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The map label for this gene is nudC [H]

Identifier: 50842798

GI number: 50842798

Start: 1430845

End: 1431597

Strand: Reverse

Name: nudC [H]

Synonym: PPA1318

Alternate gene names: 50842798

Gene position: 1431597-1430845 (Counterclockwise)

Preceding gene: 50842799

Following gene: 50842794

Centisome position: 55.92

GC content: 60.56

Gene sequence:

>753_bases
ATGACAGGGTGGTCGCGGTTCCCACTGAGGGTGAGCGCGACGATCAGCACGACCTACTGCCTGCTTGGTGTCGTCGACGG
GGTGCCTTGGTTTACCCGTCGTACCAATGAGCCACGTCCGGAGGCTCGGAGTGTGCGCGCGGTTGATCTTGTCCCGGTTG
ATCGGGAACTCGTCATGTCGGCGGTGGCAGCGCTGGCTTGGCATGAGAGCAACCCGTTATGCCCACGATGTGGGCAGTCC
ACCCGCGTTACGAGCGGTGGGCCGGCCCGAGTCTGTCCCCAGGGCCATTACGTATTCCCGCGTACAGACCCGGCCATCAT
TACCGCAGTACTTGACGACGAGGACCGCATCGTGCTTGCCCGTCAACGTTCCTGGGAACCGCATCGTAGGTCGGTATTGG
CGGGATTCGTCGAAACTGGCGAACCAGCAGAGCATGCTGTGGTACGTGAGGTTGCCGAGGAAACAACTCTGACGATCACC
TCGGCCTGCTATATAGGGTCGCAGGCATGGCCGTTCCCCCGATCGCTCATGTTCGGCTACGTAGCTCGGGCGACCGGAAC
CATCGATGTCGGCCACGACGAGCTAGCGGAGGCTAGTTTTCTCAGCCGTCAAGAAGTATCCGGCCAAGTTAATGCTGGGC
GTCTCCAGTTGCCACCGACTCTGTCCATAGCAAGAGCCCTTATTGACGCGTGGTTAGAACACCGACTTCCGGAGCCAGAG
AGCGGGTTTGACTTATCGGCCCCACTGAGGTGA

Upstream 100 bases:

>100_bases
CATGCTGATCGGAACGATGATAAGGCAAATCGGGCTAGGTGGGATGATCCGGCTGCCCAGTTGTTGCTCATTGATCCCTA
CGACAAGGTTGTCATGGCTC

Downstream 100 bases:

>100_bases
TAGCCCATCGACCTTGAGACTCCGGTCTCATCAGGAAGTGCGACTTTCTTCCCACCGGCGCTGAATCCCAGAACGTCGAT
CATTAGCCCGGTCAATCGCC

Product: NADH pyrophosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTGWSRFPLRVSATISTTYCLLGVVDGVPWFTRRTNEPRPEARSVRAVDLVPVDRELVMSAVAALAWHESNPLCPRCGQS
TRVTSGGPARVCPQGHYVFPRTDPAIITAVLDDEDRIVLARQRSWEPHRRSVLAGFVETGEPAEHAVVREVAEETTLTIT
SACYIGSQAWPFPRSLMFGYVARATGTIDVGHDELAEASFLSRQEVSGQVNAGRLQLPPTLSIARALIDAWLEHRLPEPE
SGFDLSAPLR

Sequences:

>Translated_250_residues
MTGWSRFPLRVSATISTTYCLLGVVDGVPWFTRRTNEPRPEARSVRAVDLVPVDRELVMSAVAALAWHESNPLCPRCGQS
TRVTSGGPARVCPQGHYVFPRTDPAIITAVLDDEDRIVLARQRSWEPHRRSVLAGFVETGEPAEHAVVREVAEETTLTIT
SACYIGSQAWPFPRSLMFGYVARATGTIDVGHDELAEASFLSRQEVSGQVNAGRLQLPPTLSIARALIDAWLEHRLPEPE
SGFDLSAPLR
>Mature_249_residues
TGWSRFPLRVSATISTTYCLLGVVDGVPWFTRRTNEPRPEARSVRAVDLVPVDRELVMSAVAALAWHESNPLCPRCGQST
RVTSGGPARVCPQGHYVFPRTDPAIITAVLDDEDRIVLARQRSWEPHRRSVLAGFVETGEPAEHAVVREVAEETTLTITS
ACYIGSQAWPFPRSLMFGYVARATGTIDVGHDELAEASFLSRQEVSGQVNAGRLQLPPTLSIARALIDAWLEHRLPEPES
GFDLSAPLR

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=190, Percent_Identity=35.7894736842105, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI50593112, Length=198, Percent_Identity=37.3737373737374, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI48994995, Length=212, Percent_Identity=33.0188679245283, Blast_Score=88, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321371, Length=265, Percent_Identity=26.7924528301887, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 27496; Mature: 27365

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWSRFPLRVSATISTTYCLLGVVDGVPWFTRRTNEPRPEARSVRAVDLVPVDRELVMS
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCEEEEEEECCCHHHHHH
AVAALAWHESNPLCPRCGQSTRVTSGGPARVCPQGHYVFPRTDPAIITAVLDDEDRIVLA
HHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCEEEE
RQRSWEPHRRSVLAGFVETGEPAEHAVVREVAEETTLTITSACYIGSQAWPFPRSLMFGY
ECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEHEEECCCCCCCHHHHHHHH
VARATGTIDVGHDELAEASFLSRQEVSGQVNAGRLQLPPTLSIARALIDAWLEHRLPEPE
HHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCC
SGFDLSAPLR
CCCCCCCCCC
>Mature Secondary Structure 
TGWSRFPLRVSATISTTYCLLGVVDGVPWFTRRTNEPRPEARSVRAVDLVPVDRELVMS
CCCCCCCEEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCHHHCEEEEEEECCCHHHHHH
AVAALAWHESNPLCPRCGQSTRVTSGGPARVCPQGHYVFPRTDPAIITAVLDDEDRIVLA
HHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCCCEECCCCCCEEEEEEECCCCCEEEE
RQRSWEPHRRSVLAGFVETGEPAEHAVVREVAEETTLTITSACYIGSQAWPFPRSLMFGY
ECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEEHEEECCCCCCCHHHHHHHH
VARATGTIDVGHDELAEASFLSRQEVSGQVNAGRLQLPPTLSIARALIDAWLEHRLPEPE
HHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCC
SGFDLSAPLR
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]