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The map label for this gene is katA [H]

Identifier: 50841588

GI number: 50841588

Start: 112227

End: 113678

Strand: Direct

Name: katA [H]

Synonym: PPA0097

Alternate gene names: 50841588

Gene position: 112227-113678 (Clockwise)

Preceding gene: 50841586

Following gene: 50841601

Centisome position: 4.38

GC content: 59.37

Gene sequence:

>1452_bases
ATGCCTATTGATCCCAGCAAGCCGTCAACGAACACCAACGGGTCGCCAGCGCCTAGCGACGAATACTCCCTGACCGTCGG
CGCTGACGGCCCGGTAGTGCTCCACGACGCACATCTCATCGACACCCTGGCCCATTTCAACCGGGAAAACATCCCCGAAC
GCAAGCCTCACGCCAAGGGATCGGGGGCCTTCGGACATCTCGAGGTTACCGCTGACGTCTCGGAGTACACCAAGGCATCC
TTCCTGCAGAAGGGGCGCGAAACCCCCATGCTGGCCCGATTCTCCACAGTCGCCGGTGAGCTCGGCAGCCCTGACACCTG
GCGTGATGTGCGTGGATTCTCGTTGAAGTTCTACACCGACGAGGGCAACTTCGACATGGTCGGCAACAACACCCCGGTGT
TCTTCATGCGTGACCCGATGAAGTTCCCGCATTTCATCCGCTCCCAGAAACGGTTACCGAATTCCGGACTGCGCAGTCCG
AATATGATGTATGACTATTGGAGCCTGTCCCCCGAATCGGCCCATCAAGTGGCTTACCTCATGGGACCGCGCGGCATTCC
GCTCAGCTATCGCACTATGAACGGCTACTCCTCGCACACCTACTCATGGGTTAACGCCGAAGGGAAGATCACCTGGGTGA
AATACCACTTCATCAGTGACCAGGGTGTTCACAACATGACTGCTGACCGGGCCAAAGCGATCGTCGGTGATCACCCAGAC
ATCCACCGCGAGGACCTCTTCAACCACATTGCCGACGGCGACTATCCGTCCTGGACCGTCAAGGTGCAGCTCATGCCCTA
TGACGAAGCCAAGGATTACCGGTTCAACCCGTTCGACATCACCAAGGTGTGGCCGCATAAGGATTACCCGCTGCACACCA
TCGGCAAGTTCACTCTGGACCGCAACCCGGAGAACTTCTTCGCCCAGATCGAGCAAGCGGCCTTCTCCCCGTCGAACACC
GTTGAGGGCACTGGGTTGTCCCCAGACCGGATGCTGCTGGGTCGTGTCTTCGCCTACAACGATGCCGCCCGCAACCGTCT
GGGGGTCAACTATGAACAACTCCCTGTGAACCGGCCAACGACGCCGACAAACCAGTACACCTTCGACGGCCAGATGGCCT
TCGAACACTCCGGTTCGGCACCCACCTACGCCCCGAACTCCTACGGTCGCGATTTTGCCACCGGATACCGAACCGGTTCC
GAAGCTACCTGGGAGGCTGACGGCGAACTCGTTCGTTCCGCCCAGACCCGGCACGCGGAAGATGACGACTTCGGTCAGGC
CCACGCCCTGGTGCATGACGTCTTTTCCGACGCAGAGCGTGACGAGCTCGTCGATACTTTGGTGGACTTGATGACCAATT
TCGACATGGAAGAGCCGGTCATCGGCAACGCGCTGTCCTACTGGCGCAACATCGACGCCGGTATTGCCGAGGCAACCGAG
GGCAGAATCTGA

Upstream 100 bases:

>100_bases
TTTCTTGTACAGACTTTCTCCCGTGGCGTTATGAGCTTGGAGATGACCTTGTTGGGGGGCAATCTGGAAGAGAGCACTCA
ACTCATAAAGAGGAGTCGTC

Downstream 100 bases:

>100_bases
CGTGTTGATCGTTCCCAGCGCTGGGCTGTACTGCAGCTCAGTGCTGGTTTGACCACACCCGCCACAGCGCCGCAAATGGG
CCATCGCTTTGACGCAGTTG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 482

Protein sequence:

>483_residues
MPIDPSKPSTNTNGSPAPSDEYSLTVGADGPVVLHDAHLIDTLAHFNRENIPERKPHAKGSGAFGHLEVTADVSEYTKAS
FLQKGRETPMLARFSTVAGELGSPDTWRDVRGFSLKFYTDEGNFDMVGNNTPVFFMRDPMKFPHFIRSQKRLPNSGLRSP
NMMYDYWSLSPESAHQVAYLMGPRGIPLSYRTMNGYSSHTYSWVNAEGKITWVKYHFISDQGVHNMTADRAKAIVGDHPD
IHREDLFNHIADGDYPSWTVKVQLMPYDEAKDYRFNPFDITKVWPHKDYPLHTIGKFTLDRNPENFFAQIEQAAFSPSNT
VEGTGLSPDRMLLGRVFAYNDAARNRLGVNYEQLPVNRPTTPTNQYTFDGQMAFEHSGSAPTYAPNSYGRDFATGYRTGS
EATWEADGELVRSAQTRHAEDDDFGQAHALVHDVFSDAERDELVDTLVDLMTNFDMEEPVIGNALSYWRNIDAGIAEATE
GRI

Sequences:

>Translated_483_residues
MPIDPSKPSTNTNGSPAPSDEYSLTVGADGPVVLHDAHLIDTLAHFNRENIPERKPHAKGSGAFGHLEVTADVSEYTKAS
FLQKGRETPMLARFSTVAGELGSPDTWRDVRGFSLKFYTDEGNFDMVGNNTPVFFMRDPMKFPHFIRSQKRLPNSGLRSP
NMMYDYWSLSPESAHQVAYLMGPRGIPLSYRTMNGYSSHTYSWVNAEGKITWVKYHFISDQGVHNMTADRAKAIVGDHPD
IHREDLFNHIADGDYPSWTVKVQLMPYDEAKDYRFNPFDITKVWPHKDYPLHTIGKFTLDRNPENFFAQIEQAAFSPSNT
VEGTGLSPDRMLLGRVFAYNDAARNRLGVNYEQLPVNRPTTPTNQYTFDGQMAFEHSGSAPTYAPNSYGRDFATGYRTGS
EATWEADGELVRSAQTRHAEDDDFGQAHALVHDVFSDAERDELVDTLVDLMTNFDMEEPVIGNALSYWRNIDAGIAEATE
GRI
>Mature_482_residues
PIDPSKPSTNTNGSPAPSDEYSLTVGADGPVVLHDAHLIDTLAHFNRENIPERKPHAKGSGAFGHLEVTADVSEYTKASF
LQKGRETPMLARFSTVAGELGSPDTWRDVRGFSLKFYTDEGNFDMVGNNTPVFFMRDPMKFPHFIRSQKRLPNSGLRSPN
MMYDYWSLSPESAHQVAYLMGPRGIPLSYRTMNGYSSHTYSWVNAEGKITWVKYHFISDQGVHNMTADRAKAIVGDHPDI
HREDLFNHIADGDYPSWTVKVQLMPYDEAKDYRFNPFDITKVWPHKDYPLHTIGKFTLDRNPENFFAQIEQAAFSPSNTV
EGTGLSPDRMLLGRVFAYNDAARNRLGVNYEQLPVNRPTTPTNQYTFDGQMAFEHSGSAPTYAPNSYGRDFATGYRTGSE
ATWEADGELVRSAQTRHAEDDDFGQAHALVHDVFSDAERDELVDTLVDLMTNFDMEEPVIGNALSYWRNIDAGIAEATEG
RI

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=441, Percent_Identity=48.9795918367347, Blast_Score=429, Evalue=1e-120,
Organism=Escherichia coli, GI48994891, Length=384, Percent_Identity=42.4479166666667, Blast_Score=314, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI71998444, Length=463, Percent_Identity=46.0043196544276, Blast_Score=425, Evalue=1e-119,
Organism=Caenorhabditis elegans, GI25147792, Length=498, Percent_Identity=45.1807228915663, Blast_Score=422, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=45.8947368421053, Blast_Score=421, Evalue=1e-118,
Organism=Saccharomyces cerevisiae, GI6320462, Length=384, Percent_Identity=50.2604166666667, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321525, Length=471, Percent_Identity=39.9150743099788, Blast_Score=335, Evalue=9e-93,
Organism=Drosophila melanogaster, GI17981717, Length=447, Percent_Identity=44.7427293064877, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI19920968, Length=448, Percent_Identity=42.8571428571429, Blast_Score=381, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54304; Mature: 54172

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDPSKPSTNTNGSPAPSDEYSLTVGADGPVVLHDAHLIDTLAHFNRENIPERKPHAKG
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCC
SGAFGHLEVTADVSEYTKASFLQKGRETPMLARFSTVAGELGSPDTWRDVRGFSLKFYTD
CCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEC
EGNFDMVGNNTPVFFMRDPMKFPHFIRSQKRLPNSGLRSPNMMYDYWSLSPESAHQVAYL
CCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHEEEEE
MGPRGIPLSYRTMNGYSSHTYSWVNAEGKITWVKYHFISDQGVHNMTADRAKAIVGDHPD
ECCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCC
IHREDLFNHIADGDYPSWTVKVQLMPYDEAKDYRFNPFDITKVWPHKDYPLHTIGKFTLD
CCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEC
RNPENFFAQIEQAAFSPSNTVEGTGLSPDRMLLGRVFAYNDAARNRLGVNYEQLPVNRPT
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCC
TPTNQYTFDGQMAFEHSGSAPTYAPNSYGRDFATGYRTGSEATWEADGELVRSAQTRHAE
CCCCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEECCCHHHHHHHHHCCCC
DDDFGQAHALVHDVFSDAERDELVDTLVDLMTNFDMEEPVIGNALSYWRNIDAGIAEATE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHCC
GRI
CCC
>Mature Secondary Structure 
PIDPSKPSTNTNGSPAPSDEYSLTVGADGPVVLHDAHLIDTLAHFNRENIPERKPHAKG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECHHHHHHHHHCCCCCCCCCCCCCCC
SGAFGHLEVTADVSEYTKASFLQKGRETPMLARFSTVAGELGSPDTWRDVRGFSLKFYTD
CCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHCCCCEEEEEEC
EGNFDMVGNNTPVFFMRDPMKFPHFIRSQKRLPNSGLRSPNMMYDYWSLSPESAHQVAYL
CCCEEEECCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHEEEEE
MGPRGIPLSYRTMNGYSSHTYSWVNAEGKITWVKYHFISDQGVHNMTADRAKAIVGDHPD
ECCCCCCEEEEECCCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHCCCCCC
IHREDLFNHIADGDYPSWTVKVQLMPYDEAKDYRFNPFDITKVWPHKDYPLHTIGKFTLD
CCHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEC
RNPENFFAQIEQAAFSPSNTVEGTGLSPDRMLLGRVFAYNDAARNRLGVNYEQLPVNRPT
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCC
TPTNQYTFDGQMAFEHSGSAPTYAPNSYGRDFATGYRTGSEATWEADGELVRSAQTRHAE
CCCCCEEECCEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCEECCCHHHHHHHHHCCCC
DDDFGQAHALVHDVFSDAERDELVDTLVDLMTNFDMEEPVIGNALSYWRNIDAGIAEATE
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHCC
GRI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]