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The map label for this gene is czcD [H]

Identifier: 50086351

GI number: 50086351

Start: 3282644

End: 3283567

Strand: Reverse

Name: czcD [H]

Synonym: ACIAD3374

Alternate gene names: 50086351

Gene position: 3283567-3282644 (Counterclockwise)

Preceding gene: 50086352

Following gene: 50086347

Centisome position: 91.25

GC content: 43.51

Gene sequence:

>924_bases
ATGAGTGGACAGCACGGGCATGATCATAGCCATGCGGTTGTTACACAAGGAAATGCCAAAAAGCTTACGATCGCATTGTC
ACTCACCGTGACTTTTCTGATTGTTGAAGTGGTCGCAGGGTTTATCACGCAAAGTCTGGCATTGTTGTCGGATGCCGCAC
ATATGTTCACTGATGCCGCTGCTCTGGCAATCGCATTAGCCGCAATTCAAGTGGCCAAACGTCCAGCAGATGACAAACGG
ACTTTTGGCTATCAGCGCTTTGAAATTCTAGCTGCCTTATTTAATGCATCTATGCTCTTTATGGTTGCAATCTATATTTT
GTATGAGGCGTATCAGCGTTTTACTCATCCGCCTGAAATTCAGAGTTTGGGCATGTTACTGGTTGCAGTCATTGGACTGA
TCATCAATCTAATCTCAATGAAAATTCTGGTCTCCAGTGCTCAGGATAGTCTGAATGTAAAAGGGGCTTACCTTGAAGTT
TTAAGTGATGCGCTGGGCTCGGTTGGTGTGATTCTGGGTGCATTGGTTATCTATTTTACCCAGTGGTACTGGGTCGATAC
ACTGGTTGCGGTCTTGATTGGATTTTGGGTGCTTCCACGAACATGGATTCTGCTGAAACAAAGTATTAATATTTTACTGG
AAGGTGTTCCTGAAGAAGTTGACATTGAGAAGCTTAGAGATGATTTGTTGGCTCTTGAAGGCGTTGAAAGTATTCATCAG
CTTAAAGTCTGGGCCATTACATCCAAAAATGTACATCTGACGGTGCATCTGTTTGCACCACAGGCAGATCGTAATCGTCT
GTATCGCACGGCCTATGAAATGCTTTCACATGAGCATGGCATTGCAGAAATTACTTTGCAGATTGAAGAAGATGAATGTT
TGGCACATTCACATACGCATATAGAAAAAAACCATCAGCACTGA

Upstream 100 bases:

>100_bases
TATGAGTCTTCATGATATATCGTGTGTCATGAAGGCTTTAAAATAAAAAGCGTTATCCAGCGCAACTTTCGATTTAAATT
TCTGTTGTAAGGAGTCTACT

Downstream 100 bases:

>100_bases
CTGATGGTTTTTAAAAATATTCTTGAGACCTTAAGTTTAAATTTGCCATTCATGATGACATTCGCGGCACTTCCAGTACT
TTTGCGATTGCATGAACGCT

Product: cation efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSGQHGHDHSHAVVTQGNAKKLTIALSLTVTFLIVEVVAGFITQSLALLSDAAHMFTDAAALAIALAAIQVAKRPADDKR
TFGYQRFEILAALFNASMLFMVAIYILYEAYQRFTHPPEIQSLGMLLVAVIGLIINLISMKILVSSAQDSLNVKGAYLEV
LSDALGSVGVILGALVIYFTQWYWVDTLVAVLIGFWVLPRTWILLKQSINILLEGVPEEVDIEKLRDDLLALEGVESIHQ
LKVWAITSKNVHLTVHLFAPQADRNRLYRTAYEMLSHEHGIAEITLQIEEDECLAHSHTHIEKNHQH

Sequences:

>Translated_307_residues
MSGQHGHDHSHAVVTQGNAKKLTIALSLTVTFLIVEVVAGFITQSLALLSDAAHMFTDAAALAIALAAIQVAKRPADDKR
TFGYQRFEILAALFNASMLFMVAIYILYEAYQRFTHPPEIQSLGMLLVAVIGLIINLISMKILVSSAQDSLNVKGAYLEV
LSDALGSVGVILGALVIYFTQWYWVDTLVAVLIGFWVLPRTWILLKQSINILLEGVPEEVDIEKLRDDLLALEGVESIHQ
LKVWAITSKNVHLTVHLFAPQADRNRLYRTAYEMLSHEHGIAEITLQIEEDECLAHSHTHIEKNHQH
>Mature_306_residues
SGQHGHDHSHAVVTQGNAKKLTIALSLTVTFLIVEVVAGFITQSLALLSDAAHMFTDAAALAIALAAIQVAKRPADDKRT
FGYQRFEILAALFNASMLFMVAIYILYEAYQRFTHPPEIQSLGMLLVAVIGLIINLISMKILVSSAQDSLNVKGAYLEVL
SDALGSVGVILGALVIYFTQWYWVDTLVAVLIGFWVLPRTWILLKQSINILLEGVPEEVDIEKLRDDLLALEGVESIHQL
KVWAITSKNVHLTVHLFAPQADRNRLYRTAYEMLSHEHGIAEITLQIEEDECLAHSHTHIEKNHQH

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=302, Percent_Identity=33.112582781457, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI21359890, Length=301, Percent_Identity=29.2358803986711, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI64762489, Length=316, Percent_Identity=29.4303797468354, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI21361112, Length=298, Percent_Identity=30.5369127516779, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI289803013, Length=311, Percent_Identity=29.2604501607717, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI289803009, Length=311, Percent_Identity=29.2604501607717, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI289803007, Length=311, Percent_Identity=29.2604501607717, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI289803003, Length=311, Percent_Identity=29.2604501607717, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI20070323, Length=330, Percent_Identity=24.8484848484848, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI14210520, Length=217, Percent_Identity=30.4147465437788, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI222080086, Length=132, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40255009, Length=132, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI52351208, Length=134, Percent_Identity=35.8208955223881, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI52352803, Length=125, Percent_Identity=43.2, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1786966, Length=279, Percent_Identity=40.1433691756272, Blast_Score=164, Evalue=5e-42,
Organism=Escherichia coli, GI1790349, Length=214, Percent_Identity=25.2336448598131, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193210990, Length=312, Percent_Identity=31.0897435897436, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17555794, Length=317, Percent_Identity=29.6529968454259, Blast_Score=141, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32564488, Length=304, Percent_Identity=30.9210526315789, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17555796, Length=305, Percent_Identity=29.8360655737705, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17550440, Length=131, Percent_Identity=33.587786259542, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17550442, Length=131, Percent_Identity=33.587786259542, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323899, Length=137, Percent_Identity=39.4160583941606, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320411, Length=169, Percent_Identity=31.9526627218935, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324892, Length=131, Percent_Identity=38.9312977099237, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24583858, Length=325, Percent_Identity=27.0769230769231, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24656728, Length=336, Percent_Identity=26.7857142857143, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656724, Length=336, Percent_Identity=26.7857142857143, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656720, Length=336, Percent_Identity=26.7857142857143, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24656715, Length=336, Percent_Identity=26.7857142857143, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357035, Length=336, Percent_Identity=26.7857142857143, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24645863, Length=128, Percent_Identity=37.5, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24585900, Length=136, Percent_Identity=33.0882352941176, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585898, Length=136, Percent_Identity=33.0882352941176, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24585896, Length=136, Percent_Identity=33.0882352941176, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19921672, Length=136, Percent_Identity=33.0882352941176, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24584409, Length=140, Percent_Identity=31.4285714285714, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28574430, Length=137, Percent_Identity=32.1167883211679, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34134; Mature: 34003

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQHGHDHSHAVVTQGNAKKLTIALSLTVTFLIVEVVAGFITQSLALLSDAAHMFTDAA
CCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIALAAIQVAKRPADDKRTFGYQRFEILAALFNASMLFMVAIYILYEAYQRFTHPPEI
HHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QSLGMLLVAVIGLIINLISMKILVSSAQDSLNVKGAYLEVLSDALGSVGVILGALVIYFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QWYWVDTLVAVLIGFWVLPRTWILLKQSINILLEGVPEEVDIEKLRDDLLALEGVESIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LKVWAITSKNVHLTVHLFAPQADRNRLYRTAYEMLSHEHGIAEITLQIEEDECLAHSHTH
EEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
IEKNHQH
CCCCCCC
>Mature Secondary Structure 
SGQHGHDHSHAVVTQGNAKKLTIALSLTVTFLIVEVVAGFITQSLALLSDAAHMFTDAA
CCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAIALAAIQVAKRPADDKRTFGYQRFEILAALFNASMLFMVAIYILYEAYQRFTHPPEI
HHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
QSLGMLLVAVIGLIINLISMKILVSSAQDSLNVKGAYLEVLSDALGSVGVILGALVIYFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QWYWVDTLVAVLIGFWVLPRTWILLKQSINILLEGVPEEVDIEKLRDDLLALEGVESIHQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
LKVWAITSKNVHLTVHLFAPQADRNRLYRTAYEMLSHEHGIAEITLQIEEDECLAHSHTH
EEEEEEECCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHH
IEKNHQH
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]