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The map label for this gene is trpG

Identifier: 50085543

GI number: 50085543

Start: 2423066

End: 2423650

Strand: Direct

Name: trpG

Synonym: ACIAD2461

Alternate gene names: 50085543

Gene position: 2423066-2423650 (Clockwise)

Preceding gene: 50085542

Following gene: 50085544

Centisome position: 67.33

GC content: 41.88

Gene sequence:

>585_bases
ATGCTTCTCATGATCGACAATTACGACTCCTTTACGTATAACATCGTCCAGTATTTTGGCGAGTTAAATCAAGACGTTAA
AGTTGTTCGCAATGACCAAGTCACTCTTGAGGACATTGAACGATGGCAGCCGAAGTATTTGGTGGTCGGTCCCGGCCCTT
GTTCTCCAACTGAAGCTGGAATTTCTATTCCTGCAATTCATCATTTTGCAGGCAGAATCCCATTACTTGGTGTTTGTTTA
GGACATCAGGCAATTGGACAGGCTTTTGGGGGCAATATTATTCGAGCCAAAACCGTGATGCATGGTCGTTTATCGGATAT
GTATCATACGGATAAAGGGATTTTTAGCAATTTGCCTTCCCCTTTTTCAGCAACACGTTATCACTCCTTAGTGATTGAAC
AGGAAAGTTTACCTGAGTGTCTGGAAGTGACCTGCTGGACCAACCAAAATGATGGTTCAATCGAAGAAATCATGGGCGTT
AAACATAAGACATTACCTGTAGAGGGTGTGCAGTTTCATCCAGAATCGATTTTGAGCCAGCATGGACACCAAATCTTCAA
GAATTTTTTAGAGATTTATGCATAA

Upstream 100 bases:

>100_bases
CGGCTTTATTTTGAATTAAAATCTTAAAATGGATTGCCAAATGGACATTCCAAGCAAGCTAATTAAATATCTAACTAATT
TTCAATAGGTTGCAATTAAA

Downstream 100 bases:

>100_bases
ATGAATATTCAACAAGCATTAAACCATATCACCAAAAATATTCATCTGACCCAAGCGCAAATGGAAGATGTGATGCGTAG
CATCATGCAAGGCGAAGCCA

Product: anthranilate synthase component II (glutamine amido-transferase)

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MLLMIDNYDSFTYNIVQYFGELNQDVKVVRNDQVTLEDIERWQPKYLVVGPGPCSPTEAGISIPAIHHFAGRIPLLGVCL
GHQAIGQAFGGNIIRAKTVMHGRLSDMYHTDKGIFSNLPSPFSATRYHSLVIEQESLPECLEVTCWTNQNDGSIEEIMGV
KHKTLPVEGVQFHPESILSQHGHQIFKNFLEIYA

Sequences:

>Translated_194_residues
MLLMIDNYDSFTYNIVQYFGELNQDVKVVRNDQVTLEDIERWQPKYLVVGPGPCSPTEAGISIPAIHHFAGRIPLLGVCL
GHQAIGQAFGGNIIRAKTVMHGRLSDMYHTDKGIFSNLPSPFSATRYHSLVIEQESLPECLEVTCWTNQNDGSIEEIMGV
KHKTLPVEGVQFHPESILSQHGHQIFKNFLEIYA
>Mature_194_residues
MLLMIDNYDSFTYNIVQYFGELNQDVKVVRNDQVTLEDIERWQPKYLVVGPGPCSPTEAGISIPAIHHFAGRIPLLGVCL
GHQAIGQAFGGNIIRAKTVMHGRLSDMYHTDKGIFSNLPSPFSATRYHSLVIEQESLPECLEVTCWTNQNDGSIEEIMGV
KHKTLPVEGVQFHPESILSQHGHQIFKNFLEIYA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI1789760, Length=190, Percent_Identity=56.8421052631579, Blast_Score=243, Evalue=9e-66,
Organism=Escherichia coli, GI1787517, Length=192, Percent_Identity=34.8958333333333, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786215, Length=162, Percent_Identity=26.5432098765432, Blast_Score=60, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=44.2708333333333, Blast_Score=178, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6324361, Length=213, Percent_Identity=31.924882629108, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRPG_ACIAD (P00902)

Other databases:

- EMBL:   M36636
- EMBL:   CR543861
- PIR:   A01123
- RefSeq:   YP_047053.1
- ProteinModelPortal:   P00902
- SMR:   P00902
- STRING:   P00902
- GeneID:   2880739
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2461
- NMPDR:   fig|62977.3.peg.2062
- eggNOG:   COG0512
- HOGENOM:   HBG292341
- OMA:   YNVVQYL
- PhylomeDB:   P00902
- ProtClustDB:   CLSK2307483
- BioCyc:   ASP62977:ACIAD2461-MONOMER
- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221
- PRINTS:   PR00097
- PRINTS:   PR00096
- TIGRFAMs:   TIGR00566

Pfam domain/function: PF00117 GATase

EC number: =4.1.3.27

Molecular weight: Translated: 21794; Mature: 21794

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 79-79 ACT_SITE 173-173 ACT_SITE 175-175

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNIVQYFGELNQDVKVVRNDQVTLEDIERWQPKYLVVGPGPCSPTEAG
CEEEEECCCCHHHHHHHHHHHCCCCCEEHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISIPAIHHFAGRIPLLGVCLGHQAIGQAFGGNIIRAKTVMHGRLSDMYHTDKGIFSNLPS
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHHCCCC
PFSATRYHSLVIEQESLPECLEVTCWTNQNDGSIEEIMGVKHKTLPVEGVQFHPESILSQ
CCCHHHHHHEEECCCCCCCHHEEEEECCCCCCCHHHHHCCCCCCCCCCCCEECHHHHHHH
HGHQIFKNFLEIYA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MLLMIDNYDSFTYNIVQYFGELNQDVKVVRNDQVTLEDIERWQPKYLVVGPGPCSPTEAG
CEEEEECCCCHHHHHHHHHHHCCCCCEEHCCCCCCHHHHHHCCCCEEEECCCCCCCCCCC
ISIPAIHHFAGRIPLLGVCLGHQAIGQAFGGNIIRAKTVMHGRLSDMYHTDKGIFSNLPS
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCHHHHCCCC
PFSATRYHSLVIEQESLPECLEVTCWTNQNDGSIEEIMGVKHKTLPVEGVQFHPESILSQ
CCCHHHHHHEEECCCCCCCHHEEEEECCCCCCCHHHHHCCCCCCCCCCCCEECHHHHHHH
HGHQIFKNFLEIYA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6599977