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The map label for this gene is iolG2 [H]

Identifier: 50841625

GI number: 50841625

Start: 162739

End: 163731

Strand: Direct

Name: iolG2 [H]

Synonym: PPA0136

Alternate gene names: 50841625

Gene position: 162739-163731 (Clockwise)

Preceding gene: 50841624

Following gene: 50841626

Centisome position: 6.36

GC content: 62.94

Gene sequence:

>993_bases
ATGGCGAATCTGCGCGCCGGCATGGTCGGCATCGGTTCGATGGGCAAGAACCACGTCCGCAACCTGCGCGCCATCGACGG
CGTCGATCTGGTCGCGATCGCGGATGCCTCCGGCAAGGACCCGTTTGGAGTCGCCGGTGACCTACCCGTTCTCCCCGACG
TCGATGCGGTCATCGAGACTGGTATCGACTACTGTGTCGTCGCTGCCCCGACGAAGTTCCACGAGGAGATCGGTCTCAAG
CTGGCTGAGGCGGGGGTCCACGCTCTCATCGAGAAGCCGCTGGCCTACGACACTGCGGCTGCGACTCGTCTGGCTGAGGC
CTTTGAGAGCAAGGGTCTGGTGGGCGCGGTCGGCCATATCGAGCGATACAACCCGGCTTTGCAGTCGTTGCGTAAGCGTC
TGGAGAACGGCGACCTCGGTGACCTCTACCAGGTGGCTACCCGCCGTCAGGGGCCATTCCCGGCCCGTATCGCTGACGTC
GGCGTTGTCAAGGACCTCGCTAGCCACGACATTGACCTCACCGCGTGGGTTACCCAGCGTGAGTTCGAGTTGGTCGCCGC
TCGCACCATGTTCAAGGCTGGCCGCGATTACGAGGATATGGTCTCGGCGACTTGCCAGCTCTCGGGCGGGCTCATGAGCA
ACCACCTCGTCAACTGGCTGACCCCGACTAAGGAGCGTCGCACCTTCGTGACCGGCGAGAAGGGTATGTTCGTCGCGGAC
ACTCTGACCGCCGACCTCACCTTCTACTCCAACGCCAAGGTTGCGACGGTATGGGACGATATCGCTAACTTCCGTGGTGT
TGCCGAGGGTGACGTGACCAGATTCGCGATCCCGAAGCCCGAACCACTACGCACCGAGCATGAAAACTTCCGTGACGCGG
TGCTGGGCAAGGAATCCGACATCGTGACGATGACCCAGGGCGCCACGGTCGTCCAGGTGTGCGAGGCGATGATCACCTCC
GCCGCGACCGGCGAGTTCGTCAAGATCTCCTGA

Upstream 100 bases:

>100_bases
CCGCCGAGTGTGTCTCACTGCCGGTCCATCCCTCGCTGTCCCAGGCTGACCGTGAGCGCATCGTTGCCGCTGTCAATACC
TGCGCGAAAGCAGGTGCCTG

Downstream 100 bases:

>100_bases
CGTAACAGTAGTCGGGCCGGGCCGCTAAGGTCCGGCCCGATTCTCACATCTCTGCTCGATTTTCCCTGCGCCCCGGAGCG
GCCAGCTGCCCCACAGGTAG

Product: NAD-dependent dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase 2; MI 2-dehydrogenase 2 [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MANLRAGMVGIGSMGKNHVRNLRAIDGVDLVAIADASGKDPFGVAGDLPVLPDVDAVIETGIDYCVVAAPTKFHEEIGLK
LAEAGVHALIEKPLAYDTAAATRLAEAFESKGLVGAVGHIERYNPALQSLRKRLENGDLGDLYQVATRRQGPFPARIADV
GVVKDLASHDIDLTAWVTQREFELVAARTMFKAGRDYEDMVSATCQLSGGLMSNHLVNWLTPTKERRTFVTGEKGMFVAD
TLTADLTFYSNAKVATVWDDIANFRGVAEGDVTRFAIPKPEPLRTEHENFRDAVLGKESDIVTMTQGATVVQVCEAMITS
AATGEFVKIS

Sequences:

>Translated_330_residues
MANLRAGMVGIGSMGKNHVRNLRAIDGVDLVAIADASGKDPFGVAGDLPVLPDVDAVIETGIDYCVVAAPTKFHEEIGLK
LAEAGVHALIEKPLAYDTAAATRLAEAFESKGLVGAVGHIERYNPALQSLRKRLENGDLGDLYQVATRRQGPFPARIADV
GVVKDLASHDIDLTAWVTQREFELVAARTMFKAGRDYEDMVSATCQLSGGLMSNHLVNWLTPTKERRTFVTGEKGMFVAD
TLTADLTFYSNAKVATVWDDIANFRGVAEGDVTRFAIPKPEPLRTEHENFRDAVLGKESDIVTMTQGATVVQVCEAMITS
AATGEFVKIS
>Mature_329_residues
ANLRAGMVGIGSMGKNHVRNLRAIDGVDLVAIADASGKDPFGVAGDLPVLPDVDAVIETGIDYCVVAAPTKFHEEIGLKL
AEAGVHALIEKPLAYDTAAATRLAEAFESKGLVGAVGHIERYNPALQSLRKRLENGDLGDLYQVATRRQGPFPARIADVG
VVKDLASHDIDLTAWVTQREFELVAARTMFKAGRDYEDMVSATCQLSGGLMSNHLVNWLTPTKERRTFVTGEKGMFVADT
LTADLTFYSNAKVATVWDDIANFRGVAEGDVTRFAIPKPEPLRTEHENFRDAVLGKESDIVTMTQGATVVQVCEAMITSA
ATGEFVKIS

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=149, Percent_Identity=24.8322147651007, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 35565; Mature: 35434

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLRAGMVGIGSMGKNHVRNLRAIDGVDLVAIADASGKDPFGVAGDLPVLPDVDAVIET
CCCCCCCEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHC
GIDYCVVAAPTKFHEEIGLKLAEAGVHALIEKPLAYDTAAATRLAEAFESKGLVGAVGHI
CCCEEEEECCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHHHH
ERYNPALQSLRKRLENGDLGDLYQVATRRQGPFPARIADVGVVKDLASHDIDLTAWVTQR
HHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHH
EFELVAARTMFKAGRDYEDMVSATCQLSGGLMSNHLVNWLTPTKERRTFVTGEKGMFVAD
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
TLTADLTFYSNAKVATVWDDIANFRGVAEGDVTRFAIPKPEPLRTEHENFRDAVLGKESD
EHEEEEEEECCCEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCC
IVTMTQGATVVQVCEAMITSAATGEFVKIS
EEEEECCCHHHHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure 
ANLRAGMVGIGSMGKNHVRNLRAIDGVDLVAIADASGKDPFGVAGDLPVLPDVDAVIET
CCCCCCEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHC
GIDYCVVAAPTKFHEEIGLKLAEAGVHALIEKPLAYDTAAATRLAEAFESKGLVGAVGHI
CCCEEEEECCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEHHHHH
ERYNPALQSLRKRLENGDLGDLYQVATRRQGPFPARIADVGVVKDLASHDIDLTAWVTQR
HHCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEHHH
EFELVAARTMFKAGRDYEDMVSATCQLSGGLMSNHLVNWLTPTKERRTFVTGEKGMFVAD
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEECCCCEEEEE
TLTADLTFYSNAKVATVWDDIANFRGVAEGDVTRFAIPKPEPLRTEHENFRDAVLGKESD
EHEEEEEEECCCEEEEHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCC
IVTMTQGATVVQVCEAMITSAATGEFVKIS
EEEEECCCHHHHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA