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The map label for this gene is hflX [H]

Identifier: 50086023

GI number: 50086023

Start: 2933543

End: 2934877

Strand: Direct

Name: hflX [H]

Synonym: ACIAD3005

Alternate gene names: 50086023

Gene position: 2933543-2934877 (Clockwise)

Preceding gene: 50086021

Following gene: 50086024

Centisome position: 81.52

GC content: 44.19

Gene sequence:

>1335_bases
GTGGAATCATTAGATCAAGATCAAGGCAAAGAACGAGTTATTTTGGTCAGTGTGAGTGTCAATATACTGGATGACCTCGA
TGCAGAAGAATTTGCATTACTTGCATCTTCCGCAGGTGCAGAACGTTTAGAGCACATCTATGCACAACGTGTAAAACCTG
ATGCCAAATTGTTTATTGGTTCTGGTAAAGCCGAAGAAATTGCAGAGCGTGTAGAAGCACTGGATGCTAGTCTGGTTATT
TTTGATCACGCACTTTCCCCCGCTCAAGAACGAAATCTTGAGAAAATTATGAAATGTCGTGTGATTGACCGAACGGGTCT
GATTCTAGACATCTTTGCACAACGTGCTCGTACACATGAAGGTAAACTGCAAGTCGAACTGGCTCAGCTGAAGCACTTAT
CCACACGACTAGTACGTGGCTGGTCTGGAGGTTTTGAGCAACAAAAAGGCGGAATTGGCTTACGTGGCCCAGGTGAAACC
CAGCTTGAAACAGATCGCCGCTTGATTCGTATCCGAATGATCCAGCTCAAAGATAAACTGGATAAAGTTCAACAAACACG
TTTGCAAGGTCGTGCGGCGCGTCAAAAAGCTGCCATCCCAACCGTATCACTGGTCGGTTATACCAACGCAGGTAAATCTA
CCCTGTTTAATCATCTGGCCAATAGCGATGTTTATGCTGCCGATCAACTTTTTGCTACTCTCGATCCTACGCTTCGTCGC
TTAGATTGGGATGGAATCGGTACCGTCGTATTAGCTGATACTGTAGGTTTTGTACGTAATTTGCAGCATGATCTAATCGA
GTCATTCAAAGCAACTTTAGAAGAAACTCTTGAAGCGACTTTGCTTTTGCATATTATCGACAGCAGTAGTCCCGACATGC
TCGAACAGATTGAAGCTGTTGAAGGCGTACTCAAAGAAATAGGAGCAGACGCACCTGTATTACGGGTATACAACAAAATT
GATGTCAGCGGTGATGAAGCAAAAATTATCTATGCACGTCCGCACGAACCAGAACGTGTTTATGTGTCGGCACACTCGGG
TGCAGGAATTGATCTGCTGAAAAAGGCTGTACAAGAATGTCTAATGGGACAGCGTCAGGCCTTTGATCTGATCTTAAAAC
CTATACATGGCAAACTGCGTACGCAACTTTATAATCTTAATGTGATTGATTCCGAGCATTTTGACGACCAAGGTCAGCTC
CATCTACATGTGGTCATGGCCCCACAAAAGCTGGAACAATTGATTCGACAAGCGCATTTATCACTGGATGAGATTCTGGG
AGAACAAGCACAAGGTTTCAAACGACCACTAGAAGAGTTTGAAATCAAAAGCTAG

Upstream 100 bases:

>100_bases
TTCATAGCCTGATTTAAGTAGATGCCTAGAATAAGATTCGCTTGAGTAACAGGATTATTCTAGAATAATCCTTTTCGCTT
AAACGAGAGTTGAATCATCT

Downstream 100 bases:

>100_bases
ATCGGTTAAAACTTGATAAATCAAATTTTAATAAGATTTCATTAATGGATTTGTTTAGACAGATTGACTGGTTTGCCTGG
CTTGGCACAATTGCCCTGAT

Product: GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MESLDQDQGKERVILVSVSVNILDDLDAEEFALLASSAGAERLEHIYAQRVKPDAKLFIGSGKAEEIAERVEALDASLVI
FDHALSPAQERNLEKIMKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLVRGWSGGFEQQKGGIGLRGPGET
QLETDRRLIRIRMIQLKDKLDKVQQTRLQGRAARQKAAIPTVSLVGYTNAGKSTLFNHLANSDVYAADQLFATLDPTLRR
LDWDGIGTVVLADTVGFVRNLQHDLIESFKATLEETLEATLLLHIIDSSSPDMLEQIEAVEGVLKEIGADAPVLRVYNKI
DVSGDEAKIIYARPHEPERVYVSAHSGAGIDLLKKAVQECLMGQRQAFDLILKPIHGKLRTQLYNLNVIDSEHFDDQGQL
HLHVVMAPQKLEQLIRQAHLSLDEILGEQAQGFKRPLEEFEIKS

Sequences:

>Translated_444_residues
MESLDQDQGKERVILVSVSVNILDDLDAEEFALLASSAGAERLEHIYAQRVKPDAKLFIGSGKAEEIAERVEALDASLVI
FDHALSPAQERNLEKIMKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLVRGWSGGFEQQKGGIGLRGPGET
QLETDRRLIRIRMIQLKDKLDKVQQTRLQGRAARQKAAIPTVSLVGYTNAGKSTLFNHLANSDVYAADQLFATLDPTLRR
LDWDGIGTVVLADTVGFVRNLQHDLIESFKATLEETLEATLLLHIIDSSSPDMLEQIEAVEGVLKEIGADAPVLRVYNKI
DVSGDEAKIIYARPHEPERVYVSAHSGAGIDLLKKAVQECLMGQRQAFDLILKPIHGKLRTQLYNLNVIDSEHFDDQGQL
HLHVVMAPQKLEQLIRQAHLSLDEILGEQAQGFKRPLEEFEIKS
>Mature_444_residues
MESLDQDQGKERVILVSVSVNILDDLDAEEFALLASSAGAERLEHIYAQRVKPDAKLFIGSGKAEEIAERVEALDASLVI
FDHALSPAQERNLEKIMKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLKHLSTRLVRGWSGGFEQQKGGIGLRGPGET
QLETDRRLIRIRMIQLKDKLDKVQQTRLQGRAARQKAAIPTVSLVGYTNAGKSTLFNHLANSDVYAADQLFATLDPTLRR
LDWDGIGTVVLADTVGFVRNLQHDLIESFKATLEETLEATLLLHIIDSSSPDMLEQIEAVEGVLKEIGADAPVLRVYNKI
DVSGDEAKIIYARPHEPERVYVSAHSGAGIDLLKKAVQECLMGQRQAFDLILKPIHGKLRTQLYNLNVIDSEHFDDQGQL
HLHVVMAPQKLEQLIRQAHLSLDEILGEQAQGFKRPLEEFEIKS

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=204, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124267, Length=204, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124171, Length=204, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310124169, Length=204, Percent_Identity=37.2549019607843, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI310133116, Length=212, Percent_Identity=36.7924528301887, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI310133118, Length=212, Percent_Identity=36.7924528301887, Blast_Score=115, Evalue=9e-26,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=55.868544600939, Blast_Score=443, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17561038, Length=245, Percent_Identity=31.8367346938775, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24650079, Length=384, Percent_Identity=30.2083333333333, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49553; Mature: 49553

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLDQDQGKERVILVSVSVNILDDLDAEEFALLASSAGAERLEHIYAQRVKPDAKLFIG
CCCCCCCCCCCEEEEEEEEEEHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEC
SGKAEEIAERVEALDASLVIFDHALSPAQERNLEKIMKCRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GKLQVELAQLKHLSTRLVRGWSGGFEQQKGGIGLRGPGETQLETDRRLIRIRMIQLKDKL
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DKVQQTRLQGRAARQKAAIPTVSLVGYTNAGKSTLFNHLANSDVYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHH
LDWDGIGTVVLADTVGFVRNLQHDLIESFKATLEETLEATLLLHIIDSSSPDMLEQIEAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
EGVLKEIGADAPVLRVYNKIDVSGDEAKIIYARPHEPERVYVSAHSGAGIDLLKKAVQEC
HHHHHHHCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHH
LMGQRQAFDLILKPIHGKLRTQLYNLNVIDSEHFDDQGQLHLHVVMAPQKLEQLIRQAHL
HCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHC
SLDEILGEQAQGFKRPLEEFEIKS
CHHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MESLDQDQGKERVILVSVSVNILDDLDAEEFALLASSAGAERLEHIYAQRVKPDAKLFIG
CCCCCCCCCCCEEEEEEEEEEHHHCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEC
SGKAEEIAERVEALDASLVIFDHALSPAQERNLEKIMKCRVIDRTGLILDIFAQRARTHE
CCCHHHHHHHHHHHCCHHEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
GKLQVELAQLKHLSTRLVRGWSGGFEQQKGGIGLRGPGETQLETDRRLIRIRMIQLKDKL
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
DKVQQTRLQGRAARQKAAIPTVSLVGYTNAGKSTLFNHLANSDVYAADQLFATLDPTLRR
HHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHH
LDWDGIGTVVLADTVGFVRNLQHDLIESFKATLEETLEATLLLHIIDSSSPDMLEQIEAV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHH
EGVLKEIGADAPVLRVYNKIDVSGDEAKIIYARPHEPERVYVSAHSGAGIDLLKKAVQEC
HHHHHHHCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHH
LMGQRQAFDLILKPIHGKLRTQLYNLNVIDSEHFDDQGQLHLHVVMAPQKLEQLIRQAHL
HCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHC
SLDEILGEQAQGFKRPLEEFEIKS
CHHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]