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The map label for this gene is 50842555

Identifier: 50842555

GI number: 50842555

Start: 1172709

End: 1173926

Strand: Direct

Name: 50842555

Synonym: PPA1077

Alternate gene names: NA

Gene position: 1172709-1173926 (Clockwise)

Preceding gene: 50842554

Following gene: 50842556

Centisome position: 45.8

GC content: 60.67

Gene sequence:

>1218_bases
ATGAGGACTGGCAGGTCGCCACCGACACCCTCGACCAGGTGTGCCGTAGCACTGGTTTGCAGCTGGTCCCTGATCCGGGT
GGTGCGGCTTTCTATGGCCCGAAGGTCTCGGTGCAGGTTAGGGATGCCATCGGGCGTACCTGGCAGATGTCGACGATTCA
GTATGACTTTAACCAGCCTGAGCGGTTCGACTTGGAATACGCGGCTGCTGACGGCACCCATCAGCGTCCGATCATGCTGC
ACTCAGCCAAGTTGGGTAGTGTCGAGAGGTTTATTGGTGTGCTTACCGAGCATTACGCCGGTGCTTTCCCGGTATGGCTC
TCTCCGGTCCAGGTGCGCTTGGTGCCGGTGGCTGAGGCCTTTAACGACTACGTCACCGGGTTCGCAGAGGTGTTGGGTTC
CCGCGGGATTCGGGTCGAGACGGACCTGTCCTCGGACCGGTTTGGCAAGAAGATCCGCAACGCCTCTAAGGACAAGGTGC
CTTTCATCCTCATCGCGGGCGGTGAGGATGCCGAGGCTGGTGCCGTATCCTTCCGGCTGCGTGATGGCTCTCAGGTCAAT
GGCGTCGTCCTGGACGAGGCAGTGCGTATCATTGCAGCTTGGGACAGTCGGCACCGCAACGACGATCCGACTGCCGAGAC
GCTGCGCGGAGTCGTTGATGACTGAGGATTACCGTCTCGAGTTCGCCGAGGAACTGGTCGGGGTTCCGGATCCCTTCAGG
AGGTTCTGGACCCCGTATCGGATGGCGTATATCTCTGGTGAAAATAAGCCTCGAGGTAACCGGCCGGAGGATGGTTGTCC
CTTCTGTAGAGCCCCGCAGCGTAGCGACGAGGACGCCCTTATCGTCCACCGTGGCGAGCACTGCTACGTCATTATGAACC
TTTATCCCTACGGACCTGGGCACATGCTGGTATGCCCTTACCGCCACGTTGCTGGGTACGTCGATGCAACCCAAGACGAA
GTCGTCGAGATGGCCGAGCTCACCCAGGATGCCATCCGGACCCTCCAGGAGGTGTCCCGTCCACAAGGGTTCAACGTAGG
CATCAATCAGGGGGCATCCGGTGGTGCCGGGGTTGCCGCGCACCTGCATCAACACGTCATCCCGCGGTGGACCGGCGATA
CCAACTTTCTGCCCATCGTTGCCGGGGTCCGTGCTGTACCGCAATTGCTCGGCGATGGGCGCCAGATGCTTGCCGATGCG
TGGGTGGGTCATGCTTGA

Upstream 100 bases:

>100_bases
TTCCTGTCGATCCTGGCCGATTTTGGCCTCAATGACTTTTACCTCGAGCTGTCTACTCGTGAGAGCGACAGCGCGAAAAA
GGAGAAATTCATCGGTTCCG

Downstream 100 bases:

>100_bases
GCACTTCCGTGCTGGCTGGGCCAAGGTCATGAATCCCATTGCCGACGCCTTGCTGAGAGCCCATGTCACCCCTGACGTGG
TCACCTGGATCGGAACCATT

Product: putative HIT family protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRTGRSPPTPSTRCAVALVCSWSLIRVVRLSMARRSRCRLGMPSGVPGRCRRFSMTLTSLSGSTWNTRLLTAPISVRSCC
TQPSWVVSRGLLVCLPSITPVLSRYGSLRSRCAWCRWLRPLTTTSPGSQRCWVPAGFGSRRTCPRTGLARRSATPLRTRC
LSSSSRAVRMPRLVPYPSGCVMALRSMASSWTRQCVSLQLGTVGTATTIRLPRRCAESLMTEDYRLEFAEELVGVPDPFR
RFWTPYRMAYISGENKPRGNRPEDGCPFCRAPQRSDEDALIVHRGEHCYVIMNLYPYGPGHMLVCPYRHVAGYVDATQDE
VVEMAELTQDAIRTLQEVSRPQGFNVGINQGASGGAGVAAHLHQHVIPRWTGDTNFLPIVAGVRAVPQLLGDGRQMLADA
WVGHA

Sequences:

>Translated_405_residues
MRTGRSPPTPSTRCAVALVCSWSLIRVVRLSMARRSRCRLGMPSGVPGRCRRFSMTLTSLSGSTWNTRLLTAPISVRSCC
TQPSWVVSRGLLVCLPSITPVLSRYGSLRSRCAWCRWLRPLTTTSPGSQRCWVPAGFGSRRTCPRTGLARRSATPLRTRC
LSSSSRAVRMPRLVPYPSGCVMALRSMASSWTRQCVSLQLGTVGTATTIRLPRRCAESLMTEDYRLEFAEELVGVPDPFR
RFWTPYRMAYISGENKPRGNRPEDGCPFCRAPQRSDEDALIVHRGEHCYVIMNLYPYGPGHMLVCPYRHVAGYVDATQDE
VVEMAELTQDAIRTLQEVSRPQGFNVGINQGASGGAGVAAHLHQHVIPRWTGDTNFLPIVAGVRAVPQLLGDGRQMLADA
WVGHA
>Mature_405_residues
MRTGRSPPTPSTRCAVALVCSWSLIRVVRLSMARRSRCRLGMPSGVPGRCRRFSMTLTSLSGSTWNTRLLTAPISVRSCC
TQPSWVVSRGLLVCLPSITPVLSRYGSLRSRCAWCRWLRPLTTTSPGSQRCWVPAGFGSRRTCPRTGLARRSATPLRTRC
LSSSSRAVRMPRLVPYPSGCVMALRSMASSWTRQCVSLQLGTVGTATTIRLPRRCAESLMTEDYRLEFAEELVGVPDPFR
RFWTPYRMAYISGENKPRGNRPEDGCPFCRAPQRSDEDALIVHRGEHCYVIMNLYPYGPGHMLVCPYRHVAGYVDATQDE
VVEMAELTQDAIRTLQEVSRPQGFNVGINQGASGGAGVAAHLHQHVIPRWTGDTNFLPIVAGVRAVPQLLGDGRQMLADA
WVGHA

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 44821; Mature: 44821

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTGRSPPTPSTRCAVALVCSWSLIRVVRLSMARRSRCRLGMPSGVPGRCRRFSMTLTSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECC
SGSTWNTRLLTAPISVRSCCTQPSWVVSRGLLVCLPSITPVLSRYGSLRSRCAWCRWLRP
CCCCCCCEEEECCCHHHHHCCCCHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCC
LTTTSPGSQRCWVPAGFGSRRTCPRTGLARRSATPLRTRCLSSSSRAVRMPRLVPYPSGC
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHCCCCCEEECCCCCCCCCHH
VMALRSMASSWTRQCVSLQLGTVGTATTIRLPRRCAESLMTEDYRLEFAEELVGVPDPFR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHH
RFWTPYRMAYISGENKPRGNRPEDGCPFCRAPQRSDEDALIVHRGEHCYVIMNLYPYGPG
HHCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCC
HMLVCPYRHVAGYVDATQDEVVEMAELTQDAIRTLQEVSRPQGFNVGINQGASGGAGVAA
CEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
HLHQHVIPRWTGDTNFLPIVAGVRAVPQLLGDGRQMLADAWVGHA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRTGRSPPTPSTRCAVALVCSWSLIRVVRLSMARRSRCRLGMPSGVPGRCRRFSMTLTSL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEEEEEECC
SGSTWNTRLLTAPISVRSCCTQPSWVVSRGLLVCLPSITPVLSRYGSLRSRCAWCRWLRP
CCCCCCCEEEECCCHHHHHCCCCHHHHHCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCC
LTTTSPGSQRCWVPAGFGSRRTCPRTGLARRSATPLRTRCLSSSSRAVRMPRLVPYPSGC
CCCCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCHHHHHHHCCCCCEEECCCCCCCCCHH
VMALRSMASSWTRQCVSLQLGTVGTATTIRLPRRCAESLMTEDYRLEFAEELVGVPDPFR
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHH
RFWTPYRMAYISGENKPRGNRPEDGCPFCRAPQRSDEDALIVHRGEHCYVIMNLYPYGPG
HHCCHHEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCC
HMLVCPYRHVAGYVDATQDEVVEMAELTQDAIRTLQEVSRPQGFNVGINQGASGGAGVAA
CEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
HLHQHVIPRWTGDTNFLPIVAGVRAVPQLLGDGRQMLADAWVGHA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]