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The map label for this gene is hflX [H]

Identifier: 50842504

GI number: 50842504

Start: 1105133

End: 1106584

Strand: Direct

Name: hflX [H]

Synonym: PPA1021

Alternate gene names: 50842504

Gene position: 1105133-1106584 (Clockwise)

Preceding gene: 50842503

Following gene: 50842505

Centisome position: 43.16

GC content: 57.16

Gene sequence:

>1452_bases
GTGAGCGAGATCGAACAAATCGATAACGAGCGCGAAGACGCGCTGAAGAACAACAACGGTTTTAGCGAGGATCAGAGTGA
CTACGACGGTGACCAATTTGATCTGGATGCACGCCTATCGCTGACACGCGTGCCAGGTATGTCAACTGATCTGTCGGATA
TTTCCGAGGTTGAGTACCGTCAACTGAGGCTGGAACGAGTGGTGCTGTGTTCGGTGTGGACTCAGGGAACTGCCGCAGAC
GCCGAGAACGCTATGGCGGAGCTGAAAGCCCTTGCTGAAACGGCGGGATCTCAGGTACTCGAAGCTGTCATGCAACATCG
GACTACCCCGGATCCGGCGACGTACATTGGTTCGGGCAAGGTGGCAGAGCTTGCCGAGGTGGTGTGGGCGACTGGCGCCG
ATACTGTCATTTGTGATGGTGAACTTGACGCCGCTCAGTTGCGCAACCTCGAGGATCGGGTCAAGGTCAAAGTTGTGGAC
CGGACGGCCCTGATTCTCGACATATTCGCTCAACATGCGCGCAGCGTTGAGGGTCGTACTCAGGTGGAGCTGGCCCAGCT
TAATTATCTCAAGCAGAGATTGCGTGGTTGGGGCGGCAATCTCTCGCGTCAGACTGGTGGACGAGCCGCCGGAGGTGCTG
GTATCGGTGGTCGTGGTCCCGGTGAGACCCGTATCGAGACTGACCGTCGACGTATTAGCCATCGGATTGCGGTGTTGCGT
CGTCGTCTCACGCACATCGAGTCCACCCGTGCCTCCAAACGGGCCGATCGCATCCGAAACAAGGTGCCATCAGTGGCCAT
CGTCGGGTACACCAACGCTGGTAAGTCTTCCTTGCTCAACAGGCTTACCCGCGCCGGGGTACTCGTCGAGAATGCTCTGT
TTGCAACCCTTGACCCCACGACTCGACGCGCCACCACCTCCGACGGTCGGGTCTACACCCTCACTGACACGGTGGGATTT
GTTCGACACTTGCCGCACGACCTCGTCGAGGCCTTTGCATCTACTCTGGAGGAGACGGCGATGGCCGATGTGCTCCTCCA
CGTTGTGGATGCAGATGATCCAGATCCACTCGGCCAGGTCGACGCAGTACGCGGGGTGCTGTCGGGGATTGGGGCCAGTA
ATATTCCTGAGATTCTCGTCCTTAACAAGATTGATCGTCTTAGCGATGAAACCATCTTGACCTTGCGCTCTACCTTCCCG
GGGGCTTACTTAGTCTCTGCTCATACAGGTGAAGGAATCGATAAGCTTGTCGAGGCCATCGAGGCCGGACTTCCCATACC
TTCCCAGCGCGTCGACGTCGTTATTCCTTATGCGCGTGGGGATCTTATGGACAAGATTCACCACAACGGAACTATCGGAC
TCATTGATCACACTGCTGATGGCACTCATGTCGTCGCTCACCTTCACCCTGCTCTAGCGGCCGAGGTCGAAGAGGCTTGT
GATGGGGTCTGA

Upstream 100 bases:

>100_bases
TCTGCCGAATGGATGAGAGGGCGAACACGCTCTTGTCAACCTGTCGGAACGTCCTCCTACACTTAGCGCGATGGCATTGG
GGCGTGAGGATGGGTACCGG

Downstream 100 bases:

>100_bases
GCCGGCAGACGTCAGTCAGATGTGTCGTGACCTGCTCAGCACTGCCGTCTCTGAGATGGGTGGTCAAGAGAGGCCGGGCC
AAGTCGCGATGGCTAAAGCT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MSEIEQIDNEREDALKNNNGFSEDQSDYDGDQFDLDARLSLTRVPGMSTDLSDISEVEYRQLRLERVVLCSVWTQGTAAD
AENAMAELKALAETAGSQVLEAVMQHRTTPDPATYIGSGKVAELAEVVWATGADTVICDGELDAAQLRNLEDRVKVKVVD
RTALILDIFAQHARSVEGRTQVELAQLNYLKQRLRGWGGNLSRQTGGRAAGGAGIGGRGPGETRIETDRRRISHRIAVLR
RRLTHIESTRASKRADRIRNKVPSVAIVGYTNAGKSSLLNRLTRAGVLVENALFATLDPTTRRATTSDGRVYTLTDTVGF
VRHLPHDLVEAFASTLEETAMADVLLHVVDADDPDPLGQVDAVRGVLSGIGASNIPEILVLNKIDRLSDETILTLRSTFP
GAYLVSAHTGEGIDKLVEAIEAGLPIPSQRVDVVIPYARGDLMDKIHHNGTIGLIDHTADGTHVVAHLHPALAAEVEEAC
DGV

Sequences:

>Translated_483_residues
MSEIEQIDNEREDALKNNNGFSEDQSDYDGDQFDLDARLSLTRVPGMSTDLSDISEVEYRQLRLERVVLCSVWTQGTAAD
AENAMAELKALAETAGSQVLEAVMQHRTTPDPATYIGSGKVAELAEVVWATGADTVICDGELDAAQLRNLEDRVKVKVVD
RTALILDIFAQHARSVEGRTQVELAQLNYLKQRLRGWGGNLSRQTGGRAAGGAGIGGRGPGETRIETDRRRISHRIAVLR
RRLTHIESTRASKRADRIRNKVPSVAIVGYTNAGKSSLLNRLTRAGVLVENALFATLDPTTRRATTSDGRVYTLTDTVGF
VRHLPHDLVEAFASTLEETAMADVLLHVVDADDPDPLGQVDAVRGVLSGIGASNIPEILVLNKIDRLSDETILTLRSTFP
GAYLVSAHTGEGIDKLVEAIEAGLPIPSQRVDVVIPYARGDLMDKIHHNGTIGLIDHTADGTHVVAHLHPALAAEVEEAC
DGV
>Mature_482_residues
SEIEQIDNEREDALKNNNGFSEDQSDYDGDQFDLDARLSLTRVPGMSTDLSDISEVEYRQLRLERVVLCSVWTQGTAADA
ENAMAELKALAETAGSQVLEAVMQHRTTPDPATYIGSGKVAELAEVVWATGADTVICDGELDAAQLRNLEDRVKVKVVDR
TALILDIFAQHARSVEGRTQVELAQLNYLKQRLRGWGGNLSRQTGGRAAGGAGIGGRGPGETRIETDRRRISHRIAVLRR
RLTHIESTRASKRADRIRNKVPSVAIVGYTNAGKSSLLNRLTRAGVLVENALFATLDPTTRRATTSDGRVYTLTDTVGFV
RHLPHDLVEAFASTLEETAMADVLLHVVDADDPDPLGQVDAVRGVLSGIGASNIPEILVLNKIDRLSDETILTLRSTFPG
AYLVSAHTGEGIDKLVEAIEAGLPIPSQRVDVVIPYARGDLMDKIHHNGTIGLIDHTADGTHVVAHLHPALAAEVEEACD
GV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=32.8638497652582, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=32.8638497652582, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=32.8638497652582, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=32.8638497652582, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI310133116, Length=221, Percent_Identity=32.579185520362, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI310133118, Length=237, Percent_Identity=32.4894514767932, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1790615, Length=388, Percent_Identity=45.8762886597938, Blast_Score=297, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17561038, Length=342, Percent_Identity=30.7017543859649, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24650079, Length=399, Percent_Identity=29.8245614035088, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52299; Mature: 52168

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIEQIDNEREDALKNNNGFSEDQSDYDGDQFDLDARLSLTRVPGMSTDLSDISEVEYR
CCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
QLRLERVVLCSVWTQGTAADAENAMAELKALAETAGSQVLEAVMQHRTTPDPATYIGSGK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCC
VAELAEVVWATGADTVICDGELDAAQLRNLEDRVKVKVVDRTALILDIFAQHARSVEGRT
HHHHHHHHHHCCCCEEEECCCCCHHHHHCCHHHEEEEEECHHHHHHHHHHHHHHCCCCCH
QVELAQLNYLKQRLRGWGGNLSRQTGGRAAGGAGIGGRGPGETRIETDRRRISHRIAVLR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RRLTHIESTRASKRADRIRNKVPSVAIVGYTNAGKSSLLNRLTRAGVLVENALFATLDPT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCC
TRRATTSDGRVYTLTDTVGFVRHLPHDLVEAFASTLEETAMADVLLHVVDADDPDPLGQV
CCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DAVRGVLSGIGASNIPEILVLNKIDRLSDETILTLRSTFPGAYLVSAHTGEGIDKLVEAI
HHHHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHH
EAGLPIPSQRVDVVIPYARGDLMDKIHHNGTIGLIDHTADGTHVVAHLHPALAAEVEEAC
HCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHH
DGV
CCC
>Mature Secondary Structure 
SEIEQIDNEREDALKNNNGFSEDQSDYDGDQFDLDARLSLTRVPGMSTDLSDISEVEYR
CHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHH
QLRLERVVLCSVWTQGTAADAENAMAELKALAETAGSQVLEAVMQHRTTPDPATYIGSGK
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCC
VAELAEVVWATGADTVICDGELDAAQLRNLEDRVKVKVVDRTALILDIFAQHARSVEGRT
HHHHHHHHHHCCCCEEEECCCCCHHHHHCCHHHEEEEEECHHHHHHHHHHHHHHCCCCCH
QVELAQLNYLKQRLRGWGGNLSRQTGGRAAGGAGIGGRGPGETRIETDRRRISHRIAVLR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
RRLTHIESTRASKRADRIRNKVPSVAIVGYTNAGKSSLLNRLTRAGVLVENALFATLDPT
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCEEEEECCC
TRRATTSDGRVYTLTDTVGFVRHLPHDLVEAFASTLEETAMADVLLHVVDADDPDPLGQV
CCCCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
DAVRGVLSGIGASNIPEILVLNKIDRLSDETILTLRSTFPGAYLVSAHTGEGIDKLVEAI
HHHHHHHHHCCCCCCCCEEEEHHHHHCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHHH
EAGLPIPSQRVDVVIPYARGDLMDKIHHNGTIGLIDHTADGTHVVAHLHPALAAEVEEAC
HCCCCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHHH
DGV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]