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The map label for this gene is hmuT [H]

Identifier: 50842267

GI number: 50842267

Start: 857622

End: 858941

Strand: Direct

Name: hmuT [H]

Synonym: PPA0780

Alternate gene names: 50842267

Gene position: 857622-858941 (Clockwise)

Preceding gene: 50842266

Following gene: 50842268

Centisome position: 33.5

GC content: 59.32

Gene sequence:

>1320_bases
GTGACGAAATCGATCTCGGCATCGTCGGAGGGCTCGCCCTCACCGCCGTGGTCTCGACGGTGGTCGTCTGCCGTCGTTAC
GCTGCCCGGATCTGATCCGTTCGTCGAACGCCGTCATTTCGCACGCAGACAAAGTGCCGGCAGGGATGGGGGCACTCGTC
CCCATCCCTGCTACATTCCCGAAAACGAGTTTCGAAAGTTGAGAACCATGATCCGGATGTACCGTCGAGTTGCCGGAGTC
GGCTTGGCTCTGACCATGTTGGTGGCCGGCTGTGGTCATTCCTCCTCGATCTCCCAAGGTCCTGCCACATCCTCCACGCC
GGTACCGTCCGTCGCGACATCGTCGACGAGGGCGGCATCAGCCACTTCACAGGCAGCGCGGGATTTGCCTGACCCGCACA
CCCTTCGCGGTCTCACGGAAGTGCCAGAACTACCTGATCCGAAGCCAGTCGAGGGGTCGTCTGCCCAAAAACTTCCAGTG
ACCGTCACTGACGTCGAGGGGAACAAGGTGACGATCAAAAGCACCTCGAGAATTCTCGCTCTTGACCTCTACGGCACCTT
GTCACGCACCCTCATTGGACTTGGATTGGGCGACAAGATCGTCGGGCGCACTGTTTCCTCCACTGAAAAGCAGTTGCATG
ACCGCCCCGTGGTGACAGAAAACGGACACGTTCTTAACGTCGAGGCCGTCGCAGGTCTGAAACCGTCGGTCATCATCGCC
GACCGCAGCGTGGGTCCGAAGGAGGCCCTCGATCAGCTCCGTAAATCCGGGATTCCGGTGGTGCTCGTAGATCCCCACCG
CAGTGTCGGCTCCACTCCTCAGCTTATTCGCACTATTGCCGATGCCGTCGGAAAGCCTGATGCAGGCGAAGCCCTGGTGA
AACGTACCCAAGAGCAGATCGACCAGGCCAAAAAGCAGATAGCAGCATGGAAACCTGCCAAGCCGATGCGAGTCGCTTTC
CTCTACGTTCGCGGAAATGCTGGCGTTTTCTTCATTCTTGGTTCTGAGAACGGGGCCAGCGAGCTTATCCAGGGGGTGGG
TGCCGATGACGTCGCCTCCGACAAAGGCATAACGACCCTCGTACCTGCCAACGCCGAATCCCTGGTCTCCATCAACCCGG
ATGCGATCTTCGTCATGAGGGATGGGCTTGCTTCCACCGGGGGGATGAAGGGACTGCTGGCTAGAGCTGGCGTCGCTAAC
ACCACCGCAGGGCGCAAGCAACGGGTTATTTCCATTCCTGATGGAATCTCGCTGTCTTTCGGGCCCCAAACCGGGGAGGT
CCTGACCGCTGTGGCCAAGGCTTTGTACGGAGTCAAATGA

Upstream 100 bases:

>100_bases
AACGTCACTGTTGACGCTGTCACCGGAAAGGTCATCGGTGACGACTCCGGTAAGGGTGCGGGACGGGGACTGCCCGTTAC
CGGTGCTGAGGGCCCATCCA

Downstream 100 bases:

>100_bases
GCGCCCTGTCACAGCCGGTTGTCCAGCGTTCTGGGATTGAGCGACGGACTCGGGTTCGCGTTATCTCCACCATCTGCCTC
GTCATCATCGTATGTGGTTT

Product: hemin receptor precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTKSISASSEGSPSPPWSRRWSSAVVTLPGSDPFVERRHFARRQSAGRDGGTRPHPCYIPENEFRKLRTMIRMYRRVAGV
GLALTMLVAGCGHSSSISQGPATSSTPVPSVATSSTRAASATSQAARDLPDPHTLRGLTEVPELPDPKPVEGSSAQKLPV
TVTDVEGNKVTIKSTSRILALDLYGTLSRTLIGLGLGDKIVGRTVSSTEKQLHDRPVVTENGHVLNVEAVAGLKPSVIIA
DRSVGPKEALDQLRKSGIPVVLVDPHRSVGSTPQLIRTIADAVGKPDAGEALVKRTQEQIDQAKKQIAAWKPAKPMRVAF
LYVRGNAGVFFILGSENGASELIQGVGADDVASDKGITTLVPANAESLVSINPDAIFVMRDGLASTGGMKGLLARAGVAN
TTAGRKQRVISIPDGISLSFGPQTGEVLTAVAKALYGVK

Sequences:

>Translated_439_residues
MTKSISASSEGSPSPPWSRRWSSAVVTLPGSDPFVERRHFARRQSAGRDGGTRPHPCYIPENEFRKLRTMIRMYRRVAGV
GLALTMLVAGCGHSSSISQGPATSSTPVPSVATSSTRAASATSQAARDLPDPHTLRGLTEVPELPDPKPVEGSSAQKLPV
TVTDVEGNKVTIKSTSRILALDLYGTLSRTLIGLGLGDKIVGRTVSSTEKQLHDRPVVTENGHVLNVEAVAGLKPSVIIA
DRSVGPKEALDQLRKSGIPVVLVDPHRSVGSTPQLIRTIADAVGKPDAGEALVKRTQEQIDQAKKQIAAWKPAKPMRVAF
LYVRGNAGVFFILGSENGASELIQGVGADDVASDKGITTLVPANAESLVSINPDAIFVMRDGLASTGGMKGLLARAGVAN
TTAGRKQRVISIPDGISLSFGPQTGEVLTAVAKALYGVK
>Mature_438_residues
TKSISASSEGSPSPPWSRRWSSAVVTLPGSDPFVERRHFARRQSAGRDGGTRPHPCYIPENEFRKLRTMIRMYRRVAGVG
LALTMLVAGCGHSSSISQGPATSSTPVPSVATSSTRAASATSQAARDLPDPHTLRGLTEVPELPDPKPVEGSSAQKLPVT
VTDVEGNKVTIKSTSRILALDLYGTLSRTLIGLGLGDKIVGRTVSSTEKQLHDRPVVTENGHVLNVEAVAGLKPSVIIAD
RSVGPKEALDQLRKSGIPVVLVDPHRSVGSTPQLIRTIADAVGKPDAGEALVKRTQEQIDQAKKQIAAWKPAKPMRVAFL
YVRGNAGVFFILGSENGASELIQGVGADDVASDKGITTLVPANAESLVSINPDAIFVMRDGLASTGGMKGLLARAGVANT
TAGRKQRVISIPDGISLSFGPQTGEVLTAVAKALYGVK

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG4558

COG function: function code P; ABC-type hemin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 46131; Mature: 46000

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSISASSEGSPSPPWSRRWSSAVVTLPGSDPFVERRHFARRQSAGRDGGTRPHPCYIP
CCCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
ENEFRKLRTMIRMYRRVAGVGLALTMLVAGCGHSSSISQGPATSSTPVPSVATSSTRAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ATSQAARDLPDPHTLRGLTEVPELPDPKPVEGSSAQKLPVTVTDVEGNKVTIKSTSRILA
HHHHHHHCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCEEEE
LDLYGTLSRTLIGLGLGDKIVGRTVSSTEKQLHDRPVVTENGHVLNVEAVAGLKPSVIIA
EEHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCCCEECCCCEEEEEEECCCCCEEEEE
DRSVGPKEALDQLRKSGIPVVLVDPHRSVGSTPQLIRTIADAVGKPDAGEALVKRTQEQI
ECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DQAKKQIAAWKPAKPMRVAFLYVRGNAGVFFILGSENGASELIQGVGADDVASDKGITTL
HHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCEEE
VPANAESLVSINPDAIFVMRDGLASTGGMKGLLARAGVANTTAGRKQRVISIPDGISLSF
ECCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEE
GPQTGEVLTAVAKALYGVK
CCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKSISASSEGSPSPPWSRRWSSAVVTLPGSDPFVERRHFARRQSAGRDGGTRPHPCYIP
CCCCCCCCCCCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
ENEFRKLRTMIRMYRRVAGVGLALTMLVAGCGHSSSISQGPATSSTPVPSVATSSTRAAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
ATSQAARDLPDPHTLRGLTEVPELPDPKPVEGSSAQKLPVTVTDVEGNKVTIKSTSRILA
HHHHHHHCCCCCHHHCCHHHCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCEEEE
LDLYGTLSRTLIGLGLGDKIVGRTVSSTEKQLHDRPVVTENGHVLNVEAVAGLKPSVIIA
EEHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCCCEECCCCEEEEEEECCCCCEEEEE
DRSVGPKEALDQLRKSGIPVVLVDPHRSVGSTPQLIRTIADAVGKPDAGEALVKRTQEQI
ECCCCHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DQAKKQIAAWKPAKPMRVAFLYVRGNAGVFFILGSENGASELIQGVGADDVASDKGITTL
HHHHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCEEE
VPANAESLVSINPDAIFVMRDGLASTGGMKGLLARAGVANTTAGRKQRVISIPDGISLSF
ECCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEE
GPQTGEVLTAVAKALYGVK
CCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]