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The map label for this gene is hrdD [H]

Identifier: 50842442

GI number: 50842442

Start: 1041754

End: 1042566

Strand: Direct

Name: hrdD [H]

Synonym: PPA0958

Alternate gene names: 50842442

Gene position: 1041754-1042566 (Clockwise)

Preceding gene: 50842441

Following gene: 50842443

Centisome position: 40.69

GC content: 58.67

Gene sequence:

>813_bases
ATGAGATACACGGATTTCATCGACGGCGTCGAAATCTTGGATCCTGCGGAGGAGCACGATCTGTTTCGCAGGCTCGATGC
TGGTGCCATTGCTGATGCTATTCTCGCTGGGCACTTCCTGGCAGCAGTCCCGGTCAGTGAGGCAGAGCTGCGCAGGATCT
CCGACGACGGAGTGGGCGCCAGACAAACGCTGTGGCGTCAAATGTTGGCGATCGTCTTGACCCAGGCTCGTCAGGCGGCT
GTGTCCTACCGGTGCAGCGTCGAGGACCTTATCCAAGCTGGCTGCATCGGATTGGGAGAGGCTATCGAGAGGTACGACGT
GCGTCGCGGAGCACGGTTTTCTACCGTTGCCTGGACGTGGATTCGTCGTCGCATCGGTGAAGAGGTTGTTCGATTAAGCG
GGGCCAGATCGCGGTCAGTGATGCGAGAGGCGGCGGAGGTTGCTCGTATCGAAGAGGAGCTGACGGCACGCTGGCAAAGT
GTGCCCAGTAGTGATGCGATCGCGGCACGGATGGGCAAGGACGTTATGTGGGTGGAGAAGAGGAGGGTCGAATGTTGGGA
GGTAGAAACCAGTTTTTTCGAGCAGGTGGCTGTTGTTCAGAAAAGTTGCGACGATCCCGAGTCTGGGCTCATTGGCCTGC
TGACGGGTCAGGAGAGACGCATCGTGGAGCTGAGGCACGGTTTTGAAGGTGAGCCTATGACGATCACTGCAGTTGCCCAT
GAGTTAGGACTATCGGCGTCGAACGTCAGACGCATCGAGCAGCGAGCTCTCGGACGGCTGAGGCGTCATCTGCAGCAGGT
CGTGGCTGCATGA

Upstream 100 bases:

>100_bases
CTGCCTCAGCCTAACGTGGCATCTGTGGACAACTTTTTCTGTGTCCACAGATTGTCTATGAGAGGTTCCATCATGGTCCA
ATACGCGTCATTGTCGGACC

Downstream 100 bases:

>100_bases
CAGGATGGAGGGCATGTGGTGGACGAAGGGACCAAGTGCTGACGAGATGGCCCGTCTGCGAGCTGTTCTCGGGTTTAACG
ACGTGAAGGTGCTCGCTCAT

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRYTDFIDGVEILDPAEEHDLFRRLDAGAIADAILAGHFLAAVPVSEAELRRISDDGVGARQTLWRQMLAIVLTQARQAA
VSYRCSVEDLIQAGCIGLGEAIERYDVRRGARFSTVAWTWIRRRIGEEVVRLSGARSRSVMREAAEVARIEEELTARWQS
VPSSDAIAARMGKDVMWVEKRRVECWEVETSFFEQVAVVQKSCDDPESGLIGLLTGQERRIVELRHGFEGEPMTITAVAH
ELGLSASNVRRIEQRALGRLRRHLQQVVAA

Sequences:

>Translated_270_residues
MRYTDFIDGVEILDPAEEHDLFRRLDAGAIADAILAGHFLAAVPVSEAELRRISDDGVGARQTLWRQMLAIVLTQARQAA
VSYRCSVEDLIQAGCIGLGEAIERYDVRRGARFSTVAWTWIRRRIGEEVVRLSGARSRSVMREAAEVARIEEELTARWQS
VPSSDAIAARMGKDVMWVEKRRVECWEVETSFFEQVAVVQKSCDDPESGLIGLLTGQERRIVELRHGFEGEPMTITAVAH
ELGLSASNVRRIEQRALGRLRRHLQQVVAA
>Mature_270_residues
MRYTDFIDGVEILDPAEEHDLFRRLDAGAIADAILAGHFLAAVPVSEAELRRISDDGVGARQTLWRQMLAIVLTQARQAA
VSYRCSVEDLIQAGCIGLGEAIERYDVRRGARFSTVAWTWIRRRIGEEVVRLSGARSRSVMREAAEVARIEEELTARWQS
VPSSDAIAARMGKDVMWVEKRRVECWEVETSFFEQVAVVQKSCDDPESGLIGLLTGQERRIVELRHGFEGEPMTITAVAH
ELGLSASNVRRIEQRALGRLRRHLQQVVAA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789098, Length=236, Percent_Identity=26.6949152542373, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: <10 (log phase) 250 (stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 30295; Mature: 30295

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYTDFIDGVEILDPAEEHDLFRRLDAGAIADAILAGHFLAAVPVSEAELRRISDDGVGA
CCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
RQTLWRQMLAIVLTQARQAAVSYRCSVEDLIQAGCIGLGEAIERYDVRRGARFSTVAWTW
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
IRRRIGEEVVRLSGARSRSVMREAAEVARIEEELTARWQSVPSSDAIAARMGKDVMWVEK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHH
RRVECWEVETSFFEQVAVVQKSCDDPESGLIGLLTGQERRIVELRHGFEGEPMTITAVAH
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEHHHHHH
ELGLSASNVRRIEQRALGRLRRHLQQVVAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRYTDFIDGVEILDPAEEHDLFRRLDAGAIADAILAGHFLAAVPVSEAELRRISDDGVGA
CCCCHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCH
RQTLWRQMLAIVLTQARQAAVSYRCSVEDLIQAGCIGLGEAIERYDVRRGARFSTVAWTW
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHH
IRRRIGEEVVRLSGARSRSVMREAAEVARIEEELTARWQSVPSSDAIAARMGKDVMWVEK
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHH
RRVECWEVETSFFEQVAVVQKSCDDPESGLIGLLTGQERRIVELRHGFEGEPMTITAVAH
HCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEHHHHHH
ELGLSASNVRRIEQRALGRLRRHLQQVVAA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3194753; 1944221; 12000953 [H]