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The map label for this gene is groES

Identifier: 50085882

GI number: 50085882

Start: 2776997

End: 2777287

Strand: Reverse

Name: groES

Synonym: ACIAD2839

Alternate gene names: 50085882

Gene position: 2777287-2776997 (Counterclockwise)

Preceding gene: 50085883

Following gene: 50085881

Centisome position: 77.18

GC content: 41.24

Gene sequence:

>291_bases
ATGAGCAACATTCGTCCATTACATGACCGTGTAGTAATTCGTCGTGTTGAAGAAGAAACAAAAACGGCTGGCGGTATCTT
ATTGCCAGGTTCTGCTGCTGAAAAACCTGCCCAAGGTGAAGTGATTGCAGTAGGTAATGGTCAAATCACTGAGAATGGCG
TACGTGCACTTGATGTTAAAGCAGGTGACAAAGTGTTATTTGGTACTTATGCAGGTACAACTGTAAAAGTAAACGGTGAA
GAATTCCTCATCATGAAAGAATCTGACATTTTAGCTGTTCTTGAAGGCTAA

Upstream 100 bases:

>100_bases
CCCCAAAACAGTGTCATCAAATTCATTTTGATGGTTGCTAAAGGAATAATGACGGCAAGCATCATTCATTAAATATAGAC
TTAGTCTGATGGAGTTATTT

Downstream 100 bases:

>100_bases
ATTTCACTTAACTCATTGATAAATCAGATCAAGCATTGATAGAAAAATTTGGAGTATAGAATGTCAGCTAAAGACGTAAA
ATTTGGTGATTCAGCGCGTT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 95

Protein sequence:

>96_residues
MSNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVKAGDKVLFGTYAGTTVKVNGE
EFLIMKESDILAVLEG

Sequences:

>Translated_96_residues
MSNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVKAGDKVLFGTYAGTTVKVNGE
EFLIMKESDILAVLEG
>Mature_95_residues
SNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVKAGDKVLFGTYAGTTVKVNGEE
FLIMKESDILAVLEG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=62.1052631578947, Blast_Score=111, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17555568, Length=96, Percent_Identity=43.75, Blast_Score=78, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=41.304347826087, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21358317, Length=102, Percent_Identity=46.078431372549, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356029, Length=101, Percent_Identity=43.5643564356436, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_ACIAD (Q6F8P5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047392.1
- ProteinModelPortal:   Q6F8P5
- SMR:   Q6F8P5
- STRING:   Q6F8P5
- GeneID:   2878147
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2839
- NMPDR:   fig|62977.3.peg.2585
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   FGQYAGQ
- PhylomeDB:   Q6F8P5
- ProtClustDB:   PRK00364
- BioCyc:   ASP62977:ACIAD2839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10161; Mature: 10030

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVK
CCCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCEECCCCEEEEEEC
AGDKVLFGTYAGTTVKVNGEEFLIMKESDILAVLEG
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure 
SNIRPLHDRVVIRRVEEETKTAGGILLPGSAAEKPAQGEVIAVGNGQITENGVRALDVK
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCEEEECCCEECCCCEEEEEEC
AGDKVLFGTYAGTTVKVNGEEFLIMKESDILAVLEG
CCCEEEEEECCCCEEEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA