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The map label for this gene is acsA [H]

Identifier: 50842394

GI number: 50842394

Start: 991632

End: 991817

Strand: Direct

Name: acsA [H]

Synonym: PPA0910

Alternate gene names: 50842394

Gene position: 991632-991817 (Clockwise)

Preceding gene: 50842393

Following gene: 50842395

Centisome position: 38.73

GC content: 62.37

Gene sequence:

>186_bases
GTGGTCGGTGACGGCACGTGTCCGATCACCGATACCTGGTGGCAGACCGAAACTGGCATGTTCCAGATCACCACTGTGCC
GTCGATGCCGCTCAAACCAGGTGCCGCTGGGCGTCCGGTTGCTGTTGTCGACGAGGAGGGCAATGAGGTCCCTGCGGGCA
AAGAGGGCTTCCTCGTCCCCAAGTGA

Upstream 100 bases:

>100_bases
TGGCGACGCCTGGGTGCGCAAACACGATCTGTCCAGTTTGCGCATACTCGGTTCGGTTGGCTAGCCCATCAACCCGGAGG
CTTGGCGCTGCTTCCACGAT

Downstream 100 bases:

>100_bases
GCGCGTGTCGGCGAGATCAGGCTGCGACAGAATATGTGTGCCGTAGGAGTTGGCAAAATTGACCTGTTTATCTGTTTGGT
GTGATCTACAGCTATTGGGC

Product: acetyl-CoA synthetase

Products: NA

Alternate protein names: Acetate--CoA ligase; Acyl-activating enzyme [H]

Number of amino acids: Translated: 61; Mature: 61

Protein sequence:

>61_residues
MVGDGTCPITDTWWQTETGMFQITTVPSMPLKPGAAGRPVAVVDEEGNEVPAGKEGFLVPK

Sequences:

>Translated_61_residues
MVGDGTCPITDTWWQTETGMFQITTVPSMPLKPGAAGRPVAVVDEEGNEVPAGKEGFLVPK
>Mature_61_residues
MVGDGTCPITDTWWQTETGMFQITTVPSMPLKPGAAGRPVAVVDEEGNEVPAGKEGFLVPK

Specific function: Enables The Cell To Use Acetate During Aerobic Growth To Generate Energy Via The Tca Cycle, And Biosynthetic Compounds Via The Glyoxylate Shunt. Acetylates Chey, The Response Regulator Involved In Flagellar Movement And Chemotaxis. [C]

COG id: COG0365

COG function: function code I; Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1790505, Length=64, Percent_Identity=50, Blast_Score=59, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011904
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.1 [H]

Molecular weight: Translated: 6445; Mature: 6445

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGDGTCPITDTWWQTETGMFQITTVPSMPLKPGAAGRPVAVVDEEGNEVPAGKEGFLVP
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEECC
K
C
>Mature Secondary Structure
MVGDGTCPITDTWWQTETGMFQITTVPSMPLKPGAAGRPVAVVDEEGNEVPAGKEGFLVP
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEECC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500908 [H]