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The map label for this gene is deoC1

Identifier: 50842695

GI number: 50842695

Start: 1323109

End: 1323762

Strand: Reverse

Name: deoC1

Synonym: PPA1214

Alternate gene names: 50842695

Gene position: 1323762-1323109 (Counterclockwise)

Preceding gene: 50842696

Following gene: 50842694

Centisome position: 51.7

GC content: 61.01

Gene sequence:

>654_bases
ATGAGCATTGCCGCTCTCATCGATCACACGCTGTTAGCCCCCGATGTCACGGCGCAGCACATCAGGACCCTGTGCCGCGA
GGCCGTCGATCATGGTTTCGCCACTGTTTGTGTCAGCCCAACCCGGGTGAGGCTGGCAGCAGACGAGCTAGCCGGACACG
CCCCACGTGTGTGTTCGGTCATCGGTTTCCCCTCTGGCGCACACCTGAGCGAGATTAGGGCCGCTGAAACCAAGGCTGCC
GTCAATGATGGCGCTGATGAGATCGACATGGTCATCAACGTAGGAGCCGTCAAAGATGATGACTGGGACACCGTCGAGTC
TGACATATCCGCCGTCGTCGACGCCGCCGGTATGGCCATAGTCAAGGTTATCCTTGAAGTCAGCGAGCTCACCGACGAGG
AGATTACCCGTGCCTGCCAGGCCGCCGAACGGTGTGGAGCCGATTTCGTCAAGACATCTACGGGATACTCTCGACACGGT
GCTACCGCCGAGGCTGTCTCACTTATGCGCCGTACTGTGGGCGATCGGCTAGGGGTCAAAGCATCCGGCGGCATTCGTAC
CCACAACGACGTGGCGACGATGCTAAGGGCTGGTGCCACCCGCATCGGTGCCTCCGCCGGGGTCGCCCTCCTTGTTGACG
AGGAGGCACTGTGA

Upstream 100 bases:

>100_bases
GACGGCCCCGCGTCATGTCGTGGCCTCGCATTGGCACGAATGTGCCACCCGAAAGGATGACGGCGGCCCTACAGTGATCG
CTCTGAGCAAAGGAGTTCAC

Downstream 100 bases:

>100_bases
TCACCAAAGACACCACTGTCGTCAACGACACGGACGTGGATCGTGGCATCCCCAACGCGTCGTGGGGCCTCATCAAGGAC
CACACCTTGCAGTTGCGTGA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 1; DERA 1; Deoxyriboaldolase 1

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MSIAALIDHTLLAPDVTAQHIRTLCREAVDHGFATVCVSPTRVRLAADELAGHAPRVCSVIGFPSGAHLSEIRAAETKAA
VNDGADEIDMVINVGAVKDDDWDTVESDISAVVDAAGMAIVKVILEVSELTDEEITRACQAAERCGADFVKTSTGYSRHG
ATAEAVSLMRRTVGDRLGVKASGGIRTHNDVATMLRAGATRIGASAGVALLVDEEAL

Sequences:

>Translated_217_residues
MSIAALIDHTLLAPDVTAQHIRTLCREAVDHGFATVCVSPTRVRLAADELAGHAPRVCSVIGFPSGAHLSEIRAAETKAA
VNDGADEIDMVINVGAVKDDDWDTVESDISAVVDAAGMAIVKVILEVSELTDEEITRACQAAERCGADFVKTSTGYSRHG
ATAEAVSLMRRTVGDRLGVKASGGIRTHNDVATMLRAGATRIGASAGVALLVDEEAL
>Mature_216_residues
SIAALIDHTLLAPDVTAQHIRTLCREAVDHGFATVCVSPTRVRLAADELAGHAPRVCSVIGFPSGAHLSEIRAAETKAAV
NDGADEIDMVINVGAVKDDDWDTVESDISAVVDAAGMAIVKVILEVSELTDEEITRACQAAERCGADFVKTSTGYSRHGA
TAEAVSLMRRTVGDRLGVKASGGIRTHNDVATMLRAGATRIGASAGVALLVDEEAL

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=217, Percent_Identity=35.9447004608295, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1790841, Length=204, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17533015, Length=205, Percent_Identity=34.1463414634146, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI19922098, Length=245, Percent_Identity=32.2448979591837, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC1_PROAC (Q6A8F1)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055922.1
- ProteinModelPortal:   Q6A8F1
- SMR:   Q6A8F1
- GeneID:   2931397
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1214
- NMPDR:   fig|267747.1.peg.1199
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   CLSK2763821
- BioCyc:   PACN267747:PPA1214-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 22617; Mature: 22486

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: ACT_SITE 151-151 ACT_SITE 180-180

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAALIDHTLLAPDVTAQHIRTLCREAVDHGFATVCVSPTRVRLAADELAGHAPRVCSV
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHEEEHHHHCCCCCHHHHH
IGFPSGAHLSEIRAAETKAAVNDGADEIDMVINVGAVKDDDWDTVESDISAVVDAAGMAI
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VKVILEVSELTDEEITRACQAAERCGADFVKTSTGYSRHGATAEAVSLMRRTVGDRLGVK
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
ASGGIRTHNDVATMLRAGATRIGASAGVALLVDEEAL
CCCCCCCHHHHHHHHHHCHHHCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SIAALIDHTLLAPDVTAQHIRTLCREAVDHGFATVCVSPTRVRLAADELAGHAPRVCSV
CHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHEEEHHHHCCCCCHHHHH
IGFPSGAHLSEIRAAETKAAVNDGADEIDMVINVGAVKDDDWDTVESDISAVVDAAGMAI
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
VKVILEVSELTDEEITRACQAAERCGADFVKTSTGYSRHGATAEAVSLMRRTVGDRLGVK
HHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
ASGGIRTHNDVATMLRAGATRIGASAGVALLVDEEAL
CCCCCCCHHHHHHHHHHCHHHCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA