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The map label for this gene is arcD [H]

Identifier: 50842068

GI number: 50842068

Start: 643038

End: 644519

Strand: Direct

Name: arcD [H]

Synonym: PPA0582

Alternate gene names: 50842068

Gene position: 643038-644519 (Clockwise)

Preceding gene: 50842067

Following gene: 50842069

Centisome position: 25.12

GC content: 56.34

Gene sequence:

>1482_bases
ATGGCTGAGCAAGTCGTTGGACAGGCGTCTACAGAAGTATCCATGGGTGAAGACGTCAATGTTGGGAAGCTGTCATTCCC
CGCAATGCTTTCTCTTGTCGTCGGTTCCATGATCGGCGGCGGTATTTTTTCGCTTCCGCAGAATATTGCTGCTGCCGCTA
GTCCAGGTCCTATGGTGATTGGTTGGACGATCACCGGGATCGGAATGATCTGTTTGGCGATGGTCTATCAGAAGTTGGCT
ATCCGTCGTCCTGATCTGGATAACGGCATCTATGCCTATGCCAAGGCGGGATTTGGTGATTTCATCGGGTTCAACTCGGC
GTGGGGCTATTGGCTCTCTGCCCTCATTGGCAACGTCGGGTATTTGGTGCTGCTTTTCTCGACCGTTGGCAAGTTTGTTC
CTGCTTTCGCGGGTGGTAACACCGTGTGGGCGGTGCTTGCGGCGTCAGTTCTGCTGTGGTTGACCCACGCTCTCGTTCTG
GCTGGGGTTCGTACTGCTGCTTTTGTCAACACGATCGCGACAATTGCCAAGATTGTGCCGTTGATAACATTCATTGCCAT
TTGTGCTGTTGCGTTCGATGTTGGTGTGTTTACCGAGGACTTCTGGGGGAGCCACGCGGGCTTGGGCAGTGTCTTTGCCC
AGACCAAGAGCATGATGCTCGTCACCGTGTGGGTGTTTATTGGGATCGAGGGTGCGTCGATCTACTCGAAGCGTGCTCGC
AAACGTTCTGATGTGGGCAAGGCGACTGTTGGTGGTTTTCTCTTCGTCCTGGTTCTCCTCATCGGTGTCAACCTCCTGAG
CATGGGGATCATGCATCGGGCCAAGCTGGCCGGCTTGCCCGACGCGTCTATGGGTGATGTTCTGTCCTCTGTCGTCGGGC
CGTGGGGCTCGGTGCTTGTCAGTGCTGGTGTCATCATTTCCCTGCTTGGGGCTCTACTGGCCTGGATCCTACTGTGCGGT
GAGACGATGCAGGTGCCGGGTGAGGACGGCACCATGCCGAAACTGTTCGGACGGATCAACAAACATGAGGCTCCAGCTCC
CGCTTTGTGGATCACCAACATCGTCTCCCAGATATGCCTTGTCATGACGGTGTTGTGGGACGGTGCTTACTTGGCGATGG
CGACCCTGGCTGCCGCCCTCATCCTGGTGCCGTACCTGCTGTCAGCCGCATTCGCCCTGAAGATGGTGATCAAGGGCGAA
ACCTATGAGAACGGTCCCCGATCACAGCGAGTGCGTGATGCCGTGGTCGCAACTGTCGCAACCTTGTACGGCATCTGGCT
CGTCGTTGCCGCAGGCGCGGATGCTCTCATGCTTGCGGCCCTGCTCTACTTGCCTGGTGCTGCAGTGTTCGTCTGGGCCA
AGCGTGAGCAGCGGGCCAAACGGATTTTCAAACCCTACGAGATCGGCGTTCTTGTCCTGCTGGCGTTGATTTCCGTGGTA
TCCATCATTTCCATAGTTACCGGGAGGCTTTCCTTGACGTGA

Upstream 100 bases:

>100_bases
TTGACGTCCGCTGTAGATCCTCCCTATGGTCATTCTGGGGCCAGGCGCTTCGCCAGCTGGCCATCGCAACAATGGTGTGG
CGAAGGGTTATGAGGTGAGT

Downstream 100 bases:

>100_bases
TTGCTCTACCCACCCTTAATGTGGAAACTCATAAATATATACACAATCAGTGATGTAAGAGGGCAATCCTACGGTGCTGC
GGTGATTGCCATGGCAGGGA

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MAEQVVGQASTEVSMGEDVNVGKLSFPAMLSLVVGSMIGGGIFSLPQNIAAAASPGPMVIGWTITGIGMICLAMVYQKLA
IRRPDLDNGIYAYAKAGFGDFIGFNSAWGYWLSALIGNVGYLVLLFSTVGKFVPAFAGGNTVWAVLAASVLLWLTHALVL
AGVRTAAFVNTIATIAKIVPLITFIAICAVAFDVGVFTEDFWGSHAGLGSVFAQTKSMMLVTVWVFIGIEGASIYSKRAR
KRSDVGKATVGGFLFVLVLLIGVNLLSMGIMHRAKLAGLPDASMGDVLSSVVGPWGSVLVSAGVIISLLGALLAWILLCG
ETMQVPGEDGTMPKLFGRINKHEAPAPALWITNIVSQICLVMTVLWDGAYLAMATLAAALILVPYLLSAAFALKMVIKGE
TYENGPRSQRVRDAVVATVATLYGIWLVVAAGADALMLAALLYLPGAAVFVWAKREQRAKRIFKPYEIGVLVLLALISVV
SIISIVTGRLSLT

Sequences:

>Translated_493_residues
MAEQVVGQASTEVSMGEDVNVGKLSFPAMLSLVVGSMIGGGIFSLPQNIAAAASPGPMVIGWTITGIGMICLAMVYQKLA
IRRPDLDNGIYAYAKAGFGDFIGFNSAWGYWLSALIGNVGYLVLLFSTVGKFVPAFAGGNTVWAVLAASVLLWLTHALVL
AGVRTAAFVNTIATIAKIVPLITFIAICAVAFDVGVFTEDFWGSHAGLGSVFAQTKSMMLVTVWVFIGIEGASIYSKRAR
KRSDVGKATVGGFLFVLVLLIGVNLLSMGIMHRAKLAGLPDASMGDVLSSVVGPWGSVLVSAGVIISLLGALLAWILLCG
ETMQVPGEDGTMPKLFGRINKHEAPAPALWITNIVSQICLVMTVLWDGAYLAMATLAAALILVPYLLSAAFALKMVIKGE
TYENGPRSQRVRDAVVATVATLYGIWLVVAAGADALMLAALLYLPGAAVFVWAKREQRAKRIFKPYEIGVLVLLALISVV
SIISIVTGRLSLT
>Mature_492_residues
AEQVVGQASTEVSMGEDVNVGKLSFPAMLSLVVGSMIGGGIFSLPQNIAAAASPGPMVIGWTITGIGMICLAMVYQKLAI
RRPDLDNGIYAYAKAGFGDFIGFNSAWGYWLSALIGNVGYLVLLFSTVGKFVPAFAGGNTVWAVLAASVLLWLTHALVLA
GVRTAAFVNTIATIAKIVPLITFIAICAVAFDVGVFTEDFWGSHAGLGSVFAQTKSMMLVTVWVFIGIEGASIYSKRARK
RSDVGKATVGGFLFVLVLLIGVNLLSMGIMHRAKLAGLPDASMGDVLSSVVGPWGSVLVSAGVIISLLGALLAWILLCGE
TMQVPGEDGTMPKLFGRINKHEAPAPALWITNIVSQICLVMTVLWDGAYLAMATLAAALILVPYLLSAAFALKMVIKGET
YENGPRSQRVRDAVVATVATLYGIWLVVAAGADALMLAALLYLPGAAVFVWAKREQRAKRIFKPYEIGVLVLLALISVVS
IISIVTGRLSLT

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=462, Percent_Identity=41.7748917748918, Blast_Score=353, Evalue=1e-98,
Organism=Escherichia coli, GI2367353, Length=426, Percent_Identity=29.3427230046948, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1786908, Length=432, Percent_Identity=24.537037037037, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790575, Length=381, Percent_Identity=24.9343832020997, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51947; Mature: 51815

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCC
>Mature Secondary Structure 
AEQVVGQASTEVSMGEDVNVGKLSFPAMLSLVVGSMIGGGIFSLPQNIAAAASPGPMVI
CCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCHHHHHCCCCCCEEE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HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]