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The map label for this gene is lutA [H]

Identifier: 50841655

GI number: 50841655

Start: 201645

End: 202439

Strand: Direct

Name: lutA [H]

Synonym: PPA0167

Alternate gene names: 50841655

Gene position: 201645-202439 (Clockwise)

Preceding gene: 50841654

Following gene: 50841656

Centisome position: 7.88

GC content: 60.38

Gene sequence:

>795_bases
ATGACAACCACTACAAGCCCTGGCGCCAGGGCTACCTTGCCCGGCTTGCCGGGGGCGGGTATGACCGTCGGGCTGTTCAT
TACGTGCATCAATGACGTGATGTTCCCTCAAACGGGCGTGGCCGTCACCACCCTGTTGGAGCGCCTCGGCTGCAAAGTTG
AGTTCCCACGGGAACAGACCTGTTGCGCCCAGATGACGACCAACACCGGATACTTCGACGAGGGTATTCCGACCGTCCGT
CAGTATGTGCGAGCCTTCGGAGACTACGACTATATCGTCGCACCCTCGGGGTCCTGTGTCGCCGCCGTCCGTGATCAGCA
CCCGATGCTTGCCGAGTATGCCGGAGATTCTGGTCTGGCCAAGGAGGTCGAGCACACCAGTCAATGCACCTACGATCTAC
CCGAGTTCCTCGTCGACATTCTCGGGGTCACTGACGTCGGCGCATATTTCCCGCATCGGGTGACGTATCACCCGTCCTGC
CACGGCAAGCGGCTGCTGAACCTTGGTGATCGTCCCTACGAGCTGCTGCGTCACGTCAAAGGCATGACCCTGGTCGACCT
TCCGATGGCCGAGCAGTGCTGCGGGTTCGGTGGCACCTTCTGCATCAAAAACCCCGATATGAGCGCGGCCATGGCTAACG
ACAAGGCTCGCCACGTCCGCGAGACTGAGGCTGAGTACGTCGTCGCCGGCGATAACTCCTGCCTCATGAATATCGGTGGT
GTGCTGTCGCGCCAGAACTCGGGCGTTAAGCCGATTCACATCGCCGAAATCCTCGCCAACACTGAGGAGGACTGA

Upstream 100 bases:

>100_bases
CGTCGGCCTCATGTCGACCCCGGTGCTCGGATGGATGGTCCCCTGAATCTGCTGACGGTTGACACCGCCTGGCATCCGTT
CATTATCAATGGAGGTCACC

Downstream 100 bases:

>100_bases
CCCATGAGTACCGAACTGCGTCGCGTCACGTACGGAAACCACGGCGTCGCCCGGTTGACCCCAGCCCCCGACAAGCCCGG
CACGTACATGGGCATGCCGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTTTTSPGARATLPGLPGAGMTVGLFITCINDVMFPQTGVAVTTLLERLGCKVEFPREQTCCAQMTTNTGYFDEGIPTVR
QYVRAFGDYDYIVAPSGSCVAAVRDQHPMLAEYAGDSGLAKEVEHTSQCTYDLPEFLVDILGVTDVGAYFPHRVTYHPSC
HGKRLLNLGDRPYELLRHVKGMTLVDLPMAEQCCGFGGTFCIKNPDMSAAMANDKARHVRETEAEYVVAGDNSCLMNIGG
VLSRQNSGVKPIHIAEILANTEED

Sequences:

>Translated_264_residues
MTTTTSPGARATLPGLPGAGMTVGLFITCINDVMFPQTGVAVTTLLERLGCKVEFPREQTCCAQMTTNTGYFDEGIPTVR
QYVRAFGDYDYIVAPSGSCVAAVRDQHPMLAEYAGDSGLAKEVEHTSQCTYDLPEFLVDILGVTDVGAYFPHRVTYHPSC
HGKRLLNLGDRPYELLRHVKGMTLVDLPMAEQCCGFGGTFCIKNPDMSAAMANDKARHVRETEAEYVVAGDNSCLMNIGG
VLSRQNSGVKPIHIAEILANTEED
>Mature_263_residues
TTTTSPGARATLPGLPGAGMTVGLFITCINDVMFPQTGVAVTTLLERLGCKVEFPREQTCCAQMTTNTGYFDEGIPTVRQ
YVRAFGDYDYIVAPSGSCVAAVRDQHPMLAEYAGDSGLAKEVEHTSQCTYDLPEFLVDILGVTDVGAYFPHRVTYHPSCH
GKRLLNLGDRPYELLRHVKGMTLVDLPMAEQCCGFGGTFCIKNPDMSAAMANDKARHVRETEAEYVVAGDNSCLMNIGGV
LSRQNSGVKPIHIAEILANTEED

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source [H]

COG id: COG0247

COG function: function code C; Fe-S oxidoreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lutA/ykgE family [H]

Homologues:

Organism=Escherichia coli, GI1786497, Length=239, Percent_Identity=41.4225941422594, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1788576, Length=226, Percent_Identity=27.8761061946903, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI48994913, Length=220, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004017
- InterPro:   IPR022822 [H]

Pfam domain/function: PF02754 CCG [H]

EC number: NA

Molecular weight: Translated: 28622; Mature: 28491

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
8.0 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTTSPGARATLPGLPGAGMTVGLFITCINDVMFPQTGVAVTTLLERLGCKVEFPREQT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCHH
CCAQMTTNTGYFDEGIPTVRQYVRAFGDYDYIVAPSGSCVAAVRDQHPMLAEYAGDSGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCHHHHHCCCCCHH
KEVEHTSQCTYDLPEFLVDILGVTDVGAYFPHRVTYHPSCHGKRLLNLGDRPYELLRHVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCHHHHHHHHC
GMTLVDLPMAEQCCGFGGTFCIKNPDMSAAMANDKARHVRETEAEYVVAGDNSCLMNIGG
CCEEEECCCHHHHHCCCCEEEEECCCCCHHHHCHHHHHHHHCCCCEEEECCCCEEEHHHH
VLSRQNSGVKPIHIAEILANTEED
HHHCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
TTTTSPGARATLPGLPGAGMTVGLFITCINDVMFPQTGVAVTTLLERLGCKVEFPREQT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCHH
CCAQMTTNTGYFDEGIPTVRQYVRAFGDYDYIVAPSGSCVAAVRDQHPMLAEYAGDSGLA
HHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEEECCCCCHHHHHCCCCCHH
KEVEHTSQCTYDLPEFLVDILGVTDVGAYFPHRVTYHPSCHGKRLLNLGDRPYELLRHVK
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCHHHHHHHHC
GMTLVDLPMAEQCCGFGGTFCIKNPDMSAAMANDKARHVRETEAEYVVAGDNSCLMNIGG
CCEEEECCCHHHHHCCCCEEEEECCCCCHHHHCHHHHHHHHCCCCEEEECCCCEEEHHHH
VLSRQNSGVKPIHIAEILANTEED
HHHCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]