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The map label for this gene is bioD [H]

Identifier: 50842452

GI number: 50842452

Start: 1052814

End: 1053518

Strand: Direct

Name: bioD [H]

Synonym: PPA0968

Alternate gene names: 50842452

Gene position: 1052814-1053518 (Clockwise)

Preceding gene: 50842451

Following gene: 50842453

Centisome position: 41.12

GC content: 60.43

Gene sequence:

>705_bases
ATGAACATTACCGATCTCAACGGAATTGTCATCGTTACGGGAACTGACACCGACGTCGGCAAGACAGTCACTACTGCGGT
CATCGCCTCAGCACTCAAGCAATCTGGCAAAGATGTCACCATCATCAAGCCGTACCAGACCGGTCTGGATCACGATGAGC
CTGGCGACGTTCACGACGCTGGACGGCTCGCCAGCATTGACGCCGACAACGTGCTGGAGTATGTGCGCTGCCCCGAACCG
CTGGCCCCGACCACGTCGGCTGCCCGAGCTGGTATGACCATTCCCTCGATCGAGGAAGTCGCAACCCGCATCCTCGTCGA
CTCCGACGGCCATGACGCCACCCTCGTCGAAGGAGCAGGCGGCATCCTCGTTGGTTTGGACAATGACGGGTCTGGAGTCC
TTGACCTTATGGATGCTCTTACCCGGCGTGGGCACGAGCCCCACGTCATCGTCGTCACTCGCTCAGTGCTCGGTACCCTC
AACCACACTGGTTTGACTTGTAATGCCATCCGCGATCGGGGGCATCAGGTCGACGCTATCGTCATCGGCTCGTGGCCGGA
CCGGCCCGACCTTGCCGAGAGGTGCAACCTCGAAGAAATCGAGGATGCCGCCGGAGCTCCGTTGGTCGGAGTCATTCCCG
CTGGCATAGGTAAAGACCCCGAAGCCGTCCAGCAGACGGCCCGGAACCTTGGAGAGACTCAGTGA

Upstream 100 bases:

>100_bases
GTACCAACGATGATCTGGAGGCCATGGCCGCTGGGATGCGTGCCGTTGTCATAGATCAACTTGATGCTGCTCAGGACAAT
ACCGATTATCGGAAGGAATC

Downstream 100 bases:

>100_bases
GCACAACCCTCGCCCCTGACTCCCAGTTGAAGGACCTGGGCTACCAGCCCAGCCTCAACCGTCAGCTACCCTTTGGCTCG
TTATTGGTCTATGGGCTGCT

Product: dethiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNITDLNGIVIVTGTDTDVGKTVTTAVIASALKQSGKDVTIIKPYQTGLDHDEPGDVHDAGRLASIDADNVLEYVRCPEP
LAPTTSAARAGMTIPSIEEVATRILVDSDGHDATLVEGAGGILVGLDNDGSGVLDLMDALTRRGHEPHVIVVTRSVLGTL
NHTGLTCNAIRDRGHQVDAIVIGSWPDRPDLAERCNLEEIEDAAGAPLVGVIPAGIGKDPEAVQQTARNLGETQ

Sequences:

>Translated_234_residues
MNITDLNGIVIVTGTDTDVGKTVTTAVIASALKQSGKDVTIIKPYQTGLDHDEPGDVHDAGRLASIDADNVLEYVRCPEP
LAPTTSAARAGMTIPSIEEVATRILVDSDGHDATLVEGAGGILVGLDNDGSGVLDLMDALTRRGHEPHVIVVTRSVLGTL
NHTGLTCNAIRDRGHQVDAIVIGSWPDRPDLAERCNLEEIEDAAGAPLVGVIPAGIGKDPEAVQQTARNLGETQ
>Mature_234_residues
MNITDLNGIVIVTGTDTDVGKTVTTAVIASALKQSGKDVTIIKPYQTGLDHDEPGDVHDAGRLASIDADNVLEYVRCPEP
LAPTTSAARAGMTIPSIEEVATRILVDSDGHDATLVEGAGGILVGLDNDGSGVLDLMDALTRRGHEPHVIVVTRSVLGTL
NHTGLTCNAIRDRGHQVDAIVIGSWPDRPDLAERCNLEEIEDAAGAPLVGVIPAGIGKDPEAVQQTARNLGETQ

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324385, Length=175, Percent_Identity=32.5714285714286, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24430; Mature: 24430

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITDLNGIVIVTGTDTDVGKTVTTAVIASALKQSGKDVTIIKPYQTGLDHDEPGDVHDA
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCC
GRLASIDADNVLEYVRCPEPLAPTTSAARAGMTIPSIEEVATRILVDSDGHDATLVEGAG
CCEEECCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHEECCCCCCEEEEECCC
GILVGLDNDGSGVLDLMDALTRRGHEPHVIVVTRSVLGTLNHTGLTCNAIRDRGHQVDAI
EEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCEEEHHHHCCCCEEEEE
VIGSWPDRPDLAERCNLEEIEDAAGAPLVGVIPAGIGKDPEAVQQTARNLGETQ
EECCCCCCCCHHHHCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNITDLNGIVIVTGTDTDVGKTVTTAVIASALKQSGKDVTIIKPYQTGLDHDEPGDVHDA
CCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHCCCCCCCCCCCCCC
GRLASIDADNVLEYVRCPEPLAPTTSAARAGMTIPSIEEVATRILVDSDGHDATLVEGAG
CCEEECCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHEECCCCCCEEEEECCC
GILVGLDNDGSGVLDLMDALTRRGHEPHVIVVTRSVLGTLNHTGLTCNAIRDRGHQVDAI
EEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCCEEEHHHHCCCCEEEEE
VIGSWPDRPDLAERCNLEEIEDAAGAPLVGVIPAGIGKDPEAVQQTARNLGETQ
EECCCCCCCCHHHHCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA