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The map label for this gene is rbsK [H]

Identifier: 50841512

GI number: 50841512

Start: 21288

End: 22217

Strand: Direct

Name: rbsK [H]

Synonym: PPA0018

Alternate gene names: 50841512

Gene position: 21288-22217 (Clockwise)

Preceding gene: 50841511

Following gene: 50841513

Centisome position: 0.83

GC content: 61.94

Gene sequence:

>930_bases
ATGAGCGGCGCGACAGCGAAAGTCACCGTCGTCGGATCGATCAATGCCGACATGAGGGTCGGCGTGGAGAGATTTCCGGG
CCCAGGGGAGACCCTGGCCGGAGGTGAGGCGACACTGACCCCCGGCGGTAAGGGAGCTAACCAGGCTCTTGCGGCGGCGC
GATGTGGCGTTCAGGTGGCGATGGTCGGAGCTGTGGGGAAGGACCCGACGGCTGAAACCGCCCTATCCCTACTATCGGAA
GGCGTTGGCCTTGATGGCGTGGTCCGTCGTGACGTATTGACGGGGACGGCCGTCGTCATGGTCGCGGATTCCGGAGAGAA
CTCAATTATCGTCATCGCGGCCGCTAATGGGACCGTTGATGCACAGACCGTCCGGGCTCAGGCCGAGCGCATCCAGGACG
CTGACGTGGTGGTGTGTCAAGGTGAGATTCCGCCTGACGGGATTGCCGAAGCTGCTCGCGGCGCCAAACGATTCGTGTTC
AATCTGGCACCGGTTGTTGACGTTGATCCAGAGGTCATTCGCATGGCCGACCCGCTGGTAGTTAACGAACATGAGGCGGC
CTTGGTGGCTCTTGCTTTGGGATCGACGACTTCTCGTCTTGAGGATGATCCTGACGCAGCTTTGCGCGAGCTGTTGAACC
TTGGGTGCCGCAGTGTTGTCATCACCTTGGGATCGGCAGGATGCATCGTCGGCGGGCCGGAAGGGTTCGACGCCGTGGCT
GCGGCGACCGTGAAGGCTGTCGATACCGTCGGTGCGGGAGATGCTTTCGTTGGTGCGTTGGCTGCAGAACTGGCTCGTGG
CCGTACTCTTGTCGAGGGTTGCCGTTTTGCTACCGCGGTGGCGACTTTGACGGTGACCAAGCCGGGGGCACAAGCCTCCT
ACCCCAGTGCTGACGAGGTGGAGAGCATTCGTCGAGGAGAACACGCATGA

Upstream 100 bases:

>100_bases
CGGTGGACCAGGCGGCCGACATATTGGCTGGCAAGCAGGTTTCTAAGACCACCCCAATCAAGGTTGTGCTGGTGACCAAG
GACAACGCGAAGGACTACGA

Downstream 100 bases:

>100_bases
AGAAGAGCGGACTGCTTAATCCCCAATTGTGTGCGGCGGTGGCCAGGTTGGGGCACACCCAGACCTTCGTCGTTGCTGAT
GCTGGGTTGCCGATTCCTCA

Product: sugar kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSGATAKVTVVGSINADMRVGVERFPGPGETLAGGEATLTPGGKGANQALAAARCGVQVAMVGAVGKDPTAETALSLLSE
GVGLDGVVRRDVLTGTAVVMVADSGENSIIVIAAANGTVDAQTVRAQAERIQDADVVVCQGEIPPDGIAEAARGAKRFVF
NLAPVVDVDPEVIRMADPLVVNEHEAALVALALGSTTSRLEDDPDAALRELLNLGCRSVVITLGSAGCIVGGPEGFDAVA
AATVKAVDTVGAGDAFVGALAAELARGRTLVEGCRFATAVATLTVTKPGAQASYPSADEVESIRRGEHA

Sequences:

>Translated_309_residues
MSGATAKVTVVGSINADMRVGVERFPGPGETLAGGEATLTPGGKGANQALAAARCGVQVAMVGAVGKDPTAETALSLLSE
GVGLDGVVRRDVLTGTAVVMVADSGENSIIVIAAANGTVDAQTVRAQAERIQDADVVVCQGEIPPDGIAEAARGAKRFVF
NLAPVVDVDPEVIRMADPLVVNEHEAALVALALGSTTSRLEDDPDAALRELLNLGCRSVVITLGSAGCIVGGPEGFDAVA
AATVKAVDTVGAGDAFVGALAAELARGRTLVEGCRFATAVATLTVTKPGAQASYPSADEVESIRRGEHA
>Mature_308_residues
SGATAKVTVVGSINADMRVGVERFPGPGETLAGGEATLTPGGKGANQALAAARCGVQVAMVGAVGKDPTAETALSLLSEG
VGLDGVVRRDVLTGTAVVMVADSGENSIIVIAAANGTVDAQTVRAQAERIQDADVVVCQGEIPPDGIAEAARGAKRFVFN
LAPVVDVDPEVIRMADPLVVNEHEAALVALALGSTTSRLEDDPDAALRELLNLGCRSVVITLGSAGCIVGGPEGFDAVAA
ATVKAVDTVGAGDAFVGALAAELARGRTLVEGCRFATAVATLTVTKPGAQASYPSADEVESIRRGEHA

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=301, Percent_Identity=36.8770764119601, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=36.8421052631579, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI87082343, Length=305, Percent_Identity=32.1311475409836, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081971, Length=286, Percent_Identity=26.5734265734266, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=310, Percent_Identity=36.7741935483871, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=30.6990881458967, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=38.562091503268, Blast_Score=150, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24583886, Length=315, Percent_Identity=30.1587301587302, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 30976; Mature: 30845

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS00584 PFKB_KINASES_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGATAKVTVVGSINADMRVGVERFPGPGETLAGGEATLTPGGKGANQALAAARCGVQVA
CCCCEEEEEEEEECCCCCEECHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEE
MVGAVGKDPTAETALSLLSEGVGLDGVVRRDVLTGTAVVMVADSGENSIIVIAAANGTVD
EEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCC
AQTVRAQAERIQDADVVVCQGEIPPDGIAEAARGAKRFVFNLAPVVDVDPEVIRMADPLV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCEE
VNEHEAALVALALGSTTSRLEDDPDAALRELLNLGCRSVVITLGSAGCIVGGPEGFDAVA
ECCCCCEEEEEEECCCHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHH
AATVKAVDTVGAGDAFVGALAAELARGRTLVEGCRFATAVATLTVTKPGAQASYPSADEV
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHH
ESIRRGEHA
HHHHCCCCC
>Mature Secondary Structure 
SGATAKVTVVGSINADMRVGVERFPGPGETLAGGEATLTPGGKGANQALAAARCGVQVA
CCCEEEEEEEEECCCCCEECHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCEEEE
MVGAVGKDPTAETALSLLSEGVGLDGVVRRDVLTGTAVVMVADSGENSIIVIAAANGTVD
EEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCEEEEEEEECCCCCEEEEEECCCCCC
AQTVRAQAERIQDADVVVCQGEIPPDGIAEAARGAKRFVFNLAPVVDVDPEVIRMADPLV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCEE
VNEHEAALVALALGSTTSRLEDDPDAALRELLNLGCRSVVITLGSAGCIVGGPEGFDAVA
ECCCCCEEEEEEECCCHHHCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCHHHHH
AATVKAVDTVGAGDAFVGALAAELARGRTLVEGCRFATAVATLTVTKPGAQASYPSADEV
HHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEEEEEEEEECCCCCCCCCCHHHH
ESIRRGEHA
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]