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The map label for this gene is ftsK [H]

Identifier: 50364915

GI number: 50364915

Start: 124565

End: 127426

Strand: Direct

Name: ftsK [H]

Synonym: Mfl100

Alternate gene names: 50364915

Gene position: 124565-127426 (Clockwise)

Preceding gene: 50364914

Following gene: 50364916

Centisome position: 15.7

GC content: 29.18

Gene sequence:

>2862_bases
ATGGAAAAAAATAAAGATGAAAAGTTTTTAGCTAATTACGAATGAAATGAAGAAAAAACTGCCGCATTTGTGACGACTAA
GCAAAAAAGAAGAAATGACTCTATATCATGAATGGTTACAGGATTAGTTATCTTGTTTATTACTGTATTCTCATTAGGGA
GAATTACTGTTATAGGTCAATTCTTAGATGACGTTTTCTTTAATTTTATTTTTGGTTGATTCAAATACTTTATTTACATA
GTACTATTTATAGTAGATCTATGTATATTTTCGGGTATAAGATTTAAATTCAAAAAGAGATTTTTATTCATGGTTATATC
ATCTTTTATCTTATTGTGTTGATTAATATCTCTAATACTTTTTACACAAATAATAGCTTCAAAAAATGAAAATTTAAATA
AATTGTGACAAGCCAATTTCTTTGCACAAATGTTCAACGTATATGCAAAAGAATGAGTTGATCATTCAATATTTTCAGGA
CAATACTATAAAGAAGTGATTGATTACTTCTTAAAAACAGGTTCAGATGGATATTTCAACTTATATAGTGGTGGTGGTAT
AACTGGCACTTTAATGGTAGGCATAACATCATATTTATCAATAGTAGGTTCATATATTTTATTAGTATTCTTAATGTTCA
TTAATGGAATGTGAATCTTTACAGGAGATCCAATTTTCTTATTCAAACCAAAAGCAAAAAGAAAAGGGAAAGCTTTAAGA
ATATTAACTTTAAAATCAAAAAGAAATCCTAATTCTAAAAGACCAGTTGCTGTTCAAAACGAAATTCATGCAGAACCAAA
AAACGAAAAAAATGGATGAGAATCAATTAATGTATTTGGTAATATGTCATTTGATGAAGAACAGGAAATTAAAACTAGTG
ATTTAACTATTCAAATGCCTTCTTATGTAAAAAAAGAAGACAAAGAACTATTGGATAAAATTTATCAAGAACAACAATTA
GAATGCTCTTTACCAGAAGAAGTTTTAGACTCAAATTATATTGAACAAAATATGCCTAATGAAAATGATTTAAGTGCTGT
TGTTGAAGAACAACAATTAGATCCTCACAGACCTCGCTTTGTTTCAAGAAGAGTTTCAGAAAATAATCAAGTTGAAAGAG
TTGTTAAAAATCCTGATTTAAGACCTATCACTCAAAATAATGAGATGATTGTAAAATCAGAAAACATTTTAAATAGTAAT
GAAGAATTAAAAGTAGAAGAAATCAAAGATACAACTATTGATGGTGATGATACTTTCTTTGATGCTATTTATGAAGAACA
AGAAACTAAAAAAGTAAGCGAAACTTTAGAAGCTCTTGAAGCTTTAAATAAATATGAAGAAAAATACGATTTAAAAGAAG
AATCACCATTACAAAAAGAAGTTGAAACACCAATCATTTCAGCTCTTGAAGAACCTATTATTCAAGCGCCTCTTATTGAA
GAACCTGTTGTTGAAGAGCCACAAATTATAATAAATAAAAATTATAAACTTCCTCCAGTTGATGTTTTAGCTGTTATGGA
AAAAGACTACAACAAAGAAAGAGCAAACAAAGAAAACGCTGCTTTAAAAGCTCTAGCAATTGATGAGACTTTTAAACAAT
TTGGAGTTAAAGCAAAAGTTATTAATTCAATTATAGGACCAAGTGTTATGAAATTTGAAATTCAAGCAGAACCAGGTGTA
AAAGTTAATAGTATAACAAACCTAGAAAATGATTTAAAATTAGCTTTAGCAACTCAAAACATGCGTTTAGAAGCACCGAT
ACCTGGTAAAAATTTAATTGGTATTGAATTAGCTAATGCAAGTTCTGAAATGGTTTCAATGAGAGAAATTATTGAATCAA
TACCAAAAGAACAAGAAAATGAAAAATTACTTTTTGTTTTAGGAAAAAATGTTTTAGGTGAACCTTTAACTGCTCAATTA
AATAAAATGCCTCACTTACTTGTTGCTGGTTCAACAGGAAGTGGTAAATCAGTTATGATTAATGCATTAATTTGTTCAAT
TCTTTTAAGAGCAAAACCAAATGAAGTTAAATTCTTGATGATAGACCCTAAAAAAGTTGAACTTTCAGTTTATTCAAGAG
TGCCTCATATGTTAGCCCCAGTTATTTCAGATATGAAACAAGCTGCTAATGCATTGAAAATGGTTGTTGCTGAAATGGAA
AGACGTTATGAACTATTTATGAGCCTAGGTGTTAGAAACATTGATGGTTACAACAGAAAAGTAACAGGTTCTAAAAAAAT
GCCATTCCAAGTTATTATTATTGATGAACTTGCAGATTTAATGATGACTGGTGATAGAAAACAAGTTGAAGAATCAATTA
TGAGAATTACTCAAATGGCACGTGCTGCAGGTATTCACTTAATTGTTGCAACTCAAAGACCATCAACAGATGTTATTACA
GGAACAATTAAAACTAATATACCAACAAGAATTGCATTCGCTGTTACAACTGGAATTGACTCAAGAACAATTTTAGATTC
AACTGGAGCCGAAAACCTTTTAGGTAGAGGAGATATGTTATTTATGCCACCTGGTGGAGGAGATCTTATGAGAGCTCAAG
GTGCTTATTTAAGTGATGAAGAAATCGAAGAAATAGTAGACTTTACAATTGCTCAACAACAAGCAGTATATGCTGATGAA
TTTGATCAAGATAATCTAAAAACAGTTGGTTCTACTGATGAATTATATTCATTAGTTAAAGAATTTGTAATTGAAAAACA
AGACGCATCTTCATCATCTATTAAAGGTAAATTTAGAATTGCTGATGCTAGAGCAACAAATATTCTAAACCAATTAGAAG
ATGAAGGGGTTGTTGGGCCTAAAAATGGTTCAAGACCAAGAGAAGTATTAGTTAAAAAATAA

Upstream 100 bases:

>100_bases
AAATAAATAAATCACTATTTCTTGCTGAACTACTAAAACTTTAAAATAACACTAATTATTGCAAAATTGGTATAATTATA
TTATTGCAAAGGGTGATAAC

Downstream 100 bases:

>100_bases
AACCCTCAGTTTAGGGTTTTATTTTTCTAAGAGAATAGAAAGGAAAGCTATATGGAATTAAAAAATAAAGTTAGTAATTT
ACCAAGTAAACCTGGTTGTT

Product: DNA translocase (stage III sporulation protein E)

Products: NA

Alternate protein names: DNA translocase SpoIIIE; Stage III sporulation protein E [H]

Number of amino acids: Translated: 953; Mature: 953

Protein sequence:

>953_residues
MEKNKDEKFLANYEWNEEKTAAFVTTKQKRRNDSISWMVTGLVILFITVFSLGRITVIGQFLDDVFFNFIFGWFKYFIYI
VLFIVDLCIFSGIRFKFKKRFLFMVISSFILLCWLISLILFTQIIASKNENLNKLWQANFFAQMFNVYAKEWVDHSIFSG
QYYKEVIDYFLKTGSDGYFNLYSGGGITGTLMVGITSYLSIVGSYILLVFLMFINGMWIFTGDPIFLFKPKAKRKGKALR
ILTLKSKRNPNSKRPVAVQNEIHAEPKNEKNGWESINVFGNMSFDEEQEIKTSDLTIQMPSYVKKEDKELLDKIYQEQQL
ECSLPEEVLDSNYIEQNMPNENDLSAVVEEQQLDPHRPRFVSRRVSENNQVERVVKNPDLRPITQNNEMIVKSENILNSN
EELKVEEIKDTTIDGDDTFFDAIYEEQETKKVSETLEALEALNKYEEKYDLKEESPLQKEVETPIISALEEPIIQAPLIE
EPVVEEPQIIINKNYKLPPVDVLAVMEKDYNKERANKENAALKALAIDETFKQFGVKAKVINSIIGPSVMKFEIQAEPGV
KVNSITNLENDLKLALATQNMRLEAPIPGKNLIGIELANASSEMVSMREIIESIPKEQENEKLLFVLGKNVLGEPLTAQL
NKMPHLLVAGSTGSGKSVMINALICSILLRAKPNEVKFLMIDPKKVELSVYSRVPHMLAPVISDMKQAANALKMVVAEME
RRYELFMSLGVRNIDGYNRKVTGSKKMPFQVIIIDELADLMMTGDRKQVEESIMRITQMARAAGIHLIVATQRPSTDVIT
GTIKTNIPTRIAFAVTTGIDSRTILDSTGAENLLGRGDMLFMPPGGGDLMRAQGAYLSDEEIEEIVDFTIAQQQAVYADE
FDQDNLKTVGSTDELYSLVKEFVIEKQDASSSSIKGKFRIADARATNILNQLEDEGVVGPKNGSRPREVLVKK

Sequences:

>Translated_953_residues
MEKNKDEKFLANYE*NEEKTAAFVTTKQKRRNDSIS*MVTGLVILFITVFSLGRITVIGQFLDDVFFNFIFG*FKYFIYI
VLFIVDLCIFSGIRFKFKKRFLFMVISSFILLC*LISLILFTQIIASKNENLNKL*QANFFAQMFNVYAKE*VDHSIFSG
QYYKEVIDYFLKTGSDGYFNLYSGGGITGTLMVGITSYLSIVGSYILLVFLMFINGM*IFTGDPIFLFKPKAKRKGKALR
ILTLKSKRNPNSKRPVAVQNEIHAEPKNEKNG*ESINVFGNMSFDEEQEIKTSDLTIQMPSYVKKEDKELLDKIYQEQQL
ECSLPEEVLDSNYIEQNMPNENDLSAVVEEQQLDPHRPRFVSRRVSENNQVERVVKNPDLRPITQNNEMIVKSENILNSN
EELKVEEIKDTTIDGDDTFFDAIYEEQETKKVSETLEALEALNKYEEKYDLKEESPLQKEVETPIISALEEPIIQAPLIE
EPVVEEPQIIINKNYKLPPVDVLAVMEKDYNKERANKENAALKALAIDETFKQFGVKAKVINSIIGPSVMKFEIQAEPGV
KVNSITNLENDLKLALATQNMRLEAPIPGKNLIGIELANASSEMVSMREIIESIPKEQENEKLLFVLGKNVLGEPLTAQL
NKMPHLLVAGSTGSGKSVMINALICSILLRAKPNEVKFLMIDPKKVELSVYSRVPHMLAPVISDMKQAANALKMVVAEME
RRYELFMSLGVRNIDGYNRKVTGSKKMPFQVIIIDELADLMMTGDRKQVEESIMRITQMARAAGIHLIVATQRPSTDVIT
GTIKTNIPTRIAFAVTTGIDSRTILDSTGAENLLGRGDMLFMPPGGGDLMRAQGAYLSDEEIEEIVDFTIAQQQAVYADE
FDQDNLKTVGSTDELYSLVKEFVIEKQDASSSSIKGKFRIADARATNILNQLEDEGVVGPKNGSRPREVLVKK
>Mature_953_residues
MEKNKDEKFLANYE*NEEKTAAFVTTKQKRRNDSIS*MVTGLVILFITVFSLGRITVIGQFLDDVFFNFIFG*FKYFIYI
VLFIVDLCIFSGIRFKFKKRFLFMVISSFILLC*LISLILFTQIIASKNENLNKL*QANFFAQMFNVYAKE*VDHSIFSG
QYYKEVIDYFLKTGSDGYFNLYSGGGITGTLMVGITSYLSIVGSYILLVFLMFINGM*IFTGDPIFLFKPKAKRKGKALR
ILTLKSKRNPNSKRPVAVQNEIHAEPKNEKNG*ESINVFGNMSFDEEQEIKTSDLTIQMPSYVKKEDKELLDKIYQEQQL
ECSLPEEVLDSNYIEQNMPNENDLSAVVEEQQLDPHRPRFVSRRVSENNQVERVVKNPDLRPITQNNEMIVKSENILNSN
EELKVEEIKDTTIDGDDTFFDAIYEEQETKKVSETLEALEALNKYEEKYDLKEESPLQKEVETPIISALEEPIIQAPLIE
EPVVEEPQIIINKNYKLPPVDVLAVMEKDYNKERANKENAALKALAIDETFKQFGVKAKVINSIIGPSVMKFEIQAEPGV
KVNSITNLENDLKLALATQNMRLEAPIPGKNLIGIELANASSEMVSMREIIESIPKEQENEKLLFVLGKNVLGEPLTAQL
NKMPHLLVAGSTGSGKSVMINALICSILLRAKPNEVKFLMIDPKKVELSVYSRVPHMLAPVISDMKQAANALKMVVAEME
RRYELFMSLGVRNIDGYNRKVTGSKKMPFQVIIIDELADLMMTGDRKQVEESIMRITQMARAAGIHLIVATQRPSTDVIT
GTIKTNIPTRIAFAVTTGIDSRTILDSTGAENLLGRGDMLFMPPGGGDLMRAQGAYLSDEEIEEIVDFTIAQQQAVYADE
FDQDNLKTVGSTDELYSLVKEFVIEKQDASSSSIKGKFRIADARATNILNQLEDEGVVGPKNGSRPREVLVKK

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=466, Percent_Identity=45.0643776824034, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 106430; Mature: 106430

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNKDEKFLANYENEEKTAAFVTTKQKRRNDSISMVTGLVILFITVFSLGRITVIGQFL
CCCCCCCHHHHCCCCCCHHEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDVFFNFIFGFKYFIYIVLFIVDLCIFSGIRFKFKKRFLFMVISSFILLCLISLILFTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKNENLNKLQANFFAQMFNVYAKEVDHSIFSGQYYKEVIDYFLKTGSDGYFNLYSGGG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCC
ITGTLMVGITSYLSIVGSYILLVFLMFINGMIFTGDPIFLFKPKAKRKGKALRILTLKSK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCEEEEEEEECC
RNPNSKRPVAVQNEIHAEPKNEKNGESINVFGNMSFDEEQEIKTSDLTIQMPSYVKKEDK
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHH
ELLDKIYQEQQLECSLPEEVLDSNYIEQNMPNENDLSAVVEEQQLDPHRPRFVSRRVSEN
HHHHHHHHHHCCCCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCC
NQVERVVKNPDLRPITQNNEMIVKSENILNSNEELKVEEIKDTTIDGDDTFFDAIYEEQE
HHHHHHHCCCCCCEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
TKKVSETLEALEALNKYEEKYDLKEESPLQKEVETPIISALEEPIIQAPLIEEPVVEEPQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IIINKNYKLPPVDVLAVMEKDYNKERANKENAALKALAIDETFKQFGVKAKVINSIIGPS
EEEECCCCCCCHHHHHHHHHCCCHHHCCCHHHHEEEHHHHHHHHHHCCHHHHHHHHHCCC
VMKFEIQAEPGVKVNSITNLENDLKLALATQNMRLEAPIPGKNLIGIELANASSEMVSMR
EEEEEEECCCCCEEECCCCCCCCEEEEEEECCCEEECCCCCCCEEEEEECCCHHHHHHHH
EIIESIPKEQENEKLLFVLGKNVLGEPLTAQLNKMPHLLVAGSTGSGKSVMINALICSIL
HHHHHCCCCCCCCEEEEEECCHHHCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
LRAKPNEVKFLMIDPKKVELSVYSRVPHMLAPVISDMKQAANALKMVVAEMERRYELFMS
HHCCCCCEEEEEECCCEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVRNIDGYNRKVTGSKKMPFQVIIIDELADLMMTGDRKQVEESIMRITQMARAAGIHLI
HCCCCCCCCCCEECCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEE
VATQRPSTDVITGTIKTNIPTRIAFAVTTGIDSRTILDSTGAENLLGRGDMLFMPPGGGD
EEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCEEECCCCCHHHCCCCCEEEECCCCCC
LMRAQGAYLSDEEIEEIVDFTIAQQQAVYADEFDQDNLKTVGSTDELYSLVKEFVIEKQD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
ASSSSIKGKFRIADARATNILNQLEDEGVVGPKNGSRPREVLVKK
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MEKNKDEKFLANYENEEKTAAFVTTKQKRRNDSISMVTGLVILFITVFSLGRITVIGQFL
CCCCCCCHHHHCCCCCCHHEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHH
DDVFFNFIFGFKYFIYIVLFIVDLCIFSGIRFKFKKRFLFMVISSFILLCLISLILFTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IASKNENLNKLQANFFAQMFNVYAKEVDHSIFSGQYYKEVIDYFLKTGSDGYFNLYSGGG
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCC
ITGTLMVGITSYLSIVGSYILLVFLMFINGMIFTGDPIFLFKPKAKRKGKALRILTLKSK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCCEEEEEEEECC
RNPNSKRPVAVQNEIHAEPKNEKNGESINVFGNMSFDEEQEIKTSDLTIQMPSYVKKEDK
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHHH
ELLDKIYQEQQLECSLPEEVLDSNYIEQNMPNENDLSAVVEEQQLDPHRPRFVSRRVSEN
HHHHHHHHHHCCCCCCCHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHCCC
NQVERVVKNPDLRPITQNNEMIVKSENILNSNEELKVEEIKDTTIDGDDTFFDAIYEEQE
HHHHHHHCCCCCCEECCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
TKKVSETLEALEALNKYEEKYDLKEESPLQKEVETPIISALEEPIIQAPLIEEPVVEEPQ
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
IIINKNYKLPPVDVLAVMEKDYNKERANKENAALKALAIDETFKQFGVKAKVINSIIGPS
EEEECCCCCCCHHHHHHHHHCCCHHHCCCHHHHEEEHHHHHHHHHHCCHHHHHHHHHCCC
VMKFEIQAEPGVKVNSITNLENDLKLALATQNMRLEAPIPGKNLIGIELANASSEMVSMR
EEEEEEECCCCCEEECCCCCCCCEEEEEEECCCEEECCCCCCCEEEEEECCCHHHHHHHH
EIIESIPKEQENEKLLFVLGKNVLGEPLTAQLNKMPHLLVAGSTGSGKSVMINALICSIL
HHHHHCCCCCCCCEEEEEECCHHHCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHH
LRAKPNEVKFLMIDPKKVELSVYSRVPHMLAPVISDMKQAANALKMVVAEMERRYELFMS
HHCCCCCEEEEEECCCEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGVRNIDGYNRKVTGSKKMPFQVIIIDELADLMMTGDRKQVEESIMRITQMARAAGIHLI
HCCCCCCCCCCEECCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEE
VATQRPSTDVITGTIKTNIPTRIAFAVTTGIDSRTILDSTGAENLLGRGDMLFMPPGGGD
EEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCEEECCCCCHHHCCCCCEEEECCCCCC
LMRAQGAYLSDEEIEEIVDFTIAQQQAVYADEFDQDNLKTVGSTDELYSLVKEFVIEKQD
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
ASSSSIKGKFRIADARATNILNQLEDEGVVGPKNGSRPREVLVKK
CCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3129532; 2507870; 9384377; 8160014; 10588743; 11062134; 11778051 [H]