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The map label for this gene is gpt [H]

Identifier: 50842110

GI number: 50842110

Start: 689014

End: 689517

Strand: Reverse

Name: gpt [H]

Synonym: PPA0623

Alternate gene names: 50842110

Gene position: 689517-689014 (Counterclockwise)

Preceding gene: 50842111

Following gene: 50842108

Centisome position: 26.93

GC content: 59.92

Gene sequence:

>504_bases
ATGACCGCGTACCATGCTGACGCCAGTGACCTCGAAGGCAAAGAGATCCTCACCTGGGAGACCTTCGGTGACGCCGCCGA
AGAATTAGCTGCCCAGATTCATCATTCGGGGTTCGATCCCGAGATCCTCATCGCCGTGGCACGCGGCGGCATGATCCCTG
GCGGAGCCCTCACGTATTCCCTCGGGGTCAAACTCACCGACGCCATCAATGTCGAGTTCTACACCGACGTCCAGGAAACC
CTCCCCGATCCCGTTCTGTTGGCCCCGATGCTTGACACCGAATCCATCAGGAACAAGCGAATTCTGATCGTCGACGACGT
TGTTGATTCCGGTCGCACCCTGGCCCTGGTACTCGAGTTGCTGCGCGGCTTCGAAGCCGACGTCCGCTCGGCGGTGCTCT
ATGCCAAGCCCACGACCGTCATCAACCCGGACTTCGTGTGGAAAGCCACGGACAAGTGGATCGTGTTTCCCTGGAGCGCG
AAACCTCCGGTCGGTCAACGTTGA

Upstream 100 bases:

>100_bases
CTCTTGATTGATCGTTGTCGGTCACGTCGCCACCGACCAGGCCCGCCACCGGTCCCACACCGCAAGGCGATGTCGGCTGC
GGCATCGCTAAGGTTGCTCT

Downstream 100 bases:

>100_bases
GCGCGAAACCTCCCGTTGCTCAACGCTGACTTCGACAGCACGGATCCGACTGCGACGACCACCTCGTGGAAGGACACTGC
TCCCGGATCAGGCGTTCCCA

Product: putative purine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MTAYHADASDLEGKEILTWETFGDAAEELAAQIHHSGFDPEILIAVARGGMIPGGALTYSLGVKLTDAINVEFYTDVQET
LPDPVLLAPMLDTESIRNKRILIVDDVVDSGRTLALVLELLRGFEADVRSAVLYAKPTTVINPDFVWKATDKWIVFPWSA
KPPVGQR

Sequences:

>Translated_167_residues
MTAYHADASDLEGKEILTWETFGDAAEELAAQIHHSGFDPEILIAVARGGMIPGGALTYSLGVKLTDAINVEFYTDVQET
LPDPVLLAPMLDTESIRNKRILIVDDVVDSGRTLALVLELLRGFEADVRSAVLYAKPTTVINPDFVWKATDKWIVFPWSA
KPPVGQR
>Mature_166_residues
TAYHADASDLEGKEILTWETFGDAAEELAAQIHHSGFDPEILIAVARGGMIPGGALTYSLGVKLTDAINVEFYTDVQETL
PDPVLLAPMLDTESIRNKRILIVDDVVDSGRTLALVLELLRGFEADVRSAVLYAKPTTVINPDFVWKATDKWIVFPWSAK
PPVGQR

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine [H]

COG id: COG2236

COG function: function code R; Predicted phosphoribosyltransferases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.22 [H]

Molecular weight: Translated: 18322; Mature: 18191

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYHADASDLEGKEILTWETFGDAAEELAAQIHHSGFDPEILIAVARGGMIPGGALTYS
CCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEE
LGVKLTDAINVEFYTDVQETLPDPVLLAPMLDTESIRNKRILIVDDVVDSGRTLALVLEL
ECEEEEEEEEEEEEECHHHHCCCCEEEEECCCCHHHCCCEEEEEECCCCCCCHHHHHHHH
LRGFEADVRSAVLYAKPTTVINPDFVWKATDKWIVFPWSAKPPVGQR
HHCCCCCHHHEEEEECCCEEECCCEEEEECCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TAYHADASDLEGKEILTWETFGDAAEELAAQIHHSGFDPEILIAVARGGMIPGGALTYS
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEEE
LGVKLTDAINVEFYTDVQETLPDPVLLAPMLDTESIRNKRILIVDDVVDSGRTLALVLEL
ECEEEEEEEEEEEEECHHHHCCCCEEEEECCCCHHHCCCEEEEEECCCCCCCHHHHHHHH
LRGFEADVRSAVLYAKPTTVINPDFVWKATDKWIVFPWSAKPPVGQR
HHCCCCCHHHEEEEECCCEEECCCEEEEECCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA