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The map label for this gene is secF

Identifier: 50842643

GI number: 50842643

Start: 1263564

End: 1264739

Strand: Direct

Name: secF

Synonym: PPA1163

Alternate gene names: 50842643

Gene position: 1263564-1264739 (Clockwise)

Preceding gene: 50842642

Following gene: 50842644

Centisome position: 49.35

GC content: 57.06

Gene sequence:

>1176_bases
ATGACTGACGACATGAACGCCCAGACGTCGTCTGTTGCCACAAAGCGTCCTAGTGATGGCGCGACCGGCAAGAAGCGCAA
GCGTAGCTTCACTCATGCCCTGTACACCGGTGAGATCTCCTACGGGTTTATCCAGCGCCGCAAGGTCTGGTACACCATCA
CTGCAGTCGTCATCATCATCTCGTTTATCGGCCTGCTAGTACGCGGTCTGAACCTCGGTATTGAGTTCAAGGGTGGCGTG
CAGTTCCGAGCTCCGGCCCACGTTGCTACCTCTACTATTGACGACGTCCGAAAGTCGGTGCTGTCCTCGGGTGCTCCCGA
TATGGACGCAACCGAGGTCGTCAGCCTCGGCTCCGATGCTGTCCAGGTGCAGACTCGGGCTCTTAACAATGACGAAACTA
CGAAGGTTCAGGAGGCCATTGCTAAGGCCACCGGGACGAAGATGAGCTCGGTCACCTACTCTAAGGTCGGCAGTCAGTGG
GGTGAGCAGATCACCGGCAAGGCCATTAAGGCGTTGGTCGTATTCCTGGTCTTGGTGATGCTGCAGATTTGGGCCTATTT
CCGGCATTGGAAGATGTCTATTGCTGCTTTGGTGGCCCTTTTACACGATCTCATCGTCACCATCGGTATCTATGCGTTGG
TTGGATTCACGGTTTCACCGTCAACAGTCATTGGTGTGCTAACGATTCTGGGCTATTCGTTGTACGACACCGTCGTGGTC
TTCGACAAGGTGCGCGAGAACGTCCAGGACATCGACAAGCGTGATTACACCTTTGCTGAGGGCGCTAACCGAGCCGTCAA
CCAGGTGCTGGTGCGGTCTATTAACACCACCATCGTGGGCGTGCTACCTGTCGCCGCGCTGCTCTTCGCTGGTGCCTTTG
TGCTGGGGTCCGGGCCGCTCGAAGACCTTGGTCTGGCCCTGTTCGTCGGAATGATCGTTGGTGCCTACTCTTCGATCTTC
ATTGCAACCCCGGTGTTTACCCAATTGCGTGAGCACGAGCCAGCCATGAAAGAGCACACCGCGCGTGTTTTGCGTCGTCG
TGAGCGGGCCGCTCAGAAGGCACCACGGGTAACCGCTGAGACCGTTGCCGCGGAAGGTCCACGCGACGTTACGACTATCA
CCGGGAGCGATCGTCACCAGCCACGTCGTTCTACCCGTGCCGAGAGGAAGAAATGA

Upstream 100 bases:

>100_bases
GCGGAGCATATGGGCGTGACTGAGAGCCAGCTGCTTGGTCGGAGAAGCAGACGATCTGCTTCAAGAGCAAAGCGCACCAT
CGAGTCGGAGGAGGCCTGAG

Downstream 100 bases:

>100_bases
CCTACCGTAAGGACCTCATTGCCAGCCTGATCCGGGATGTCCCGGACTTTCCGGAGCCCGGGGTCACTTTTAAGGACATC
ACTCCGCTACTGGCAAATCC

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTDDMNAQTSSVATKRPSDGATGKKRKRSFTHALYTGEISYGFIQRRKVWYTITAVVIIISFIGLLVRGLNLGIEFKGGV
QFRAPAHVATSTIDDVRKSVLSSGAPDMDATEVVSLGSDAVQVQTRALNNDETTKVQEAIAKATGTKMSSVTYSKVGSQW
GEQITGKAIKALVVFLVLVMLQIWAYFRHWKMSIAALVALLHDLIVTIGIYALVGFTVSPSTVIGVLTILGYSLYDTVVV
FDKVRENVQDIDKRDYTFAEGANRAVNQVLVRSINTTIVGVLPVAALLFAGAFVLGSGPLEDLGLALFVGMIVGAYSSIF
IATPVFTQLREHEPAMKEHTARVLRRRERAAQKAPRVTAETVAAEGPRDVTTITGSDRHQPRRSTRAERKK

Sequences:

>Translated_391_residues
MTDDMNAQTSSVATKRPSDGATGKKRKRSFTHALYTGEISYGFIQRRKVWYTITAVVIIISFIGLLVRGLNLGIEFKGGV
QFRAPAHVATSTIDDVRKSVLSSGAPDMDATEVVSLGSDAVQVQTRALNNDETTKVQEAIAKATGTKMSSVTYSKVGSQW
GEQITGKAIKALVVFLVLVMLQIWAYFRHWKMSIAALVALLHDLIVTIGIYALVGFTVSPSTVIGVLTILGYSLYDTVVV
FDKVRENVQDIDKRDYTFAEGANRAVNQVLVRSINTTIVGVLPVAALLFAGAFVLGSGPLEDLGLALFVGMIVGAYSSIF
IATPVFTQLREHEPAMKEHTARVLRRRERAAQKAPRVTAETVAAEGPRDVTTITGSDRHQPRRSTRAERKK
>Mature_390_residues
TDDMNAQTSSVATKRPSDGATGKKRKRSFTHALYTGEISYGFIQRRKVWYTITAVVIIISFIGLLVRGLNLGIEFKGGVQ
FRAPAHVATSTIDDVRKSVLSSGAPDMDATEVVSLGSDAVQVQTRALNNDETTKVQEAIAKATGTKMSSVTYSKVGSQWG
EQITGKAIKALVVFLVLVMLQIWAYFRHWKMSIAALVALLHDLIVTIGIYALVGFTVSPSTVIGVLTILGYSLYDTVVVF
DKVRENVQDIDKRDYTFAEGANRAVNQVLVRSINTTIVGVLPVAALLFAGAFVLGSGPLEDLGLALFVGMIVGAYSSIFI
ATPVFTQLREHEPAMKEHTARVLRRRERAAQKAPRVTAETVAAEGPRDVTTITGSDRHQPRRSTRAERKK

Specific function: Involved in protein export [H]

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=327, Percent_Identity=25.6880733944954, Blast_Score=93, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022813
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 42588; Mature: 42457

Theoretical pI: Translated: 10.36; Mature: 10.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCEEEECCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
TDDMNAQTSSVATKRPSDGATGKKRKRSFTHALYTGEISYGFIQRRKVWYTITAVVIII
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHH
SFIGLLVRGLNLGIEFKGGVQFRAPAHVATSTIDDVRKSVLSSGAPDMDATEVVSLGSDA
HHHHHHHHHHCCCEEECCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCH
VQVQTRALNNDETTKVQEAIAKATGTKMSSVTYSKVGSQWGEQITGKAIKALVVFLVLVM
HHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQIWAYFRHWKMSIAALVALLHDLIVTIGIYALVGFTVSPSTVIGVLTILGYSLYDTVVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
FDKVRENVQDIDKRDYTFAEGANRAVNQVLVRSINTTIVGVLPVAALLFAGAFVLGSGPL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDLGLALFVGMIVGAYSSIFIATPVFTQLREHEPAMKEHTARVLRRRERAAQKAPRVTAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHH
TVAAEGPRDVTTITGSDRHQPRRSTRAERKK
HHHCCCCCCEEEECCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]