Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 50841736

GI number: 50841736

Start: 297213

End: 298412

Strand: Direct

Name: dnaX [H]

Synonym: PPA0244

Alternate gene names: 50841736

Gene position: 297213-298412 (Clockwise)

Preceding gene: 50841735

Following gene: 50841737

Centisome position: 11.61

GC content: 61.75

Gene sequence:

>1200_bases
GTGTTGACCGGCGTGTGGGCCGATCTTGTGGGTCAGGAGAAGGCTGTCGGGGTACTGCGTCGTGCCGCCGAATCGCAGCC
GGGGCGCTCGTCCCATGCGATGAGTCACGCATGGCTCATTACGGGTCCGCCTGGATCAGGTCGGTCGAATGCTGCGAAGG
CCTTTGCAGCGGCGCTACAGTGCGTCGACCATGGATGCGGGCAGTGCAATGCCTGTCGAACCACCTTGTCAGGCGCCCAT
CCTGACGTCACCCTAGTGCGTACTGAGGCACTGTCTATCGGCGTTGATGAAGTGCGTGAACTGGTTCGTCGAGCGGCGAT
GAATCCGGTCCACGGGTGTCACCAAGTTGTCGTCGTCGAAGATGCCGATCGCATCACTGAACGCGGAGCTGACGCCTTGC
TTAAAGCTATCGAGGAGCCTGCGCCGAAAACCGTCTGGTTGCTGTGTGCCCCTACTCCAGAGGACGTCATCGTCACAATC
AGGTCGAGATGTCGGCGCCTTCACCTAGCTACGCCGCGCGATGAGGCTGTGGCAGATCTGCTCACCCGACGTGACGGCAT
TGCCCCGGAGGTGGCTGCTGAGGCTGCCCGCGCTGGCCAAGGGCATATCGGGCGGGCGCGGCGTCTGGCCTGGGACGAGG
AGGCTCGTGCGCGACGCAACGCCATTGGTGAGCTCCCTACCCGGTTGCGGAGCTTGGGGGACTGTCTGCAAGCAGCCGAG
GACCTCGTTAATCAGGCCAGCGAGGAGGCCGCAGCCGCTACCGCAGAGGTTAATGCGGCCGAGCGGGCCGAGCTGAAGAA
AGCCCTGGGATTTGGCTCCTCTGGTGCTCGACCGCGCAATGCTCAAGCTGCTTTACGGGACCTTGAAAAGCAGCAATCCG
CTCGGTTGAAGCGGTTACAGCGCGACGCCTTGGATCGTGTGTTAACAGAGTTGACTGCTTACCACCGTGATGTATTGGCT
ATCCAAACTGGCGCTGTGCGTCCTGAGGAGGAGAACGCTTTACGAGGAGCCCGCCTTGTTAATGCTGGCTGGTCGGCCTC
CCTTCATCGGATCGCAGATTCGCAGAGTCCTGAGCACACTGTTGCCACGATCGATGCGATCCTTGCGGCGCGCAAGAGCC
TGGAACATGGCGTCACCCCCCTGCTTGTGATGGAAACTCTCCTTATCGCCATGACGGGAGTAGACCGCGCCCGCTGGTGA

Upstream 100 bases:

>100_bases
AGTGAGGCCATCCGTCAGCGCGTGACTGGATTGCTCAACCGGTGAGGAATCGAGCGGTTACGATGTCGGGCCGATCTGCA
ACGATGATCTTGTGAGCGAT

Downstream 100 bases:

>100_bases
ATCCCCCTGTCATGGCATGATGAAGTGAATAACAACGGTGTGTTGCGCCGCTGTGGCAGCGAGTTTCGTGGCACAGTGTG
AGTGTGCCGTGCCGTATCCT

Product: DNA polymerase III subunit delta'

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLTGVWADLVGQEKAVGVLRRAAESQPGRSSHAMSHAWLITGPPGSGRSNAAKAFAAALQCVDHGCGQCNACRTTLSGAH
PDVTLVRTEALSIGVDEVRELVRRAAMNPVHGCHQVVVVEDADRITERGADALLKAIEEPAPKTVWLLCAPTPEDVIVTI
RSRCRRLHLATPRDEAVADLLTRRDGIAPEVAAEAARAGQGHIGRARRLAWDEEARARRNAIGELPTRLRSLGDCLQAAE
DLVNQASEEAAAATAEVNAAERAELKKALGFGSSGARPRNAQAALRDLEKQQSARLKRLQRDALDRVLTELTAYHRDVLA
IQTGAVRPEEENALRGARLVNAGWSASLHRIADSQSPEHTVATIDAILAARKSLEHGVTPLLVMETLLIAMTGVDRARW

Sequences:

>Translated_399_residues
MLTGVWADLVGQEKAVGVLRRAAESQPGRSSHAMSHAWLITGPPGSGRSNAAKAFAAALQCVDHGCGQCNACRTTLSGAH
PDVTLVRTEALSIGVDEVRELVRRAAMNPVHGCHQVVVVEDADRITERGADALLKAIEEPAPKTVWLLCAPTPEDVIVTI
RSRCRRLHLATPRDEAVADLLTRRDGIAPEVAAEAARAGQGHIGRARRLAWDEEARARRNAIGELPTRLRSLGDCLQAAE
DLVNQASEEAAAATAEVNAAERAELKKALGFGSSGARPRNAQAALRDLEKQQSARLKRLQRDALDRVLTELTAYHRDVLA
IQTGAVRPEEENALRGARLVNAGWSASLHRIADSQSPEHTVATIDAILAARKSLEHGVTPLLVMETLLIAMTGVDRARW
>Mature_399_residues
MLTGVWADLVGQEKAVGVLRRAAESQPGRSSHAMSHAWLITGPPGSGRSNAAKAFAAALQCVDHGCGQCNACRTTLSGAH
PDVTLVRTEALSIGVDEVRELVRRAAMNPVHGCHQVVVVEDADRITERGADALLKAIEEPAPKTVWLLCAPTPEDVIVTI
RSRCRRLHLATPRDEAVADLLTRRDGIAPEVAAEAARAGQGHIGRARRLAWDEEARARRNAIGELPTRLRSLGDCLQAAE
DLVNQASEEAAAATAEVNAAERAELKKALGFGSSGARPRNAQAALRDLEKQQSARLKRLQRDALDRVLTELTAYHRDVLA
IQTGAVRPEEENALRGARLVNAGWSASLHRIADSQSPEHTVATIDAILAARKSLEHGVTPLLVMETLLIAMTGVDRARW

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=169, Percent_Identity=31.3609467455621, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787341, Length=205, Percent_Identity=32.6829268292683, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 42889; Mature: 42889

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTGVWADLVGQEKAVGVLRRAAESQPGRSSHAMSHAWLITGPPGSGRSNAAKAFAAALQ
CCCCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
CVDHGCGQCNACRTTLSGAHPDVTLVRTEALSIGVDEVRELVRRAAMNPVHGCHQVVVVE
HHHCCCCCCHHHHHHHCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEC
DADRITERGADALLKAIEEPAPKTVWLLCAPTPEDVIVTIRSRCRRLHLATPRDEAVADL
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LTRRDGIAPEVAAEAARAGQGHIGRARRLAWDEEARARRNAIGELPTRLRSLGDCLQAAE
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVNQASEEAAAATAEVNAAERAELKKALGFGSSGARPRNAQAALRDLEKQQSARLKRLQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RDALDRVLTELTAYHRDVLAIQTGAVRPEEENALRGARLVNAGWSASLHRIADSQSPEHT
HHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHH
VATIDAILAARKSLEHGVTPLLVMETLLIAMTGVDRARW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLTGVWADLVGQEKAVGVLRRAAESQPGRSSHAMSHAWLITGPPGSGRSNAAKAFAAALQ
CCCCHHHHHHCCHHHHHHHHHHHHCCCCCCHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
CVDHGCGQCNACRTTLSGAHPDVTLVRTEALSIGVDEVRELVRRAAMNPVHGCHQVVVVE
HHHCCCCCCHHHHHHHCCCCCCEEEEEHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEC
DADRITERGADALLKAIEEPAPKTVWLLCAPTPEDVIVTIRSRCRRLHLATPRDEAVADL
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LTRRDGIAPEVAAEAARAGQGHIGRARRLAWDEEARARRNAIGELPTRLRSLGDCLQAAE
HHHCCCCCHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLVNQASEEAAAATAEVNAAERAELKKALGFGSSGARPRNAQAALRDLEKQQSARLKRLQ
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
RDALDRVLTELTAYHRDVLAIQTGAVRPEEENALRGARLVNAGWSASLHRIADSQSPEHT
HHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHH
VATIDAILAARKSLEHGVTPLLVMETLLIAMTGVDRARW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]