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The map label for this gene is frr [H]

Identifier: 50365372

GI number: 50365372

Start: 648123

End: 648668

Strand: Reverse

Name: frr [H]

Synonym: Mfl555

Alternate gene names: 50365372

Gene position: 648668-648123 (Counterclockwise)

Preceding gene: 50365373

Following gene: 50365371

Centisome position: 81.78

GC content: 28.57

Gene sequence:

>546_bases
ATGGATGAAATTTTATTAATAGCAGAACAACAAATGGAAGATACTGTTGTTGCTTGACAAGAACATATAAAAACAATTAG
AACAGGTAGAGCAAGTGCTACAATGCTAGACAAAGTTATGGTTAATTACTATGGAACTCCAACTCCCGTTAATCAAACTG
CTCAAATATCAACACCTGAACCACAATTGTTAGTAATCAAACCTTGAGACAAAACTTTAATTCAAGAAGTGGTTGCAGCA
ATTAATAAATCAGATTTAAATTTAAATCCAGTTTCTGATGCTGAGGTTGTAAGAATAAACATACCAGCTTTAACAGAAGA
AATCAGAAAAGATTTAGTTAAAAAAATGAATAAAGAATTAGAAAACTTTAAAGTACGTATTAGAAATATTCGTAGAGATT
CAATCGATACAGCTAAAAAAGATAAATCAATAAGTGAAGATGTTGTTAAAGGTATTGAAACAGATATTCAAAAATTAACA
GACTCAAGTATTAAGCAATTAGACGAAATATCAAAAGTTAAAGAAAAAGAATTAATGGCAATATAG

Upstream 100 bases:

>100_bases
TTCCAATTGAAGTATTTGACATGCAAGGACAAAACAACATAATTAAGGTTATGGAAGGTTCATTAGAATCAACAATAATA
GAAGAATAGAGGAAAAAAAT

Downstream 100 bases:

>100_bases
ATTAAAACATTTGTTATACAAATGTTTTTTCCTTAGAAGGTGGGAATAAAAATGGAAAACATAATTAGCATAGTCAAAAA
AGACTTAAAAGAAATTGCGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MDEILLIAEQQMEDTVVAWQEHIKTIRTGRASATMLDKVMVNYYGTPTPVNQTAQISTPEPQLLVIKPWDKTLIQEVVAA
INKSDLNLNPVSDAEVVRINIPALTEEIRKDLVKKMNKELENFKVRIRNIRRDSIDTAKKDKSISEDVVKGIETDIQKLT
DSSIKQLDEISKVKEKELMAI

Sequences:

>Translated_181_residues
MDEILLIAEQQMEDTVVA*QEHIKTIRTGRASATMLDKVMVNYYGTPTPVNQTAQISTPEPQLLVIKP*DKTLIQEVVAA
INKSDLNLNPVSDAEVVRINIPALTEEIRKDLVKKMNKELENFKVRIRNIRRDSIDTAKKDKSISEDVVKGIETDIQKLT
DSSIKQLDEISKVKEKELMAI
>Mature_181_residues
MDEILLIAEQQMEDTVVA*QEHIKTIRTGRASATMLDKVMVNYYGTPTPVNQTAQISTPEPQLLVIKP*DKTLIQEVVAA
INKSDLNLNPVSDAEVVRINIPALTEEIRKDLVKKMNKELENFKVRIRNIRRDSIDTAKKDKSISEDVVKGIETDIQKLT
DSSIKQLDEISKVKEKELMAI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=155, Percent_Identity=34.1935483870968, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI291042689, Length=174, Percent_Identity=32.183908045977, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786368, Length=175, Percent_Identity=45.1428571428571, Blast_Score=129, Evalue=9e-32,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20174; Mature: 20174

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEILLIAEQQMEDTVVAQEHIKTIRTGRASATMLDKVMVNYYGTPTPVNQTAQISTPEP
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
QLLVIKPDKTLIQEVVAAINKSDLNLNPVSDAEVVRINIPALTEEIRKDLVKKMNKELEN
CEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHH
FKVRIRNIRRDSIDTAKKDKSISEDVVKGIETDIQKLTDSSIKQLDEISKVKEKELMAI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDEILLIAEQQMEDTVVAQEHIKTIRTGRASATMLDKVMVNYYGTPTPVNQTAQISTPEP
CCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCCC
QLLVIKPDKTLIQEVVAAINKSDLNLNPVSDAEVVRINIPALTEEIRKDLVKKMNKELEN
CEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHH
FKVRIRNIRRDSIDTAKKDKSISEDVVKGIETDIQKLTDSSIKQLDEISKVKEKELMAI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA