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The map label for this gene is pyrK [H]

Identifier: 50842484

GI number: 50842484

Start: 1086166

End: 1086960

Strand: Direct

Name: pyrK [H]

Synonym: PPA1001

Alternate gene names: 50842484

Gene position: 1086166-1086960 (Clockwise)

Preceding gene: 50842483

Following gene: 50842485

Centisome position: 42.42

GC content: 60.88

Gene sequence:

>795_bases
ATGACAAAGACGACTGGGTTTCGTCGTGGCCCACAGATGATGCGACTTGCCGACCGTCACGAGATTGCCACCGGAATATA
TTCGGTGCGACTCATCCCTCATGAACCTGTGCCACACGTTGTACCAGGGACTTTTCTTGATCTGTTGCTCGGTGGTGGAC
ACGTGCTGCGCCGGCCATTGTCTATTGCGGACGCCGATGACGAGGGATACACCCTTGTCTTTCGGGTGGTAGGGAAGGGA
ACCGACACGCTCTCGGTAAAGCCGATCGGGGCAGAGGTAGACGTCTTGGGTCCGCTCGGTCATGGGTTCGACGTTGACGC
GGTTCAGCCCGAGGGGCGGGCCCTGCTTATTGGTGGAGGAGTTGGGATCCCGCCGCTGTACTTGTTGGGACGGCGACTTG
TTGAACGTGGCGTCGAGGTGCAGTTCCGGCTGGGATTCCGCGATCGAAACGACATCTTTTGGGCTGAGCGCTTCGGCCAG
CTCGGTGAGGTTCTCGTCTCCACTGACGACGGGTCGGTCGGGACGAAGGGGACTGTCGCTCAGATTGCCGAGACTGACGA
GGCTCGTCGTTTTGTCCCCGATCTCGTGCAGGCCTGCGGGCCTCTCCCCATGCTGAGATGGGTGAAGTCTGCACTAGCGC
CGACCGTGCGTACCCAGCTATCTCTGGAGGAGAGAATGGCTTGCGGTGTAGGCGCGTGCTACGCCTGCGTCGTCGGTGAT
GCCCGAGACCCCGATCACCAGTTTCGGGTGTGCTTCGACGGTCCCGTGCTCGCGGCCGAGGAGGTTCTGCTATGA

Upstream 100 bases:

>100_bases
AAGCCATCGCTCGTGGCATCCCACTTTTCACCTCGCTGGATACCGCTGCGGCGATTTGCCGGGTCATGGAATCGCGGGTC
TTCTCGACGGAGTCGATCTG

Downstream 100 bases:

>100_bases
CTAGATTGGCCGTGTCCCTTCCGGGCCTGAACCTTAAGAACCCGATCATGCCCGCCAGCGGGTGTTTTGGTTTTGGCGCC
GAGTATGCGGAGTACTACGA

Product: dihydroorotate dehydrogenase electron transfer subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTKTTGFRRGPQMMRLADRHEIATGIYSVRLIPHEPVPHVVPGTFLDLLLGGGHVLRRPLSIADADDEGYTLVFRVVGKG
TDTLSVKPIGAEVDVLGPLGHGFDVDAVQPEGRALLIGGGVGIPPLYLLGRRLVERGVEVQFRLGFRDRNDIFWAERFGQ
LGEVLVSTDDGSVGTKGTVAQIAETDEARRFVPDLVQACGPLPMLRWVKSALAPTVRTQLSLEERMACGVGACYACVVGD
ARDPDHQFRVCFDGPVLAAEEVLL

Sequences:

>Translated_264_residues
MTKTTGFRRGPQMMRLADRHEIATGIYSVRLIPHEPVPHVVPGTFLDLLLGGGHVLRRPLSIADADDEGYTLVFRVVGKG
TDTLSVKPIGAEVDVLGPLGHGFDVDAVQPEGRALLIGGGVGIPPLYLLGRRLVERGVEVQFRLGFRDRNDIFWAERFGQ
LGEVLVSTDDGSVGTKGTVAQIAETDEARRFVPDLVQACGPLPMLRWVKSALAPTVRTQLSLEERMACGVGACYACVVGD
ARDPDHQFRVCFDGPVLAAEEVLL
>Mature_263_residues
TKTTGFRRGPQMMRLADRHEIATGIYSVRLIPHEPVPHVVPGTFLDLLLGGGHVLRRPLSIADADDEGYTLVFRVVGKGT
DTLSVKPIGAEVDVLGPLGHGFDVDAVQPEGRALLIGGGVGIPPLYLLGRRLVERGVEVQFRLGFRDRNDIFWAERFGQL
GEVLVSTDDGSVGTKGTVAQIAETDEARRFVPDLVQACGPLPMLRWVKSALAPTVRTQLSLEERMACGVGACYACVVGDA
RDPDHQFRVCFDGPVLAAEEVLL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 28562; Mature: 28431

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTTGFRRGPQMMRLADRHEIATGIYSVRLIPHEPVPHVVPGTFLDLLLGGGHVLRRPL
CCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHCCC
SIADADDEGYTLVFRVVGKGTDTLSVKPIGAEVDVLGPLGHGFDVDAVQPEGRALLIGGG
CEECCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEECC
VGIPPLYLLGRRLVERGVEVQFRLGFRDRNDIFWAERFGQLGEVLVSTDDGSVGTKGTVA
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHH
QIAETDEARRFVPDLVQACGPLPMLRWVKSALAPTVRTQLSLEERMACGVGACYACVVGD
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHEEECC
ARDPDHQFRVCFDGPVLAAEEVLL
CCCCCCCEEEEECCCCHHHHHHCC
>Mature Secondary Structure 
TKTTGFRRGPQMMRLADRHEIATGIYSVRLIPHEPVPHVVPGTFLDLLLGGGHVLRRPL
CCCCCCCCCHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHCCC
SIADADDEGYTLVFRVVGKGTDTLSVKPIGAEVDVLGPLGHGFDVDAVQPEGRALLIGGG
CEECCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEECC
VGIPPLYLLGRRLVERGVEVQFRLGFRDRNDIFWAERFGQLGEVLVSTDDGSVGTKGTVA
CCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCHHH
QIAETDEARRFVPDLVQACGPLPMLRWVKSALAPTVRTQLSLEERMACGVGACYACVVGD
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHEEECC
ARDPDHQFRVCFDGPVLAAEEVLL
CCCCCCCEEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]