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The map label for this gene is aspC [H]

Identifier: 50085649

GI number: 50085649

Start: 2533408

End: 2534640

Strand: Direct

Name: aspC [H]

Synonym: ACIAD2574

Alternate gene names: 50085649

Gene position: 2533408-2534640 (Clockwise)

Preceding gene: 50085647

Following gene: 50085661

Centisome position: 70.4

GC content: 42.66

Gene sequence:

>1233_bases
GTGGACGTACGTCTGTCTGATCGTGTGAATGCCATCAAACCGTCCCCAACTCTTGCTGTTACCAATAAAGCGGCTGAGCT
TAAAGCTGCGGGTAAAAATGTGATTGGTTTGGGCGCAGGTGAACCAGATTTTGATACCCCGCAACACATCAAAGATGCTG
CTATTGAAGCCATTAATAATGGTTTTACCAAATACACAGCAGTTGATGGTACGCCAGGCCTGAAAAAAGCAATTATTGCA
AAATTTAAACGTGATAATAATCTTGACTACCAAGCAAACCAGATTCTGGTTTCATGTGGTGGTAAGCAATCATTCTTTAA
CCTTGCATTAGCATTGTTAAATAAAGGTGATGAAGTCATTATTCCTGCACCTTACTGGGTCAGCTATCCAGATATGGTAA
TTATTGCGGAAGGCACCCCTGTTATTGTGAAATGTGGTGAAGATCAACGTTTTAAAATCACGCCAGAACAGCTTGAAGCA
GCAATCACTCCAAACACGCGCTTATTGGTATTAAACAGCCCTTCAAACCCGACAGGTATGATTTACACCAAAGCTGAGCT
TGAAGCATTGGCTGACGTTTTGCGTAAGCACCCACAAGTATATATCGCATCTGACGACATGTATGAACCAATCCGCTGGG
AAGATGAGTTCTACAACATTGCCACTGTTGCACCAGATCTTTACGATCGTACACTGGTATTAAATGGCGTATCTAAAGCC
TATGCGATGACAGGATGGCGTATTGGTTATGCAGCAGGTCCTGCAAAAATCATTGGTGCCATGAAAAAAATCCAGTCTCA
ATCGACATCTAATCCAACGTCAATTTCACAAGTGGCTGCTGAAGCTGCATTGAATGGCCCACAAGATGTTCTTGAGCCAA
TGATTGAAGCATTTAAACGTCGTCATGACCTCGTAGTAAACGGTTTAAATGAAATTCATGGTATTTCTTGCTTACCAGCA
GACGGCGCATTTTATGCTTATGCCAATATCCGCCCTCTCATTCGTGCGAAAGGTTTGAAATCTTGCACAGAATTTTCTGA
ATGGTTACTCGAAGAAACAGGCGTAGCCGTAGTACCAGGTGATGCATTTGGTTTGGGTGGCTTTATGCGTATTTCGTATG
CAACAGCAGATGACGTTTTAGTCGATGCGCTAGCACGTATCAAAAAAGCGGCAGACTCAATTGAAGGTATTGATGCTGCA
ATTGCTTCCATCGAAGCTGAAAAGAATGCTTAA

Upstream 100 bases:

>100_bases
AGATTTTTTGATTTTTGTTTTGATAATGAGACACCAGTAACTCATTTTGGGCTAAGATAGTGTGCTTTTATTTTTTAATC
CCATAAGAAGGAATATTGCC

Downstream 100 bases:

>100_bases
TCGTATCTAAATAAAAAAACCTATCTTCGGATAGGTTTTTTTATTTCATATTTTGTTCAAACTATTCTGTACGACTCAAT
TTTGTATGGCACACAGGTAT

Product: aspartate aminotransferase A

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KFKRDNNLDYQANQILVSCGGKQSFFNLALALLNKGDEVIIPAPYWVSYPDMVIIAEGTPVIVKCGEDQRFKITPEQLEA
AITPNTRLLVLNSPSNPTGMIYTKAELEALADVLRKHPQVYIASDDMYEPIRWEDEFYNIATVAPDLYDRTLVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLEPMIEAFKRRHDLVVNGLNEIHGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADDVLVDALARIKKAADSIEGIDAA
IASIEAEKNA

Sequences:

>Translated_410_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KFKRDNNLDYQANQILVSCGGKQSFFNLALALLNKGDEVIIPAPYWVSYPDMVIIAEGTPVIVKCGEDQRFKITPEQLEA
AITPNTRLLVLNSPSNPTGMIYTKAELEALADVLRKHPQVYIASDDMYEPIRWEDEFYNIATVAPDLYDRTLVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLEPMIEAFKRRHDLVVNGLNEIHGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADDVLVDALARIKKAADSIEGIDAA
IASIEAEKNA
>Mature_410_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KFKRDNNLDYQANQILVSCGGKQSFFNLALALLNKGDEVIIPAPYWVSYPDMVIIAEGTPVIVKCGEDQRFKITPEQLEA
AITPNTRLLVLNSPSNPTGMIYTKAELEALADVLRKHPQVYIASDDMYEPIRWEDEFYNIATVAPDLYDRTLVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLEPMIEAFKRRHDLVVNGLNEIHGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADDVLVDALARIKKAADSIEGIDAA
IASIEAEKNA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=27.2040302267003, Blast_Score=149, Evalue=5e-36,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=27.2040302267003, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI95147551, Length=384, Percent_Identity=25.78125, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881279, Length=384, Percent_Identity=25.78125, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI169881281, Length=380, Percent_Identity=23.1578947368421, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4507369, Length=397, Percent_Identity=24.4332493702771, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.3062330623306, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.3062330623306, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=27.1739130434783, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1788722, Length=413, Percent_Identity=31.9612590799031, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788627, Length=384, Percent_Identity=29.6875, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=408, Percent_Identity=28.6764705882353, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71994476, Length=408, Percent_Identity=28.6764705882353, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=417, Percent_Identity=26.6187050359712, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=23.2620320855615, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71981209, Length=364, Percent_Identity=23.3516483516484, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=26.2626262626263, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28573069, Length=361, Percent_Identity=25.207756232687, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24646114, Length=361, Percent_Identity=25.207756232687, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573067, Length=361, Percent_Identity=25.207756232687, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28573065, Length=361, Percent_Identity=25.207756232687, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=23.2984293193717, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24641770, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641760, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641768, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641766, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24641764, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45551451, Length=362, Percent_Identity=24.3093922651934, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44230; Mature: 44230

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINN
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTAVDGTPGLKKAIIAKFKRDNNLDYQANQILVSCGGKQSFFNLALALLNKGDEVI
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCEECEEEEECCCCHHHHHHHHHHHCCCCCEE
IPAPYWVSYPDMVIIAEGTPVIVKCGEDQRFKITPEQLEAAITPNTRLLVLNSPSNPTGM
ECCCCEECCCCEEEEECCCEEEEECCCCCEEEECHHHHHEEECCCEEEEEEECCCCCCEE
IYTKAELEALADVLRKHPQVYIASDDMYEPIRWEDEFYNIATVAPDLYDRTLVLNGVSKA
EEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHEEEEEECCCHHCCEEEEECCHHH
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLEPMIEAFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RHDLVVNGLNEIHGISCLPADGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPG
HHHHHHHCHHHHCCCEEECCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCEEEECC
DAFGLGGFMRISYATADDVLVDALARIKKAADSIEGIDAAIASIEAEKNA
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINN
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTAVDGTPGLKKAIIAKFKRDNNLDYQANQILVSCGGKQSFFNLALALLNKGDEVI
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCEECEEEEECCCCHHHHHHHHHHHCCCCCEE
IPAPYWVSYPDMVIIAEGTPVIVKCGEDQRFKITPEQLEAAITPNTRLLVLNSPSNPTGM
ECCCCEECCCCEEEEECCCEEEEECCCCCEEEECHHHHHEEECCCEEEEEEECCCCCCEE
IYTKAELEALADVLRKHPQVYIASDDMYEPIRWEDEFYNIATVAPDLYDRTLVLNGVSKA
EEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHEEEEEECCCHHCCEEEEECCHHH
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLEPMIEAFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RHDLVVNGLNEIHGISCLPADGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPG
HHHHHHHCHHHHCCCEEECCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCEEEECC
DAFGLGGFMRISYATADDVLVDALARIKKAADSIEGIDAAIASIEAEKNA
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA