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The map label for this gene is ruvB

Identifier: 50842640

GI number: 50842640

Start: 1260311

End: 1261339

Strand: Direct

Name: ruvB

Synonym: PPA1160

Alternate gene names: 50842640

Gene position: 1260311-1261339 (Clockwise)

Preceding gene: 50842639

Following gene: 50842641

Centisome position: 49.23

GC content: 60.74

Gene sequence:

>1029_bases
ATGTCGGTGGAACACTCGCCCGTCGATCCGTCGGCCGAACCCCCTGAAAAGGCTGAAGAAGCAGCTTTACGTCCTGGCGC
ACTGGCAGAGTTCGGAGGACAACAGCGAGTCGCCGATCAGCTAGGTCTGGTCCTTGCCGCGTCGAAGTCCCGTGGTACGA
CCCCCGACCATGTTCTGCTGTCGGGACCGCCAGGTCTTGGGAAGACGACCTTGGCCATGATTATTGCCTCCGAAATGTCG
GCACCAATCCGTATTTCCTCGGGTCCTGCCATTCAGCACGCCGGGGATCTGGCTGCGATCTTGTCCTCGTTAGTACCCGG
CGAAGTGTTCTTTCTTGACGAGATCCACCGGATGTCCAAGCCTGCCGAAGAAATGCTTTACCTGGCTATGGAGGATTTCC
GGGTCGACGTTGTTGTGGGTAAAGGGCCGGGAGCTACCGCGATTCCGATTGAGATACCACCGTTCACGCTGGTGGGGGCG
ACGACGCGAGCCGGGCTGCTTCCGGGGCCGTTGCGTGACCGCTTCGGCTTTACTGCCCAGCTTGACTACTACGAGGTAGC
TGATCTCGAACGGATCGTGACGCGATCGGCCGGGGTCATCGGAGTTGAGCTTGCTGAAGGTGCGGCACACACGATTGCGT
CGCGGTCTCGCGGTACGCCCCGTATCGCGAACCGCTTGCTGCGACGGGTCCGTGACTGGGCAGACGTTCATCATGAGTCT
CCTGTGACGCCGCAAGGAGCCGAGACCGCCCTTGACCTCTACGAGGTTGATCCGTTGGGTCTGGACCGCCTCGACAGGGC
GGTTCTCCATGCGGTGTGTCTAAAGTTCGGGGGCGGGCCGGTAGGCTTGTCAACCCTTGCTATTAGCGTGGGGGAGGAGC
CACAGACGGTTGAGGAAGTTGCTGAACCTTTCCTGGTACGACTTGGTTTTCTCATGCGCACCCCGAGGGGCCGCGTCCCT
ACTGATCGAGCTTGGCGACATCTCGGCCTTGAACCACCTCCCGACAGTTCCGGTGAGGGGCTGTTCTGA

Upstream 100 bases:

>100_bases
CTATGAGCATCGGCAACCTCATGCGAGCGGCGTTGCGTAGTTTGGCGCGGTGACATGTCGGATGCCTCTGGCAGACTGAT
AAGAGTCGTCAGGAAGGAGA

Downstream 100 bases:

>100_bases
CCACATTGACCGAGTCGGGGTAGCATGACCCCGGTCACACCCGAAGACAAGGAACGTTTTATGCCTCTTCTCGCTAGCCC
GCTGGGCGGATTCATGCCCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSVEHSPVDPSAEPPEKAEEAALRPGALAEFGGQQRVADQLGLVLAASKSRGTTPDHVLLSGPPGLGKTTLAMIIASEMS
APIRISSGPAIQHAGDLAAILSSLVPGEVFFLDEIHRMSKPAEEMLYLAMEDFRVDVVVGKGPGATAIPIEIPPFTLVGA
TTRAGLLPGPLRDRFGFTAQLDYYEVADLERIVTRSAGVIGVELAEGAAHTIASRSRGTPRIANRLLRRVRDWADVHHES
PVTPQGAETALDLYEVDPLGLDRLDRAVLHAVCLKFGGGPVGLSTLAISVGEEPQTVEEVAEPFLVRLGFLMRTPRGRVP
TDRAWRHLGLEPPPDSSGEGLF

Sequences:

>Translated_342_residues
MSVEHSPVDPSAEPPEKAEEAALRPGALAEFGGQQRVADQLGLVLAASKSRGTTPDHVLLSGPPGLGKTTLAMIIASEMS
APIRISSGPAIQHAGDLAAILSSLVPGEVFFLDEIHRMSKPAEEMLYLAMEDFRVDVVVGKGPGATAIPIEIPPFTLVGA
TTRAGLLPGPLRDRFGFTAQLDYYEVADLERIVTRSAGVIGVELAEGAAHTIASRSRGTPRIANRLLRRVRDWADVHHES
PVTPQGAETALDLYEVDPLGLDRLDRAVLHAVCLKFGGGPVGLSTLAISVGEEPQTVEEVAEPFLVRLGFLMRTPRGRVP
TDRAWRHLGLEPPPDSSGEGLF
>Mature_341_residues
SVEHSPVDPSAEPPEKAEEAALRPGALAEFGGQQRVADQLGLVLAASKSRGTTPDHVLLSGPPGLGKTTLAMIIASEMSA
PIRISSGPAIQHAGDLAAILSSLVPGEVFFLDEIHRMSKPAEEMLYLAMEDFRVDVVVGKGPGATAIPIEIPPFTLVGAT
TRAGLLPGPLRDRFGFTAQLDYYEVADLERIVTRSAGVIGVELAEGAAHTIASRSRGTPRIANRLLRRVRDWADVHHESP
VTPQGAETALDLYEVDPLGLDRLDRAVLHAVCLKFGGGPVGLSTLAISVGEEPQTVEEVAEPFLVRLGFLMRTPRGRVPT
DRAWRHLGLEPPPDSSGEGLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=319, Percent_Identity=53.9184952978056, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PROAC (Q6A8K7)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055867.1
- ProteinModelPortal:   Q6A8K7
- SMR:   Q6A8K7
- GeneID:   2932265
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA1160
- NMPDR:   fig|267747.1.peg.1144
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   PACN267747:PPA1160-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36406; Mature: 36275

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEHSPVDPSAEPPEKAEEAALRPGALAEFGGQQRVADQLGLVLAASKSRGTTPDHVLL
CCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHCCHHHHHHHHCEEEEECCCCCCCCCEEEE
SGPPGLGKTTLAMIIASEMSAPIRISSGPAIQHAGDLAAILSSLVPGEVFFLDEIHRMSK
ECCCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHCC
PAEEMLYLAMEDFRVDVVVGKGPGATAIPIEIPPFTLVGATTRAGLLPGPLRDRFGFTAQ
CHHHHHHHHHHCEEEEEEEECCCCCEEEEEECCCEEEECCCHHCCCCCCCHHHHCCCEEE
LDYYEVADLERIVTRSAGVIGVELAEGAAHTIASRSRGTPRIANRLLRRVRDWADVHHES
ECHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
PVTPQGAETALDLYEVDPLGLDRLDRAVLHAVCLKFGGGPVGLSTLAISVGEEPQTVEEV
CCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCHHHHHH
AEPFLVRLGFLMRTPRGRVPTDRAWRHLGLEPPPDSSGEGLF
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SVEHSPVDPSAEPPEKAEEAALRPGALAEFGGQQRVADQLGLVLAASKSRGTTPDHVLL
CCCCCCCCCCCCCCHHHHHHHCCCCHHHHHCCHHHHHHHHCEEEEECCCCCCCCCEEEE
SGPPGLGKTTLAMIIASEMSAPIRISSGPAIQHAGDLAAILSSLVPGEVFFLDEIHRMSK
ECCCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEHHHHHHHHCC
PAEEMLYLAMEDFRVDVVVGKGPGATAIPIEIPPFTLVGATTRAGLLPGPLRDRFGFTAQ
CHHHHHHHHHHCEEEEEEEECCCCCEEEEEECCCEEEECCCHHCCCCCCCHHHHCCCEEE
LDYYEVADLERIVTRSAGVIGVELAEGAAHTIASRSRGTPRIANRLLRRVRDWADVHHES
ECHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
PVTPQGAETALDLYEVDPLGLDRLDRAVLHAVCLKFGGGPVGLSTLAISVGEEPQTVEEV
CCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEECCCCCHHHHHH
AEPFLVRLGFLMRTPRGRVPTDRAWRHLGLEPPPDSSGEGLF
HHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA