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The map label for this gene is comP [H]

Identifier: 50086319

GI number: 50086319

Start: 3240883

End: 3241326

Strand: Reverse

Name: comP [H]

Synonym: ACIAD3338

Alternate gene names: 50086319

Gene position: 3241326-3240883 (Counterclockwise)

Preceding gene: 50086320

Following gene: 50086318

Centisome position: 90.07

GC content: 40.54

Gene sequence:

>444_bases
ATGAATGCACAAAAGGGTTTTACCTTAATTGAATTGATGATTGTCATTGCGATCATTGGTATTTTGGCAGCGATTGCGAT
TCCTGCTTATACAGATTATACAGTCCGTGCACGTGTTTCTGAAGGATTAACAGCAGCATCATCCATGAAAACGACGGTTT
CAGAAAATATTTTAAATGCAGGTGCATTAGTTGCAGGTACTCCTTCAACTGCAGGCTCATCTTGCGTTGGAGTCCAAGAA
ATTTCAGCAAGTAATGCCACTACGAACGTAGCAACTGCTACATGTGGAGCGAGTAGTGCTGGACAAATCATTGTAACTAT
GGATACTACTAAGGCTAAGGGCGCTAATATAACATTAACGCCAACATATGCTAGTGGCGCTGTAACATGGAAATGTACGA
CAACTTCTGATAAAAAATATGTACCATCAGAATGTCGTGGTTGA

Upstream 100 bases:

>100_bases
TATTATTTAAAAAAATATTTTTAAAACTTGGCACACTCTATGCAATAACTTATACAGCGACCAACGCGAAATAAAATCAC
AACATTGGTGGAGAAATTTT

Downstream 100 bases:

>100_bases
TAGTAGTACTATATGGCTTTAAAAGAAGAACTTTTATAAGTTCTTCTTTAAATTATAAAAAATGAATAGTATTTTTAAAA
AAATCAAAAATTACACGATA

Product: competence factor involved in DNA binding and uptake

Products: NA

Alternate protein names: L-pilin [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MNAQKGFTLIELMIVIAIIGILAAIAIPAYTDYTVRARVSEGLTAASSMKTTVSENILNAGALVAGTPSTAGSSCVGVQE
ISASNATTNVATATCGASSAGQIIVTMDTTKAKGANITLTPTYASGAVTWKCTTTSDKKYVPSECRG

Sequences:

>Translated_147_residues
MNAQKGFTLIELMIVIAIIGILAAIAIPAYTDYTVRARVSEGLTAASSMKTTVSENILNAGALVAGTPSTAGSSCVGVQE
ISASNATTNVATATCGASSAGQIIVTMDTTKAKGANITLTPTYASGAVTWKCTTTSDKKYVPSECRG
>Mature_147_residues
MNAQKGFTLIELMIVIAIIGILAAIAIPAYTDYTVRARVSEGLTAASSMKTTVSENILNAGALVAGTPSTAGSSCVGVQE
ISASNATTNVATATCGASSAGQIIVTMDTTKAKGANITLTPTYASGAVTWKCTTTSDKKYVPSECRG

Specific function: This protein is the predominant Neisseria surface antigen, which allows adhesion of the bacterium to various host cells [H]

COG id: COG4969

COG function: function code NU; Tfp pilus assembly protein, major pilin PilA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N-Me-Phe pilin family [H]

Homologues:

Organism=Escherichia coli, GI1786297, Length=141, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001082
- InterPro:   IPR012902
- InterPro:   IPR001120 [H]

Pfam domain/function: PF07963 N_methyl; PF00114 Pilin [H]

EC number: NA

Molecular weight: Translated: 14872; Mature: 14872

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS00409 PROKAR_NTER_METHYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAQKGFTLIELMIVIAIIGILAAIAIPAYTDYTVRARVSEGLTAASSMKTTVSENILNA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
GALVAGTPSTAGSSCVGVQEISASNATTNVATATCGASSAGQIIVTMDTTKAKGANITLT
CEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEE
PTYASGAVTWKCTTTSDKKYVPSECRG
ECCCCCEEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNAQKGFTLIELMIVIAIIGILAAIAIPAYTDYTVRARVSEGLTAASSMKTTVSENILNA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCC
GALVAGTPSTAGSSCVGVQEISASNATTNVATATCGASSAGQIIVTMDTTKAKGANITLT
CEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCEEEEE
PTYASGAVTWKCTTTSDKKYVPSECRG
ECCCCCEEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906968 [H]