Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 50842242

GI number: 50842242

Start: 830099

End: 831169

Strand: Direct

Name: mraY

Synonym: PPA0755

Alternate gene names: 50842242

Gene position: 830099-831169 (Clockwise)

Preceding gene: 50842241

Following gene: 50842243

Centisome position: 32.42

GC content: 55.65

Gene sequence:

>1071_bases
GTGAAGAACATCCTGCTCGCCGGTGCGGTGTCAATGATCGGCACCCTCGTCGGCACGCGGTGGTTCATCCATTGGCTCGC
CGCGAAGGGCTATGGCCAGTTCATTCGCGACGACGGCCCGACAACCCATAAGACGAAAAAGGGCACCCCGACCATGGGCG
GCGCTGTCATTATTGTCTCCGTACTGCTGGCGTACCTCGTAGCACACCTGGTGACATGGACCCATCCCTCCATCTCGGCG
CTGCTGGTGTTGTGGCTGTTTTCGGGATTGGGTTTCATCGGTTTTCTTGACGACTGGACAAAGATTTCTAAGCAGCGTTC
CTTGGGTCTTAAACCCAAAGGAAAGCTCCTCGGCCAGGCTTTTGTCGCTATCACTTTCGCTATCGGGGTGATGTATTTCC
CTGATGTCCACGGTGTGACGCCAGGGTCGCCAGCTATCTCTTTCCTGCGTGATATTTCGTGGCTGTACCTACCCGTCTGG
CTGGGCATCGTCTGGGTGATCCTGCTTATTGCAGGAAGTTCCAACGCTGTCAACCTCACCGACGGTCTTGACGGCTTAGC
TACCGGTGCGTCCACGATGGTTTTCGGCGCCTATACCGTGCTGAGCATCTGGCAGTTCAATCAGTGGTGCTCTCGCCCGA
CCACCGCAGGAAACCACTGTTATGCAGTGCGTGACCCTCACGATATTGCAGTGGTTGCCATCGCTATCGCCGGAGCGTGT
TTTGGGTTTCTGTGGTGGAATGCTAAGCCCGCCCAGATCTTTCTTGGCGACACAGGATCATTGGCTCTTGGTGGCGCTGT
TGCCGGTATGGCCGTCGTCAGTCGCACTGAGCTGCTCCTGGTCATTATTGGTGCTCTCTTCGTCATCGAAACGGTCTCGG
TTATGTTGCAGGTCAGTGTGTTTAAGATCACTGGCGGAAAACGTGTCTTTAAAATGGCCCCGTTGCACCACCACTTTGAG
CTGAAGGGGTGGGCTGAGGTGACGGTAGTCATCAGGTTCTGGATTATTTGCGGCCTTGCTGTTTCGGCTGGCCTAGGAAT
CTTCTATGCAGAATGGGTGGCAGGGCAGTGA

Upstream 100 bases:

>100_bases
TAGGTTGGACCTCACACGATGTCGTTTTACTCAAAGCTTCCAGAGGTCTGGCCTTGGAGCGAGTAGGACGCGAAGTGTTC
GAGGAAAGAGAGGCCCAGGC

Downstream 100 bases:

>100_bases
CGTTCTCCGGAAAGGTTGATCTCAGCGCGGCTGACCGGCTCTTCGACTGGTCTGGTGTGCATGTTGTCATCGCTGGTTTA
GGCACGTCCGGCTATGCCGC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MKNILLAGAVSMIGTLVGTRWFIHWLAAKGYGQFIRDDGPTTHKTKKGTPTMGGAVIIVSVLLAYLVAHLVTWTHPSISA
LLVLWLFSGLGFIGFLDDWTKISKQRSLGLKPKGKLLGQAFVAITFAIGVMYFPDVHGVTPGSPAISFLRDISWLYLPVW
LGIVWVILLIAGSSNAVNLTDGLDGLATGASTMVFGAYTVLSIWQFNQWCSRPTTAGNHCYAVRDPHDIAVVAIAIAGAC
FGFLWWNAKPAQIFLGDTGSLALGGAVAGMAVVSRTELLLVIIGALFVIETVSVMLQVSVFKITGGKRVFKMAPLHHHFE
LKGWAEVTVVIRFWIICGLAVSAGLGIFYAEWVAGQ

Sequences:

>Translated_356_residues
MKNILLAGAVSMIGTLVGTRWFIHWLAAKGYGQFIRDDGPTTHKTKKGTPTMGGAVIIVSVLLAYLVAHLVTWTHPSISA
LLVLWLFSGLGFIGFLDDWTKISKQRSLGLKPKGKLLGQAFVAITFAIGVMYFPDVHGVTPGSPAISFLRDISWLYLPVW
LGIVWVILLIAGSSNAVNLTDGLDGLATGASTMVFGAYTVLSIWQFNQWCSRPTTAGNHCYAVRDPHDIAVVAIAIAGAC
FGFLWWNAKPAQIFLGDTGSLALGGAVAGMAVVSRTELLLVIIGALFVIETVSVMLQVSVFKITGGKRVFKMAPLHHHFE
LKGWAEVTVVIRFWIICGLAVSAGLGIFYAEWVAGQ
>Mature_356_residues
MKNILLAGAVSMIGTLVGTRWFIHWLAAKGYGQFIRDDGPTTHKTKKGTPTMGGAVIIVSVLLAYLVAHLVTWTHPSISA
LLVLWLFSGLGFIGFLDDWTKISKQRSLGLKPKGKLLGQAFVAITFAIGVMYFPDVHGVTPGSPAISFLRDISWLYLPVW
LGIVWVILLIAGSSNAVNLTDGLDGLATGASTMVFGAYTVLSIWQFNQWCSRPTTAGNHCYAVRDPHDIAVVAIAIAGAC
FGFLWWNAKPAQIFLGDTGSLALGGAVAGMAVVSRTELLLVIIGALFVIETVSVMLQVSVFKITGGKRVFKMAPLHHHFE
LKGWAEVTVVIRFWIICGLAVSAGLGIFYAEWVAGQ

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=336, Percent_Identity=40.4761904761905, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_PROAC (Q6A9Q5)

Other databases:

- EMBL:   AE017283
- RefSeq:   YP_055469.1
- GeneID:   2931150
- GenomeReviews:   AE017283_GR
- KEGG:   pac:PPA0755
- NMPDR:   fig|267747.1.peg.746
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- ProtClustDB:   PRK00108
- BioCyc:   PACN267747:PPA0755-MONOMER
- BRENDA:   2.7.8.13
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 38315; Mature: 38315

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xfea5310)-; HASH(0x10829438)-; HASH(0x10ce4c8c)-; HASH(0x1285527c)-; HASH(0x10ce4b90)-; HASH(0x107c515c)-; HASH(0x1212baf8)-; HASH(0x1249d4a8)-; HASH(0x10ce4cd4)-; HASH(0x107c51ec)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILLAGAVSMIGTLVGTRWFIHWLAAKGYGQFIRDDGPTTHKTKKGTPTMGGAVIIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
VLLAYLVAHLVTWTHPSISALLVLWLFSGLGFIGFLDDWTKISKQRSLGLKPKGKLLGQA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FVAITFAIGVMYFPDVHGVTPGSPAISFLRDISWLYLPVWLGIVWVILLIAGSSNAVNLT
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
DGLDGLATGASTMVFGAYTVLSIWQFNQWCSRPTTAGNHCYAVRDPHDIAVVAIAIAGAC
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
FGFLWWNAKPAQIFLGDTGSLALGGAVAGMAVVSRTELLLVIIGALFVIETVSVMLQVSV
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FKITGGKRVFKMAPLHHHFELKGWAEVTVVIRFWIICGLAVSAGLGIFYAEWVAGQ
EEEECCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCH
>Mature Secondary Structure
MKNILLAGAVSMIGTLVGTRWFIHWLAAKGYGQFIRDDGPTTHKTKKGTPTMGGAVIIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
VLLAYLVAHLVTWTHPSISALLVLWLFSGLGFIGFLDDWTKISKQRSLGLKPKGKLLGQA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FVAITFAIGVMYFPDVHGVTPGSPAISFLRDISWLYLPVWLGIVWVILLIAGSSNAVNLT
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
DGLDGLATGASTMVFGAYTVLSIWQFNQWCSRPTTAGNHCYAVRDPHDIAVVAIAIAGAC
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHH
FGFLWWNAKPAQIFLGDTGSLALGGAVAGMAVVSRTELLLVIIGALFVIETVSVMLQVSV
HHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
FKITGGKRVFKMAPLHHHFELKGWAEVTVVIRFWIICGLAVSAGLGIFYAEWVAGQ
EEEECCCEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA