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The map label for this gene is pyrH [H]

Identifier: 50365373

GI number: 50365373

Start: 648680

End: 649396

Strand: Reverse

Name: pyrH [H]

Synonym: Mfl556

Alternate gene names: 50365373

Gene position: 649396-648680 (Counterclockwise)

Preceding gene: 50365374

Following gene: 50365372

Centisome position: 81.87

GC content: 30.96

Gene sequence:

>717_bases
ATGAAATATAAATATAGTACAGTTTTATTAAAACTGAGCGGTGAAGCTTTAAAAAGCGAAAATGAAATTTACAACAAAGA
AAAATTAGAAGACATTGCTAAACAAATTGTTGAGTTAGCAAAAAATGGATTAAAATTAGGAATCGTTATTGGTGGAGGAA
ATATCTGAAGAGGTAAACTTGGAACTGATATTGATATGCCACAAATTAATGCTGACTACATGGGAATGTTAGCAACTGTT
ATGAATGGTTTAGCACTTGAATCAACTATCAAACGATTAGGATATGACAAAGTTAATGTTTATTCTTCTTTACCAATTGA
AACAGTTACAGATGATTACAACTTTAAAAGAGCTCGTTTAAAAATGAATGAAGGCTACATTTCAATTTTTGTTGGTGGTA
CAGGGTTCTCTTACTTTACAACAGATACTAATTCAGTAATCCGTGCAATCGAAATTGGTGCTGATGCAGTATTGATGGCA
AAAAATGGAGTAAAAGGAGTTTATGACTCAGATCCAAATTTAAATCCGAATGCAAAATTTTATAAAAAATTAACTCATCG
TGAAATAGCTGAAAATCAATTACGCGTAATGGATTTAACAGCTGCAACATTGGCTAAGGATGCAAAACTTCCAATTGAAG
TATTTGACATGCAAGGACAAAACAACATAATTAAGGTTATGGAAGGTTCATTAGAATCAACAATAATAGAAGAATAG

Upstream 100 bases:

>100_bases
ATTAAAAAATAACCTAAAATAAATAGCAAGTATTCTATTATGAATACTTTTTTTATTGTCTATTTTGGGTATAATAAATA
AGATGAATGAGGTATTTAAT

Downstream 100 bases:

>100_bases
AGGAAAAAAATATGGATGAAATTTTATTAATAGCAGAACAACAAATGGAAGATACTGTTGTTGCTTGACAAGAACATATA
AAAACAATTAGAACAGGTAG

Product: uridine monophosphate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNIWRGKLGTDIDMPQINADYMGMLATV
MNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLKMNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMA
KNGVKGVYDSDPNLNPNAKFYKKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE

Sequences:

>Translated_238_residues
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNI*RGKLGTDIDMPQINADYMGMLATV
MNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLKMNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMA
KNGVKGVYDSDPNLNPNAKFYKKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE
>Mature_238_residues
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNI*RGKLGTDIDMPQINADYMGMLATV
MNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLKMNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMA
KNGVKGVYDSDPNLNPNAKFYKKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=238, Percent_Identity=42.436974789916, Blast_Score=176, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26189; Mature: 26189

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNIRGKLG
CCEEEEEEEEEECCHHHCCCHHHCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
TDIDMPQINADYMGMLATVMNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLK
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCEEEEEE
MNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMAKNGVKGVYDSDPNLNPNAKFY
ECCCEEEEEECCCCCEEEECCHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHH
KKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHCCC
>Mature Secondary Structure
MKYKYSTVLLKLSGEALKSENEIYNKEKLEDIAKQIVELAKNGLKLGIVIGGGNIRGKLG
CCEEEEEEEEEECCHHHCCCHHHCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCC
TDIDMPQINADYMGMLATVMNGLALESTIKRLGYDKVNVYSSLPIETVTDDYNFKRARLK
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCEEEEEE
MNEGYISIFVGGTGFSYFTTDTNSVIRAIEIGADAVLMAKNGVKGVYDSDPNLNPNAKFY
ECCCEEEEEECCCCCEEEECCHHHHEEEEECCCCEEEEECCCCCCCCCCCCCCCCCHHHH
KKLTHREIAENQLRVMDLTAATLAKDAKLPIEVFDMQGQNNIIKVMEGSLESTIIEE
HHHHHHHHHHCCEEEEEEHHHHHHCCCCCCEEEEECCCCCCEEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA