| Definition | Propionibacterium acnes KPA171202, complete genome. |
|---|---|
| Accession | NC_006085 |
| Length | 2,560,265 |
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The map label for this gene is aceE
Identifier: 50842473
GI number: 50842473
Start: 1072364
End: 1075117
Strand: Direct
Name: aceE
Synonym: PPA0989
Alternate gene names: 50842473
Gene position: 1072364-1075117 (Clockwise)
Preceding gene: 50842471
Following gene: 50842474
Centisome position: 41.88
GC content: 60.93
Gene sequence:
>2754_bases GTGATCCCACGCGAAGAACGCGGACCAGTCCTCAACGGACTTCCGACAACCCTGCCTGACGTCGATCCCGAGGAGACTCA GGAGTGGATCGAGTCCCTCGACAAGATGGTCGAGACTGATGGTCCGAATCGTGCCCGGATCGTGCTGCTCAAGATGTTGG AGCGGGCTCGTAGCCACAGTCGTCTCGGGCTGTCAGCGCTCACCTCCACCGACTACATCAACACCATTGCAGCCGAGGAC GAGGAAGAATACCCCGGCGACGCCGAGATCGAGCGGAACATCCGTCGTTTGCTGCGCTGGAATTCCGCCATTACCGTGCA TCGCGCGCAGCGTCCCGGTATTGGCGTCGGCGGTCATATCTCCACCTATGCCTCTGCCGTGACCCTCTACGAGGTCGGTC AGAACCACTTCTGGCGCGGGCAGGACGCCCCCGGCGGCGGTGACCAAGTTTTCTTCCAGGGGCACGCCGCGCCCGGTATG TACGCTCGCGCGTTCTTGGAGGGGCGTCTCAGCGAGGACGATCTCGATGGGTTCCGTCAGGAGAAGTCGAAGGCCGGGCA TGGTCTACCCTCTTACCCGCACCCTCGCATGTTGCCCGACTTCTGGCAGTTCCCGACGGTGTCGATGGGTCTGGGCCCGA TGAATTCCATTTACCAGGCGTCTATGAATAAGTACCTCACCAATCGCGGTGTCAAGGACTGCGCAGATCAGCACGTGTGG GCTTTCCTTGGCGACGGTGAGATGGACGAGCCGGAGTCGCGCGGATTCCTGCAGGTCGCTGCCAACGAGGAGCTCGACAA CCTCACCTTCGTCATCAACTGCAACCTGCAGCGTCTAGACGGGCCGGTGCGTGGCAACGGCAAGATTGTCCAGGAACTTG AGGCTGTCTTCCGTGGTGCTGGCTGGAACGTCATCAAGGTCATTTGGGGATCCGGCTGGGACCCGTTGCTGCAGGCAGAC CGTGACGGTGCCCTCGTTGATATCATGAACAACACCCGTGATGGCGACTACCAAACCTTTAAGGCCAACGACGGCGCCTA TGTCCGCGAGCACTTCTTTGGCCGCGACCCGCGCACTGCCAAGATGGTCGACAAGTGGACTGACGAACAGATTTGGGCGT TACGCCGTGGCGGTCACGACTACCGCAAGATTTACAACGCCTACAAGGCGGCTACGCAGTTCAAGGGAGCGCCGACCGTG GTGCTTGCCTGCACTATTAAAGGTTACGATCTTGGTACTCACTTTGCGGGCCGCAACGCTACCCACCAGATGAAGAAGCT GGCCCTTGAGGACCTCAAGCAGTTCCGCGATCGTCTCGAAATTCCGATTTCGGACAAGGTGCTGGAGGCCGACCCCTACC GTGCTCCCTACTTCCATCCCGGAGCCGATGACGAGCGCATCCAGTACCTCATGGAGCGTCGTCGCGCTCTCGGCGGTTTC GTGCCGGAGCGCCGTACGAGGCACACGCCACTACCCATCCCGGCGCAGAAGGCCTTCGATGGTGTCAAGCGTGGGTCGGG CAAACAGGAGGTCGCCACCACGATGGCCTTCGTGCGTCTGCTCAAGGACCTTATGCGCGACAAGAATTTCGCTCCGCACG TCGTCCCGATCATTCCTGACGAGGCCCGTACCTTTGGCATGGACTCGTTCTTCCCGACGATCAAGATCTACAATCCTCAC GGCCAGAACTACACCCCTGTCGACCACGAGCTCATGCTCAGCTACCGCGAGGCCAAGAACGGGCAGATCATTCACACTGG CATCAATGAGGCTGGTTCGGCGGCTGCTTTCATTGCCGCAGGCTCGGCATACTCCACTCAGGGCGTGCCGATGGTGCCGA TCTACCTGTTCTACTCGATGTTCGGGTTCCAGCGTACCGGTGATTCTTTCTGGGCAGCTGGTGATCAGATGACGAGGGGA TTCATTATTGGCGCCACTGCCGGACGCACCACGCTGACCGGTGAGGGCACCCAGCACATGGATGGCCATTCGCCGGTTCT GGCTGCGACTAACCCAGCTGTCATCTCCTACGATCCGGCTTATTCTTACGAGATCTCCCACATTGTTCAGGCAGGTCTGG AGCACATGTACGGCGAGAACGCCGAAGACGTCATGTACTACCTGACGGTGTACAACGAGCCGATCGTCCAGCCGGCTGAG CCAGAGGGCGTTGACGCCGAGGGCATCGTCAAGGGCATGTACCTGCTCTCGAAGGGCTCCTTTGAGGGCGTCGGCGAGGA TGCCCGCCGCGTTCAGCTGCTGGCCTCCGGCGTCGCCGTGCCGTGGGCCATTGAGGCTCAGCAGCTCCTTAAGGGTGACT TTGGCGTTGTTGCCGACGTGTGGTCGGTGACGTCGTGGAACAACCTACGTCGTGACGCTATGGAGGCCGAGGAACAGACT TTCCTACACCCCGAACAGGGCAGGCGCACCCCGTATATCACCCAATGCCTGGCCGACGCCCCTGGTCCAGTCGTTGCGAC CACCGATTACACGTGTCAGGTGCCCGATCAGATCGCCCAGTGGGTGCCGGGGGATTATGCCTCCTTAGGTGCTGACGGAT TCGGGTTCTCCGACACCCGTGCGGCAGCGCGCCGATTCTTCCACATCGATGGACCGTCCATGACAGTGCGTGCCCTCCAG ATGCTCGTCGAGCGTGGTGAGGTTCCCGAGGACTGGCCTGCCAAGGCTGCCGAGAAGTACGACCTCCTCAACGTCAACGC GGGGGCGTCCGGTAACGCTGGTGGCGACGCCTGA
Upstream 100 bases:
>100_bases ACGACACAATAAGTTCACGGCGGGCCCTCGGGCTGCCACCTTGAACCGTCACCGGTGATGTCGCCGGTTGTGCGTCGCTG TCGATGAGAAAGGACCCGGC
Downstream 100 bases:
>100_bases TCGATAGACCGTCGAATAACCGGGGCATTCCATGATGTGGGCTGCCCCGGTTTTCGTTGAAGTCCGTTGCCTCCGCCATA CTCCTGCTAGCCTTTTTAGC
Product: pyruvate dehydrogenase subunit E1
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 917; Mature: 917
Protein sequence:
>917_residues MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHSRLGLSALTSTDYINTIAAED EEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHISTYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGM YARAFLEGRLSEDDLDGFRQEKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMNSIYQASMNKYLTNRGVKDCADQHVW AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGAGWNVIKVIWGSGWDPLLQAD RDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTAKMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTV VLACTIKGYDLGTHFAGRNATHQMKKLALEDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPDEARTFGMDSFFPTIKIYNPH GQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAAGSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRG FIIGATAGRTTLTGEGTQHMDGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADVWSVTSWNNLRRDAMEAEEQT FLHPEQGRRTPYITQCLADAPGPVVATTDYTCQVPDQIAQWVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQ MLVERGEVPEDWPAKAAEKYDLLNVNAGASGNAGGDA
Sequences:
>Translated_917_residues MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHSRLGLSALTSTDYINTIAAED EEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHISTYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGM YARAFLEGRLSEDDLDGFRQEKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMNSIYQASMNKYLTNRGVKDCADQHVW AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGAGWNVIKVIWGSGWDPLLQAD RDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTAKMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTV VLACTIKGYDLGTHFAGRNATHQMKKLALEDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPDEARTFGMDSFFPTIKIYNPH GQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAAGSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRG FIIGATAGRTTLTGEGTQHMDGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADVWSVTSWNNLRRDAMEAEEQT FLHPEQGRRTPYITQCLADAPGPVVATTDYTCQVPDQIAQWVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQ MLVERGEVPEDWPAKAAEKYDLLNVNAGASGNAGGDA >Mature_917_residues MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHSRLGLSALTSTDYINTIAAED EEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHISTYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGM YARAFLEGRLSEDDLDGFRQEKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMNSIYQASMNKYLTNRGVKDCADQHVW AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGAGWNVIKVIWGSGWDPLLQAD RDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTAKMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTV VLACTIKGYDLGTHFAGRNATHQMKKLALEDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPDEARTFGMDSFFPTIKIYNPH GQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAAGSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRG FIIGATAGRTTLTGEGTQHMDGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADVWSVTSWNNLRRDAMEAEEQT FLHPEQGRRTPYITQCLADAPGPVVATTDYTCQVPDQIAQWVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQ MLVERGEVPEDWPAKAAEKYDLLNVNAGASGNAGGDA
Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge
COG id: COG2609
COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=50.6214689265537, Blast_Score=908, Evalue=0.0,
Paralogues:
None
Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004660 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005474 [H]
Pfam domain/function: PF00456 Transketolase_N [H]
EC number: =1.2.4.1 [H]
Molecular weight: Translated: 101723; Mature: 101723
Theoretical pI: Translated: 5.27; Mature: 5.27
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHS CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC RLGLSALTSTDYINTIAAEDEEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHI CCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH STYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGRLSEDDLDGFRQ HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH EKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMNSIYQASMNKYLTNRGVKDCADQHVW HHHHCCCCCCCCCCCCCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHHCCHHHHHCCCEE AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGA EEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCC GWNVIKVIWGSGWDPLLQADRDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTA CCEEEEEEECCCCCHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCHH KMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTVVLACTIKGYDLGTHFAGRNA HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCH THQMKKLALEDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF HHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPD CCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC EARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAA CHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEE GSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRGFIIGATAGRTTLTGEGTQHM CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCEEECCCCCCCC DGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE CCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCC PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADV CCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHH WSVTSWNNLRRDAMEAEEQTFLHPEQGRRTPYITQCLADAPGPVVATTDYTCQVPDQIAQ HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEECCCEEECHHHHHH WVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQMLVERGEVPEDWPAKAAEKY HCCCCHHHCCCCCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHCCC DLLNVNAGASGNAGGDA CEEEECCCCCCCCCCCC >Mature Secondary Structure MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHS CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHC RLGLSALTSTDYINTIAAEDEEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHI CCCHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCH STYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGRLSEDDLDGFRQ HHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCHHHHHHHH EKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMNSIYQASMNKYLTNRGVKDCADQHVW HHHHCCCCCCCCCCCCCCCHHHCCCCCEECCCCHHHHHHHHHHHHHHHCCHHHHHCCCEE AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGA EEECCCCCCCCCCCCEEEEECCCCCCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCC GWNVIKVIWGSGWDPLLQADRDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTA CCEEEEEEECCCCCHHHHCCCCCCEEEECCCCCCCCEEEEECCCCCHHHHHHCCCCCCHH KMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTVVLACTIKGYDLGTHFAGRNA HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCH THQMKKLALEDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF HHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPD CCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC EARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAA CHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEE GSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRGFIIGATAGRTTLTGEGTQHM CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCEEEEECCCCEEECCCCCCCC DGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE CCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCCCCCC PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADV CCCCCHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHH WSVTSWNNLRRDAMEAEEQTFLHPEQGRRTPYITQCLADAPGPVVATTDYTCQVPDQIAQ HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEECCCEEECHHHHHH WVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQMLVERGEVPEDWPAKAAEKY HCCCCHHHCCCCCCCCCHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCHHHHCCC DLLNVNAGASGNAGGDA CEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA