNLISVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEE
AFGEFEFWAALLKVVALTAFIIVAIGLVASHVNVGGHRAAVSNLWRFDGGFAPQGVLPLI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
LVIQGVIFAYATIELVGTASGETQNPRKVIPKAVHAVVFRLVVFYLGSLALLAMLLPYKE
HHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
YSADESPFVTAFSAMGVGWIGDAMNIVVITAAFSSVNSGLYATGRVLKSLAAAGEAPKFA
CCCCCCCHHHHHHHCCCHHHCCCHHHHEEEHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH
GTLNRFKTPAGGILMTASVFLLGVGLEYVVPERAFEISINTAAVGVIWTWATIFWCQLVL
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
RRRVNEGRITDSGFHMPGYPITGIFGIVSLAGVTALMVLDPQNRIVLAAALVYIAVMLVA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
WPAVKRNKARHPELNAQEDITF
HHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
THTTQRSHEDNPQGPKVSVTRDDPRAATIEEIQPIVDRGDQGYAETLTNRQVQMMAIGG
CCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHCCCCEEEEEECH
AIGVGLFLGAGSRLRSAGPAVLISYAFCAVIAFLVMRALGELVIHRPSSGSFVSYARELL
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHH
GDRWAYAVGWMYMLNWMTSGIAELTAIGTYLQFWWPSLPMWVPSLVALMILVSVNLISVK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEE
AFGEFEFWAALLKVVALTAFIIVAIGLVASHVNVGGHRAAVSNLWRFDGGFAPQGVLPLI
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
LVIQGVIFAYATIELVGTASGETQNPRKVIPKAVHAVVFRLVVFYLGSLALLAMLLPYKE
HHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
YSADESPFVTAFSAMGVGWIGDAMNIVVITAAFSSVNSGLYATGRVLKSLAAAGEAPKFA
CCCCCCCHHHHHHHCCCHHHCCCHHHHEEEHHHHHHCCCHHHHHHHHHHHHHCCCCCHHH
GTLNRFKTPAGGILMTASVFLLGVGLEYVVPERAFEISINTAAVGVIWTWATIFWCQLVL
HHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHH
RRRVNEGRITDSGFHMPGYPITGIFGIVSLAGVTALMVLDPQNRIVLAAALVYIAVMLVA
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHH
WPAVKRNKARHPELNAQEDITF
HHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-asparagine [Periplasm]; Proton [Periplasm] [C]

Specific reaction: L-asparagine [Periplasm] + Proton [Periplasm] = Proton [Cytoplasm] + L-asparagine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]