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The map label for this gene is glmU [H]

Identifier: 50842406

GI number: 50842406

Start: 1005046

End: 1006263

Strand: Reverse

Name: glmU [H]

Synonym: PPA0922

Alternate gene names: 50842406

Gene position: 1006263-1005046 (Counterclockwise)

Preceding gene: 50842407

Following gene: 50842405

Centisome position: 39.3

GC content: 60.02

Gene sequence:

>1218_bases
ATGGACGTCAACTCCCGTGTGCTTGAACCGCGCGGCCTGGAGAAGGTGGCCAAGCTCATCGAAAGAGGGGTGCGCATCCC
GAATCCGTTGACCATCGACATTGATGAGGCAGTCGACATCGACAACATCAGTAGTGATGGAGTGGTCATCGGGCCTGGAT
GCCGAATCCGTGGCCGTCGGACTGTCATCTCAGCCGGGTGCATACTCGGGGATGAGGCCCCCATGACGATCCAGGACTGC
CAACTTGGCACCGAGGTCAAGCTTAAGGGCGGGTTCGCCCAGGATGCTGTTTTCCTTGACGGGGCAAGCATGGGCTCAGG
TGCCCACGTCCGCGGGGGCACTATCCTCGAGGAGGAGGCCAATGGGGCCCATACCGTCGGCCTCAAGCAAACCATCCTCA
TGCCCTTTGTCACCTTGGGGAGCCTCATCAACTTCTGTGATGTCCTCTTGGCCGGCGGCACCTCGAGGACAAACCATTCT
GAGGTCGGTTCTTCCTACATTCATTTCAACTTCACTCCCGACGGAGATAAGACGACAGCCTCCCTTTTCGGCGATGTGCC
GCGCGGGGTGCTGCTCGACCGTCATCCGATCTTCCTTGGTGGTCAGGGCGGTGCTGTCGGGCCAGTAACCACCGGATTCG
GCACCGTGGTCGGGGCAGGCTCAATCCTGCGTGACGACGTTCCCGAGGATGATCAGCTCGTGCTGCCCGCTCCCCCTGCG
ACACGTCAGCGTCCTGTCACCCCAAACAGCTACTCCAAGCTCAACCGCATCATCGCCCATAACGTCTCGTATCTGGGCAA
TTTGTCTGCTCTTGAGGCCTGGTACCGACAGATTCGTCGTCTCTTCATGTCCCGTGATCGCCTCTCCGGATTAGTCTGGC
AAGGTGCTCTCGACAACCTCGTCTCAGCGCGGAAAGAGCGAGTCAAGAGGCTTGAATCTCTCATCGGCAAAGTCCAGCCG
ACCGACGCCGGGCGCGCTCAATTGATCGACGACCGTGACGCCTTCCTCTCCTCCCTCGAGACGGCTGATTCCCCCGCACC
TGCCGAGATAGTGCGTCTATGCGGTGCGGCCGCCAATTCTGGGGCCAACTACCTCGACGTTATCCAGTCCTTCGACGAAG
CAGCCCGGAATCAGGTCGTCGAATGGCTGGGGAAAATCGTCACTGCCCAGCAGGACCGGGCGCAAGAGGTCGTTGACCAG
TTGCCATTGCCGTTCTGA

Upstream 100 bases:

>100_bases
GGCATTCGTCGTCACTGCGGCCTGGCTCGTCATGGCCGGCGGCCGACAACGGGAGTGACTAGGCTGGCAGCAACGGACCA
CGACCTCGAAAGGACCATCG

Downstream 100 bases:

>100_bases
CTACGGTGTTCTTCCTCCGTGCCGGAATCTCGCCACGAAACCGTCACTAGCTCCGGAAAAAATGACGGCACAAGGAGGAG
CCATGACGACAACTACCGAC

Product: putative UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MDVNSRVLEPRGLEKVAKLIERGVRIPNPLTIDIDEAVDIDNISSDGVVIGPGCRIRGRRTVISAGCILGDEAPMTIQDC
QLGTEVKLKGGFAQDAVFLDGASMGSGAHVRGGTILEEEANGAHTVGLKQTILMPFVTLGSLINFCDVLLAGGTSRTNHS
EVGSSYIHFNFTPDGDKTTASLFGDVPRGVLLDRHPIFLGGQGGAVGPVTTGFGTVVGAGSILRDDVPEDDQLVLPAPPA
TRQRPVTPNSYSKLNRIIAHNVSYLGNLSALEAWYRQIRRLFMSRDRLSGLVWQGALDNLVSARKERVKRLESLIGKVQP
TDAGRAQLIDDRDAFLSSLETADSPAPAEIVRLCGAAANSGANYLDVIQSFDEAARNQVVEWLGKIVTAQQDRAQEVVDQ
LPLPF

Sequences:

>Translated_405_residues
MDVNSRVLEPRGLEKVAKLIERGVRIPNPLTIDIDEAVDIDNISSDGVVIGPGCRIRGRRTVISAGCILGDEAPMTIQDC
QLGTEVKLKGGFAQDAVFLDGASMGSGAHVRGGTILEEEANGAHTVGLKQTILMPFVTLGSLINFCDVLLAGGTSRTNHS
EVGSSYIHFNFTPDGDKTTASLFGDVPRGVLLDRHPIFLGGQGGAVGPVTTGFGTVVGAGSILRDDVPEDDQLVLPAPPA
TRQRPVTPNSYSKLNRIIAHNVSYLGNLSALEAWYRQIRRLFMSRDRLSGLVWQGALDNLVSARKERVKRLESLIGKVQP
TDAGRAQLIDDRDAFLSSLETADSPAPAEIVRLCGAAANSGANYLDVIQSFDEAARNQVVEWLGKIVTAQQDRAQEVVDQ
LPLPF
>Mature_405_residues
MDVNSRVLEPRGLEKVAKLIERGVRIPNPLTIDIDEAVDIDNISSDGVVIGPGCRIRGRRTVISAGCILGDEAPMTIQDC
QLGTEVKLKGGFAQDAVFLDGASMGSGAHVRGGTILEEEANGAHTVGLKQTILMPFVTLGSLINFCDVLLAGGTSRTNHS
EVGSSYIHFNFTPDGDKTTASLFGDVPRGVLLDRHPIFLGGQGGAVGPVTTGFGTVVGAGSILRDDVPEDDQLVLPAPPA
TRQRPVTPNSYSKLNRIIAHNVSYLGNLSALEAWYRQIRRLFMSRDRLSGLVWQGALDNLVSARKERVKRLESLIGKVQP
TDAGRAQLIDDRDAFLSSLETADSPAPAEIVRLCGAAANSGANYLDVIQSFDEAARNQVVEWLGKIVTAQQDRAQEVVDQ
LPLPF

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 43384; Mature: 43384

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVNSRVLEPRGLEKVAKLIERGVRIPNPLTIDIDEAVDIDNISSDGVVIGPGCRIRGRR
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCE
TVISAGCILGDEAPMTIQDCQLGTEVKLKGGFAQDAVFLDGASMGSGAHVRGGTILEEEA
EEEEECCEECCCCCCCHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCEECCCEEEECCC
NGAHTVGLKQTILMPFVTLGSLINFCDVLLAGGTSRTNHSEVGSSYIHFNFTPDGDKTTA
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCCCCHHH
SLFGDVPRGVLLDRHPIFLGGQGGAVGPVTTGFGTVVGAGSILRDDVPEDDQLVLPAPPA
HHHCCCCCCEEECCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCEEECCCCC
TRQRPVTPNSYSKLNRIIAHNVSYLGNLSALEAWYRQIRRLFMSRDRLSGLVWQGALDNL
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSARKERVKRLESLIGKVQPTDAGRAQLIDDRDAFLSSLETADSPAPAEIVRLCGAAANS
HHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
GANYLDVIQSFDEAARNQVVEWLGKIVTAQQDRAQEVVDQLPLPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDVNSRVLEPRGLEKVAKLIERGVRIPNPLTIDIDEAVDIDNISSDGVVIGPGCRIRGRR
CCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCE
TVISAGCILGDEAPMTIQDCQLGTEVKLKGGFAQDAVFLDGASMGSGAHVRGGTILEEEA
EEEEECCEECCCCCCCHHHCCCCCEEEECCCCCCCEEEEECCCCCCCCEECCCEEEECCC
NGAHTVGLKQTILMPFVTLGSLINFCDVLLAGGTSRTNHSEVGSSYIHFNFTPDGDKTTA
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEECCCCCCHHH
SLFGDVPRGVLLDRHPIFLGGQGGAVGPVTTGFGTVVGAGSILRDDVPEDDQLVLPAPPA
HHHCCCCCCEEECCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHCCCCCCCCEEECCCCC
TRQRPVTPNSYSKLNRIIAHNVSYLGNLSALEAWYRQIRRLFMSRDRLSGLVWQGALDNL
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSARKERVKRLESLIGKVQPTDAGRAQLIDDRDAFLSSLETADSPAPAEIVRLCGAAANS
HHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
GANYLDVIQSFDEAARNQVVEWLGKIVTAQQDRAQEVVDQLPLPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]