Click here to switch to the map view.

The map label for this gene is pntB [H]

Identifier: 50842113

GI number: 50842113

Start: 692022

End: 693443

Strand: Direct

Name: pntB [H]

Synonym: PPA0626

Alternate gene names: 50842113

Gene position: 692022-693443 (Clockwise)

Preceding gene: 50842112

Following gene: 50842114

Centisome position: 27.03

GC content: 57.45

Gene sequence:

>1422_bases
ATGACGTCAACACTTCTTATTGCCCCGTTGGCCGGGTCGTTGGTGAATTTCGTCAACGCATCCTTCATCGTCGCAGGCCT
ACTGTTCATCTTTGCCCTGGCCGGTCTGTCTAAATTTGAGACTTCTAAGAAGGGTAATGCCTATGGCATTCTCGGCATGG
TCATCGCGATTGTCGCGACGATCGTCGCTCTGGTGAAGTTGCCGGGATACTCGCCGGTATCCATCGTTTTGCTCTTCATC
CCGATGCTTATTGGCGGCGCTTTCGGCGTGTGGAAGGCCGTTAAGGTCGAGATGACCGGAATGCCTGAGCTCATCGCTCA
GCTGCACTCCTTCGTCGGTCTGGCCGCTGTACTTATCGGGTTCAACGCGTTCGCTGAGGAGGGAACCGGTGCCAGCACCT
TCCAGCTTTCCGAGATCTGGATTGGCATCTTCATTGGCGCTCTTACCTTCACGGGATCGCTGGTGGCCTGGGGCAAGCTC
TCGGGCAAAGTCGCTTCAAAGCCACTGACCCTGCCAGGTCGTAATTGGATCAACCTTGGTCTGCTGGTCGTTATCATCGC
CTGCGGTATCTGGTTCTCCAATGTTTCTGGTGGTATTGCGTGGCTGCCGCTGGCGCTACTGACTCTGGCCTCGCTGTTCC
TCGGCTTCCACCTCGTCGCCGCTATCGGTGGCGCGGATATGCCAGTCGTCATTTCGATGCTGAACAGCTACTCCGGTTGG
GCAGCTGCCTTCTCCGGATTTAGTTTGCACATCCCGGTGCTTATCGTCACCGGTGCCCTCGTCGGCTTCTCCGGCGCCAT
CCTGTCCTACATCATGTGCAAGGCTATGAACCGCTCTTTCGTGTCGGTCATCCTCGGTGGTTTTGGCGATGCCCCGGCGG
TTGAGGGTGAGGGTCCTGCGGGGGAGATCACTGAGATCAAGGCTGACGAGTTGGCTTCCCAGCTGTCTGAAGCGTCCTCG
GTCATTATTGCTCCCGGATACGGCATGGCCGTGGCTCAGGCCCAGTACCCAGTCGCCGAATTGGCTAAGAAGCTGCGCGA
CAATGGTGTGGACGTTAAGTTCGCGATCCATCCGGTAGCCGGCCGTCTGCCCGGTCACATGAATGTGTTGCTCGCCGAAG
CCCACGTCCCCTACGACATCGTCATGGAGATGGACGAGATCAATGACGACTTCGCCGACGCTGACGTTGTCCTGATCATT
GGCGCCAACGACACCGTTAACCCTGCCGCTATGGATCCTGGTACCCCGATTTCGGGTATGCCAGTGCTCCACGTCTGGGA
AGGCCATGAGGTGGTTGTTTTCAAGCGCTCCATGAAGCCCGGATATGCCGGTGTGGAGAACCCGTTGTTCTTCGCCGATA
ACACCCGGATGCTCTTCGGTGATGCGAAGGCAAGCGTTGACGCTCTGGTAGCTGCTCTTTGA

Upstream 100 bases:

>100_bases
GATTGTCGCCGCGTTGACTGTGCTTATTGCCAGTATCAACATCTTTGGCGGCTTCACGGTCACCCAGCGCATGCTCAAGA
TGTTCAGGAAGGCCTGATCC

Downstream 100 bases:

>100_bases
CGGCGCCGCAACCTGTTTTCGATGCCCGCGACTGACTGACGGTCGTGGGCATCGTTGCATGCTGGGGGTGAGTGTCGCGA
GGCGGCACTATGATAACCGT

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MTSTLLIAPLAGSLVNFVNASFIVAGLLFIFALAGLSKFETSKKGNAYGILGMVIAIVATIVALVKLPGYSPVSIVLLFI
PMLIGGAFGVWKAVKVEMTGMPELIAQLHSFVGLAAVLIGFNAFAEEGTGASTFQLSEIWIGIFIGALTFTGSLVAWGKL
SGKVASKPLTLPGRNWINLGLLVVIIACGIWFSNVSGGIAWLPLALLTLASLFLGFHLVAAIGGADMPVVISMLNSYSGW
AAAFSGFSLHIPVLIVTGALVGFSGAILSYIMCKAMNRSFVSVILGGFGDAPAVEGEGPAGEITEIKADELASQLSEASS
VIIAPGYGMAVAQAQYPVAELAKKLRDNGVDVKFAIHPVAGRLPGHMNVLLAEAHVPYDIVMEMDEINDDFADADVVLII
GANDTVNPAAMDPGTPISGMPVLHVWEGHEVVVFKRSMKPGYAGVENPLFFADNTRMLFGDAKASVDALVAAL

Sequences:

>Translated_473_residues
MTSTLLIAPLAGSLVNFVNASFIVAGLLFIFALAGLSKFETSKKGNAYGILGMVIAIVATIVALVKLPGYSPVSIVLLFI
PMLIGGAFGVWKAVKVEMTGMPELIAQLHSFVGLAAVLIGFNAFAEEGTGASTFQLSEIWIGIFIGALTFTGSLVAWGKL
SGKVASKPLTLPGRNWINLGLLVVIIACGIWFSNVSGGIAWLPLALLTLASLFLGFHLVAAIGGADMPVVISMLNSYSGW
AAAFSGFSLHIPVLIVTGALVGFSGAILSYIMCKAMNRSFVSVILGGFGDAPAVEGEGPAGEITEIKADELASQLSEASS
VIIAPGYGMAVAQAQYPVAELAKKLRDNGVDVKFAIHPVAGRLPGHMNVLLAEAHVPYDIVMEMDEINDDFADADVVLII
GANDTVNPAAMDPGTPISGMPVLHVWEGHEVVVFKRSMKPGYAGVENPLFFADNTRMLFGDAKASVDALVAAL
>Mature_472_residues
TSTLLIAPLAGSLVNFVNASFIVAGLLFIFALAGLSKFETSKKGNAYGILGMVIAIVATIVALVKLPGYSPVSIVLLFIP
MLIGGAFGVWKAVKVEMTGMPELIAQLHSFVGLAAVLIGFNAFAEEGTGASTFQLSEIWIGIFIGALTFTGSLVAWGKLS
GKVASKPLTLPGRNWINLGLLVVIIACGIWFSNVSGGIAWLPLALLTLASLFLGFHLVAAIGGADMPVVISMLNSYSGWA
AAFSGFSLHIPVLIVTGALVGFSGAILSYIMCKAMNRSFVSVILGGFGDAPAVEGEGPAGEITEIKADELASQLSEASSV
IIAPGYGMAVAQAQYPVAELAKKLRDNGVDVKFAIHPVAGRLPGHMNVLLAEAHVPYDIVMEMDEINDDFADADVVLIIG
ANDTVNPAAMDPGTPISGMPVLHVWEGHEVVVFKRSMKPGYAGVENPLFFADNTRMLFGDAKASVDALVAAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=474, Percent_Identity=48.5232067510549, Blast_Score=401, Evalue=1e-112,
Organism=Homo sapiens, GI122939153, Length=474, Percent_Identity=48.5232067510549, Blast_Score=401, Evalue=1e-112,
Organism=Escherichia coli, GI1787886, Length=464, Percent_Identity=63.7931034482759, Blast_Score=557, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI17550456, Length=460, Percent_Identity=47.3913043478261, Blast_Score=373, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49322; Mature: 49190

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTLLIAPLAGSLVNFVNASFIVAGLLFIFALAGLSKFETSKKGNAYGILGMVIAIVAT
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHH
IVALVKLPGYSPVSIVLLFIPMLIGGAFGVWKAVKVEMTGMPELIAQLHSFVGLAAVLIG
HHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHH
FNAFAEEGTGASTFQLSEIWIGIFIGALTFTGSLVAWGKLSGKVASKPLTLPGRNWINLG
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHH
LLVVIIACGIWFSNVSGGIAWLPLALLTLASLFLGFHLVAAIGGADMPVVISMLNSYSGW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
AAAFSGFSLHIPVLIVTGALVGFSGAILSYIMCKAMNRSFVSVILGGFGDAPAVEGEGPA
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCC
GEITEIKADELASQLSEASSVIIAPGYGMAVAQAQYPVAELAKKLRDNGVDVKFAIHPVA
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEECCC
GRLPGHMNVLLAEAHVPYDIVMEMDEINDDFADADVVLIIGANDTVNPAAMDPGTPISGM
CCCCCCCEEEEEECCCCHHHEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
PVLHVWEGHEVVVFKRSMKPGYAGVENPLFFADNTRMLFGDAKASVDALVAAL
CEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCC
>Mature Secondary Structure 
TSTLLIAPLAGSLVNFVNASFIVAGLLFIFALAGLSKFETSKKGNAYGILGMVIAIVAT
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHH
IVALVKLPGYSPVSIVLLFIPMLIGGAFGVWKAVKVEMTGMPELIAQLHSFVGLAAVLIG
HHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHH
FNAFAEEGTGASTFQLSEIWIGIFIGALTFTGSLVAWGKLSGKVASKPLTLPGRNWINLG
HHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHH
LLVVIIACGIWFSNVSGGIAWLPLALLTLASLFLGFHLVAAIGGADMPVVISMLNSYSGW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCH
AAAFSGFSLHIPVLIVTGALVGFSGAILSYIMCKAMNRSFVSVILGGFGDAPAVEGEGPA
HHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCC
GEITEIKADELASQLSEASSVIIAPGYGMAVAQAQYPVAELAKKLRDNGVDVKFAIHPVA
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHCCCCHHHHHHHHHCCCCEEEEEEECCC
GRLPGHMNVLLAEAHVPYDIVMEMDEINDDFADADVVLIIGANDTVNPAAMDPGTPISGM
CCCCCCCEEEEEECCCCHHHEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCC
PVLHVWEGHEVVVFKRSMKPGYAGVENPLFFADNTRMLFGDAKASVDALVAAL
CEEEEECCCEEEEEEECCCCCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]